LOCUS       NM_001163703            5618 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus defective in cullin neddylation 1 domain containing 3
            (Dcun1d3), transcript variant 2, mRNA.
ACCESSION   NM_001163703
VERSION     NM_001163703.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5618)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5618)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   3  (bases 1 to 5618)
  AUTHORS   Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
            Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
            McMahon,A.P. and Southard-Smith,E.M.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5618)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC131702.3 and AC122423.2.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Variants 1 and 2 encode the same protein.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK155160.1, BC030335.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-188               AC131702.3         105732-105919
            189-724             AC122423.2         3040-3575
            725-5618            AC122423.2         4899-9792
FEATURES             Location/Qualifiers
     source          1..5618
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 64.27 cM"
     gene            1..5618
                     /gene="Dcun1d3"
                     /gene_synonym="1700020A13Rik; DCNL3; SCCRO3"
                     /note="defective in cullin neddylation 1 domain containing
                     3"
                     /db_xref="GeneID:233805"
                     /db_xref="MGI:MGI:2679003"
     exon            1..188
                     /gene="Dcun1d3"
                     /gene_synonym="1700020A13Rik; DCNL3; SCCRO3"
                     /inference="alignment:Splign:2.1.0"
     exon            189..724
                     /gene="Dcun1d3"
                     /gene_synonym="1700020A13Rik; DCNL3; SCCRO3"
                     /inference="alignment:Splign:2.1.0"
     CDS             294..1208
                     /gene="Dcun1d3"
                     /gene_synonym="1700020A13Rik; DCNL3; SCCRO3"
                     /EC_number="3.1.-.-"
                     /note="DCUN1 domain-containing protein 3; defective in
                     cullin neddylation protein 1-like protein 3; DCN1,
                     defective in cullin neddylation 1, domain containing 3;
                     squamous cell carcinoma-related oncogene 3"
                     /codon_start=1
                     /product="DCN1-like protein 3"
                     /protein_id="NP_001157175.1"
                     /db_xref="CCDS:CCDS21789.1"
                     /db_xref="GeneID:233805"
                     /db_xref="MGI:MGI:2679003"
                     /translation="MGQCVTKCKNPSSTLGSKNGDRDPSNKSHSRRGASHREEQVPPC
                     GKPAGDILVNGTKKAEAATEACQLPTSSGDAGRESKTNAEESSLQRLEELFRRYKDER
                     EDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATMCKFTRKEFFDGCKAISADSID
                     GICARFPSLLTEAKQEDKFKDLYRFTFQFGLDSEEGQRSLHREIAIALWKLVFTQNNP
                     PVLDQWLNFLTENPSGIKGISRDTWNMFLNFTQVIGPDLSNYSEDEAWPSLFDTFVEW
                     EMERRKREVEGRGTLSSGQEGLCPEEQT"
     exon            725..5618
                     /gene="Dcun1d3"
                     /gene_synonym="1700020A13Rik; DCNL3; SCCRO3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2959..2964
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dcun1d3"
                     /gene_synonym="1700020A13Rik; DCNL3; SCCRO3"
                     /note="hexamer: AATAAA"
     polyA_site      2977
                     /gene="Dcun1d3"
                     /gene_synonym="1700020A13Rik; DCNL3; SCCRO3"
     regulatory      5600..5605
