LOCUS       NM_001410030             645 bp    mRNA    linear   ROD 19-NOV-2024
DEFINITION  Mus musculus demilune cell and parotid protein 1 (Dcpp1),
            transcript variant 2, mRNA.
ACCESSION   NM_001410030
VERSION     NM_001410030.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 645)
  AUTHORS   Aure,M.H., Symonds,J.M., Villapudua,C.U., Dodge,J.T., Werner,S.,
            Knosp,W.M. and Hoffman,M.P.
  TITLE     FGFR2 is essential for salivary gland duct homeostasis and
            MAPK-dependent seromucous acinar cell differentiation
  JOURNAL   Nat Commun 14 (1), 6485 (2023)
   PUBMED   37838739
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 645)
  AUTHORS   Wang,Y., Weber,M., Foreman,O., Remy,H., Mracsko,E.Z. and
            Hanson,J.E.
  TITLE     Comment on 'Inflammasome inhibition prevents alpha-synuclein
            pathology and dopaminergic neurodegeneration in mice'
  JOURNAL   Sci Transl Med 15 (696), eade8728 (2023)
   PUBMED   37196063
  REMARK    GeneRIF: Comment on 'Inflammasome inhibition prevents
            alpha-synuclein pathology and dopaminergic neurodegeneration in
            mice'.
REFERENCE   3  (bases 1 to 645)
  AUTHORS   Song,H., Song,J., Kim,Y.J., Jeong,H.H., Min,H.J. and Koh,S.S.
  TITLE     DCPP1 is the mouse ortholog of human PAUF that possesses functional
            analogy in pancreatic cancer
  JOURNAL   Biochem Biophys Res Commun 493 (4), 1498-1503 (2017)
   PUBMED   28988106
  REMARK    GeneRIF: Mouse DCPP1 exerted its function on pancreatic cancer
            cells by activating intracellular signaling pathways involved in
            aggressive cancer phenotype of human pancreatic cancer cells. The
            objective of this study was to evaluate the potential of DCPP1 as a
            putative mouse ortholog of human PAUF by sequence alignment and
            functional studies.
REFERENCE   4  (bases 1 to 645)
  AUTHORS   Maruyama,E.O., Aure,M.H., Xie,X., Myal,Y., Gan,L. and Ovitt,C.E.
  TITLE     Cell-Specific Cre Strains For Genetic Manipulation in Salivary
            Glands
  JOURNAL   PLoS One 11 (1), e0146711 (2016)
   PUBMED   26751783
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 645)
  AUTHORS   Xue,L., Cai,J.Y., Ma,J., Huang,Z., Guo,M.X., Fu,L.Z., Shi,Y.B. and
            Li,W.X.
  TITLE     Global expression profiling reveals genetic programs underlying the
            developmental divergence between mouse and human embryogenesis
  JOURNAL   BMC Genomics 14, 568 (2013)
   PUBMED   23961710
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 645)
  AUTHORS   Gontan,C., de Munck,A., Vermeij,M., Grosveld,F., Tibboel,D. and
            Rottier,R.
  TITLE     Sox2 is important for two crucial processes in lung development:
            branching morphogenesis and epithelial cell differentiation
  JOURNAL   Dev Biol 317 (1), 296-309 (2008)
   PUBMED   18374910
REFERENCE   7  (bases 1 to 645)
  AUTHORS   Mullins,J.J., Mullins,L.J., Dunbar,D.R., Brammar,W.J., Gross,K.W.
            and Morley,S.D.
  TITLE     Identification of a human ortholog of the mouse Dcpp gene locus,
            encoding a novel member of the CSP-1/Dcpp salivary protein family
  JOURNAL   Physiol Genomics 28 (1), 129-140 (2006)
   PUBMED   16954406
REFERENCE   8  (bases 1 to 645)
  AUTHORS   Lee,K.F., Xu,J.S., Lee,Y.L. and Yeung,W.S.
  TITLE     Demilune cell and parotid protein from murine oviductal epithelium
            stimulates preimplantation embryo development
  JOURNAL   Endocrinology 147 (1), 79-87 (2006)
   PUBMED   16239302
  REMARK    GeneRIF: Dcpp is highly expressed in the oviductal lumen in the
            presence of preimplantation embryos.
