LOCUS       NM_133761               5525 bp    mRNA    linear   ROD 29-OCT-2024
DEFINITION  Mus musculus decapping mRNA 1A (Dcp1a), transcript variant 1, mRNA.
ACCESSION   NM_133761
VERSION     NM_133761.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5525)
  AUTHORS   Zhang,Y., Kang,H.R., Jun,Y., Kang,H., Bang,G., Ma,R., Ju,S.,
            Yoon,D.E., Kim,Y., Kim,K., Kim,J.Y. and Han,K.
  TITLE     Neurodevelopmental disorder-associated CYFIP2 regulates
            membraneless organelles and eIF2alpha phosphorylation via protein
            interactors and actin cytoskeleton
  JOURNAL   Hum Mol Genet 33 (19), 1671-1687 (2024)
   PUBMED   38981622
REFERENCE   2  (bases 1 to 5525)
  AUTHORS   Kim,J., Muraoka,M., Okada,H., Toyoda,A., Ajima,R. and Saga,Y.
  TITLE     The RNA helicase DDX6 controls early mouse embryogenesis by
            repressing aberrant inhibition of BMP signaling through
            miRNA-mediated gene silencing
  JOURNAL   PLoS Genet 18 (10), e1009967 (2022)
   PUBMED   36197846
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5525)
  AUTHORS   Wei,W., Chen,Q., Liu,M., Sheng,Y., OuYang,Q., Feng,W., Yang,X.,
            Ding,L., Su,S., Zhang,J., Fang,L., Vidal-Puig,A., Wang,H.Y. and
            Chen,S.
  TITLE     TRIM24 is an insulin-responsive regulator of P-bodies
  JOURNAL   Nat Commun 13 (1), 3972 (2022)
   PUBMED   35803934
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5525)
  AUTHORS   Roy,N., Sundar,S., Pillai,M., Patell-Socha,F., Ganesh,S.,
            Aloysius,A., Rumman,M., Gala,H., Hughes,S.M., Zammit,P.S. and
            Dhawan,J.
  TITLE     mRNP granule proteins Fmrp and Dcp1a differentially regulate mRNP
            complexes to contribute to control of muscle stem cell quiescence
            and activation
  JOURNAL   Skelet Muscle 11 (1), 18 (2021)
   PUBMED   34238354
  REMARK    GeneRIF: mRNP granule proteins Fmrp and Dcp1a differentially
            regulate mRNP complexes to contribute to control of muscle stem
            cell quiescence and activation.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5525)
  AUTHORS   Ibayashi,M., Aizawa,R. and Tsukamoto,S.
  TITLE     mRNA decapping factor Dcp1a is essential for embryonic growth in
            mice
  JOURNAL   Biochem Biophys Res Commun 555, 128-133 (2021)
   PUBMED   33813271
  REMARK    GeneRIF: mRNA decapping factor Dcp1a is essential for embryonic
            growth in mice.
REFERENCE   6  (bases 1 to 5525)
  AUTHORS   Zheng,D., Ezzeddine,N., Chen,C.Y., Zhu,W., He,X. and Shyu,A.B.
  TITLE     Deadenylation is prerequisite for P-body formation and mRNA decay
            in mammalian cells
  JOURNAL   J Cell Biol 182 (1), 89-101 (2008)
   PUBMED   18625844
REFERENCE   7  (bases 1 to 5525)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   8  (bases 1 to 5525)
  AUTHORS   Bai,R.Y., Koester,C., Ouyang,T., Hahn,S.A., Hammerschmidt,M.,
            Peschel,C. and Duyster,J.
  TITLE     SMIF, a Smad4-interacting protein that functions as a co-activator
            in TGFbeta signalling
  JOURNAL   Nat Cell Biol 4 (3), 181-190 (2002)
   PUBMED   11836524
  REMARK    GeneRIF: Overexpression of wild-type SMIF enhanced expression of
            TGFbeta/BMP regulated genes, whereas a dominant-negative SMIF
            mutant suppressed expression.
REFERENCE   9  (bases 1 to 5525)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   10 (bases 1 to 5525)
  AUTHORS   Usui,H., Ichikawa,T., Kobayashi,K. and Kumanishi,T.
  TITLE     Cloning of a novel murine gene Sfmbt, Scm-related gene containing
            four mbt domains, structurally belonging to the Polycomb group of
            genes
  JOURNAL   Gene 248 (1-2), 127-135 (2000)
   PUBMED   10806358
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC119886.7.
