LOCUS       NM_001357165           11204 bp    mRNA    linear   ROD 26-JUL-2022
DEFINITION  Mus musculus dachsous cadherin related 2 (Dchs2), mRNA.
ACCESSION   NM_001357165
VERSION     NM_001357165.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 11204)
  AUTHORS   Sai X, Ikawa Y, Nishimura H, Mizuno K, Kajikawa E, Katoh TA, Kimura
            T, Shiratori H, Takaoka K, Hamada H and Minegishi K.
  TITLE     Planar cell polarity-dependent asymmetric organization of
            microtubules for polarized positioning of the basal body in node
            cells
  JOURNAL   Development 149 (9) (2022)
   PUBMED   35420656
REFERENCE   2  (bases 1 to 11204)
  AUTHORS   Bagherie-Lachidan M, Reginensi A, Pan Q, Zaveri HP, Scott DA,
            Blencowe BJ, Helmbacher F and McNeill H.
  TITLE     Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the
            nephron progenitor pool
  JOURNAL   Development 142 (15), 2564-2573 (2015)
   PUBMED   26116661
REFERENCE   3  (bases 1 to 11204)
  AUTHORS   Mao Y, Mulvaney J, Zakaria S, Yu T, Morgan KM, Allen S, Basson MA,
            Francis-West P and Irvine KD.
  TITLE     Characterization of a Dchs1 mutant mouse reveals requirements for
            Dchs1-Fat4 signaling during mammalian development
  JOURNAL   Development 138 (5), 947-957 (2011)
   PUBMED   21303848
REFERENCE   4  (bases 1 to 11204)
  AUTHORS   Rock R, Schrauth S and Gessler M.
  TITLE     Expression of mouse dchs1, fjx1, and fat-j suggests conservation of
            the planar cell polarity pathway identified in Drosophila
  JOURNAL   Dev Dyn 234 (3), 747-755 (2005)
   PUBMED   16059920
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC138394.7 and AC107700.12.
            
            On Jun 20, 2019 this sequence version replaced NM_001357165.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN01164137,
                              SAMN01164138 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2416              AC138394.7         202758-205173
            2417-2608           AC107700.12        2711-2902
            2609-2840           AC107700.12        12388-12619
            2841-3077           AC107700.12        33023-33259
            3078-4088           AC107700.12        34165-35175
            4089-4276           AC107700.12        37598-37785
            4277-4376           AC107700.12        38924-39023
            4377-4531           AC107700.12        44071-44225
            4532-5375           AC107700.12        45308-46151
            5376-5615           AC107700.12        49071-49310
            5616-5750           AC107700.12        64285-64419
            5751-5960           AC107700.12        64838-65047
            5961-6818           AC107700.12        68302-69159
            6819-6932           AC107700.12        80356-80469
            6933-7144           AC107700.12        89088-89299
