LOCUS       NM_001110223            9000 bp    mRNA    linear   ROD 25-FEB-2025
DEFINITION  Mus musculus doublecortin (Dcx), transcript variant 2, mRNA.
ACCESSION   NM_001110223
VERSION     NM_001110223.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 9000)
  AUTHORS   Kawase,K., Nakamura,Y., Wolbeck,L., Takemura,S., Zaitsu,K.,
            Ando,T., Jinnou,H., Sawada,M., Nakajima,C., Rydbirk,R., Gokenya,S.,
            Ito,A., Fujiyama,H., Saito,A., Iguchi,A., Kratimenos,P.,
            Ishibashi,N., Gallo,V., Iwata,O., Saitoh,S., Khodosevich,K. and
            Sawamoto,K.
  TITLE     Significance of birth in the maintenance of quiescent neural stem
            cells
  JOURNAL   Sci Adv 11 (4), eadn6377 (2025)
   PUBMED   39841848
REFERENCE   2  (bases 1 to 9000)
  AUTHORS   Tang,I., Nisal,A., Reed,A., Ware,T.B., Johansen,A., Zaki,M.S.,
            Cravatt,B.F. and Gleeson,J.G.
  TITLE     Lipidomic profiling of mouse brain and human neuron cultures
            reveals a role for Mboat7 in mTOR-dependent neuronal migration
  JOURNAL   Sci Transl Med 17 (779), eadp5247 (2025)
   PUBMED   39742503
REFERENCE   3  (bases 1 to 9000)
  AUTHORS   Wang,W., Yin,C., Wen,S., Liu,Z., Wang,B., Zeng,B., Sun,L., Zhou,X.,
            Zhong,S., Zhang,J., Ma,W., Wu,Q. and Wang,X.
  TITLE     DCX knockout ferret reveals a neurogenic mechanism in cortical
            development
  JOURNAL   Cell Rep 43 (8), 114508 (2024)
   PUBMED   39018244
REFERENCE   4  (bases 1 to 9000)
  AUTHORS   Ma,Q., Yang,Z., Yang,C., Lin,M., Gong,M., Deng,P., He,M., Lu,Y.,
            Zhang,K., Pi,H., Qu,M., Yu,Z., Zhou,Z. and Chen,C.
  TITLE     A single-cell transcriptomic landscape of cadmium-hindered brain
            development in mice
  JOURNAL   Commun Biol 7 (1), 997 (2024)
   PUBMED   39147853
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 9000)
  AUTHORS   Wang,K., Liu,X.Y., Liu,S.F., Wang,X.X., Wei,Y.H., Zhu,J.R., Liu,J.,
            Xu,X.Q. and Wen,L.
  TITLE     Rbm24/Notch1 signaling regulates adult neurogenesis in the
            subventricular zone and mediates Parkinson-associated olfactory
            dysfunction
  JOURNAL   Theranostics 14 (11), 4499-4518 (2024)
   PUBMED   39113792
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 9000)
  AUTHORS   Matsuo,N., Kawamoto,S., Matsubara,K. and Okubo,K.
  TITLE     Cloning and developmental expression of the murine homolog of
            doublecortin
  JOURNAL   Biochem Biophys Res Commun 252 (3), 571-576 (1998)
   PUBMED   9837748
REFERENCE   7  (bases 1 to 9000)
  AUTHORS   Sossey-Alaoui,K., Hartung,A.J., Guerrini,R., Manchester,D.K.,
            Posar,A., Puche-Mira,A., Andermann,E., Dobyns,W.B. and
            Srivastava,A.K.
  TITLE     Human doublecortin (DCX) and the homologous gene in mouse encode a
            putative Ca2+-dependent signaling protein which is mutated in human
            X-linked neuronal migration defects
  JOURNAL   Hum Mol Genet 7 (8), 1327-1332 (1998)
   PUBMED   9668176
REFERENCE   8  (bases 1 to 9000)
  AUTHORS   Gleeson,J.G., Allen,K.M., Fox,J.W., Lamperti,E.D., Berkovic,S.,
            Scheffer,I., Cooper,E.C., Dobyns,W.B., Minnerath,S.R., Ross,M.E.
            and Walsh,C.A.
