LOCUS       NM_001024504            3059 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus defective in cullin neddylation 1 domain containing 2
            (Dcun1d2), transcript variant 1, mRNA.
ACCESSION   NM_001024504
VERSION     NM_001024504.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3059)
  AUTHORS   Evsikov AV, Graber JH, Brockman JM, Hampl A, Holbrook AE, Singh P,
            Eppig JJ, Solter D and Knowles BB.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   2  (bases 1 to 3059)
  AUTHORS   Kurz T, Ozlu N, Rudolf F, O'Rourke SM, Luke B, Hofmann K, Hyman AA,
            Bowerman B and Peter M.
  TITLE     The conserved protein DCN-1/Dcn1p is required for cullin
            neddylation in C. elegans and S. cerevisiae
  JOURNAL   Nature 435 (7046), 1257-1261 (2005)
   PUBMED   15988528
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY232055.1, BU053156.1, AK155726.1 and DV648583.1.
            
            [WARNING] On Dec 21, 2023 this sequence was replaced by
            NM_001024504.3.
            
            On Aug 4, 2006 this sequence version replaced NM_001024504.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest protein (isoform a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK155726.1, SRR13422597.1266766.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-272               BY232055.1         1-272
            273-285             BU053156.1         181-193
            286-3033            AK155726.1         2-2749
            3034-3059           DV648583.1         269-294
FEATURES             Location/Qualifiers
     source          1..3059
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 5.73 cM"
     gene            1..3059
                     /gene="Dcun1d2"
                     /gene_synonym="DCNL2; mFLJ10704"
                     /note="defective in cullin neddylation 1 domain containing
                     2"
                     /db_xref="GeneID:102323"
                     /db_xref="MGI:MGI:2142792"
     exon            1..323
                     /gene="Dcun1d2"
                     /gene_synonym="DCNL2; mFLJ10704"
                     /inference="alignment:Splign:2.1.0"
     CDS             321..1100
                     /gene="Dcun1d2"
                     /gene_synonym="DCNL2; mFLJ10704"
                     /note="isoform a is encoded by transcript variant 1;
                     DCN1-like protein 2; DCUN1 domain-containing protein 2;
                     defective in cullin neddylation protein 1-like protein 2;
                     DCN1, defective in cullin neddylation 1, domain containing
                     2"
                     /codon_start=1
                     /product="DCN1-like protein 2 isoform a"
                     /protein_id="NP_001019675.2"
                     /db_xref="CCDS:CCDS40228.1"
                     /db_xref="GeneID:102323"
                     /db_xref="MGI:MGI:2142792"
                     /translation="MHKLKSAQKDKVRQFMACTQASERTAIYCLTQNEWKLDEATDSF
                     FQNPEAFHRESMKSSVDQKKLEQLYSRYKDPQDENKIGIDGIQQFCDDLSLDPASISV
                     LVIAWKFRAATQCEFSKKEFVDGMTELGCDSTERLKALLPRLEQELKDPAKFKDLYQF
                     TFTFAKNPGQKGLDLEMAVAYWKLVLSGRFKFLDLWNTFLLEHHKRSIPRDTWNLLLD
                     FGNMIADDLSNYDEEGAWPVLIDDFVEYARPVVTGGRRSPF"
     exon            324..540
                     /gene="Dcun1d2"
                     /gene_synonym="DCNL2; mFLJ10704"
                     /inference="alignment:Splign:2.1.0"
     exon            541..709
                     /gene="Dcun1d2"
                     /gene_synonym="DCNL2; mFLJ10704"
                     /inference="alignment:Splign:2.1.0"
     exon            710..840
                     /gene="Dcun1d2"
                     /gene_synonym="DCNL2; mFLJ10704"
                     /inference="alignment:Splign:2.1.0"
     exon            841..923
                     /gene="Dcun1d2"
                     /gene_synonym="DCNL2; mFLJ10704"
                     /inference="alignment:Splign:2.1.0"
     exon            924..1020
                     /gene="Dcun1d2"
                     /gene_synonym="DCNL2; mFLJ10704"
                     /inference="alignment:Splign:2.1.0"
     exon            1021..3034
                     /gene="Dcun1d2"