            7145-7296           AC107700.12        90997-91148
            7297-7427           AC107700.12        110027-110157
            7428-7714           AC107700.12        111872-112158
            7715-7847           AC107700.12        115559-115691
            7848-11204          AC107700.12        117720-121076
FEATURES             Location/Qualifiers
     source          1..11204
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3"
     gene            1..11204
                     /gene="Dchs2"
                     /gene_synonym="EG627094; Gm417; Gm6731"
                     /note="dachsous cadherin related 2"
                     /db_xref="GeneID:100534287"
                     /db_xref="MGI:MGI:2685263"
     exon            1..2416
                     /gene="Dchs2"
                     /gene_synonym="EG627094; Gm417; Gm6731"
                     /inference="alignment:Splign:2.1.0"
     CDS             422..10462
                     /gene="Dchs2"
                     /gene_synonym="EG627094; Gm417; Gm6731"
                     /note="dachsous 2; protocadherin alpha 5"
                     /codon_start=1
                     /product="protocadherin-23"
                     /protein_id="NP_001344094.1"
                     /db_xref="CCDS:CCDS89642.1"
                     /db_xref="GeneID:100534287"
                     /db_xref="MGI:MGI:2685263"
                     /translation="MSPAGRRMGEGRQPAGSPRGRPRGAGAQSSLLRLFVHAWLWAAS
                     GSSAQVFNLSLSVDEGLPPDTLVGDIRAGLPAAQQQDGNGFFLSEDSDDSPLLDDFHV
                     HPDTGIIRTARRLDRERQDHYSFVAATLLGEVVQVEIRVNDVNDHSPRFPRDSLQLDV
                     SELSPPGTAFRLPGAQDPDAGLFSIQGYTLLQASDMPQDPTGPFFQLRYGTPGLPASP
                     SLPVSSSPLEPLDLVLLRRLDREAAAAHELHIEAWDGGSPRRTGLLHVQLRVLDENDN
                     PPVFEQGEYRATVREDAQPGSEVCRVRATDRDLGPNGLVRYSIRERQVPVASAGGGPL
                     GDPGYFSVEELSGVVRVQRPLDREEQAWHQLVVQARDGGAEPEVATVRVSIDVLDVND
                     NPPAIHLLFLTEGGAVQVSEGAHPGDYVARVSVSDADGDPEKEEEAAGVLGARLLGAG
                     SIKLSLESGNGVFALRPGGPPGVFFLCIEGLLDRESQDLYELRLVATDAGSPPLSTEE
                     SLLLWVSDLNDQPPVFSQEHYWASVSEAAVPGTSVVWVSALDADQAGTDHAKLRYELV
                     QLSDPCQSEALSPEEECVPSFSINPDNGLISTIRALDREVQETVELRVVAQDLGEPPL
                     SATCLVTITVDDVNDNEPVFRRQVYNVTLAEHAAVGHCFLQVKASDADAGLYGLVKYS
                     LYDGFQSYEAPPAFQIDPQDGRICVSQDIDRERDPGTFDLLVKAKDGGGLSAQAFVRV
                     EVDDVNDNYPVFTPSTYVTSISGQTPPGTEIINVLASDRDSGIYGTVAYELIPGDQSS
                     LFTIDSTTGIIYLTSTLSHLEATTIFLMVCARDGGGLTAATNADVTIHIMQTTLAPAE
                     FERPKYTFSVYEDVPEDTLVGTVKARESLNSSEPITYRISSGDPEGKFSIHRWLGSIR
                     TLKPLDHEAQPMVVLTVQAQLGSSPACSSTEVNITVMDVNDNRPEFPTASDEIRISQT
                     TPPGTALYLARAQDRDSGLNGLVRYSIASPQPSEFSMDQGRGVLYLRESLGSKADFRL