  TITLE     Doublecortin, a brain-specific gene mutated in human X-linked
            lissencephaly and double cortex syndrome, encodes a putative
            signaling protein
  JOURNAL   Cell 92 (1), 63-72 (1998)
   PUBMED   9489700
REFERENCE   9  (bases 1 to 9000)
  AUTHORS   Omori,Y., Suzuki,M., Ozaki,K., Harada,Y., Nakamura,Y., Takahashi,E.
            and Fujiwara,T.
  TITLE     Expression and chromosomal localization of KIAA0369, a putative
            kinase structurally related to Doublecortin
  JOURNAL   J Hum Genet 43 (3), 169-177 (1998)
   PUBMED   9747029
REFERENCE   10 (bases 1 to 9000)
  AUTHORS   Wolff,G.L., Greenman,D.L., Frigeri,L.G., Morrissey,R.L., Suber,R.L.
            and Felton,R.P.
  TITLE     Diabetogenic response to streptozotocin varies among obese yellow
            and among lean agouti (BALB/c x VY)F1 hybrid mice
  JOURNAL   Proc Soc Exp Biol Med 193 (2), 155-163 (1990)
   PUBMED   2137249
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AB011678.1, BC056391.1 and
            AK164139.1.
            
            Summary: This gene encodes a member of the doublecortin family. The
            protein encoded by this gene is a cytoplasmic protein and contains
            two doublecortin domains, which bind microtubules. In the
            developing cortex, cortical neurons must migrate over long
            distances to reach the site of their final differentiation. The
            encoded protein appears to direct neuronal migration by regulating
            the organization and stability of microtubules. In addition, the
            encoded protein interacts with LIS1, the regulatory gamma subunit
            of platelet activating factor acetylhydrolase. Studies in knockout
            mice lacking this gene and the LIS1 gene suggest that the molecular
            interaction of these two genes is important in both in neuronal
            migration and neurogenesis, and there is a cortical role of this
            gene in nuclear translocation and positioning of the mitotic
            spindle in radial glial mitotic division. Multiple transcript
            variants encoding three different isoforms have been found for this
            gene. [provided by RefSeq, Sep 2010].
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Both variants 1 and 2 encode the same isoform (a).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB011678.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2246              AB011678.1         97-2342
            2247-4113           BC056391.1         2138-4004
            4114-5814           AK164139.1         671-2371
            5815-7411           AK164139.1         2374-3970
            7412-9000           AB011678.1         7525-9113
FEATURES             Location/Qualifiers
     source          1..9000
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 64.89 cM"
     gene            1..9000
                     /gene="Dcx"
                     /gene_synonym="Dbct"
                     /note="doublecortin"
                     /db_xref="GeneID:13193"
                     /db_xref="MGI:MGI:1277171"
     exon            1..150
                     /gene="Dcx"
                     /gene_synonym="Dbct"
                     /inference="alignment:Splign:2.1.0"
     exon            151..536
                     /gene="Dcx"
                     /gene_synonym="Dbct"
                     /inference="alignment:Splign:2.1.0"
