LOCUS       NM_007916               2580 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus DEAD box helicase 19a (Ddx19a), transcript variant 1,
            mRNA.
ACCESSION   NM_007916 XM_001001073
VERSION     NM_007916.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2580)
  AUTHORS   Pinter,S., Knodel,F., Choudalakis,M., Schnee,P., Kroll,C.,
            Fuchs,M., Broehm,A., Weirich,S., Roth,M., Eisler,S.A., Zuber,J.,
            Jeltsch,A. and Rathert,P.
  TITLE     A functional LSD1 coregulator screen reveals a novel
            transcriptional regulatory cascade connecting R-loop homeostasis
            with epigenetic regulation
  JOURNAL   Nucleic Acids Res 49 (8), 4350-4370 (2021)
   PUBMED   33823549
  REMARK    GeneRIF: A functional LSD1 coregulator screen reveals a novel
            transcriptional regulatory cascade connecting R-loop homeostasis
            with epigenetic regulation.
REFERENCE   2  (bases 1 to 2580)
  AUTHORS   Zhang,K., Zhang,Y., Xue,J., Meng,Q., Liu,H., Bi,C., Li,C., Hu,L.,
            Yu,H., Xiong,T., Yang,Y., Cui,S., Bu,Z., He,X., Li,J., Huang,L. and
            Weng,C.
  TITLE     DDX19 Inhibits Type I Interferon Production by Disrupting
            TBK1-IKKepsilon-IRF3 Interactions and Promoting TBK1 and IKKepsilon
            Degradation
  JOURNAL   Cell Rep 26 (5), 1258-1272 (2019)
   PUBMED   30699353
REFERENCE   3  (bases 1 to 2580)
  AUTHORS   Rajakyla,E.K., Viita,T., Kyheroinen,S., Huet,G., Treisman,R. and
            Vartiainen,M.K.
  TITLE     RNA export factor Ddx19 is required for nuclear import of the SRF
            coactivator MKL1
  JOURNAL   Nat Commun 6, 5978 (2015)
   PUBMED   25585691
  REMARK    GeneRIF: Ddx19 is an RNA export factor required for nuclear import
            of the SRF coactivator MKL1
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2580)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2580)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   6  (bases 1 to 2580)
  AUTHORS   Yang,H.S., Jansen,A.P., Komar,A.A., Zheng,X., Merrick,W.C.,
            Costes,S., Lockett,S.J., Sonenberg,N. and Colburn,N.H.
  TITLE     The transformation suppressor Pdcd4 is a novel eukaryotic
            translation initiation factor 4A binding protein that inhibits
            translation
  JOURNAL   Mol Cell Biol 23 (1), 26-37 (2003)
   PUBMED   12482958
REFERENCE   7  (bases 1 to 2580)
  AUTHORS   Gee,S.L. and Conboy,J.G.
  TITLE     Mouse erythroid cells express multiple putative RNA helicase genes
            exhibiting high sequence conservation from yeast to mammals
  JOURNAL   Gene 140 (2), 171-177 (1994)
   PUBMED   8144024
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY302446.1, AK146548.1 and BG094410.1.
            
            On Mar 27, 2008 this sequence version replaced NM_007916.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC011270.1, AK146548.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164141 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-40                BY302446.1         1-40
            41-2570             AK146548.1         2-2531
            2571-2580           BG094410.1         1-10                c
FEATURES             Location/Qualifiers
     source          1..2580
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 57.86 cM"
     gene            1..2580
                     /gene="Ddx19a"
                     /gene_synonym="DBP5; Ddx19; Eif4a-rs1"
                     /note="DEAD box helicase 19a"
                     /db_xref="GeneID:13680"
                     /db_xref="MGI:MGI:99526"
     exon            1..157
                     /gene="Ddx19a"
                     /gene_synonym="DBP5; Ddx19; Eif4a-rs1"
                     /inference="alignment:Splign:2.1.0"
     exon            158..206
                     /gene="Ddx19a"
                     /gene_synonym="DBP5; Ddx19; Eif4a-rs1"
                     /inference="alignment:Splign:2.1.0"
     exon            207..257
                     /gene="Ddx19a"
                     /gene_synonym="DBP5; Ddx19; Eif4a-rs1"
                     /inference="alignment:Splign:2.1.0"
     exon            258..393
                     /gene="Ddx19a"
                     /gene_synonym="DBP5; Ddx19; Eif4a-rs1"
                     /inference="alignment:Splign:2.1.0"
     exon            394..486
                     /gene="Ddx19a"
                     /gene_synonym="DBP5; Ddx19; Eif4a-rs1"
                     /inference="alignment:Splign:2.1.0"
     exon            487..589
                     /gene="Ddx19a"
                     /gene_synonym="DBP5; Ddx19; Eif4a-rs1"
                     /inference="alignment:Splign:2.1.0"
     exon            590..704