            
            On Sep 1, 2022 this sequence version replaced NM_133761.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR10223971.14021.1,
                                           SRR9219382.199602.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-161               AC119886.7         89759-89919         c
            162-202             AC119886.7         87342-87382         c
            203-330             AC119886.7         84989-85116         c
            331-397             AC119886.7         66683-66749         c
            398-536             AC119886.7         63891-64029         c
            537-650             AC119886.7         56478-56591         c
            651-1409            AC119886.7         49898-50656         c
            1410-1475           AC119886.7         47920-47985         c
            1476-1694           AC119886.7         46629-46847         c
            1695-5525           AC119886.7         42519-46349         c
FEATURES             Location/Qualifiers
     source          1..5525
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 18.75 cM"
     gene            1..5525
                     /gene="Dcp1a"
                     /gene_synonym="1110066A22Rik; 4930568L04Rik; D14Ertd817e;
                     Mitc1; SMIF"
                     /note="decapping mRNA 1A"
                     /db_xref="GeneID:75901"
                     /db_xref="MGI:MGI:1923151"
     exon            1..161
                     /gene="Dcp1a"
                     /gene_synonym="1110066A22Rik; 4930568L04Rik; D14Ertd817e;
                     Mitc1; SMIF"
                     /inference="alignment:Splign:2.1.0"
     exon            162..202
                     /gene="Dcp1a"
                     /gene_synonym="1110066A22Rik; 4930568L04Rik; D14Ertd817e;
                     Mitc1; SMIF"
                     /inference="alignment:Splign:2.1.0"
     exon            203..330
                     /gene="Dcp1a"
                     /gene_synonym="1110066A22Rik; 4930568L04Rik; D14Ertd817e;
                     Mitc1; SMIF"
                     /inference="alignment:Splign:2.1.0"
     exon            331..397
                     /gene="Dcp1a"
                     /gene_synonym="1110066A22Rik; 4930568L04Rik; D14Ertd817e;
                     Mitc1; SMIF"
                     /inference="alignment:Splign:2.1.0"
     exon            398..536
                     /gene="Dcp1a"
                     /gene_synonym="1110066A22Rik; 4930568L04Rik; D14Ertd817e;
                     Mitc1; SMIF"
                     /inference="alignment:Splign:2.1.0"
     exon            537..650
                     /gene="Dcp1a"
                     /gene_synonym="1110066A22Rik; 4930568L04Rik; D14Ertd817e;
                     Mitc1; SMIF"
                     /inference="alignment:Splign:2.1.0"
     exon            651..1409
                     /gene="Dcp1a"
                     /gene_synonym="1110066A22Rik; 4930568L04Rik; D14Ertd817e;
                     Mitc1; SMIF"
                     /inference="alignment:Splign:2.1.0"
     exon            1410..1475
                     /gene="Dcp1a"
                     /gene_synonym="1110066A22Rik; 4930568L04Rik; D14Ertd817e;
                     Mitc1; SMIF"
                     /inference="alignment:Splign:2.1.0"
     exon            1476..1694
                     /gene="Dcp1a"
                     /gene_synonym="1110066A22Rik; 4930568L04Rik; D14Ertd817e;
                     Mitc1; SMIF"
                     /inference="alignment:Splign:2.1.0"
     exon            1695..5525
                     /gene="Dcp1a"
                     /gene_synonym="1110066A22Rik; 4930568L04Rik; D14Ertd817e;
                     Mitc1; SMIF"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5494..5499
