LOCUS       NP_080636                455 aa            linear   ROD 30-APR-2024
DEFINITION  probable ATP-dependent RNA helicase DDX47 [Mus musculus].
ACCESSION   NP_080636
VERSION     NP_080636.2
DBSOURCE    REFSEQ: accession NM_026360.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 455)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 455)
  AUTHORS   Combes,A.N., Lesieur,E., Harley,V.R., Sinclair,A.H., Little,M.H.,
            Wilhelm,D. and Koopman,P.
  TITLE     Three-dimensional visualization of testis cord morphogenesis, a
            novel tubulogenic mechanism in development
  JOURNAL   Dev Dyn 238 (5), 1033-1041 (2009)
   PUBMED   19334288
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY123864.1, AK010310.1 and BB682132.1.
            
            On Dec 18, 2002 this sequence version replaced NP_080636.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC095944.1, AK010310.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 65.77 cM"
     Protein         1..455
                     /product="probable ATP-dependent RNA helicase DDX47"
                     /EC_number="3.6.4.13"
                     /note="DEAD box protein 47; DEAD (Asp-Glu-Ala-Asp) box
                     polypeptide 47"
                     /calculated_mol_wt=50508
     Region          1..21
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9CWX9.2)"
     Site            2
                     /site_type="acetylation"
                     /note="N-acetylalanine.
                     /evidence=ECO:0000250|UniProtKB:Q9H0S4; propagated from
                     UniProtKB/Swiss-Prot (Q9CWX9.2)"
     Site            9
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9H0S4; propagated from
                     UniProtKB/Swiss-Prot (Q9CWX9.2)"
     Region          23..453
                     /region_name="SrmB"
                     /note="Superfamily II DNA and RNA helicase [Replication,
                     recombination and repair]; COG0513"
                     /db_xref="CDD:440279"
     Region          24..52
                     /region_name="Q motif"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9CWX9.2)"
     Site            149
                     /site_type="phosphorylation"
                     /note="Phosphothreonine.
                     /evidence=ECO:0000250|UniProtKB:Q9H0S4; propagated from
                     UniProtKB/Swiss-Prot (Q9CWX9.2)"
     Region          174..177
                     /region_name="DEAD box"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9CWX9.2)"
     Region          412..455
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9CWX9.2)"
     CDS             1..455
                     /gene="Ddx47"
                     /gene_synonym="4930588A18Rik"
                     /coded_by="NM_026360.3:31..1398"
                     /db_xref="CCDS:CCDS20643.1"
                     /db_xref="GeneID:67755"
                     /db_xref="MGI:MGI:1915005"
ORIGIN      
        1 maadeepdsp sgalqtaaee eetktfkdlg vtdvlceacd qlgwakptki qieaiplalq
       61 grdiiglaet gsgktgafal pilnalletp qrlfalvltp trelafqise qfealgssig
      121 vqcavivggi dsmsqslala kkphiviatp grlidhlent kgfnlralky lvmdeadril
      181 nmdfetevdk ilkviprdrk tflfsatmtk kvqklqraal knpvkcavss kyqtveklqq
      241 yylfipskfk dtylvyilne lagnsfmifc stcnntqrta lllrnlgfta iplhgqmsqs
      301 krlgslnkfk akarsillat dvasrgldip hvdvvvnfdi pthskdyihr vgrtaragrs
      361 gkaitfvtqy dvelfqrieh ligkklpvfp tqdeevmmlt ervneaqrfa rmelrehgek
      421 kkrkredagd dddkegaigv rnkvaggkmk krkgr
//