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dcun1d3"
                     /gene_synonym="1700020A13Rik; DCNL3; SCCRO3"
                     /note="hexamer: AATAAA"
     polyA_site      5618
                     /gene="Dcun1d3"
                     /gene_synonym="1700020A13Rik; DCNL3; SCCRO3"
                     /note="major polyA site"
ORIGIN      
        1 ggggcttcgg ggcggccgcc gccggtgggc tgcagatgag gaggaggcgg cggccgcggt
       61 ggcagaaaag gcggcggcgg cgggggtagg gagcctggaa acgcaagcgg ggatggtagg
      121 tagtttggac ccgccgggcc gccgtcgttt ccagaaaggg tttgactgga ggaacctctg
      181 gagcagctgt tgcctggctc ctctaactga tggcatgttg aagtacatgg gccagtggca
      241 gcgagggcat ttgatccaga ggggtccact ctagaggcca gggtactacc accatgggcc
      301 agtgtgtcac caagtgcaag aatccttcat caaccttggg cagcaagaat ggagaccggg
      361 accccagcaa caagtcacac agcaggcggg gggctagcca ccgtgaggaa caggtgccac
      421 cttgtggcaa accagctggg gatattcttg tcaatgggac caagaaagca gaggctgcca
      481 ctgaggcctg ccagctgcca acttcttctg gagatgctgg gagggagtcc aagaccaatg
      541 ctgaggagtc ttctttgcag aggttggaag aactattcag gcgctacaag gatgagcggg
      601 aggatgcaat tttggaggaa ggcatggagc gcttttgcaa tgacctatgt gttgatccta
      661 cagaatttcg agtgctgctc ttggcctgga agttccaggc tgctaccatg tgcaaattca
      721 ccaggaagga gttttttgat ggctgtaaag caataagtgc agacagcatt gatgggatct
      781 gtgcacggtt ccctagcctc ttaacagaag ccaaacaaga agataaattc aaggatctct
      841 accggtttac atttcagttt ggcctggact ctgaagaagg gcagcggtca ctgcatcgtg
      901 aaatagccat tgccctatgg aaactagtat ttacacagaa caatcctcca gtattggacc
      961 agtggctaaa tttcctaaca gagaaccctt cgggaatcaa gggcatctcc cgggacactt
     1021 ggaacatgtt tcttaacttc actcaggtga ttggccccga cctcagcaac tacagtgaag
     1081 atgaggcctg gccgagtctc tttgatacct ttgtggagtg ggaaatggag agaaggaaaa
     1141 gagaagtgga agggagaggt acactcagct cagggcaaga gggcttgtgt ccagaagagc
     1201 agacttagcc gctctgttcc aggagcagca ctgaggatct gcctgctgcc ctgcagccaa
     1261 atgaggaatt ggacctttct ggaaattact gaagatccgg atattttcta ctttacacct
     1321 ttctctgcct tgtatttgaa agggctctaa aatgctgtat catgttttag gcactttctt
     1381 catttttttt tttttttgtt attttggtta tttctttttt gggggtggga aatcccccaa
     1441 aatatttgaa cctggctaca tgttgtgtac ctttttttga agccttcaga tagaataagc
     1501 ctgccatttc ttgcacaact tgataggatt tgttttgtgg gggaggggag ggtgtagccc
     1561 gggttgggag tgggttgtta ggttgaatta acattacaaa atgatgcagt gccagacctc
     1621 agttttgcat attatttttc agggcaggtc tgtactgtgt gtagtgctgt ttacatggtt
     1681 gaatttaggt tgtaataatt attttaaaag atttacacag atatgaatat agcagtgtta
     1741 actgttagcc acattgcatt aatttccaga cagtttggag ctcttggaga gccaaggcca
     1801 aggccagtca agagcatttg cagtctgaca ccccaccccg tccctttaag ctaatttatc
     1861 caaagccctg tctccctcac ttcttgctca ttccttcttt gacctattgc atttcatatt
     1921 taacttaccc atcatcatgc tgtacctgtc agtcaagtga gcagttttgt tttgttttgt
     1981 tagaacacat tgtactgaaa accacttaag cattgaatgc agagaaagca gtgctacctc
     2041 agttttgctg gaagtagact tctttgatag ttttctttga tgtttttgta ttttcatgtc
     2101 ataagtggaa atacttcttt ttctcccctt ttcatttgcc ttggagccaa agtttccgtt
     2161 ctgggtggtg agaaaagtgt gcctgccagc cgacctgaaa gaaagcggtg gcatggagct
     2221 ctgcttcaaa ctgttttttc tctagttttg ttgagtatca ttagcttact tgtctggcaa
     2281 gtgcagaagc ctgaggctgg cctgaactct gccaaacaaa ttatccacgt gtattgaatc
     2341 attaaattgt gtgccctctc cctctttgct gcgcccacgt tgtcacttaa cccctaggaa
     2401 ttatttattg tctttttgtt aatgtcaagc tcggttgggg taacgtggtg actgtttagg
     2461 tttacatgac cctcttctct ttcccttacc ccagacatgt atatatacat atataagata
     2521 tgtatatatt ttacctttat aaaatatata tatatacaca tatatgtatc tatatccctt
     2581 tgtttgtctg ctaaaactgg ccatgaaaga gggagctgcc ttcaatctgt agtttaagaa
