LOCUS       NM_029936               3368 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus DEAD box helicase 10 (Ddx10), mRNA.
ACCESSION   NM_029936 XM_001481328 XM_284494
VERSION     NM_029936.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3368)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3368)
  AUTHORS   Palmer,K., Fairfield,H., Borgeia,S., Curtain,M., Hassan,M.G.,
            Dionne,L., Yong Karst,S., Coombs,H., Bronson,R.T., Reinholdt,L.G.,
            Bergstrom,D.E., Donahue,L.R., Cox,T.C. and Murray,S.A.
  TITLE     Discovery and characterization of spontaneous mouse models of
            craniofacial dysmorphology
  JOURNAL   Dev Biol 415 (2), 216-227 (2016)
   PUBMED   26234751
REFERENCE   3  (bases 1 to 3368)
  AUTHORS   Fairfield,H., Srivastava,A., Ananda,G., Liu,R., Kircher,M.,
            Lakshminarayana,A., Harris,B.S., Karst,S.Y., Dionne,L.A.,
            Kane,C.C., Curtain,M., Berry,M.L., Ward-Bailey,P.F., Greenstein,I.,
            Byers,C., Czechanski,A., Sharp,J., Palmer,K., Gudis,P., Martin,W.,
            Tadenev,A., Bogdanik,L., Pratt,C.H., Chang,B., Schroeder,D.G.,
            Cox,G.A., Cliften,P., Milbrandt,J., Murray,S., Burgess,R.,
            Bergstrom,D.E., Donahue,L.R., Hamamy,H., Masri,A., Santoni,F.A.,
            Makrythanasis,P., Antonarakis,S.E., Shendure,J. and Reinholdt,L.G.
  TITLE     Exome sequencing reveals pathogenic mutations in 91 strains of mice
            with Mendelian disorders
  JOURNAL   Genome Res 25 (7), 948-957 (2015)
   PUBMED   25917818
REFERENCE   4  (bases 1 to 3368)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC160139.2 and AC112956.12.
            
            On or before Jun 8, 2008 this sequence version replaced
            XM_001481328.1, XM_284494.5, NM_029936.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC049261.1, AK019495.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-295               AC160139.2         110515-110809
            296-356             AC160139.2         118090-118150
            357-487             AC160139.2         120449-120579
            488-646             AC160139.2         122069-122227
            647-767             AC160139.2         123244-123364
            768-957             AC160139.2         124610-124799
            958-1084            AC160139.2         129376-129502
            1085-1247           AC160139.2         132992-133154
            1248-1332           AC160139.2         134883-134967
            1333-1434           AC160139.2         145290-145391
            1435-1522           AC160139.2         148851-148938
            1523-1611           AC160139.2         151073-151161
            1612-2083           AC160139.2         154097-154568
            2084-2203           AC112956.12        162237-162356       c
            2204-2365           AC112956.12        159510-159671       c
            2366-2422           AC112956.12        151842-151898       c
            2423-2559           AC112956.12        119492-119628       c
            2560-3368           AC112956.12        100793-101601       c
FEATURES             Location/Qualifiers
     source          1..3368
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 29.12 cM"
     gene            1..3368
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
                     /note="DEAD box helicase 10"
                     /db_xref="GeneID:77591"
                     /db_xref="MGI:MGI:1924841"
     exon            1..295
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             110..2737
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
                     /EC_number="3.6.4.13"
                     /note="DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 10