                     ILVAKDQGVPPQVSQLVLTVVIESQERIPAVAFENLVYQVEVSESLPLTTQILQVQAY
                     PLYPWRPTSKTFYSLDVSVDSAVFGIHPHTGWIYLRRQLDYEFTQTYKFRVYVHTSED
                     RLLQNVSTSVIVHVLDENDHSPAFLQNRVFLNVEESPIPLGVIGKMTAIDADSGKNGQ
                     LSYFLLTDGKFFKMNPNTGELINWLALDREHQGHHQITVLVTDHGSPPRNATMLVYVT
                     ITDINDNWPFFPQCLPGKEFHFKVLEGQPVNTLVTTVFAKDLDEGLSAELTYSISSDY
                     PAHFKIDANNGEIRTTSILSHDYRPSYRMTVIASDHGVPPLQGKAIINIQVIPLSKGR
                     VLMSQNIRHLVIPENTKPSKIMSLMKSPDPLQQDHGGKLHFSIAAEDKDDHFEIDSST
                     GDLFLTKELDYEMTSHYLIRVISKDHSQSPAWNSTVFLSIDVEDQNEHSPSFQDEFIV
                     ISIEENVPVGTLVYVFNAKDGDGSFLNSRIQYFAESSSVGVNPFLIHPSSGALVTASP
                     LDRENVPTFILTVTASDQAVNVTDRRWRTLVAEVVILDVNDHSPTFVSYPITYVREDA
                     EVGAVVHRITAQDPDAEMNGEVAYSILSGNEDMVFVLDSSSGLLRIACPLDYEVKTQH
                     ILTLVAHDGGMPARSSSQTLTITVLDVNDETPAFKQLLYETSVKENQSPGVFVTRVEA
                     EDTDSGVNSKHQFEIMPGPAFGLFEINPDTGEVVTAVTFDREAQGIFRLRVLVRDGGV
                     PSLSSTADIICTIEDENDHAPEFIVLHHDIEILENRDPEVVYTVLAFDMDAGNNGAVT
                     YHIAEGNTDEYFAIHTTSGELSTTRALDRELISNFTLTILCSDLGNPPRSSAMQLHVR
                     VLDDNDHSPAFPMLHYQSSIREDAEVGTVVLVLSAVDRDEGLNGQVEYFLMEEVSGAF
                     TIDRVTGILRTSHALDRESRSQHTFQAVARDCSTQGAKSSVLSILISVTDANDNDPVW
                     EENPVDAFISPMLALNQTVVHLRASDPDAGPNGTVTFSFADRQSVFSIDGYTGEVKLQ
                     QNLSSEHFPIWLQLLATDQGTPARTTMGLLVVHKEGEGMKLSFSRYLYTGLVTENCEP
                     GTSVVTVKAFAPVSSPDAITYSVVSGNEDGVFSLGSNSGQLIVEEPGLLDFEVRSEVR
                     LIILAESNGHQAFTQVTVAIQDWNDNPPRFAQSVYQASVSEGQFYSVHVIQVSATDLD
                     QGLNSQIEYSIVSGNQAGAFRIDELNGVILTNSILDYESSGSYSLIVQATDRGVPRLS
                     GTALVKIQVTDINDNAPVFLPSEAVEIAENSLPGVIVARVSVHDADLNPAFTFSLVKE
                     SSSAAKFAISQDTGVVVLAQTLDFEEVTEYELIVRVSDSVHHTEGSVIIRVLDVNDNP
                     PVFTQDFYQAAVPELTPGGYLVLTLSATDLESSGDISYRILSPPEGFTIDPRNGTIFT
                     TNSVSVLEKIPTLRFLVEANDGGIPSLTALTLVEIEIQDVNNYAPEFPAGCYNLSLSE
                     DTPIGSTLMTFSTIDGDYSFENTHTEYSIISGNLHNYFHIETSLLGSEHPHQQRGALV
                     LLHALDREASASHKLVILASDHGCPPLSSTSVIAIDILDINDNAPTFSSRHYQAHVKE
                     STPVGSHITMVSADDPDKGSHAEIIYGIISGNEKEHFYLEDRTGVLYLVKPLDYEETV
                     AFTLTIQATDEEEKHVSFAAVHISVLDDNDHSPQFLSSTLACITPENLPPLSIICSVH
                     ALDFDTGPYGEVTYSIVSPCLVTHGMHPYQDLFAIDPLTGDIHTEQMLDYESVREYCL
                     LVQAKDRGDASASLEVWVEVEGIDEFEPIFTQDQYFFSLREKGQGQQLIGRVEASDAD
                     AGVDGEVLYSLRTPSTVFSVNKTNGNIYWVRAPLLGSSQLVKEDTLEVKIIAHSPKPG
                     SKSTSCSVFVNVSLPAEGHHRTVLVHSFSISLVVSLLVFLSLVCTLIVLILRHKQKDP
                     LHSYEEKKTPSSPDADPKLTGAASELKAGQETAEYRGVTGPGEVMPAEWLNLMSVMEK
                     DIIHLFRHSNYSGHCSVDGETAEDKEIQRINENPYRKDSDYALSDQGSRVPDSGIPRD
