LOCUS       NM_001145885            2850 bp    mRNA    linear   ROD 24-OCT-2024
DEFINITION  Mus musculus DEAD box helicase 4 (Ddx4), transcript variant 1,
            mRNA.
ACCESSION   NM_001145885
VERSION     NM_001145885.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2850)
  AUTHORS   Dong,M.Z., Ouyang,Y.C., Gao,S.C., Gu,L.J., Guo,J.N., Sun,S.M.,
            Wang,Z.B. and Sun,Q.Y.
  TITLE     Protein phosphatase 4 maintains the survival of primordial
            follicles by regulating autophagy in oocytes
  JOURNAL   Cell Death Dis 15 (9), 658 (2024)
   PUBMED   39245708
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2850)
  AUTHORS   Luo,X., Zhang,D., Zheng,J., Liu,H., Sun,L., Guo,H., Wang,L. and
            Cui,S.
  TITLE     Casein kinase 1alpha mediates estradiol secretion via CYP19A1
            expression in mouse ovarian granulosa cells
  JOURNAL   BMC Biol 22 (1), 176 (2024)
   PUBMED   39183304
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2850)
  AUTHORS   Hayashi,Y., Kaneko,J., Ito-Matsuoka,Y., Takehara,A., Funakoshi,M.,
            Maezawa,S., Shirane,K., Furuya,S. and Matsui,Y.
  TITLE     Control of epigenomic landscape and development of fetal male germ
            cells through L-serine metabolism
  JOURNAL   iScience 27 (9), 110702 (2024)
   PUBMED   39262797
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2850)
  AUTHORS   Wen,C., Cao,L., Wang,S., Xu,W., Yu,Y., Zhao,S., Yang,F., Chen,Z.J.,
            Zhao,S., Yang,Y. and Qin,Y.
  TITLE     MCM8 interacts with DDX5 to promote R-loop resolution
  JOURNAL   EMBO J 43 (14), 3044-3071 (2024)
   PUBMED   38858601
REFERENCE   5  (bases 1 to 2850)
  AUTHORS   Wen,Y., Zhou,S., Gui,Y., Li,Z., Yin,L., Xu,W., Feng,S., Ma,X.,
            Gan,S., Xiong,M., Dong,J., Cheng,K., Wang,X. and Yuan,S.
  TITLE     hnRNPU is required for spermatogonial stem cell pool establishment
            in mice
  JOURNAL   Cell Rep 43 (4), 114113 (2024)
   PUBMED   38625792
REFERENCE   6  (bases 1 to 2850)
  AUTHORS   Tanaka,S.S., Toyooka,Y., Akasu,R., Katoh-Fukui,Y., Nakahara,Y.,
            Suzuki,R., Yokoyama,M. and Noce,T.
  TITLE     The mouse homolog of Drosophila Vasa is required for the
            development of male germ cells
  JOURNAL   Genes Dev 14 (7), 841-853 (2000)
   PUBMED   10766740
REFERENCE   7  (bases 1 to 2850)
  AUTHORS   Abe,K. and Noce,T.
  TITLE     A DEAD-family protein gene, Ddx4, encoding a murine homolog of
            Drosophila vasa maps to the distal end of mouse chromosome 13
  JOURNAL   Mamm Genome 8 (8), 622-623 (1997)
   PUBMED   9250878
REFERENCE   8  (bases 1 to 2850)
  AUTHORS   Yen,C.H., Pazik,J., Zhang,Y. and Elliott,R.W.
  TITLE     An interstitial telomere array proximal to the distal telomere of
            mouse chromosome 13
  JOURNAL   Mamm Genome 8 (6), 411-417 (1997)
   PUBMED   9166585
REFERENCE   9  (bases 1 to 2850)
  AUTHORS   White,R.A., Dowler,L.L., Angeloni,S.V. and Koeller,D.M.
  TITLE     Assignment of Etfdh, Etfb, and Etfa to chromosomes 3, 7, and 13:
            the mouse homologs of genes responsible for glutaric acidemia type
            II in human
  JOURNAL   Genomics 33 (1), 131-134 (1996)
   PUBMED   8617498
REFERENCE   10 (bases 1 to 2850)
  AUTHORS   Fujiwara,Y., Komiya,T., Kawabata,H., Sato,M., Fujimoto,H.,
            Furusawa,M. and Noce,T.