     2641 gatgccaggg agcatcataa acggaggcta ttgtatatta atttagactt tttcactaaa
     2701 aagaacatga atgaatttgc ttgccgaagg aggaaccagt tctctagact ccatgctcac
     2761 tctacaaggc cagctttggt caagctgcca ctggggcctg aagagctgac tctgtcctac
     2821 cttattccac taaagtacca tcttgataat ttccccttaa aaaatattct caaaaatgta
     2881 ctggaaagtg ggtggcagga gcttgtacag ttcagcttcc aacatttcgg aacagattta
     2941 aaagggaatc ttttaataaa taaaagttac aaaaatattt atactcttga tacaatgaaa
     3001 aagtgtctat taaatatttg gaatttcctc ccttgattag tctaccccaa atcctgggta
     3061 catgtttctc aacctgggta agaattgcat gctttgagtt cttcatgagt cttatagctc
     3121 taggcactta tctttataaa aatgattatt taaggagatg acagtcatat ttcttaaagt
     3181 cggtattgac acagggaaca tttttgtaag cctcacaatt gtccttcctt gagggatgag
     3241 atgatgaata tcagccacag acttacgata gtgctggaag gcccaagtgg ctgttgggcc
     3301 agatgtaccc cttttttttc tagccagaat aagatgaaat ccttgagtaa gaatccagga
     3361 gcccagtagt ttctgagggc acagctacat tataacattt ggttaagatc tcatctagcc
     3421 agttagttgt tcctaattca ggattaggta gaaatctaat gagggaagag gtggagttag
     3481 gtaagacttt ctgtcccaga taagaaaggg tgtatgtggg gaaagtgcca agagggagtt
     3541 tgccaagggc cccatggact caaggaacta gatcttttcc tcattgggta gaggtttttt
     3601 taactgctca gtttctccaa tcccaatgcc tgcaccccaa ccccagccat ttagaaattg
     3661 tgattatatt tttaatcatc tgttgttgag aaaccagaga aaggaacagt attcagggag
     3721 ggactttggg ttttctgtgt agttgctttg ctttgccaag agattctcag tgaggtgtaa
     3781 ggtttgcagt taacacttct gggaaacaaa agtttctgtt tcactcaccc tcagataggc
     3841 ttgctgctta ttgggtggat gagcagtggc tgggagccaa attgctcctc aggttagcta
     3901 gctttgtggc ttcaggtgat ttgggaaggg gtgatatcag ggtgccattt tggaattctg
     3961 caatgtctaa gcattactac acagaccgtt ggaaattgca tactttgggc aaatgacttt
     4021 ttgagtttcc atggtaattc tttagtaact tattagcaag ctgatatgag ataaaaagtt
     4081 actttattga attctttccc ttagtcttcc ttgccaaact tgaatgtatc attctcattg
     4141 acgctttgct gtacttctgg gggttgcttc agcagctctc tcttcattgt ggcagatgcg
     4201 ccaacatgtc tgttgggtcc agaagtctgt atgtacctat ctgataaaga agttctcaga
     4261 gctgactgaa aatccaaatt tcagccaaca ctttgggcca agggaaagat aacagaaaat
     4321 gtgcaaagca gtactgttca tattagaagg gcagtgaaga attaccatgc acacagaatt
     4381 agcttgaaac agtactgtct cctagggtgt ggtctccagg ccagatcagg ttatgggatc
     4441 ccatagatta tgtacgtaga ctgcacattg gtgggaagtt gctaagataa agacttgtcc
     4501 aaaaactaac aaagcaaaag atgtgtttat tggaatgtat agtctgctgt atttcaagtg
     4561 gggtcttcag tgcagcaggt agacctagtt atacagttat gtaagggata gagaactact
     4621 gttaaaaggt ttttatcccc tctcaccact taatctccta tgtatgttag gatggctagt
     4681 gatgacctga acatcttggt aacagacaga ggtcttacct ggaggactaa agcagtactt
     4741 agcttaaata cttgaaagga caaagttatc aaaatacgtt gattaggatt atttaaggtc
     4801 atgtgacact gatcttttct tctgggtcac gtagaggata ggttcttgcc acactcttat
     4861 tcagagtttc cttggtaagc tgtaattgca gcccatacca gtttgacctg gcccaggact
     4921 acatgctggg gatgctcacc aggagtcgcc cctggtctca gcccctctcc tctttatttc
     4981 agagaaggat gcttgagcat tgggcacaga tgctgaggtg gtttgattag ctgaaaaacc
     5041 aagttctgat tcaggtgttg gggcatcatg ttctgtttct cttggaaacc cagcctgctc
     5101 tcatagatac ctacttccat cacatatcct gagcattgcc aaaagaagcc atttagcagc
     5161 tgctgttttt ctctcagcac aaatatattt gctacagaag aattctcttt tctctggtcc
     5221 tggtccccag acctcagaat ctgttaactg ctcttccctg ctgcactgaa tatggttcta
     5281 ggttttgaag agggaatttg aagcaatagg caatcagggc ttggttgaat tggtcttgca
     5341 tatatcctgt cttaatcctc tgaggtgatg agacactgct catgtgacct tctacctttg
     5401 tggatccctc ttggtttgtg accttcgtac cttccctgag gttgtacaaa cttgacaaaa
     5461 gttaatactt ttgtattctc tgcactgttg cactcttcaa atagccccct gaatattaac
     5521 ttgatataca catctttctc ttttatgtct acagtatttt ttcctttttt ttttttgaag
     5581 gttatctgct gttgaattca ataaatttgt ttacctaa
//