                     SDQLSCLSGETDVMTSSEVMEASHMFEEGVGGEGCDVIYVQNNALSLRREATAGVLAE
                     SRRESFTSGSQEGRCVAPSTQMTSSDDVRGSYAWDYFLSWEPKFQHLASVFNDIARLK
                     DEHMQVPGIPKDTSFVFPPPLITAVAQPGIKAVPPRMPAITLGQVLPKFPRSPLPYHG
                     GSLPEVMTPNFSPSLSLLTMQTPARSPMLPDGESRGTHMLGPWHDRKAEDEVQG"
     exon            2417..2608
                     /gene="Dchs2"
                     /gene_synonym="EG627094; Gm417; Gm6731"
                     /inference="alignment:Splign:2.1.0"
     exon            2609..2840
                     /gene="Dchs2"
                     /gene_synonym="EG627094; Gm417; Gm6731"
                     /inference="alignment:Splign:2.1.0"
     exon            2841..3077
                     /gene="Dchs2"
                     /gene_synonym="EG627094; Gm417; Gm6731"
                     /inference="alignment:Splign:2.1.0"
     exon            3078..4088
                     /gene="Dchs2"
                     /gene_synonym="EG627094; Gm417; Gm6731"
                     /inference="alignment:Splign:2.1.0"
     exon            4089..4276
                     /gene="Dchs2"
                     /gene_synonym="EG627094; Gm417; Gm6731"
                     /inference="alignment:Splign:2.1.0"
     exon            4277..4376
                     /gene="Dchs2"
                     /gene_synonym="EG627094; Gm417; Gm6731"
                     /inference="alignment:Splign:2.1.0"
     exon            4377..4531
                     /gene="Dchs2"
                     /gene_synonym="EG627094; Gm417; Gm6731"
                     /inference="alignment:Splign:2.1.0"
     exon            4532..5375
                     /gene="Dchs2"
                     /gene_synonym="EG627094; Gm417; Gm6731"
                     /inference="alignment:Splign:2.1.0"
     exon            5376..5615
                     /gene="Dchs2"
                     /gene_synonym="EG627094; Gm417; Gm6731"
                     /inference="alignment:Splign:2.1.0"
     exon            5616..5750
                     /gene="Dchs2"
                     /gene_synonym="EG627094; Gm417; Gm6731"
                     /inference="alignment:Splign:2.1.0"
     exon            5751..5960
                     /gene="Dchs2"
                     /gene_synonym="EG627094; Gm417; Gm6731"
                     /inference="alignment:Splign:2.1.0"
     exon            5961..6818
                     /gene="Dchs2"
                     /gene_synonym="EG627094; Gm417; Gm6731"
                     /inference="alignment:Splign:2.1.0"
     exon            6819..6932
                     /gene="Dchs2"
                     /gene_synonym="EG627094; Gm417; Gm6731"
                     /inference="alignment:Splign:2.1.0"
     exon            6933..7144
                     /gene="Dchs2"
                     /gene_synonym="EG627094; Gm417; Gm6731"
                     /inference="alignment:Splign:2.1.0"
