LOCUS       NM_001370853            2379 bp    mRNA    linear   ROD 04-AUG-2024
DEFINITION  Mus musculus DC-STAMP domain containing 2 (Dcst2), mRNA.
ACCESSION   NM_001370853 XM_006502502
VERSION     NM_001370853.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2379)
  AUTHORS   Noda,T., Blaha,A., Fujihara,Y., Gert,K.R., Emori,C., Deneke,V.E.,
            Oura,S., Panser,K., Lu,Y., Berent,S., Kodani,M., Cabrera-Quio,L.E.,
            Pauli,A. and Ikawa,M.
  TITLE     Sperm membrane proteins DCST1 and DCST2 are required for sperm-egg
            interaction in mice and fish
  JOURNAL   Commun Biol 5 (1), 332 (2022)
   PUBMED   35393517
  REMARK    GeneRIF: Sperm membrane proteins DCST1 and DCST2 are required for
            sperm-egg interaction in mice and fish.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2379)
  AUTHORS   Inoue,N., Hagihara,Y. and Wada,I.
  TITLE     Evolutionarily conserved sperm factors, DCST1 and DCST2, are
            required for gamete fusion
  JOURNAL   Elife 10, e66313 (2021)
   PUBMED   33871360
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2379)
  AUTHORS   Lin,Q., Donahue,S.L., Moore-Jarrett,T., Cao,S., Osipovich,A.B. and
            Ruley,H.E.
  TITLE     Mutagenesis of diploid mammalian genes by gene entrapment
  JOURNAL   Nucleic Acids Res 34 (20), e139 (2006)
   PUBMED   17062627
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC171273.1.
            
            On Jun 6, 2019 this sequence version replaced XM_006502502.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849384,
                              SAMN00849389 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-313               AC171273.1         176542-176854       c
            314-484             AC171273.1         176261-176431       c
            485-586             AC171273.1         175852-175953       c
            587-784             AC171273.1         175327-175524       c
            785-850             AC171273.1         174950-175015       c
            851-1064            AC171273.1         174239-174452       c
            1065-1222           AC171273.1         173925-174082       c
            1223-1387           AC171273.1         173304-173468       c
            1388-1555           AC171273.1         171578-171745       c
            1556-1656           AC171273.1         171373-171473       c
            1657-1787           AC171273.1         170510-170640       c
            1788-1915           AC171273.1         169398-169525       c
            1916-2009           AC171273.1         168857-168950       c
            2010-2165           AC171273.1         168593-168748       c
            2166-2379           AC171273.1         164530-164743       c
FEATURES             Location/Qualifiers
     source          1..2379
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 39.09 cM"
     gene            1..2379
                     /gene="Dcst2"
                     /gene_synonym="Gm760"
                     /note="DC-STAMP domain containing 2"
                     /db_xref="GeneID:329702"
                     /db_xref="MGI:MGI:2685606"
     exon            1..313
                     /gene="Dcst2"
                     /gene_synonym="Gm760"
                     /inference="alignment:Splign:2.1.0"
     CDS             82..2187
                     /gene="Dcst2"
                     /gene_synonym="Gm760"
                     /codon_start=1