     CDS             173..1273
                     /gene="Dcx"
                     /gene_synonym="Dbct"
                     /note="isoform a is encoded by transcript variant 2;
                     neuronal migration protein doublecortin; lis-X; doublin;
                     lissencephalin-X; doublecortex; lissencephaly, X-linked
                     (doublecortin)"
                     /codon_start=1
                     /product="neuronal migration protein doublecortin isoform
                     a"
                     /protein_id="NP_001103693.1"
                     /db_xref="CCDS:CCDS53209.1"
                     /db_xref="GeneID:13193"
                     /db_xref="MGI:MGI:1277171"
                     /translation="MELDFGHFDERDKASRNMRGSRMNGLPSPTHSAHCSFYRTRTLQ
                     ALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVR
                     YIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQ
                     SLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAI
                     KLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKG
                     NPSAAAGPKASPTPQKTSAKSPGPMRRSKSPADSGNDQDANGTSSSQLSTPKSKQSPI
                     STPTSPGSLRKHKVDLYLPLSLDDSDSLGDSM"
     exon            537..877
                     /gene="Dcx"
                     /gene_synonym="Dbct"
                     /inference="alignment:Splign:2.1.0"
     exon            878..980
                     /gene="Dcx"
                     /gene_synonym="Dbct"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1118
                     /gene="Dcx"
                     /gene_synonym="Dbct"
                     /inference="alignment:Splign:2.1.0"
     exon            1119..1216
                     /gene="Dcx"
                     /gene_synonym="Dbct"
                     /inference="alignment:Splign:2.1.0"
     exon            1217..8982
                     /gene="Dcx"
                     /gene_synonym="Dbct"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8963..8968
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dcx"
                     /gene_synonym="Dbct"
                     /note="hexamer: AATAAA"
     polyA_site      8982
                     /gene="Dcx"
                     /gene_synonym="Dbct"
                     /note="major polyA site"
ORIGIN      
        1 agttacaggg gagaagctgg acaaggcact aggacctaga aggcaactat ccaccctggc
       61 aggaatttct tgcttggagc tcagacaaca aaggcataga gagattggtt ttctttctct
      121 cagcatctcc acccaaccag cagaaaaccg gttgctgtgg ttccaccaaa atatggaact
      181 tgattttgga cattttgacg aacgagacaa agcatctaga aatatgagag ggtcacggat
      241 gaatggactt ccaagtccca ctcatagtgc ccactgtagc ttctacagaa ccagaacctt
      301 gcaggcatta agtaatgaga agaaggccaa gaaggtacgt ttctaccgca atggggaccg
      361 ttacttcaag gggattgtgt acgctgtttc ttctgaccgt tttcgtagtt ttgatgcgtt
      421 gctggctgac ctgacccgat ccttgtctga caacattaac ctgcctcagg gagtgcgcta
      481 catttatacc attgacggat ccaggaagat tggaagcatg gatgaactgg aagaagggga
      541 aagctatgtc tgctcctcag acaacttctt taaaaaggtt gagtacacca agaatgtcaa
      601 ccccaactgg tctgtcaacg taaagacatc tgccaacatg aaagcccccc agtccttggc
      661 tagcagcaac agtgctcaag ccagagagaa caaggacttt gtgcgcccca aacttgtgac
      721 catcattcgc agcggggtga agccacggaa ggctgtgcgc gtgcttctca acaagaaaac
      781 agcccactct ttcgagcagg tcctgactga catcacagaa gcgatcaaac tggaaaccgg