     exon            7145..7296
                     /gene="Dchs2"
                     /gene_synonym="EG627094; Gm417; Gm6731"
                     /inference="alignment:Splign:2.1.0"
     exon            7297..7427
                     /gene="Dchs2"
                     /gene_synonym="EG627094; Gm417; Gm6731"
                     /inference="alignment:Splign:2.1.0"
     exon            7428..7714
                     /gene="Dchs2"
                     /gene_synonym="EG627094; Gm417; Gm6731"
                     /inference="alignment:Splign:2.1.0"
     exon            7715..7847
                     /gene="Dchs2"
                     /gene_synonym="EG627094; Gm417; Gm6731"
                     /inference="alignment:Splign:2.1.0"
     exon            7848..11204
                     /gene="Dchs2"
                     /gene_synonym="EG627094; Gm417; Gm6731"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccggccgga tccccttcct ctccgtgtgc gcgctttaaa taatttcctc ctttttggca
       61 aaagaaataa tgcacctgac tttaccaggg ggaaacagcc agccgagcag aacaaggaac
      121 agatgtaaaa ggaatagaag aagagagaaa aagcgatggg actcccttaa agacatccag
      181 aggctggaga ggtggccgcg gaggcagagg cagctagagc cgcccccgcc tgcgtgagct
      241 gcggccagag gacgtctgca ccagttgcag atgccacctt gggaactccc gggtcttttc
      301 gtttgtttgc caaagtcttt tcttccctgg cttaatactg aagaggctcc tgggttgctc
      361 tgagatccca atacaagctg gcagctagcc ggagccttct tcctaaagag ctggaggaga
      421 aatgagccct gctgggcgaa ggatgggtga agggcgtcag ccggctgggt caccccgtgg
      481 gcggccccgc ggcgccgggg cgcagagctc cctgctccgg cttttcgtcc acgcctggct
      541 gtgggcagcc tcgggctcat ctgcccaggt gttcaacctc agcctctcgg tggacgaggg
      601 gctgccccca gacacactgg tgggtgacat tcgcgcgggg ttgccagcag ctcagcaaca
      661 ggatgggaat ggcttttttc tttcggagga ctcggatgac tccccgctgc tggacgactt
      721 ccacgtgcac ccggacactg gtatcatccg caccgctcgg cgtctggacc gcgagcgaca
      781 ggaccactat agcttcgtgg ccgccacgct gttgggagag gtggtacagg tggagatccg
      841 cgtcaacgac gtgaacgacc attcccctcg ctttccccgc gactccctgc agctggacgt
      901 gtccgaactc agcccgcccg ggacagcgtt ccgcctgcca ggagcccagg acccggacgc
      961 gggactgttc agcatccagg gctacacttt gctgcaagct tctgacatgc cccaggatcc
     1021 cacaggaccc ttcttccaat tgcgctatgg gacgccgggg ttaccggcgt cgccttccct
     1081 gccggtgtcc tcatcaccgc tggaaccctt agacttggtg ctgctgcggc gcttggaccg
     1141 agaggcggcg gcagcgcacg agctgcacat tgaagcttgg gacggtggca gccctcggcg
     1201 caccggcctc ctgcacgtgc agctgcgtgt gttggatgag aacgacaacc cgccagtttt
     1261 cgagcagggc gagtaccgcg ccacagtacg tgaggacgcc cagccgggct ctgaggtttg
     1321 tcgcgtgcgt gctactgatc gcgacttggg ccccaatggc ttggtacgct acagtatccg
     1381 ggagcggcaa gtgcccgtgg cgagcgcagg tggtgggcca ctgggcgatc cgggttattt
     1441 ttctgtggag gagctgagcg gcgtagtgcg ggtgcaaaga cctttagacc gggaggagca
     1501 ggcctggcac cagttggtgg tccaggcccg cgacgggggc gccgagccag aggtagccac