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dcp1a"
                     /gene_synonym="1110066A22Rik; 4930568L04Rik; D14Ertd817e;
                     Mitc1; SMIF"
                     /note="hexamer: AATAAA"
     polyA_site      5525
                     /gene="Dcp1a"
                     /gene_synonym="1110066A22Rik; 4930568L04Rik; D14Ertd817e;
                     Mitc1; SMIF"
                     /note="major polyA site"
ORIGIN      
        1 ggaggggctc ggctctgaga tccaagatgg agttgttgag tcgagctgag caagagatga
       61 gtctggcggc cttgaaacaa cacgacccct atatcaccag catcgcagac ctcacgggcc
      121 aggtcgccct gtacactttc tgccccaaag ccaaccagtg ggagaagact gatatagaag
      181 ggacgttatt tgtataccga aggtcagctt cgccttacca tggctttacc attgtcaacc
      241 gactgaacat gcacaatctg gttgagccag tgaataaaga tttggaattt cagctccatg
      301 aaccatttct tctgtataga aatgcaagtt tgtcaatata cagtatctgg ttctatgaca
      361 agaatgactg tcatcgcata gcaaaactca tggctgatgt ggtagaagag gagacacggc
      421 gatcccagca ggctgctcga gataaacaga gtcccagcca ggccaatggc tgcagcgacc
      481 agaggcccat agatatcctg gagatgctga gccgggccaa ggatgagtat gagaggaatc
      541 agatgggcgg ctcaaatatc tccagtcctg ggctacagcc aagcactcag ctctctaatc
      601 tgggaagcac cgagactcta gaagagacac cctctgggtc acaggataag tctgctccgt
      661 ctggtcataa acatctgaca gtagaagagt tatttggaac ctccttgcca aaggaacaac
      721 caacagctat gggtctagag tcagaggaca cagacaagct gctgggagat gcatcacaga
      781 aagagcccag ctcattcctc ccatttccct ttgagcagtc agggggagcc cctcagtctg
      841 aaaacctggg tatccattct gccgctcacc acacagttca gcctgaagtc agcaccccag
      901 tgctgatcac tcccgcctcc attgcacagt cgggtgacaa acatccccca agctacacac
      961 tcccactgag ccctgtcctc agccccactc tgccagctga agctcctacc acacaagttc
     1021 cccacttacc tcggaatagc accatgatac aagcagtaaa gaccacaccc aggcagaaat
     1081 ctccactcct gaaccagcca gtccctgagc taagccacag cagtctggtt gctagccaga
     1141 gccccttcag agccccggtg agcctagcaa acccagctgg cacagccctc ccaagcgttg
     1201 atctgcttca gaaactcagg ttgaccccac agcatgacca aatacaagca cagccgcttg
     1261 gaaaaggaac catggcgccc agcttttctt cggcagctgg ccaactggcc acccctgaga
     1321 gcttcataga gccttcttct aagacagcag cagcaagagc agcagtctca gcctccctga
     1381 gcaacatggt gcttgctcca accctccagt ctatgcagca aaaccaggat cctgaagtat
     1441 tttcccagcc taaggtgtta cccagtgcca tcccgattgc aggctctcca ttggttcctg
     1501 caaccaccac agcagtatct tcagtcctgc tgtcccccag tgtgttccag caaacggttc
     1561 ccagggccgc agacctagag aggaaagcca gctccccctc tcccctcact gttgggacag
     1621 cagagagtca gagaaagcct tccattatcc tcagcaagtc tcagctccag gacacactga
     1681 tacacctaat aaagaatgac tccagcttcc tcagtacgct tcatgcagtt tacttgcagg
     1741 ttctgaccaa gaacaaagac aaccacaacc tatgactgca gtgaaggcaa tgtgaaggga
     1801 gagggtccgc ctcaagacac gcaggcttcc tcatggaaca gctaagcaga gcatggagct
     1861 tgaggagcct gagagccttg tccgtaagga tgtttcctag agacgttctc agtgatgatg
     1921 gaggtttcac tgtgcagcat caccagcaaa cctttgtttg acaaaacaac aagagaccat
     1981 tgtgttgagt gacgtgggtg ttttcatcag ctacaagcca gtgggtggaa tgaggagcct
     2041 gactgccggc ttgctttcca ggcctcggga ggagccacca gccttgcagc agagctcagt
     2101 ggagcccacg ccctccctcc tctactccta gaagaactta atgtcagctc acagagtagc
     2161 ttcaggtttt aaggatcaga atttaagttg actctttgga aggtatttgt tcaagtgaag
     2221 tatattttct atgagcaccc cgcttgggcc ttaagacttc tgggatgtct ttgtgttccg
     2281 gtaagtgtcc ctggtcctgc cctgtgcaaa ctccggtgaa gcacagctct tgggataggc
     2341 cggctgggct ctgatggagg aggcttcaca cccttgaagc agaggccggg gccacacaga
     2401 tccagatcct accagaaggc tccattttag tgaactctca gcagtttaag tgtcaagttt
     2461 gtgtgtgaag cgcagcctta ctttcctttt ctgtctaaac acagttcaag ttattgttga
     2521 ttgttttcct taacactttg gcaaaaggac cagtggacca ttctgacaaa gccattctgg