      841 agttgtcaaa aaactctaca cccttgatgg aaagcaggtc acctgtctcc atgatttctt
      901 tggtgatgat gatgtgttca ttgcttgtgg tcctgaaaaa ttccgctatg ctcaagatga
      961 tttctccttg gatgagaatg aatgcagagt catgaaaggg aatccatctg ccgcagctgg
     1021 cccaaaggct tccccaacac ctcaaaagac atctgctaaa agcccaggcc caatgcgccg
     1081 cagcaagtct ccagctgact caggtaacga ccaagacgca aatggaactt ccagcagtca
     1141 gctctcaaca cctaagtcaa agcagtctcc tatctctaca cccacaagcc ctggaagtct
     1201 gcggaagcac aaggtagacc tgtacctgcc gctgtcattg gatgactctg attcacttgg
     1261 cgattccatg tgaaagatga taggctaaat caaagcctat tattgtagca gaatactttc
     1321 gctcaagtga ccaacaaggc tattggtgct taaacatttt tgttattgtt gcttttcaaa
     1381 acactctgta gtatgtaggg tttattttct tgtgacttct cttctgggcc actaattcac
     1441 atttaccaat aagagataga ttgataacca tccttttgag tgacttttcc agaacttcaa
     1501 agtgtgctac tccatgacct ttctactgaa tgcttagggg cctttgtatt ttccccactc
     1561 aatttgttca gaaactagtc ttccttctct ggaaggctgt ttacatacac atcacttaaa
     1621 atgtttatgt gtggggaaaa ctttcatatg cagatctaaa agcgaaaaac ctaagtgtcc
     1681 cttgcctctg tatcttcaga atgctggagg atctcaggag agtggcaagt cagatccttg
     1741 gtctcactct ttgctcttaa ttgagccccc agtgtattgt ctagcattca tcctggctgt
     1801 tgagatggag aaacaccagc gacttttgat gtgacaccat gtgcttaggg ctgtggtata
     1861 gggctgtctg aaagatatga ggtagaatat agggggaaaa ctgcccaaat ttcagtagga
     1921 tttgtataaa gcacagtgga ttcctggtta acccctctac tggggaaatt tggaatcaat
     1981 caattgatta gtttggggta catgatgtca catacatgat ccttccagga ggctttctaa
     2041 tgtacaagtt agtacatgaa cggtatggta tccatctagc tctgttctat tgaatgcctt
     2101 gtaaacaacc aacactacaa acactgtgag aatttgtttt caggtctgac accttttggt
     2161 cgctttttat agcaagaaac catatccttt tttataaaaa actcaactct gtatttcagg
     2221 agcaaaactc ttcaggctcc ttttttataa gctggtgatt tttttccttt gtctaaaaaa
     2281 cacaagtaga aaattgacca aaaaaatgca gaagaatact gtagtttaga aatcatgctc
     2341 tcactgccaa acagaaagct ccgggagaaa acacaatgac tagaggccaa ttcaatagaa
     2401 tcaggttttt gatacctttt taacagttac acttacagta ataatttcaa tgtggaccag
     2461 acattctagt tatattttaa atgaaatgtt atggcatatt ttaagtaact cttttttatc
     2521 tataatccta atatttcata cttaagatgc agaaaccttt cacttgactt taacattagg
     2581 aaggacttct ctttattacg gattgatcac ttgaaataac tctgtctttg aggtacaggt
     2641 ttataacatt gctttttctc tgtattcata gcccataata gccaagacaa cgaaagttag
     2701 gtgaaagcca tgcatgccaa ttctgtgttt gatttgacga gataggaaga tttccttcac
     2761 ttctttgtaa ttgttcagat agtttgaaag atgcagcatt caaagtttgg ctgctgaatg
     2821 acatgcagtt gtccctccat tctaagtaga atgagtgtgg ggttcatttg tgtgtgtgtg
     2881 tgtgtgtgtg tgtgtgtgtg tgtgtgtgct cgcgcgcgca tgcgcaagca cgcctaggct
     2941 gcttcatact tagcaaatac tgcacaagac aactcaacat gaattgatga caacttggtg
     3001 gcattgctga tgtgcagggg gaagtaggat ggcaggggta cctagagccc ccttgataaa
     3061 tttcagatgt ccttaattat gagattccaa gaaacatttt tgcttttggt tcagcagaag
     3121 ggggatgatg agagctctgg tttctgctta cactgctcat tgaagagccc aaaatcatga
     3181 ggttttgctc cccccccctt tattgctatg cccacatgaa atgattaaga aacccatttt
     3241 aatcggcccc tatttttttt tctacaagct cagtgatttc ttagtgcctc ccagaacatt
     3301 tgagttaatt agggaaaatt ggttatttgg gatggataga aattgtggta ggagatctat
     3361 ttttaacctc tgggccagat cctccagcac actctatgtt gttctttgag caaatcccat
     3421 gttgtcccaa gtattcattt aagatgagac atggagattc tactgaaaga gtgggagcaa
     3481 agaaatttca acagtcccta tgcccaggct tcttggtagt tctctgagca tttttctact
     3541 tgtagtataa tatagcacta gaaaatacta tggacatatc ttttttagaa tattcttaga