     1561 cgtgcgcgtg tccattgacg tgctggacgt gaatgacaac cctcctgcca tccacctgct
     1621 cttcctcacc gagggaggtg cggtccaggt ctctgagggc gcccacccag gcgactacgt
     1681 ggctcgagtc tcagtgtccg atgccgacgg tgacccagag aaagaagagg aggctgcagg
     1741 ggtgcttggt gcacgcctcc ttggggcggg cagtataaag ttgtccttgg aaagtgggaa
     1801 cggagtcttt gcgctgcggc ccggtggtcc acctggagta tttttccttt gcatcgaggg
     1861 cctcttggac agggaaagcc aagatctata cgagttaaga ctagtggcca ctgatgcagg
     1921 gtccccgcca ttgagcacgg aggagtcgct gttgctctgg gtctcggacc tcaatgacca
     1981 gccacctgtc tttagccagg agcattactg ggcctccgtg tctgaagccg ctgtccctgg
     2041 cacctcggtg gtttgggtca gcgctttaga tgctgaccag gcgggcactg atcacgccaa
     2101 gctgcgatat gagctagtgc aactctcaga tccctgccag tctgaggctc tgtcacccga
     2161 ggaagagtgt gtgccatcct tcagcatcaa tcccgacaac ggtttgatca gcaccatccg
     2221 agctctagac agagaggtcc aggagacagt ggagctgaga gtggtggccc aggaccttgg
     2281 agagccgcca ctttctgcca cctgtctggt gaccattaca gtggatgatg tgaatgacaa
     2341 tgagcccgtt ttccggaggc aggtgtataa tgtcactctc gcggagcatg ctgcagttgg
     2401 acattgcttt ctgcaggtaa aagcctcaga tgcagatgca ggactctacg gcttagtcaa
     2461 gtattctctt tatgatggat tccaaagtta cgaagcacct ccagcattcc agatcgaccc
     2521 acaggatggc cgcatctgtg tgtcccaaga catagacagg gaaagggatc cgggcacctt
     2581 tgatctgctg gtaaaagcta aggatggggg tggtctcagt gcccaggcgt ttgtccgggt
     2641 agaagtggat gacgtgaatg ataattaccc tgtcttcaca ccatcgactt atgtgacaag
     2701 catcagtggc cagaccccac cgggaactga gatcatcaac gtccttgcca gtgacagaga
     2761 ttctggaata tatggaacag tggcttatga actcatccca ggagatcagt cgtctctctt
     2821 caccattgac tccactacag ggattattta cttaacatca actctcagcc atttggaagc
     2881 caccaccatt tttctgatgg tctgtgctcg agacggtggt gggctcacag ctgccactaa
     2941 cgctgatgtc accatccaca tcatgcagac cacgctggct cctgcggagt ttgaaaggcc
     3001 caagtacacc ttctcagttt atgaagacgt gccagaagat acgctcgttg ggacagtgaa
     3061 ggcgagagag tccttgaatt cctcagagcc aatcacgtat cgaatttcct ctggcgatcc
     3121 ggaaggaaag ttctccattc acagatggct gggcagtatc cgcaccctga agcctctgga
     3181 ccacgaagca cagcccatgg ttgttctcac ggtccaggca cagctcggca gctccccagc
     3241 ctgcagcagt acagaagtga acataacagt gatggatgtc aatgacaacc gccctgagtt
     3301 tcccacagcc tcagatgaaa ttaggatctc ccagaccact ccgcctggta cagccttgta
     3361 ccttgcacgt gcgcaggata gagacagcgg gctgaatgga ctggtccggt acagcatcgc
     3421 aagcccccaa ccaagcgaat tcagcatgga ccaaggccgt ggggtgctgt acctcaggga
     3481 gagtctggga agcaaggcgg acttcaggct gattctcgtg gctaaggatc aaggtgttcc
     3541 tccccaggta tcccagttgg tactcacagt agttattgaa agccaagaac gaatcccagc
     3601 cgtggctttt gaaaatttgg tctatcaagt agaagttagt gagtctctcc cactgaccac
     3661 tcaaatccta caggtacagg cctacccact gtatccctgg cgcccaacct cgaagacatt
     3721 ttactccctg gatgtcagcg tggactctgc agtgtttgga atccaccctc acactgggtg
