LOCUS       NM_028041               3944 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus DEAD box helicase 54 (Ddx54), transcript variant 1,
            mRNA.
ACCESSION   NM_028041 XM_993864
VERSION     NM_028041.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3944)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3944)
  AUTHORS   Oizumi,H., Miyamoto,Y., Seiwa,C., Yamamoto,M., Yoshioka,N.,
            Iizuka,S., Torii,T., Ohbuchi,K., Mizoguchi,K., Yamauchi,J. and
            Asou,H.
  TITLE     Lethal adulthood myelin breakdown by oligodendrocyte-specific Ddx54
            knockout
  JOURNAL   iScience 26 (10), 107448 (2023)
   PUBMED   37720086
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3944)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 3944)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   5  (bases 1 to 3944)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125183.4.
            
            On Mar 9, 2023 this sequence version replaced NM_028041.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC043699.1, AK147715.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-190               AC125183.4         97960-98149         c
            191-320             AC125183.4         94178-94307         c
            321-391             AC125183.4         93056-93126         c
            392-580             AC125183.4         92478-92666         c
            581-630             AC125183.4         92341-92390         c
            631-672             AC125183.4         91620-91661         c
            673-768             AC125183.4         91407-91502         c
            769-890             AC125183.4         90887-91008         c
            891-952             AC125183.4         90733-90794         c
            953-1084            AC125183.4         90508-90639         c
            1085-1295           AC125183.4         89441-89651         c
            1296-1430           AC125183.4         87951-88085         c
            1431-1667           AC125183.4         87458-87694         c
            1668-1741           AC125183.4         87301-87374         c
            1742-1933           AC125183.4         86537-86728         c
            1934-2076           AC125183.4         85422-85564         c
            2077-2190           AC125183.4         85227-85340         c
            2191-2295           AC125183.4         84761-84865         c
            2296-2411           AC125183.4         84317-84432         c
            2412-3944           AC125183.4         82674-84206         c
FEATURES             Location/Qualifiers
     source          1..3944
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 60.63 cM"
     gene            1..3944
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /note="DEAD box helicase 54"
                     /db_xref="GeneID:71990"
                     /db_xref="MGI:MGI:1919240"
     exon            1..190
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /inference="alignment:Splign:2.1.0"
     CDS             20..2644
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /EC_number="3.6.4.13"
                     /note="DEAD box protein 54; DEAD (Asp-Glu-Ala-Asp) box
                     polypeptide 54"
                     /codon_start=1
                     /product="ATP-dependent RNA helicase DDX54"
                     /protein_id="NP_082317.1"
                     /db_xref="CCDS:CCDS39241.1"
                     /db_xref="GeneID:71990"
                     /db_xref="MGI:MGI:1919240"
                     /translation="MAAGRRVGPGPPSRPTMAPWKKKRLRKRRTGASQGRDSDSDDGE
                     FEIQAEDDARARKLGPGRALPSFPTSECVSDVEPDTREMVRAQNKKKKKSGGFQSMGL
                     SYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERLKAR
                     SAQTGARALILSPTRELALQTMKFTKELGKFTGLKTALILGGDKMEDQFAALHENPDI
                     IIATPGRLVHVAVEMNLKLQSVEYVVFDEADRLFEMGFAEQLQEIIGRLPGGHQTVLF
                     SATLPKLLVEFARAGLTEPVLIRLDVDSKLNEQLKTSFLLVREDTKAAVLLYLLQNVV
                     RPQDQTVVFVATKHHAEYLTELLMGQGVSCAHIYSALDQTARKINLAKFTHNKCSTLI
                     VTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEVPYLL
                     DLHLFLGRSVTLARPCEEPSVADAVGRDGVLGRVPQSVVDDEDSSLQTAMGASLDLQG
                     LHRVANNAQQQYVRSRPAPSPESIKRAKELDLAELGLHPLFSSCFEEGELQRLRLVDS
                     IKNYRTRTTIFEINASSKDPSSQMMRAKRQRDRKAVASFQQRRQERQEGPADPAPQRE
                     LPQEEEEEMVETVEGVFTEVVGQKRPRPGPSQGAKRRRMETRQRDQEFYVPYRPKDFD
                     SERGLSVSGAGGAFEQQVAGAVLDLMGDEAQNMSRGQQQLKWDRKKKRFVGQSGQEDK
                     KKIKTESGRFISSSYKRDLYQKWKQKQKIDDRDSEEEGPSNQRGPGPRRGGKRGRSQG
                     TSQPRASSVPAGRMRSELKTKEQILKQRRQAQKQRFLQRGGLKQLSARNRRRAQELRQ
                     GAFGRGAPSRKGKMRKRM"
     exon            191..320
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /inference="alignment:Splign:2.1.0"
     exon            321..391
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /inference="alignment:Splign:2.1.0"
     exon            392..580
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /inference="alignment:Splign:2.1.0"
     exon            581..630
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /inference="alignment:Splign:2.1.0"
     exon            631..672
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /inference="alignment:Splign:2.1.0"
     exon            673..768
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /inference="alignment:Splign:2.1.0"
     exon            769..890
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /inference="alignment:Splign:2.1.0"
     exon            891..952
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /inference="alignment:Splign:2.1.0"
     exon            953..1084
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /inference="alignment:Splign:2.1.0"
     exon            1085..1295
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /inference="alignment:Splign:2.1.0"
     exon            1296..1430
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /inference="alignment:Splign:2.1.0"
     exon            1431..1667
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /inference="alignment:Splign:2.1.0"
     exon            1668..1741
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /inference="alignment:Splign:2.1.0"
     exon            1742..1933
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /inference="alignment:Splign:2.1.0"
     exon            1934..2076
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /inference="alignment:Splign:2.1.0"
     exon            2077..2190
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /inference="alignment:Splign:2.1.0"
     exon            2191..2295
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /inference="alignment:Splign:2.1.0"
     exon            2296..2411
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /inference="alignment:Splign:2.1.0"
     exon            2412..3944
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2957..2962
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /note="hexamer: AATAAA"
     polyA_site      2979
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /note="major polyA site"
     polyA_site      3190
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
     regulatory      3914..3919
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
                     /note="hexamer: GATAAA"
     polyA_site      3944
                     /gene="Ddx54"
                     /gene_synonym="2410015A15Rik; DP97"
ORIGIN      
        1 gtctaagagc ccggcccgca tggctgctgg cagacgtgtg ggacctggcc cgccgtcgcg
       61 tcccaccatg gcgccgtgga agaagaagag gctgcggaaa cgccgaactg gggcttccca
      121 aggccgcgac agcgactcgg atgacggcga gttcgagatc caggcggagg atgacgcccg
      181 ggcgaggaag ctgggccctg gcagagcctt gccctcattt cctacctcag agtgcgtatc
      241 agatgtggag cccgacactc gggagatggt gcgagcccag aacaagaaaa agaagaagtc
      301 tggaggcttc cagtccatgg gcctgagtta ccctgtgttc aaggggatca tgaaaaaggg
      361 ctacaaggtg ccgacgccca tccagaggaa gaccatcccc gtgatcttgg atggcaagga
      421 tgtggtggcc atggcccgga caggcagtgg caagacggcc tgcttcctcc tcccgatgtt
      481 tgagcggctg aaggcacgca gtgcacagac gggggctcga gccctcatcc tctcacccac
      541 ccgggagctg gccctgcaga ccatgaagtt cactaaagag ctaggcaagt tcaccggcct
      601 caagactgcc ttgatcctgg gtggagacaa aatggaagac cagtttgcag ccctgcacga
