LOCUS       NM_178788               1884 bp    mRNA    linear   ROD 02-JUL-2024
DEFINITION  Mus musculus dCMP deaminase (Dctd), transcript variant 1, mRNA.
ACCESSION   NM_178788
VERSION     NM_178788.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1884)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1884)
  AUTHORS   Rutledge,E.A., Benazet,J.D. and McMahon,A.P.
  TITLE     Cellular heterogeneity in the ureteric progenitor niche and
            distinct profiles of branching morphogenesis in organ development
  JOURNAL   Development 144 (17), 3177-3188 (2017)
   PUBMED   28705898
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC164420.4.
            
            On Apr 6, 2021 this sequence version replaced NM_178788.4.
            
            Transcript Variant: This variant (1) represents the longest
            transcript. Variants 1, 2 and 3 encode the same protein.
            
            CCDS Note: The coding region has been updated to shorten the CDS to
            begin from a downstream start codon based on conservation.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC031719.1, AK077663.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation,
                                                expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-79                AC164420.4         136611-136689       c
            80-211              AC164420.4         135069-135200       c
            212-347             AC164420.4         134756-134891       c
            348-464             AC164420.4         109485-109601       c
            465-561             AC164420.4         107981-108077       c
            562-1884            AC164420.4         105194-106516       c
FEATURES             Location/Qualifiers
     source          1..1884
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 26.98 cM"
     gene            1..1884
                     /gene="Dctd"
                     /gene_synonym="6030466N05Rik"
                     /note="dCMP deaminase"
                     /db_xref="GeneID:320685"
                     /db_xref="MGI:MGI:2444529"
     exon            1..79
                     /gene="Dctd"
                     /gene_synonym="6030466N05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            80..211
                     /gene="Dctd"
                     /gene_synonym="6030466N05Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             104..640
                     /gene="Dctd"
                     /gene_synonym="6030466N05Rik"
                     /EC_number="3.5.4.12"
                     /codon_start=1
                     /product="deoxycytidylate deaminase"
                     /protein_id="NP_848903.3"
                     /db_xref="CCDS:CCDS22302.2"
                     /db_xref="GeneID:320685"
                     /db_xref="MGI:MGI:2444529"
                     /translation="MSDISCKKRDDYLEWPEYFMAVAFLSAQRSKDPSSQVGACIVNT
                     ENKIVGIGYNGMPNGCSDDLLPWRRTAENKLDTKYPYVCHAELNAIMNKNSADVKGCS
                     MYVALFPCNECAKLIIQAGIKEVIFMSDKYHDSEETTAARLLFKLAGVTFRKFTPKYS
                     KIVIDFDSINSRPSQKPQ"
     exon            212..347
                     /gene="Dctd"
                     /gene_synonym="6030466N05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            348..464
                     /gene="Dctd"
                     /gene_synonym="6030466N05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            465..561
                     /gene="Dctd"
                     /gene_synonym="6030466N05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            562..1884
                     /gene="Dctd"
                     /gene_synonym="6030466N05Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1864..1869
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dctd"
                     /gene_synonym="6030466N05Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      1884
                     /gene="Dctd"
                     /gene_synonym="6030466N05Rik"
                     /note="major polyA site"
ORIGIN      
        1 cccgacttcc tacccgcgcg cacggcggct gtgtggggtg gacggtgcaa gcgtggtctg
       61 cacctcgaag gagcggacgt gacgtatgac ttctacaccc aacatgagtg acatttcctg
      121 caaaaaacgg gatgactatc tggaatggcc cgagtatttc atggcagtgg ccttcttgtc
      181 agcacaaaga agcaaggacc caagttccca ggtgggggcc tgcattgtga acacagaaaa
      241 caagattgtt gggatcgggt acaatggcat gccaaatggg tgcagtgatg acctgttgcc
      301 ttggaggaga acagcagaaa ataagctgga tactaaatat ccttatgtgt gccatgccga
      361 gctgaacgcc atcatgaaca agaactcggc tgatgtgaag ggctgcagca tgtacgtcgc
      421 cttgttcccg tgtaacgaat gtgctaaact catcatccag gcaggtataa aagaggttat
      481 cttcatgtcg gataaatacc acgacagcga ggagacgaca gctgccaggc tcctgtttaa
      541 gttggctggg gttacgttca gaaaattcac accgaagtac agcaagattg tcattgactt
      601 tgattcgatc aatagccgac cgagtcagaa gcctcagtga gtttcgtctc gttaaagccc
      661 cagaagaaga tgacacccca ccacgtgcgt gcacacacac acacacacac acacatacac
      721 acacacacaa ggggctcccc aagcctttca tcttgaagtc ccacggaact ttttaataac
      781 acaacactaa acatctaaag aatataaaac ttggaatctt ctcacccgtc acgtggagct
      841 ccatctgttt cagctgttga tgtagtttgg tttggaaact aagggacctg cccacaggag
      901 ctggagtgaa ggtctctccc cttccgccga gcccgtctgc cagagagtgt cagctctgtc
      961 atccaccata tttcgacagc cgctccttgc tgctacacgg ggtaggagga catacaaata
     1021 attgcttctc gttcttagca gggatgaaca ggcacactga ggtgaacatc tggcccaaat
     1081 gaagcatacc ctgtcacgcc cttgggaaaa caaataggac cgaacaaagc tacatgaaca
     1141 cacctgctgt agagttgagg ggacctctca cctggtcaca tgaggttgag gagggcccag
     1201 tgtcctggca gatgatcagt acagtgtccc cctcaagtca cactttcctg ccttacacag
     1261 agcagtagca taccatccct ctggagggta ggggacccct gcggttccag cctcttagcc
     1321 ttggtttgtt ggtcacatag cactgttaaa tttatccgag gcataagtag ttcctagagg
     1381 agacagtcta tcactccccc tagaccaggc gctttgcggt gacagctgga gctatatgga
     1441 tgggtgatga gagacgttcc cccatcctgt gtctcctgct gtgtggacac atgtcactcc
     1501 tgctccacat gccaacatgg ttcatttcca agggcaccct ataaccagag agcacattaa
     1561 ttcctgtcct ataagagggc tgtgggaaac tgtgtacctg gaggtggtcc atgccagatc
     1621 ctcatttgtg ccttcagctt cataggcagc atacgcctgc tgccccattg tgggtggggg
     1681 tgccccactg cgtactgtgt ttttaatttc atttaacttc tagcagacac gctcagtgtc
     1741 tttgataaaa tagtgtcttt ttttcatgtg tttttatttc atttctaaga tttttttttt
     1801 aacactccgt attctggagc atttttttac aatttggatc tctgccagta ttgttaaaat
     1861 tttattaaaa tcatccagca ccaa
//