     3601 acagacattc ttgtataaca acagtgtcct ttctgttttt ctttgtgcta actacaagta
     3661 aacctttaac aaatactttt cctttatata caggcacaga tacatacata taagaaaact
     3721 tttttttact gctacttcgt gtggcaaggg ttggtaaaat tgaaaactca agtctccaat
     3781 aatttagttt taaattggct caaattcaag taattttttt cagaactaag ctcttacatc
     3841 ccccgtattc tttctcagtt tttcctaatc cacttttacc actttagtcc catcaagttc
     3901 agcgtgcatg gtcagcaagc atttgccact attttccata acaccccctc tctctttttc
     3961 cctcctcctc cctccttctc tctctctctc tctctctctc tctctctctc tctcacacac
     4021 acacacacac acacacacaa agaatatgtt gcttgttcct acctcctgac tgttcttccc
     4081 cacagaaata gaaatagggg caaaaaaaaa aaagggaaat gtatatatag gggctgggtt
     4141 gaacaactaa cttcgtaagt agtgctaagt ataattaaag tgagagaaaa gctccttttc
     4201 tcataattgt tttggaaagg atagccatta gcatgactgc tttgtgtcct tgtggacttt
     4261 agtattagcc tagactgaat tatagcattt tctagctgga aagaggatta agatctcatc
     4321 atctgctccc aatttttcat tttcttaagg ccaggaaaca gacaaagaca taaagtgatt
     4381 tccccctaag gtcacacagc tgcccattgg cagtgctggg attagaacct acacctcttg
     4441 gctcttattc caattttttt cccccaacta gtgagtattg tcctttgtga ggctcctgca
     4501 aattctttcc cagggtcatg ttgcaccctg gatccatatg ctactttgtt ggtctcagca
     4561 agaaatccac acagcaatat aatctggccc ttcctcctca ctttcacatt acttcatcca
     4621 catggcctgc agacagttcc aaggagaggg aggcattgag acgttgagca ccagagggtt
     4681 gctgccctac cttgaggaat cttccaaata gctcgctgaa ctccactcta ttcatggaga
     4741 atggaaaatg actactttgt cccttatcag cttccttcaa ggtcatgtca cacgtgttcc
     4801 tcccaggata ggggagtgat ttccagagca cagaaaatta gaagtgaata acagagtaat
     4861 agctttgttt attctgactt tctaaagatg actttttttt agccatttaa aaaattagtc
     4921 tggctatctt tactactaat aacaatttcc tttaaaatat ggcagtgagc caagccagag
     4981 aaagataatc aagtcttgtg tttatcctca atctctacgc ccttgtagcc atgctccctg
     5041 gtacaaacaa ttttcaggta taaacaagtg tcttttgtca ctaaattgtg ccctggctga
     5101 cactgaatat ttgtatctat accaaaaata gcatacagtg accttacaca ttatattctc
     5161 tctctctctc tctctctctc tctctctctc tctctctctc tctgtgtagc ctgtttctgt
     5221 gctttccatg acagaagtta gggcaacatg atctgtatgt gtaggtttct ttgcagcaag
     5281 gctttcctgg aactaatgaa tattcactga attctagaag atctcttact aaatttaccc
     5341 aagttcagga acttctctat cttttcttcc ctccatctgg gagtgaccaa ggaattgtaa
     5401 agtgggtagg tagcttccat gtcctagaat catcaagcct aagttgaagg caaatgactc
     5461 aatgcttgat ttgcataaac ttgtgtcccc atgcccagtc tctccaatag tctacataga
     5521 gatttcccca tttcctctca catttgactc caaatggatt tttcctttag aaaacaggga
     5581 aggaaataag ccctatctcc ttagaatggg agcgatcaca cacccatggg tccccaatga
     5641 gcttctgtga tggtgagaat gttgcaagag atgagactgc cttgggaaca gttgtatcaa
     5701 gagacttctc tagcagaaac ccaatgacag catagcttta cggacttcct tcatggtcta
     5761 gtttgctatg gaaatagaaa acataggatc tttctctttt ctttcttttt ttttcttctt
     5821 tttgaaacaa tgcttggatc ctgttcttgg gcacatgggg ccatttggac ccatacctag
     5881 gcctcagtta tatattgcct tcattatatt aagacgttta ggcttctagg ctcaaattag
     5941 ttttctaaac agagcaaggg tactttggag ctcatatggg tgcacaggaa ggcctatgtc
     6001 ctatgattta gatctggaac catgggatgg taaaggctgt atagtgacct agtcatttag
     6061 agtatgtcag gtataatgtg ttagaagctc atgcttctgc ctctgccctt ctaaaaccac
     6121 gtgtgtcgtg ccactcactg ttacgtgaat cctgaaggat ttcctcttct ttcaaacatg
     6181 accacctgga gcaagaatag gtcactgact ttttgtgctt tctttttgat tagagagacc
     6241 tctatctccc ttggatgcat aaatgaagtt tcattagcca tcacaccaag ggcttcttag