REFERENCE   9  (bases 1 to 645)
  AUTHORS   Okubo,T. and Hogan,B.L.
  TITLE     Hyperactive Wnt signaling changes the developmental potential of
            embryonic lung endoderm
  JOURNAL   J Biol 3 (3), 11 (2004)
   PUBMED   15186480
REFERENCE   10 (bases 1 to 645)
  AUTHORS   Bekhor,I., Wen,Y., Shi,S., Hsieh,C.H., Denny,P.A. and Denny,P.C.
  TITLE     cDNA cloning, sequencing and in situ localization of a transcript
            specific to both sublingual demilune cells and parotid intercalated
            duct cells in mouse salivary glands
  JOURNAL   Arch Oral Biol 39 (12), 1011-1022 (1994)
   PUBMED   7717881
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC110262.12.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BG869682.1, BF303260.1 [ECO:0000332]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-32                AC110262.12        95987-96018
            33-143              AC110262.12        96078-96188
            144-246             AC110262.12        96480-96582
            247-645             AC110262.12        97564-97962
FEATURES             Location/Qualifiers
     source          1..645
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 12.11 cM"
     gene            1..645
                     /gene="Dcpp1"
                     /gene_synonym="Dcpp; Dcpp-1; p20"
                     /note="demilune cell and parotid protein 1"
                     /db_xref="GeneID:13184"
                     /db_xref="MGI:MGI:105949"
     exon            1..32
                     /gene="Dcpp1"
                     /gene_synonym="Dcpp; Dcpp-1; p20"
                     /inference="alignment:Splign:2.1.0"
     exon            33..143
                     /gene="Dcpp1"
                     /gene_synonym="Dcpp; Dcpp-1; p20"
                     /inference="alignment:Splign:2.1.0"
     CDS             71..586
                     /gene="Dcpp1"
                     /gene_synonym="Dcpp; Dcpp-1; p20"
                     /note="common salivary protein 1"
                     /codon_start=1
                     /product="demilune cell and parotid protein precursor"
                     /protein_id="NP_001396959.1"
                     /db_xref="GeneID:13184"
                     /db_xref="MGI:MGI:105949"
                     /translation="MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSAPEGKN
                     ITSIRVFLKGRLIVGIQLNYDDNKDGQVYGSTAGKEMVARLSKEEHIIAAQGTYTPSA
                     LTQIIFTTNQPRQLMVGYYVGNSEYSSFPNDPSHVLKGACVSWRAGGIKSILFLWGSE
                     NSSCVKYGHSG"
     exon            144..246
                     /gene="Dcpp1"
                     /gene_synonym="Dcpp; Dcpp-1; p20"
                     /inference="alignment:Splign:2.1.0"
     exon            247..645
                     /gene="Dcpp1"
                     /gene_synonym="Dcpp; Dcpp-1; p20"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acaagacacc caaggcgaaa cctctcagcc agacttgggt ggtctttgct ctttcccctc
       61 agactttgag atgttccagc tggaggccat gctggcctta ctgattcttg ccttcttggg
      121 cacccccacc gttttgacac aagattatca tggtccagaa gttggaaaac attcctgcac
      181 tagtgcacct gaaggaaaaa atataacaag tatccgggta tttcttaagg gtagattgat
      241 tgttggaatt cagctcaact atgatgacaa caaggacggt caagtgtatg gctctactgc
      301 cgggaaggaa atggtagcca gactgtctaa ggaagagcac atcattgcag cccagggcac
      361 atacactcct tcggctttaa ctcagataat ctttacgacc aaccagcctc gccagctaat
      421 ggtggggtat tatgtgggca attctgagta ctctagcttc cctaacgatc ccagccatgt
      481 gctcaaggga gcttgtgtct cttggagggc aggtggcata aagagtatct tgtttttgtg
      541 gggaagtgaa aacagttcat gtgtgaaata tggccactca ggctgaagtg gtctgtgtca
      601 ggtacttcca aactgaaccc atgaataaat acaacatctg catga
//
