LOCUS       NM_027942               1520 bp    mRNA    linear   ROD 06-NOV-2024
DEFINITION  Mus musculus DNA-damage inducible 1 (Ddi1), mRNA.
ACCESSION   NM_027942 XM_885770 XM_904138
VERSION     NM_027942.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1520)
  AUTHORS   Nedomova,M., Haberecht-Muller,S., Moller,S., Venz,S.,
            Prochazkova,M., Prochazka,J., Sedlak,F., Chawengsaksophak,K.,
            Hammer,E., Kasparek,P., Adamek,M., Sedlacek,R., Konvalinka,J.,
            Kruger,E. and Grantz Saskova,K.
  TITLE     DDI2 protease controls embryonic development and inflammation via
            TCF11/NRF1
  JOURNAL   iScience 27 (10), 110893 (2024)
   PUBMED   39328932
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1520)
  AUTHORS   Yousaf,A., Wu,Y., Khan,R., Shah,W., Khan,I., Shi,Q. and Jiang,X.
  TITLE     Normal spermatogenesis and fertility in Ddi1 (DNA damage inducible
            1) mutant mice
  JOURNAL   Reprod Biol 20 (4), 520-524 (2020)
   PUBMED   33092996
  REMARK    GeneRIF: Normal spermatogenesis and fertility in Ddi1 (DNA damage
            inducible 1) mutant mice.
REFERENCE   3  (bases 1 to 1520)
  AUTHORS   Ramirez,J., Lectez,B., Osinalde,N., Siva,M., Elu,N., Aloria,K.,
            Prochazkova,M., Perez,C., Martinez-Hernandez,J., Barrio,R.,
            Saskova,K.G., Arizmendi,J.M. and Mayor,U.
  TITLE     Quantitative proteomics reveals neuronal ubiquitination of
            Rngo/Ddi1 and several proteasomal subunits by Ube3a, accounting for
            the complexity of Angelman syndrome
  JOURNAL   Hum Mol Genet 27 (11), 1955-1971 (2018)
   PUBMED   29788202
  REMARK    GeneRIF: The novel observation that DDI1 is expressed in the
            developing mice brain, with a significant peak at E16.5, strongly
            suggests that DDI1 has biological functions not yet described that
            could be of relevance for Angelman syndrome clinical research.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK005882.1.
            
            On or before Jul 25, 2007 this sequence version replaced
            XM_904138.2, XM_885770.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK005882.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1520              AK005882.1         3-1522
FEATURES             Location/Qualifiers
     source          1..1520
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 2.46 cM"
     gene            1..1520
                     /gene="Ddi1"
                     /gene_synonym="1700011N24Rik"
                     /note="DNA-damage inducible 1"
                     /db_xref="GeneID:71829"
                     /db_xref="MGI:MGI:1919079"
     exon            1..1520
                     /gene="Ddi1"
                     /gene_synonym="1700011N24Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             181..1407
                     /gene="Ddi1"
                     /gene_synonym="1700011N24Rik"
                     /note="DDI1, DNA-damage inducible 1, homolog 1"
                     /codon_start=1
                     /product="protein DDI1 homolog 1"
                     /protein_id="NP_082218.1"
                     /db_xref="CCDS:CCDS40527.1"
                     /db_xref="GeneID:71829"
                     /db_xref="MGI:MGI:1919079"
                     /translation="MLITVYCVRRDLTEVTFSLQVNPDFELSNFRVLCELESGVPAEE
                     AQIVYMEQLLTDDHCSLGSYGLKDGDMVVLLQKDNVGLRTPGRTPNHPRADFTGSGSA
                     VPGTSSSRHPHQHQHHYHHHQRIPSTQQAHGLASGENMTFAQELDSPALIRSMLLSNP
                     HDLSLLKERNPALAEALLSGNLETFSQVLMEQQRERTLREQEMFRLYSTNPFDQETQA
                     RIEEEIRQQNIEENMNIAMEEAPESFGQVAMLYINCKVNGHPLKAFVDSGAQMTIMSQ
                     ACAERCNIMRLVDRRWGGVAKGVGTQRIMGRVHLAQIQIEGDFLQCSFSILEEQPMDI
                     LLGLDMLRRHQCSIDLKKNVLVIGTTGSQTHFLPEGELPLCAKLLSGTVQEESSDREV
                     GGTIKHPVKGPGRKKH"
     polyA_site      1520
                     /gene="Ddi1"
                     /gene_synonym="1700011N24Rik"
                     /note="putative"
ORIGIN      
        1 tggggcatca gctggctctg ggtttaggag gcagccccca ctctgtcttg cctttctgcg
       61 agctgaatga gtttcacaca aaggtgtgag gggcaggcca aacatccacc caaaccagca
      121 ccaatcagcc agtgatccac cagatgtttt ctgccaatgt ggcctccctg agcataaacc
      181 atgctgatca ctgtgtattg tgtgcgtagg gacctcacag aggtaacctt ttccctccag
      241 gtcaaccctg actttgagct ctcaaacttc agagtcctct gtgagcttga gtctggtgtg
      301 cctgctgagg aggcccagat cgtttacatg gaacagctcc tcacagatga ccactgctcc
      361 ctgggctcct atggactcaa agatggtgac atggttgtac ttcttcagaa ggataatgtt
      421 ggacttcgga ctccaggaag gactccaaac catcctcgag cagatttcac tgggtctggg
      481 tcggccgtgc ctggaacatc aagttcccga cacccgcatc agcatcaaca ccattatcac
      541 catcatcaac gtataccatc aacacagcaa gcccacggat tagcctctgg agagaatatg
      601 acctttgctc aggaactcga cagccctgcc ctgattcgaa gcatgctgct ttccaacccc
      661 catgatctgt ccctgttgaa ggaacggaat cctgctttgg ctgaagctct gcttagtgga
      721 aaccttgaga cattttctca ggtcctgatg gagcagcaga gagaaaggac cttgagagag
      781 caagagatgt ttcgtcttta ctctactaac ccatttgatc aggaaactca ggctagaata
      841 gaagaagaaa tccgacaaca gaatattgaa gaaaatatga acatagctat ggaagaggct
      901 ccggagagtt ttggacaagt cgctatgctc tatattaact gcaaagtgaa tgggcatcct
      961 ttaaaggctt ttgttgactc tggtgcccag atgactatca tgagccaagc ttgtgctgag
     1021 agatgtaata ttatgagact ggtagaccga cggtggggtg gggttgctaa gggagtaggc
     1081 acacagagga ttatgggccg cgttcatctg gctcagattc aaattgaagg tgatttctta
     1141 cagtgctctt tctctatact tgaagagcag cccatggata tccttctagg gcttgatatg
     1201 ctcaggaggc accagtgttc catcgaccta aagaaaaatg tgctggtgat tggcactacc
     1261 ggctcacaga ctcacttcct tcctgaagga gagttgccct tgtgtgctaa actgttgagt
     1321 ggaactgtac aagaagagtc ttcagacagg gaagtaggag gtactatcaa acaccctgtc
     1381 aagggtcctg gacgtaaaaa gcattgaagg aggtcttaca taattatgcc actgccacaa
     1441 ggaaacaaag cctcaggctt caggaaatta taagacatga gctcactggc aaagtcatca
     1501 ttaaaaacaa tttagcaacc
//
