LOCUS       NM_001191044            2209 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus DEAD box helicase 43 (Ddx43), mRNA.
ACCESSION   NM_001191044 XM_001478854 XM_003084798
VERSION     NM_001191044.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2209)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2209)
  AUTHORS   Linley,A.J., Mathieu,M.G., Miles,A.K., Rees,R.C., McArdle,S.E. and
            Regad,T.
  TITLE     The helicase HAGE expressed by malignant melanoma-initiating cells
            is required for tumor cell proliferation in vivo
  JOURNAL   J Biol Chem 287 (17), 13633-13643 (2012)
   PUBMED   22393060
  REMARK    GeneRIF: the helicase HAGE is required for ABCB5+ MMIC-dependent
            tumor growth through promoting RAS protein expression
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC138587.11
            and AC158987.3.
            
            On or before Jan 13, 2011 this sequence version replaced
            XM_003084798.1, XM_001478854.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849384,
                              SAMN01164133 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-350               AC138587.11        179277-179626
            351-406             AC138587.11        182541-182596
            407-533             AC138587.11        184349-184475
            534-599             AC138587.11        185850-185915
            600-665             AC158987.3         41995-42060
            666-747             AC158987.3         45930-46011
            748-904             AC158987.3         51171-51327
            905-1023            AC158987.3         51772-51890
            1024-1134           AC158987.3         52545-52655
            1135-1276           AC158987.3         53322-53463
            1277-1377           AC158987.3         53803-53903
            1378-1465           AC158987.3         56242-56329
            1466-1593           AC158987.3         57616-57743
            1594-1703           AC158987.3         57912-58021
            1704-1842           AC158987.3         58791-58929
            1843-1930           AC158987.3         60168-60255
            1931-2071           AC158987.3         61277-61417
            2072-2209           AC158987.3         63031-63168
FEATURES             Location/Qualifiers
     source          1..2209
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 43.65 cM"
     gene            1..2209
                     /gene="Ddx43"
                     /note="DEAD box helicase 43"
                     /db_xref="GeneID:100048658"
                     /db_xref="MGI:MGI:3642857"
     exon            1..350
                     /gene="Ddx43"
                     /inference="alignment:Splign:2.1.0"
     exon            351..406
                     /gene="Ddx43"
                     /inference="alignment:Splign:2.1.0"
     exon            407..533
                     /gene="Ddx43"
                     /inference="alignment:Splign:2.1.0"
     exon            534..665
                     /gene="Ddx43"
                     /inference="alignment:Splign:2.1.0"
     exon            666..747
                     /gene="Ddx43"
                     /inference="alignment:Splign:2.1.0"
     exon            748..904
                     /gene="Ddx43"
                     /inference="alignment:Splign:2.1.0"
     exon            905..1023
                     /gene="Ddx43"
                     /inference="alignment:Splign:2.1.0"
     exon            1024..1134
                     /gene="Ddx43"
                     /inference="alignment:Splign:2.1.0"
     exon            1135..1276
                     /gene="Ddx43"
                     /inference="alignment:Splign:2.1.0"
     exon            1277..1377
                     /gene="Ddx43"
                     /inference="alignment:Splign:2.1.0"
     exon            1378..1465