                     (RNA helicase); DEAD box protein 10; DEAD
                     (Asp-Glu-Ala-Asp) box polypeptide 10"
                     /codon_start=1
                     /product="probable ATP-dependent RNA helicase DDX10"
                     /protein_id="NP_084212.2"
                     /db_xref="CCDS:CCDS52796.1"
                     /db_xref="GeneID:77591"
                     /db_xref="MGI:MGI:1924841"
                     /translation="MGKTVASLGQGTRPDPVRSFNRWKKKHSHRQHQKKERRKQLKKP
                     EWQVEREGISRLMQNYEKINVNEITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGL
                     ALQGKDVLGAAKTGSGKTLAFLVPVLEALYRLQWTSTDGLGVLIISPTRELAYQTFEV
                     LRKVGKNHDFSAGLIIGGKDLKHEAERINNINILVCTPGRLLQHMDETICFHATNLQM
                     LVLDEADRILDMGFADTMNAIIENLPKKRQTLLFSATQTKSVKDLARLSLKDPEYVWV
                     HEKAKYSTPATLEQNYIICELHQKISVLFSFLRSHLKKKSIVFFSSCKEVQYLYRVFC
                     RLRPGISILALHGRQQQMRRMEVYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDC
                     PEDANTYIHRAGRTARYKEDGEALLILLPSEEQGMVQQLLQKKVPVKEIKINPEKLID
                     VQKKLESFLAQDQDLKERAQRCFVSYIRSVYLMKDKEVFNVSKLPITEYALSLGLAVA
                     PRIRFLQKLEKQPSTELVKNPVTEAVPPRAPSLPNDEADESPAYVSEKMSVLHKSGER
                     LEETEHRLASGDGDEEQDEETEDEETEDHLGKAREPHTESVVSIEEAQKVKEVSVQFL
                     NRDDDDEDGPDADFLTVKRRDVFGLDLKENEALSKKEPSKSSVKKKLTKVAEAKKVMK
                     RSFKVNKKITFTDEGELVQQWPQIQKCAIKDVEEEDDTGGINLDKAKERLQEEDKFDK
                     EEYRKKIKAKHRERRLKEREARREANKRQAKARDEEEAFLDWSDEDDGGFDPSTLPDP
                     DKHRSSEESESEDTNHKMSDTKKKQETRKRNNTEDDDVRPRSRHGKKAKWETVEPLDT
                     GLSLAEDEELVLHLLKSQN"
     exon            296..356
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            357..487
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            488..646
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            647..767
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            768..957
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            958..1084
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1085..1247
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1248..1332
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1333..1434
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1435..1522
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1523..1611
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1612..2083
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2084..2203
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2204..2365
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2366..2422
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2423..2559
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2560..3368
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3166..3171
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3187
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
                     /note="major polyA site"
     regulatory      3246..3251
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      3246
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
     polyA_site      3270
                     /gene="Ddx10"
                     /gene_synonym="4632415A01Rik"
ORIGIN      
        1 gtgcgcccct gcgccttctc cacacgctgg tttcgcgtct tccgtgctgt gccttgagga
       61 gcgaggaggc tcccgtgtag cggcgtcgtg ggtcctggca gcccccgcca tgggcaaaac
      121 ggttgcttct ctgggtcagg gaacccgacc cgacccggtg cggagcttta atcgctggaa
      181 gaaaaaacac agccacaggc agcaccaaaa gaaggagcgg aggaagcagc taaagaagcc
      241 ggaatggcag gtcgagcgcg aggggatcag ccgcctcatg caaaactacg agaagataaa
      301 tgtaaatgaa attacaagat tttcagattt ccctttgtcc aaaaaaacat tgaaaggttt
      361 gcaagaagca cagtaccgct tggtaacaga gatacagaag cagaccatag ggttggcttt