                     /product="DC-STAMP domain-containing protein 2"
                     /protein_id="NP_001357782.1"
                     /db_xref="CCDS:CCDS89657.1"
                     /db_xref="GeneID:329702"
                     /db_xref="MGI:MGI:2685606"
                     /translation="MEEGSSTARAVVRSTCGFTVGLSLATAFGLLELLGEGHSPFGCL
                     VTTVTLAAFLSLGMGFSRQVRVSVLLLLPQAFSKQSRLLLLVASFGLVLQGPCANTLQ
                     NFTRASEAVACGAELALNQTAEMLERAKQPLISALSKIKAIAQKAKVVGDRIRKFFRS
                     IIDAVKHIARCLQNVWYWLLHIGDMCNSELGNPYSKCTQVFDDAKIHCMKVVSGFPHL
                     CYALLPYKLLVCGLASLVQKFCVLPSYLEFFLRTVIRTPVMKLLGKLRREFEFNMTAT
                     HYFSVDLNSSRSLSQVALDLQEAVSMKLYTAREALSLMGYTMPLLIGFLYIQALCYRY
                     YYLNSDKFDNVYITRRFLDMEAVRSLAGMPTVLPLSSHEAKHYIQPDSMFLSQREQMF
                     YTLEIFNLTRHLLIMLLLVFLDYGVFWLLDLARYHLQGEIVARSPVVVSISVEGSGYS
                     GNIYRDLASAFDVMQQGNVSVLSPRCTLHPSEPDAKGYIVIGTMYGLCFFVTLFGSYV
                     SRLRRAICASYYPSREQERITYLYNMLLSHRTNITATVQRAVRRRSADQGQMNILQVL
                     AIRLPFLRPLLGPFSLQQSYCMGCGEPEDKGGMENFVSCSTPGCRGLYCPTCFRLLNN
                     TCSVCSAPLSNQGHLDLELDSSDEESPQLWLAAARRKAPEQELKLRQQLQEALGTNLS
                     DKSTSKPERAGNRNQDRKQ"
     exon            314..484
                     /gene="Dcst2"
                     /gene_synonym="Gm760"
                     /inference="alignment:Splign:2.1.0"
     exon            485..586
                     /gene="Dcst2"
                     /gene_synonym="Gm760"
                     /inference="alignment:Splign:2.1.0"
     exon            587..784
                     /gene="Dcst2"
                     /gene_synonym="Gm760"
                     /inference="alignment:Splign:2.1.0"
     exon            785..850
                     /gene="Dcst2"
                     /gene_synonym="Gm760"
                     /inference="alignment:Splign:2.1.0"
     exon            851..1064
                     /gene="Dcst2"
                     /gene_synonym="Gm760"
                     /inference="alignment:Splign:2.1.0"
     exon            1065..1222
                     /gene="Dcst2"
                     /gene_synonym="Gm760"
                     /inference="alignment:Splign:2.1.0"
     exon            1223..1387
                     /gene="Dcst2"
                     /gene_synonym="Gm760"
                     /inference="alignment:Splign:2.1.0"
     exon            1388..1555
                     /gene="Dcst2"
                     /gene_synonym="Gm760"
                     /inference="alignment:Splign:2.1.0"
     exon            1556..1656
                     /gene="Dcst2"
                     /gene_synonym="Gm760"
                     /inference="alignment:Splign:2.1.0"
     exon            1657..1787
                     /gene="Dcst2"
                     /gene_synonym="Gm760"
                     /inference="alignment:Splign:2.1.0"
     exon            1788..1915
                     /gene="Dcst2"
                     /gene_synonym="Gm760"
                     /inference="alignment:Splign:2.1.0"
     exon            1916..2009
                     /gene="Dcst2"
                     /gene_synonym="Gm760"
                     /inference="alignment:Splign:2.1.0"
     exon            2010..2165
                     /gene="Dcst2"
                     /gene_synonym="Gm760"
                     /inference="alignment:Splign:2.1.0"
     exon            2166..2379