                     /gene="Ddx43"
                     /inference="alignment:Splign:2.1.0"
     exon            1466..1593
                     /gene="Ddx43"
                     /inference="alignment:Splign:2.1.0"
     exon            1594..1703
                     /gene="Ddx43"
                     /inference="alignment:Splign:2.1.0"
     exon            1704..1842
                     /gene="Ddx43"
                     /inference="alignment:Splign:2.1.0"
     exon            1843..1930
                     /gene="Ddx43"
                     /inference="alignment:Splign:2.1.0"
     exon            1931..2071
                     /gene="Ddx43"
                     /inference="alignment:Splign:2.1.0"
     exon            2072..2209
                     /gene="Ddx43"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2190..2195
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ddx43"
                     /note="hexamer: AATAAA"
     polyA_site      2209
                     /gene="Ddx43"
                     /note="major polyA site"
ORIGIN      
        1 ggactggcgg gcgagctcgc gggcggcagc ggagtttttc cgacgccgcg gcctgtgcag
       61 ctgagtctgg aacgacgtgc gacgcgcggc tctcctcaga gccatgtcta ggcgggaacc
      121 cgcagccaac gcttcctcct cgggcgttgc tccccggcga agctcgaccg ggtcccgggg
      181 cgccgaccgg acagcgacgg aggagacgaa ccggagaggc cgggtcggta gcaggggtgc
      241 gggcggcggc tggagagagc ccgccggggc cgccgaggct acggccgccg gccgccgcga
      301 accgccgctc tgcttcgggg tgaagaacga tgtggtgggc gcggtgatag gtcgtggtgg
      361 gtcaaaaatt agagaaatcc aaaatacaac gaacactagg atacaggtaa taaaaggaaa
      421 tcctgaggca gaaatcaaaa tttttggtaa taaagccatg caaacaaaag caaaaacagt
      481 gatagataat gttgttaaaa aacaacaaaa ttacattcca ggacaaagag ttggtattat
      541 tgcattccaa cctaccgttg gagcagatac cagcacaagt gagagtgtaa cagacgatca
      601 gccattgata gattgggatc aaattcgaga agatgctttg aaatgggaaa agaaaaagtg
      661 ggcagattta cctccaatta agaaaaactt ttacatagag tcagcaacga caagctcaat
      721 gtcacaagtg caaatagaca actggaggaa agaaaatttt aatataacat gtgatgactt
      781 gaaagatggt gagaagcgtc ctatccccaa ccctatatgt aaatttgaag atgcctttca
      841 aagttaccca gaagtaatgg aaaacattaa aagagcaggc tttcaaaaac ctacaccgat
      901 tcagtcacag gcatggccaa tagttctaca aggaatagat cttattggag tagcacaaac
      961 tggaacaggg aagacactgt cctatttaat gcctggattt attcatctag actctcaacc
     1021 actagctaga gaacaaagaa atgggcctgg catgttagtt cttacgccca cccgggaatt
     1081 agcccttcaa gtagaagctg aatgttctaa atattcatat ggtgatctta aaagtgtttg
     1141 tgtatatggt ggtggtgata gagatggaca aatacaagat gtttcaaaag gtgtagacat
     1201 cattattgca actcctggaa gattgaatga cctacaaatg aataactttg tcaatctgaa
     1261 aagtgtaacc tatttggttt tagatgaagc agacaagatg ctggacatgg gatttgaacc
     1321 ccagataatg aagattttgt tagatgtacg cccagaccgg cagactatta tgacaagcgc
     1381 tacttggcca tatgccgtcc gccgtcttgc acaatcttat ttgaaagaac caatgattgt
     1441 ctatgttggt actttggatc tagttgctgt aagtacagtg aaacaaaata taatcattac
     1501 cacagaagaa gagaaacgaa ctcatatcca gaccttcctc gagaatatgt cacctaaaga
     1561 caaagtcatt gtctttgtca gcagaaaagc cgttgctgat cacttatcaa gtgatctgat
     1621 tctccgacac atatcagtgg agtctctgca cggcaacaga gaacagagtg accgagagaa
     1681 agcgttagag aactttaaga caggtaaagt gagaatactt attgctactg acttggcatc
     1741 tcgaggtctt gatgtccatg atatcactca tgtctacaat tatgattttc cacggaacat
     1801 tgaagaatat gtacacagag tagggcgcac tgggagagca gggcgcactg gaatgtcaat
     1861 tacccttatc acaagaaatg attggagggt tgccactgaa ttgattaata ttctagaaag
     1921 agcaaatcag aatatcccag aggaacttgt cttaatggct gagagataca aagcaaataa
     1981 actaaaaaga gagatggaaa aaaaaatggg aagacctcaa ggaaagcccc agaagtttta
     2041 ctaatgttgc gtggagcact aggtgccgca ggattcaaga ttgtagtcaa agtggaagtg
     2101 ttgaaacata cgtcactatg gagagacttg gctgattctt aaaataatag tgtgttaaaa
     2161 tgtagaattc aatgttttat actttcttta ataaaacagt agtttttaa
//