      421 gcaaggtaaa gatgtgcttg gtgctgccaa aactggatct ggcaagactt tggcttttct
      481 tgttccggtg ttggaagcct tataccgcct gcagtggact tcaacagatg gcctgggagt
      541 tctgataata tcacctactc gagaactggc ctatcagaca tttgaggttc tacgcaaagt
      601 agggaagaat catgattttt cagctggtct catcattggt gggaaggatc tgaaacatga
      661 agctgagagg atcaacaaca taaacatact ggtttgcaca ccaggtcgac ttcttcaaca
      721 catggatgaa acaatatgtt ttcatgccac caatcttcag atgttagttc ttgatgaggc
      781 agatagaatc ttggatatgg gctttgctga taccatgaat gctattattg aaaatcttcc
      841 caagaaacgc cagactttac tgttctcagc cacacagacc aaatctgtaa aggaccttgc
      901 gcgcttgagt ttgaaagacc ctgagtatgt ctgggttcat gaaaaagcaa aatacagcac
      961 ccctgctacg ttggaacaga actatataat ttgtgagctg caccaaaaaa taagtgtgct
     1021 gttttccttt ttgagaagcc acctaaagaa gaagagtatt gtgtttttct ccagttgcaa
     1081 agaggttcag tatctgtata gggtgttctg caggctgcgc ccagggatct cgatccttgc
     1141 tctccatggc cggcagcagc agatgagaag aatggaggtc tacaatgaat ttgtccgaaa
     1201 gagggccgca gtactttttg ccactgatat tgcagctagg ggactggatt ttccagctgt
     1261 gaattgggtc cttcagtttg attgtccaga ggatgccaac acgtatattc acagagctgg
     1321 tagaactgcc aggtacaaag aagatggaga agcgttatta attttactac cttcagaaga
     1381 gcaaggaatg gtgcagcagc ttctccagaa gaaagtacct gtgaaggaga tcaaaatcaa
     1441 tccagaaaaa cttattgatg ttcagaaaaa attagaatca tttttagctc aagatcaaga
     1501 tttaaaagaa agagctcaaa ggtgttttgt ctcctatata cgctcagtat atcttatgaa
     1561 ggataaagaa gtatttaatg tgagcaagtt acctattact gaatatgcac tgtctcttgg
     1621 tcttgctgtg gcaccgcgga taagatttct tcagaaactg gagaagcagc ccagcacaga
     1681 attggtaaag aatccagtca cagaagcagt tccgcccagg gccccctccc tccccaacga
     1741 tgaagcagac gaatctccag cttatgtcag tgagaagatg tccgtccttc acaaaagtgg
     1801 ggaaagactg gaagagacag aacacagact ggctagtggt gacggtgacg aagaacagga
     1861 tgaagagacg gaagacgaag agacggaaga tcatctggga aaagcaagag agcctcacac
     1921 tgaatctgtt gtcagtattg aggaggcaca gaaggtcaag gaagtttctg tgcagttctt
     1981 aaacagagat gatgatgatg aagatggacc tgatgctgac ttcctcacag tgaagcggcg
     2041 ggatgtgttt gggttggatc ttaaagagaa tgaagcactg tcgaaaaaag aaccttctaa
     2101 atccagtgtc aagaaaaaat taaccaaagt tgcagaagca aaaaaagtaa tgaaaagaag
     2161 ttttaaagtg aacaagaaaa taacatttac tgatgaaggg gagttggttc agcagtggcc
     2221 acagattcag aaatgtgcta taaaagatgt ggaggaagaa gatgacactg gtggtatcaa
     2281 cctagacaaa gcaaaggaaa ggcttcagga agaggacaaa tttgacaaag aagaatacag
     2341 gaagaaaatt aaggcaaagc accgggaaag acggctaaaa gaaagagagg ccagaagaga
     2401 agccaacaaa agacaagcaa aggccagaga tgaagaggaa gcctttctgg actggagtga
     2461 tgaagatgat ggtgggtttg atccaagtac acttccagat cctgacaagc acagaagttc
     2521 tgaagagtcg gagagtgaag atacaaacca taagatgagt gacaccaaga agaagcagga
     2581 aacaaggaag agaaacaaca ctgaagacga tgatgtaaga ccaagaagtc gtcatggaaa
     2641 gaaggccaag tgggaaacgg tagaaccttt ggatacaggc ctgtctttag cagaggatga
     2701 agagctggtg ttacatctcc tcaaaagtca aaactagaca ttctctgtgc cttcctgtac
     2761 tttgatacct ctggatatta ctatgtgggc aagaaattga aaacagcttt ggaaaacagt
     2821 tttgagtttt gaaacatcaa ggaacgtact cagaataagg acgtattgta tactgttaga
     2881 atttatgtat aggttcttat tccccaccat tggaaatgct tgttttgttt attttcacac
     2941 tgttgaagat taaaccaagg ccttgtacat ggtaaataag agctctactc ctgagctgtg
     3001 tacctagtcc ttgcttgttt gttttacagg caaggttctg gatctgttgt tcatttgtta
     3061 ttgttaagta tacataataa ttttatgtat atttcattat ctccaaagaa agagtataat
     3121 agactagccc tgacaaagaa ttttttttaa ttgagttcat aaaaaaataa acttatttct
     3181 tacaaaatac tattgttttt attgtatcca gtgatatgaa agacactcaa agatagattc
     3241 ataaaattaa aacgtgacaa attcctaaaa caagtttttt gtattgttaa ttagcctgct
     3301 caaatgtaac acatcacact cacatttgga gattgctggc aattatttat aaaatctcta
     3361 gacatctg
//