                     /gene="Dcst2"
                     /gene_synonym="Gm760"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2353..2358
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dcst2"
                     /gene_synonym="Gm760"
                     /note="hexamer: AATAAA"
     polyA_site      2379
                     /gene="Dcst2"
                     /gene_synonym="Gm760"
                     /note="major polyA site"
ORIGIN      
        1 acctgaagac tctccaggcc tttcctggag acacactggc cttgggtccc agcagccata
       61 gtcaacgctg atgttttgac catggaggag gggtccagca cggcacgggc cgtggtccgt
      121 agtacctgtg gctttaccgt gggtttgtcc ttggccaccg cctttgggct cctagagctt
      181 ctaggggaag gacacagccc ctttggctgc ctggtgacca ccgtcacttt ggctgccttc
      241 ctgagcttgg gcatggggtt ctcccggcag gtccgcgtct ctgtgctctt gctgcttcca
      301 caggccttct ccaagcagag ccggttgctg ctactggtag cttcctttgg gctggtgcta
      361 caagggcctt gtgcgaacac cctgcagaac ttcacccggg caagtgaagc tgtggcttgt
      421 ggggcagagc tggccctgaa ccagacggct gaaatgctgg agcgggccaa gcagcccctt
      481 atcagtgctc tgtctaagat taaagctatt gcccagaagg ccaaagtggt gggtgaccgg
      541 atacgcaagt tcttccggtc cattatagat gccgtgaaac acatagccag gtgcctgcag
      601 aatgtgtggt attggctcct tcatattggt gatatgtgca actccgagct gggcaaccct
      661 tactcaaaat gcacacaggt gtttgatgat gccaagatcc actgtatgaa ggtcgtttcg
      721 ggattccctc acctgtgtta tgcgctcttg ccctacaaac tgctggtctg tggacttgcc
      781 agcttggtcc agaaattctg tgtcttgcct tcctacctcg aatttttcct gcgaacggtc
      841 atccgcactc ccgtgatgaa actgcttggc aagctacgtc gagagtttga gttcaacatg
      901 acagccaccc actacttctc tgtggacctc aattcctctc ggagcctgtc ccaggtggct
      961 ttggacctgc aggaggctgt cagcatgaag ttgtacactg ccagggaggc gctgtctttg
     1021 atgggctaca ccatgcctct gcttattgga tttctctaca tccaagccct gtgttaccgg
     1081 tactattatc tgaactccga caaattcgac aatgtctata ttaccaggcg cttcctagac
     1141 atggaggcag tacgctccct tgcagggatg cctacggtgc tgcctctcag ttctcatgag
     1201 gccaaacact acatccagcc agactccatg ttcctgagcc agcgggaaca gatgttttat
     1261 accttggaga tctttaacct cacccgccat ctcctcatca tgctcctcct ggtctttctg
     1321 gactatggcg tcttctggct acttgatctg gcccggtacc acctccaggg cgagattgta
     1381 gcccgcagcc ctgtggtagt gtctatatcg gtggaagggt ccggctactc agggaatatt
     1441 taccgtgacc tggcgtcagc gtttgatgtt atgcaacaag gcaacgtcag tgtattgtcg
     1501 ccgcgctgca ccctgcaccc ctcagaaccg gatgctaagg gttacatcgt tattggtacc
     1561 atgtacggtc tgtgcttctt cgtcactctg tttggcagct atgtcagcag gctgcggcgt
     1621 gctatctgtg cctcctatta ccccagcagg gaacaggaaa ggatcaccta cctttacaac
     1681 atgcttctga gccatcggac caacataacg gcgacagtgc agcgagcagt gaggcgacgg
     1741 tcagctgacc aaggccaaat gaatatcctc caggtgctgg ccatccggtt gccttttcta
     1801 aggccattgc ttggcccgtt ttcgctgcag cagtcttact gcatgggctg tggggagcct
     1861 gaagacaaag ggggcatgga gaactttgtg tcctgcagta ccccaggctg cagaggtctc
     1921 tactgcccta cctgtttccg tctcctaaac aacacctgtt ctgtgtgttc tgctccactc
     1981 tccaaccagg ggcacctgga cctggagctg gactccagtg atgaggagag tcctcagctg
     2041 tggctggctg cagctcgaag aaaggccccc gagcaggagc tgaaacttcg acaacagctt
     2101 caggaagcac tgggcacgaa cctttcagac aagtccacct ccaagcccga gcgagcagga
     2161 aacaggaacc aggacagaaa gcagtgactt cagaggaagc gtccacagca tctcccagaa
     2221 gctcatctgg ctttgtgggc ctcccctttc tcccagaacc ccaggcacca cttcggaaat
     2281 ccctgtcccc aaacaagacc cctccccagc ctcagaccct cccgacccct cccactgccg
     2341 cccccctccc ccaataaagg aaccaaaagt ggacacaaa
//