     2581 ttccattcct caaatgtgct gagcagttta aagctatgca gaaagggagc tgtgctcaca
     2641 ctgcctgcct tccttccttc cttagttgta gactctggag tcagaaagca agtgtgagac
     2701 ctagcacctc acagtatatc ctaggctgcg agctctctgg ccgcagtcag aactgtaaag
     2761 atgctttgtg atgctgctat tgatctgcca tggtttctat ttatgctttt atggcatgta
     2821 atggtgtttg gtaatatttt aatgtagaat ttgattattt cagcaatagt aattttgaga
     2881 tattctttga atgaaaagtg tcttcgtttc tatgatacag gtcattttct agtatttaac
     2941 caattaatgc actgcttact tttctgagca ctatttaatg atgggtaaga acccagttgg
     3001 ctcaaccagc tagcgtaagg attcgctgtg aataatgctg acagacgcag cggtcccgcc
     3061 gggacagttg cttaagcttt aatgggaact caatcaaagg ctcatcgatt cattctttct
     3121 agctgaagtt ttagaaaatt acttattaat tacttctttt actttggtct tagtttttta
     3181 gcctaaagaa cattttgatt ggcttgtgct gatctcacca tgcttcctgg acaatgtttc
     3241 tgcttctaag ttgagtgtct tctcttgtct acctagttat gtgtgaagtg tgcagaattc
     3301 agggaagctt agactttttc atactaagtt agggatagtt tcatgatagt gtgtaaatat
     3361 agcaaccaaa aattaattgt tcacgtgtca tctaagcaag gtaaactcat agtgaggtga
     3421 tgaatgttgc tgacagtagg aggtggtggt cagggagcca cagggctgtt ctcataaagt
     3481 gaacgtgcct gtcggcttga tcacccccaa gtgtggtctc agtggacatc agtaaacaga
     3541 tgattgaaag cgtcttctcc ataggtatga atctcactga tgcttttgag tgtgtgtagt
     3601 gttatgtgag ggtgaagagt gggtacccta aagagcgtct gcagtcagac ctgacacttt
     3661 cacactttaa tcctaggaat gactgtgata agcaggagaa cctccgagaa ggaaggcttc
     3721 ctcagtgtag atacaaactt ctgggtgccg aagggatgga gacttgaagt gggtaaacct
     3781 gtttcagctc tgagatttat atgctccaag catttactta aaattcagaa gccagaagtt
     3841 ccagatcatg acttctagga agctaggcca gaatgagtcc ccagatagct gggccaagcc
     3901 tgaccatagg tgcggttgga tgagtctggc ctgagagtca gcgctgttgc cttattcctc
     3961 attcaggcat attgtccaga cccgctgcta gctagcctag cttgcatgtt tacagtgtct
     4021 tctggaacct tagtgtgact gaaagagacg ttggagatac ttcttgctaa gttggcagaa
     4081 tccagaagac cttatcaggc catttggtcc atctgtatac acaccccacc ccctcacccc
     4141 agtggtcaaa gggtctggga agagcagccc agagtttgtc atgcagcgtt gtctgggtgt
     4201 caccgatgag tgacactgct ctttttgttg tagttaacat tatgtctttg aatgggtgaa
     4261 caccccagct gatcccccag tccctctcag gctgccttgt tccctgttgt tacctctctg
     4321 gggccccgct tgatctactt gactttgagt gctaaatctc aagtggccat cagtatcagg
     4381 aaaggcatac cctgcaggct ccgtccggac tgtccacagc tagccctgga cagtgatgtt
     4441 cattccaaac ccgtcaaggc cttagcccag gcttggctta gatacctagg accagagttt
     4501 gcatatgcaa acattggtta tatctgtggc ctggatcttc ttgtgggaat taattataaa
     4561 tgccattgaa tccactagta aataatcttt gtaaaccatg cagctttatt gctctcttcc
     4621 cccaaagaat gtcgtttgaa attttctcat ttcagtagta gaggccgtaa ctgccattgt
     4681 aacactgata atgcaacatg aaactcaagg tgcctacctg ctcatacagc ggagtcggcc
     4741 atcatactgc aactcagagg gaagagaagg aagggcacgg gcacaggagg accctgcgag
     4801 tcaggcactg aggggtcaca gcctgcgtcg tcctgtgtcc tcgtggcaca cctactgagg
     4861 accatgtgtc tcttcctgcc tgactttgtt gttcttcagt accagcattg cccgccctgt
     4921 tcaagaatcc agaatgctcc ggtctgagca gagcacctta cagtgggctt tgaaggccac
     4981 tcacgaggag agtttccatg aggaccaggg cctccaggag cctgtggggt ttaggtttgg
     5041 ggttgttttg ttgttttttt atttcaagtt tcagcaggag agatgtgcaa tgtttcaata
     5101 ggattccgat ttgacttcac tctttcaaac gctgcaatgc aatacagatc actttgaagt
     5161 ggggaaaaat gcaaagttgt gtttcccttt tatctgtgaa tctttaagac acgtgttgtt
     5221 gctgtacgtg ctgagtggtc ttattctcta ctgcttcggc gtggggctcc catgacgtca
     5281 ttgcaccggg ctctcagccc ttccggggag gcaagaagcc ccgcgccacc tcgagcgaag
     5341 cttttgttcc gtgagcgcag taccacctca ttaacctttt tagtggtgtg gattttatac
     5401 catctgtgta tgtttgcaaa tattaagtta ttacatgttt caaaatgagc atttttcatc
     5461 ctaaatttta tatgtttgca aatatatttt tttaataaaa tttcaaaacc aagttttagc
     5521 accta
//