  TITLE     Isolation of a DEAD-family protein gene that encodes a murine
            homolog of Drosophila vasa and its specific expression in germ cell
            lineage
  JOURNAL   Proc Natl Acad Sci U S A 91 (25), 12258-12262 (1994)
   PUBMED   7991615
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BE860399.1, AK133366.1 and DT906923.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and it encodes the longer protein (isoform 1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK133366.1, BC144760.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-8                 BE860399.1         1-8
            9-2847              AK133366.1         2-2840
            2848-2850           DT906923.1         76-78
FEATURES             Location/Qualifiers
     source          1..2850
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 63.87 cM"
     gene            1..2850
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /note="DEAD box helicase 4"
                     /db_xref="GeneID:13206"
                     /db_xref="MGI:MGI:102670"
     exon            1..35
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /inference="alignment:Splign:2.1.0"
     exon            36..122
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /inference="alignment:Splign:2.1.0"
     exon            123..180
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /inference="alignment:Splign:2.1.0"
     exon            181..258
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /inference="alignment:Splign:2.1.0"
     exon            259..336
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /inference="alignment:Splign:2.1.0"
     exon            337..387
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /inference="alignment:Splign:2.1.0"
     exon            388..447
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /inference="alignment:Splign:2.1.0"
     exon            448..549
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /inference="alignment:Splign:2.1.0"
     exon            550..630
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /inference="alignment:Splign:2.1.0"
     exon            631..672
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /inference="alignment:Splign:2.1.0"
     exon            673..720
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /inference="alignment:Splign:2.1.0"
     exon            721..768
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /inference="alignment:Splign:2.1.0"
     exon            769..911
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /inference="alignment:Splign:2.1.0"
     exon            912..1064
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /inference="alignment:Splign:2.1.0"
     exon            1065..1219
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /inference="alignment:Splign:2.1.0"
     exon            1220..1349
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /inference="alignment:Splign:2.1.0"
     exon            1350..1516
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /inference="alignment:Splign:2.1.0"
     exon            1517..1662
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /inference="alignment:Splign:2.1.0"
     exon            1663..1762
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /inference="alignment:Splign:2.1.0"
     exon            1763..2033
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /inference="alignment:Splign:2.1.0"
     exon            2034..2150
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /inference="alignment:Splign:2.1.0"
     exon            2151..2849
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2821..2826
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /note="hexamer: AATAAA"
     polyA_site      2849