                     /gene_synonym="DCNL2; mFLJ10704"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3015..3020
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dcun1d2"
                     /gene_synonym="DCNL2; mFLJ10704"
     polyA_site      3034
                     /gene="Dcun1d2"
                     /gene_synonym="DCNL2; mFLJ10704"
ORIGIN      
        1 gggaactgga gtcccgggag ccggccggcc agccagcttc cagagagtgc gtaagcctaa
       61 gagcctcaga acagcaacag cctccgagag aggttacgat gtgacccaaa cgctgtgcct
      121 cggagctgag gggcgcctgt ccacgctgca cgcggagagc cgaagacgga gcgagccccc
      181 ccagtcacct gaagggagcg ttcgaacact gcgcctgcgc agagcgcctg ctgctagccg
      241 ccgcggcaat cgcctgcgca gaggaagagc ggcgtgcgct tgcgcagaaa attgaagtcg
      301 cttcggcagc cttggggagc atgcataaac ttaaatcagc tcagaaggac aaggtccgcc
      361 agttcatggc atgcactcag gctagcgaga ggactgccat ctactgcttg acacagaatg
      421 agtggaaact agatgaggcc acagacagtt tcttccaaaa ccccgaggcg tttcaccgag
      481 agtctatgaa gagcagtgtg gaccagaaga agctggagca actgtacagc aggtacaaag
      541 acccacagga cgaaaacaaa attggaatcg atgggattca gcagttctgt gatgacctga
      601 gtctggaccc cgccagtatc agcgttttgg tcatagcgtg gaagttcagg gccgccactc
      661 aatgtgaatt tagcaaaaag gaatttgtgg atggcatgac ggagctgggg tgtgatagca
      721 ccgagaggct gaaagctctt ctccccagac tggagcaaga gcttaaggac ccagccaagt
      781 tcaaggacct ttaccagttt accttcacct tcgctaagaa ccctgggcag aagggcttag
      841 atttagaaat ggctgttgca tattggaagt tagtattgtc tggaaggttt aagtttttag
      901 atctttggaa cacatttctg ctggagcatc acaaaagatc aattccaagg gatacttgga
      961 accttctcct agattttgga aacatgattg cagatgattt gtctaactac gatgaagaag
     1021 gagcatggcc tgtccttata gatgactttg tagaatacgc acggccagtg gtcacaggcg
     1081 ggagacgcag ccctttctag atggaaaagc cggatggcgg gtaggatggg cgtgtcttgg
     1141 aggagacagc tgcgtgggtt gctgtgtgca tttgtcgctg acctcagagt cttcctcgtc
     1201 cactcatgaa gcaaaccctt actctgctta aaggctgcag tggctgacgt gcagacacac
     1261 agaagcgcct cgggacatcg gggacatggg cagacctagt gctttagaag ccgcctgcat
     1321 gacttgtctt tagagaaagc aacgtagacc ctgttcgcag ggctgagagc ttgctgtcca
     1381 gctcctgacg ttacggtgag caccagccgt ttccaaactg gaatcatgtt acagttatgc
     1441 ttcaaagcag cacctgtgtc ctcagaatga cgtatctttt acacaagtcc aagctgttaa
     1501 acacacgcct caggaaggtg gccttgcccg agagcccact gcttttaatc ttggtattca
     1561 agatggatag ttttgaatta tcaaatctct agatttacta gatgctttgc tttcattttc
     1621 tctagaagag actgttgcag tttgcacagg gtggctggca caggataggt ccagcaggtt
     1681 catatccaac tgttgacaag ctggtcggcc agttcacttc taatgaggtt atcactatag
     1741 gcctggatgc tgcctcctga gaagtttctt atttttttaa tatattttat atttaaaagg
     1801 acgttttcca tgagaaacac ttctttttga gtgatgaatt agatttacaa atcagatgca
     1861 ccagttcccg tcacctgtct atgatgtttt cagtgcccag tgtccagccc ttcgaaagcc
     1921 atatacattt ggaagcaaac atacgtcatc cagaaggaat ccacacccaa agccctgtct
     1981 cacctgtctg cgcctgggtc tgtgccgtgt caccgtgccg tgtcaccatc tgcttttcca
     2041 gtgtttttct ggtcagcgtg cactcatgca cacaggcata gagggcctgg atcctacctg
     2101 ctcatctggt gtcaagcttc gaacatcact gtgctgaccc tacctcacac ttgccaagac
     2161 ttggtgtcac acgcgtgcct tgctgcccag cctacagggc cgtggggcag atatgctggg
     2221 cccacttcag gacaggggac tcgtcaatgc ctaaacacag aaagcatgcc ccatatgtgc
     2281 tgtagggcag ctcctggtac tggggcctgc tcctggggta ggaagcagct ctgaggcatg
     2341 cgtgccctac gaggtggaca ttgctaatga acgggaatct cacaggaggt ggagggtcag
     2401 aactggaaac cagtctccac aaagccagcc cctcggtgcg tgagatgaca tcactagtgg
     2461 cctgtcagcg caggtctgtc aagggacaac cgggacatct ttgagagcgt acgtaaccaa
     2521 actgacttag tgaaaacctg gaaaacaact tccttccagg ctttgtgggt tcctgacttg
     2581 tagttaactt ctgttcagag aagtttatag atacaaagaa ctaaatcttg aaggtctgca
     2641 atacattctt atttctaaga tttaacattc ttcagggaaa ggagcagtga tatgattgag
     2701 caggtgaagg catgtgctgc ccagcctgag ttcagtccct gcgagccacg tggtggaggg
     2761 gagaagtgac ttctccagtt gtcctctgac ctccacacat gtgccatgaa atgcatgtac
     2821 tccccacaca catgtactca cacagtaaaa caaataggca aacaagcata aataagttaa
     2881 gttctatggg attgtcaata ggctgtgaca taccagtaat tgataaaggc tttttaaaca
     2941 attgtgcttt ctgttctctt atttacactt gaattgtgca tgttacagaa atgctgaaaa
     3001 cttcagacat agtaaataaa atattttccc tggtaaaaaa aaaaaaaaaa aaaaaaaaa
//