     6301 tgttgattaa tgtggagctc atgttttggc caaactggtg tgagattggc tatcattggg
     6361 aagtgaagta tttcttaact ttactggagt caaaaatctt ctgaaattag aagtgatttt
     6421 tttttctatc tggcatacct ggggctaggg aagtagagaa ttctcagttg aaagtaaggc
     6481 actttcctac ttggattaca agagcagttg agttgaaaaa ggtcaaagag aacagagaag
     6541 tcagaagacc aagtcttgta aactaaaaca aagacccgaa gcttcagaat gtctcgattt
     6601 tgggcaataa ctcaaggaaa taaatggctt tttgtcattc catttcctgt tttctttctc
     6661 tatttagatg cctatatttg ttctcagtta tcagtctctc attcggtagc aaaaacatcc
     6721 attctttgac ttgtgaggta cttcctcctc ttttggaatc cgttgcttct tcccacctca
     6781 ctactgggta taagcttctt catagtctgt aagttttacc ttgggattga agagaaatta
     6841 ttttctgttt caaaaattcc tggttctacc cctgttcagt cacaagtagg ttggtagaaa
     6901 acaacctgat tctgaccctt tctttttttt tttcctgttt tagtctcagt agatcttttc
     6961 aagcactgtc cttacagctc atgaatgttt aggtctttat cttctaagca agcattgtac
     7021 agaacacgtt gtgcttcttc tttttgtctg ccattttgtg aacggtgtaa tgtgctcaga
     7081 taaataatca gctgagcagg aaaagagtct actcatctat tcaaattggc aaaccattgt
     7141 ttagtttgta tcattaaatt tgctcatagc ttcgaaaagc tgcaatataa tgtcatgaga
     7201 gaccacaggt aattgttcct gtcatttggt tgggcttagt ggagatgggg gtgggcagga
     7261 acaatttgtt taaactttta acgctattca ttaagctctc tgttataaca ttatgatctg
     7321 tgatcttggc cacctgtcga actgtttaag ctaaactagt gggcaattaa agttaattta
     7381 agtaaaaaat tatctaacaa atccaggcta cagaaaaaaa aaaaaactta gttaaatgta
     7441 tttgtcctta cgatactaga tttacctaaa cattttcctt ttaacaccaa ctgttcacga
     7501 tccaggactg cctgtccatg tatcaataat gagcagtctt aagtctgcta attaattcag
     7561 aaaccttggg gatgtcaatg tcactgcttg gcagtaccat atgcattgcc catttttcca
     7621 gtaacttttc tttctaagtt ctcttaaaga cttttgagaa agtaagaagc taagtgaaca
     7681 tatatccaat gttttgtaat gtattatatt gcagcattaa gtcaacaacc ccttatgacg
     7741 tgtacccagc taatgcatgg tttcagagtg gattttgcat ttttcatgtg cagtaaatga
     7801 tttaaaaatg tttttggtca cctttttgtg ccattaaact tgtacagaaa atgcttttat
     7861 ggccattttc aatgggagaa agttaaaaaa tggaaacagc ccaccctttc tgccctatag
     7921 ctgtagttag aattgagtac atgtagaaat acggctgtaa ttggtggttg tagtgttata
     7981 gttgttagct tgctagtgac tgcctttgga gagtaaatgc atggtcttgt acatcacatt
     8041 tcttaaataa ctcattttaa cctctgaaaa ggatatatta ttccatgtgg ccctcttccc
     8101 tccctccatt ccctgctccc agatatctta ccattaactg taaatacctg atttaggggc
     8161 caagagtttc tgccaagtaa agttagcaag gagcaaataa cccaaaaggg gtgaagagaa
     8221 tttcacaaca atttctcaga agttattgac cctttctcaa ggaatggcat ggttatcaaa
     8281 gactcagctg tcttttacat aaaaatcaga ggcaaattgg gagtgtcttt ggctgccaga
     8341 ttacagaatt gaaaaattct tagaatcata caacccaagg atgtccctga tccctgcatt
     8401 acttgtgagg catttggaga catcagagat ttgctgacta atatttattg gggataaaaa
     8461 gaaaagcaaa acagagatgt gcgacagata ctcaggggtt tcagctaggc tccagtcagc
     8521 aaaggtaagg atgtgggttt agatgcattg ttatctgttt cccaggcaat gcttaacaca
     8581 ctcttagtgc tttgagtgat acaaaggcag tgtttcaaca agacactctc ttctttggtt
     8641 tgctgttctc tcttggactg gaatgtttgg caaggcccat gtaaactggt tagagcaggc
     8701 cctttatatc tcctgtgacc gttaatctcc cccaccataa tttgatgagg gctgtttggt
     8761 ttgaggactt caaggatgtc tagagaagtt cccccatgtg tgtgaggtgt tgtgaactgt
     8821 gaacactgta catcttcagt gttcaatact gggcagccaa agagctgctc ttgcaatctt
     8881 tttttggctc tcaagctctg ttctccatcg aattctcatt tctgtgtaca tttgcaagat
     8941 gtgtgtaatg tcattttcca aaaataaaat ttgatttcaa taaaaaaaaa aaaaaaaaaa
//