                     /gene="Ddx4"
                     /gene_synonym="Mvh; VASA"
                     /note="major polyA site"
ORIGIN      
        1 ggccgcgagg agcccgggga gcctggagcg gagaggaacc tgaagctatc atgggagatg
       61 aagattggga ggcagaaata ctcaaacctc acgtgtcttc ctatgttcct gtatttgaga
      121 aggataaata ttcttctgga gcaaatggag acacttttaa caggacttca gcttcatcag
      181 aaatggaaga tgggccttct ggaagagatg atttcatgag aagtgggttt ccttctggaa
      241 gaagtttagg aagcagagat attggcgagt ctagtaaaaa agagaacaca tctacaactg
      301 gtggctttgg aagaggaaag ggctttggaa acagaggttt tttaaataac aagtttgaag
      361 aaggtgatag ctctggtttc tggaaagagt ctaataatga ctgtgaagat aatcagactc
      421 gaagcagagg gttttccaag cgaggtggct gccaagatgg aaacgattca gaagcatcag
      481 gcccgttcag aagaggggga agaggcagtt tccgaggctg ccgtggagga tttggtctag
      541 gaagaccaaa tagtgaatct gaccaagatc aggggacaca gcgtggtggt ggcctttttg
      601 gttctaggaa accagcagca agtgattcag gcaatggtga cacttaccaa agcagaagtg
      661 gaagtggtcg aggtggttac aaaggtttaa atgaagaagt agtaacaggt tctggaaaga
      721 attcttggaa gtcagaaact gaaggaggtg aaagcagtga tagtcaaggt ccaaaagtga
      781 catatatacc ccctcctcca ccagaggatg aggactccat ctttgcacat tatcagacag
      841 gcataaactt tgataaatat gacaccatac ttgttgaagt atctggacat gatgcaccac
      901 cggcaatttt gacttttgaa gaagctaatc tctgtcagac actgaataac aacattgcta
      961 aagctggcta tactaagctt actcctgtgc agaagtacag cattcccatt gtattagcag
     1021 gacgagattt gatggcttgt gctcaaacag ggtctgggaa gactgcagct tttctcttgc
     1081 ctattttggc tcatatgatg cgggatggaa taactgccag tcgctttaaa gaactgcagg
     1141 aaccagagtg tattattgta gcaccaactc gagaactgat caaccaaatt tacttggaag
     1201 ccagaaaatt ttcttttggg acttgtgtaa gagctgtggt catatatgga ggaacccagt
     1261 ttggtcattc agttcgacag atagtacaag ggtgtaacat attgtgtgct actccaggga
     1321 ggctgatgga catcataggc aaagaaaaga ttggcctcaa acaagtcaag tacttagttt
     1381 tggatgaagc tgatcgaatg ttggatatgg gttttggacc agagatgaag aaactaattt
     1441 cttgtccagg aatgccatca aaggaacaac gccaaaccct tttattcagt gctacttttc
     1501 cagaagaaat ccagaggttg gctggggact ttctaaagtc cagttacttg tttgtcgctg
     1561 ttgggcaagt gggaggagct tgcagagatg ttcagcagac gatccttcaa gttggccagt
     1621 attcaaaaag agaaaagctt gttgagattc tacgaaacat aggtgatgaa agaactatgg
     1681 tctttgttga aaccaagaaa aaagccgatt tcattgcaac ttttctttgt caagaaaaaa
     1741 tatcaactac aagtattcat ggtgatcggg agcagaggga gagagagcaa gctcttggag
     1801 attttcgctg tggaaagtgc ccagttcttg ttgctacttc agtggctgcc agagggcttg
     1861 atattgaaaa tgttcaacat gttatcaatt ttgaccttcc ttctaccatt gatgagtatg
     1921 ttcatcgaat tggacgcact ggccgctgtg gaaatactgg cagagcgatt tctttttttg
     1981 atactgactc tgataatcat ttagcacagc ctctagttaa agtactgtca gacgctcaac
     2041 aggatgtccc cgcatggcta gaagagattg ccttcagtac ctatgtgcct cccagcttca
     2101 gtagcagcac aagagggggg gctgtgtttg catctgttga cacgaggaag aattaccagg
     2161 gcaagcacac gttgaataca gcggggattt cttcttcaca agctcccaat ccagttgatg
     2221 acgagtcatg ggattaaagc aaacgaacat acttcaagtc tgatagtttt gatgcagaga
     2281 agaaagagtt tttattttta aaattttaac agaagtgtga aacctgatat tcttatatct
     2341 cctgttcttc tgttcttcct cccaaccttt aaaaaatagc cagcttcatt gattagttat
     2401 gtgaaatgct gacgttacaa cactgcagtt actgatacaa atggtgttag ctggaaatat
     2461 taaagcattc ttatatgttt tgcttatttc tagtatattc ttcagaaagt taagacatgt
     2521 ttcatgtcca agtgcttaag tcttagtata gtgtttatga tcctataaaa caagcaatag
     2581 gatgtgatgt gcttttgttt aattattggg tctaatttct acttgatcct ttaaaagaat
     2641 agtgtatcag tacaatgtaa taacatgatt ttcatgaaac agtagagact gaagcctttc
     2701 aaagttattt gatttttaga tcatcagaca tgtaatgaaa atggttcagt ttgcaatgtg
     2761 agctttgtac ttggtggtat gacaaatgtt tgcttttata atatacagat tttccttgca
     2821 aataaaagat gaaacacatt tccccctaaa
//