      661 gaaccctgac ataatcattg ccacccctgg gcgtctggtg catgtggctg tggagatgaa
      721 cttgaagctg cagagtgtgg agtatgtggt gttcgatgaa gcagacaggc tctttgaaat
      781 gggctttgct gagcagctac aggagatcat aggccgcctt cctgggggcc accagacggt
      841 gctgttctca gctacactgc ccaagctgct ggtggaattt gcacgggcag gcctcacaga
      901 gcccgtgctc atccgcctgg acgtagactc caagctcaat gagcagctca agacctcctt
      961 cctccttgtg cgcgaagaca ccaaggctgc tgtgctcctc tacctgctgc agaatgtcgt
     1021 tcggccccag gaccagactg tggtgtttgt agccacaaag caccatgcgg agtacctcac
     1081 agagttgctg atgggccagg gtgtgagttg cgcccacatc tatagtgcct tggaccagac
     1141 ggcccgcaag atcaacttgg ccaagttcac acacaacaaa tgttccaccc tcatcgtgac
     1201 tgacctggcc gcccggggcc tggacatccc actgctggac aacgtcatca actacagctt
     1261 ccctgccaag ggcaagctct tcctgcaccg agtgggccgt gtggcccgag caggccgaag
     1321 tggcacagcc tattctttgg tggccccaga cgaggtcccc tacctgcttg acctacacct
     1381 gttcctgggc cgctctgtca ccctggcccg tccttgtgag gagccttcag tggcagatgc
     1441 ggttggcagg gacggagtgc tgggtcgcgt gccccagagt gtagtggatg atgaggacag
     1501 cagcctgcag actgccatgg gggcatccct ggatcttcag ggcctgcacc gcgtggccaa
     1561 caacgctcag cagcagtatg tgcgctcacg gccagcgccc tcgcctgagt ccatcaagag
     1621 agccaaggag ctggacctgg cagagctggg cttgcaccca ctcttcagct catgctttga
     1681 ggagggagag ctccaacgcc tgaggctggt ggacagcatc aagaactatc gcacgcgcac
     1741 aaccatcttt gagatcaatg cctccagcaa ggacccaagc agccaaatga tgcgtgccaa
     1801 gcggcagagg gaccggaaag ctgttgccag tttccagcag cggcgccagg aaaggcagga
     1861 aggcccagct gacccagccc cccagaggga gctgcctcag gaggaggagg aggagatggt
     1921 tgagactgta gagggtgtct tcacagaagt cgtgggccag aaacggccaa ggccgggacc
     1981 cagccaagga gccaagaggc ggaggatgga gacccgtcag cgagaccagg agttttatgt
     2041 cccctaccgg cccaaggatt tcgacagtga gcgggggctg agtgtcagtg gggctggagg
     2101 ggcctttgag cagcaggtgg ctggtgcagt cctggacctg atgggggatg aagcacagaa
     2161 catgagccgg gggcagcagc agctcaagtg ggaccggaag aagaagcggt ttgtggggca
     2221 gtcaggccaa gaagacaaga aaaagatcaa gacagagagc ggccggttta tcagcagctc
     2281 ttacaagcgg gatctctacc agaagtggaa gcagaagcag aaaattgatg accgggactc
     2341 cgaggaagaa gggccatcca accagcgagg ccctgggccc cgcagaggtg gaaagcgagg
     2401 tcgtagtcaa ggcacatccc agccccgagc ttccagtgta cccgcaggcc gcatgcgctc
     2461 ggaactcaag accaaggagc aaatcctcaa gcagcgccgg caagctcaga agcagcgctt
     2521 cctgcagcga gggggcctga agcagctttc agcacgcaac cgacgccgag cccaggagct
     2581 gcgccagggc gcctttggcc ggggtgctcc ctccaggaag ggcaagatga ggaaaaggat
     2641 gtgaggagcc agacgcagcc ctggggcttc ctggtagccc cgggtgtgga cgtcagggac
     2701 tatgtccatg tgctgttgga agatccttcc acaggcgctg ctctgtgagg agtagtgcca
     2761 tatggccaca gagcaacagc tgcttttgac tgggacattg ggtgacctct gaaaggatgc
     2821 ataggagtct agctatgcaa agcaggcaga cccaagtcct gaccctgcaa gtcacagcgg
     2881 cttctggttc cacaccttca ggattcagag atcagggccg tgtggatgcc tctgacccag
     2941 cattgagttt taatgtaata aactttactg cctctagtag accaggagtg tggcttcctc
     3001 aggatgtttt tggaaggtgt ctcagctgtt gttgaggctg agagcaggtg gccatgcctg
     3061 cgtgtccctc ctggtcactg agatgaggaa aatgagtcac ccaaggcagc tcaggactgc
     3121 tgcggggcag agaaaggctg tggtggcatt gcccttcttc acatggaaga gagaaagcag
     3181 cctgcgccaa ccctcgtgtc ttcattctgc tggtggcttt ttccacctct tgcttgaggt
     3241 cctgggtgtg tgtgtgtgaa gcatcctcca gtagccagac cccagtgcag gtcaggcaca
     3301 cattggggac taccccgttg ggcccgaaga gcagatggta ccaataatcc cctgccgctc
     3361 agatccactg tacatagcaa gtgcacatcc tggagtgcac tgggctccat ctgagcttgt
     3421 ccaatgcccc cccccccagc cagctgggag aggcctgtcc ccaagcctgt tgtggtggat
     3481 ggagtgacca gcccagctgt caaccccatt gtctacttaa ctgagttcat actgaatgtc
     3541 ccgtggaagg ctcacaatgg cgtgaggcgt caccgctctg tcttgcccag gagaaaggat
     3601 agtcagagag cggttacgtt gagcctgcac accaagaaat gtgggacttg gtccctcagg
     3661 tccccttcac cgttcgccag gccggattag gaagcagtag ctgtaggctg agccagggca
     3721 agtttggcca gtgtggctga gatgttcatg ataaaccgct tcacctgggg gcagagatga
     3781 catggccaga gtacatcctc tccccacccc cacagaggca ggcccagggc aggggtgggg
     3841 ctggaaccct gactggagag gcactgatag tgtctagccc agcctcctaa aagtatcctt
     3901 tgttctgttt attgataaaa gtacaactca aacttggcct ctaa
//