                     /gene="Ddx19a"
                     /gene_synonym="DBP5; Ddx19; Eif4a-rs1"
                     /inference="alignment:Splign:2.1.0"
     exon            705..882
                     /gene="Ddx19a"
                     /gene_synonym="DBP5; Ddx19; Eif4a-rs1"
                     /inference="alignment:Splign:2.1.0"
     exon            883..1120
                     /gene="Ddx19a"
                     /gene_synonym="DBP5; Ddx19; Eif4a-rs1"
                     /inference="alignment:Splign:2.1.0"
     exon            1121..1283
                     /gene="Ddx19a"
                     /gene_synonym="DBP5; Ddx19; Eif4a-rs1"
                     /inference="alignment:Splign:2.1.0"
     exon            1284..1475
                     /gene="Ddx19a"
                     /gene_synonym="DBP5; Ddx19; Eif4a-rs1"
                     /inference="alignment:Splign:2.1.0"
     exon            1476..2575
                     /gene="Ddx19a"
                     /gene_synonym="DBP5; Ddx19; Eif4a-rs1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2556..2561
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ddx19a"
                     /gene_synonym="DBP5; Ddx19; Eif4a-rs1"
                     /note="hexamer: ATTAAA"
     polyA_site      2575
                     /gene="Ddx19a"
                     /gene_synonym="DBP5; Ddx19; Eif4a-rs1"
                     /note="major polyA site"
ORIGIN      
        1 tttttccgct ccgtgtgagt ggcacttggc gcgggcttgc gttcggcgct ggtgttggcg
       61 gggcgcggag catctctgca ggtcggctcg cgtcgggacc atggccaccg actcatgggc
      121 gctggcggtg gacgagcagg aagccgctgt caagtcgatg agcagtttgc agatcaagga
      181 agagaaagtc aaagcagaca ccaatggtgt tatcaaaacc agcaccactg cagaaaagac
      241 agaggaagag gagaaagagg acagagctgc tcagtcttta ctcaacaagc tgatcagaag
      301 caatcttgtg gataacacca accaagtgga agtcctgcag agggacccaa gctccccgct
      361 ctactcagtg aagtccttcg aagagcttcg cctgaaacct cagcttctcc aaggagtcta
      421 cgccatgggc ttcaatcgac cgtccaagat ccaggagaat gctctgccca tgatgcttgc
      481 tgaaccccca cagaacctga ttgcacagtc ccagtctggt actgggaaaa cagctgcctt
      541 tgtcctagct atgctcagca gagtggaacc agcagacaga tatcctcagt gtttgtgcct
      601 gtccccaaca tatgagctgg cattacaaac tggaaaagtg attgagcaga tgggcaagtt
      661 tcacccagaa ttgaagctag cttatgctgt tcgaggcaat aaattggaga gaggtcagaa
      721 ggtgagtgag cagattgtca ttggcacccc cgggaccgtc ttggactggt gctccaagct
      781 gaagttcatt gaccccaaga agatcaaggt gtttgttctg gacgaggctg atgtgatgat
      841 agcgactcag ggccaccaag accagagcat ccgcatccag aggatgctgc ccagaaactg
      901 ccagatgctg cttttctcgg ccacctttga agactcggtg tggaagtttg cccagaaggt
      961 ggtcccagac cccaacatca tcaagctaaa gcgtgaggag gagactctgg acaccatcaa
     1021 acagtactac gtcctctgca ataacagaga ggagaagttc caggccctgt gcaacctgta
     1081 tggggccatc accatcgccc aagccatgat cttctgccat acccgcaaaa cagctagctg
     1141 gctggcagca gagctctcaa aagagggcca ccaggtggcc ctgctgagtg gagagatgat
     1201 ggtggagcag agggctgcgg tgatcgagcg cttccgagaa ggcaaagaga aggttctggt
     1261 gaccaccaac gtgtgtgccc gtggtatcga tgttgaacag gtgtctgtcg tcatcaattt
     1321 tgacctccct gtggacaagg atgggaaccc agacaatgag acctacctgc accgcattgg
     1381 gcgcactggc cgctttggca agaggggtct ggcggtgaac atggtggaca gcaagcacag
     1441 catgaatatc ctcaacagga tccaggagca ttttaataag aagatagaaa gactggacac
     1501 agatgatttg gacgagattg agaaaatcgc caactgaggc gctcgcttct ccatgggctg
     1561 gcgccaccct cagcgctccc tgcctgggag tctagtgctt tcatggcata ggcctgacgg
     1621 gcccctcaga gaccacgggc tgagtagaga ctacctacct cattcggaat tacgtttgga
     1681 cttgacaaat ttctgcaaat agtaggggga aatctaagaa aatttacaat ttagaatata
     1741 gccctggctt ggtgtggtgg tgcacacttt tggtcccagc acttggaggg tagagacagg
     1801 aggatctcca tgaattacag accagcctgt tttacttaat gagctctagg acagccagag
     1861 ctatgtagtg agcccctgtc ttgaggaaag aactgagttc tcggcactat tcccctttaa
     1921 agccacagtt tttcttgtat ggtaatatgg ttgctaatgc ttgggctgca ggccttgttg
     1981 cccactggct ggctccctct gttttgacca atcctcaacc ttgaataaat gagaggaaaa
     2041 ggcagttcat agaggtcagg agagacattg ctatagctca cctgcctctc atagaaccag
     2101 tagagacact ctgttctcca ttcaccccca ctcaacaacc acccaccccc caccccaccc
     2161 cacccccgct tccctggtgt aatgccttgg ttatgtcttt attcttcaga ttggcagaaa
     2221 aaatggaagt cagcaaatct cagactcgag ggtcatagac aatcccattg aagatggagg
     2281 tgtctttcct cctgtacatc tagtctgtgc ctggctccat tgtttgttcc aatccatggg
     2341 acttcatgcc acgtaacaac ttagaaagga agttatgacc aagcaaaaac tctgaattat
     2401 gctatgagca gacttatggg ttacttcata cattgtatga ataaggttta taaatcagtg
     2461 gtaacacgtc attcttagaa actttaatta tgagaaattt tgctaatcat gatttgttat
     2521 ttgtattttt ctgcttacta gactaatata tgctcattaa aaatgtgtat aagaaaaaaa
//