     3781 gatttatcta cggcgacagc tagactatga gtttacacag acatacaagt ttagagtgta
     3841 tgtgcacacc tcagaggacc gattgctgca gaatgtgagc acttcggtga tagttcatgt
     3901 cttggatgag aacgaccact ccccagcctt cctgcagaac agggtgtttt tgaacgttga
     3961 ggagagccct atccccctag gggtaatagg gaaaatgaca gccatcgatg ctgactctgg
     4021 gaagaacgga cagctctcct atttcctttt gaccgatgga aaattcttca agatgaatcc
     4081 taacacaggt gagctgatca attggttggc actggatcgt gaacatcagg ggcatcatca
     4141 aataactgtc ctagtgacag accacggctc cccaccacgg aatgccacca tgctggttta
     4201 tgtcacaatt actgacatca atgacaactg gccttttttc cctcagtgtc tcccgggaaa
     4261 ggaatttcac ttcaaggttt tggaaggtca gccagtcaat acactggtta caactgtctt
     4321 tgcaaaggat ctcgacgaag gactcagtgc agaacttacg tactccatct cttcagatta
     4381 tcctgctcac tttaagattg atgcaaacaa cggtgaaata agaacgacct cgatcctttc
     4441 acatgactac agaccttcct ataggatgac agttatcgcc agtgaccatg gggtgccccc
     4501 acttcaagga aaggcaatta ttaatattca ggtgatacca ctctccaaag ggagagttct
     4561 tatgtctcag aatatccgac atttagttat cccggaaaac acgaagcctt caaagatcat
     4621 gagcctgatg aagtcaccgg atccccttca acaggaccat ggtgggaagt tacacttcag
     4681 cattgctgca gaggacaagg acgaccactt tgaaattgac agctcgacag gagatttgtt
     4741 cctaactaag gaacttgact acgaaatgac atcccattat cttatcaggg tgatttctaa
     4801 agatcacagc caaagccctg cctggaacag cacagtcttc cttagcattg atgtggaaga
     4861 ccaaaatgag cattctccat ccttccagga tgagttcatt gtgataagca tagaggagaa
     4921 tgtccctgta gggactctgg tgtatgtctt caatgccaaa gatggcgatg gcagttttct
     4981 gaacagtagg atacaatact ttgcagaatc cagctctgtt ggagtgaacc catttctcat
     5041 ccacccctcc tctggtgcat tggtcactgc atctcccctg gatcgagaaa atgttccaac
     5101 gttcatctta actgtcacgg catcagatca ggccgtgaat gtgacagatc ggcgatggag
     5161 gaccctggta gcagaagtgg tgattttgga tgtgaatgac cacagcccca cctttgtgtc
     5221 ctatcccatc acctatgtga gagaggatgc tgaagtaggt gctgtggtgc accgcataac
     5281 tgcccaggat ccagatgcag agatgaatgg agaagtagct tacagcatcc tctcaggaaa
     5341 tgaggacatg gtcttcgtgc tagacagctc ctcaggcttg ctgaggatag cctgcccttt
     5401 ggattatgaa gtgaaaactc agcatatcct gaccctcgtg gcccatgatg gtggcatgcc
     5461 agcacgctct tcatcccaga ctctgacaat cactgtcctt gatgtaaatg atgagacacc
     5521 agcatttaag caacttctgt atgaaacttc agttaaagaa aaccaaagtc caggggtgtt
     5581 tgttacaagg gttgaagctg aagacacgga ttcaggagtc aattccaaac atcagtttga
     5641 aatcatgcca gggcctgcct ttgggttgtt tgagatcaat cctgacactg gagaggtggt
     5701 gacagctgtc acgtttgaca gggaagctca aggaatcttc aggcttcgag tactagtgcg
     5761 agatggcggt gtcccttcat tatccagcac tgcggacatc atctgcacca ttgaagatga
     5821 aaatgaccat gccccggagt ttattgtcct ccatcatgac attgaaatcc tagaaaaccg
     5881 agatccagag gttgtgtaca ctgtgttggc ttttgatatg gatgctggca acaatggagc
     5941 tgtcacctat cacatagctg aaggaaatac cgatgagtat tttgcaatcc atacaacctc
     6001 aggagaactc tcaacaactc gtgctttgga ccgggagctg atcagcaatt ttaccctcac
     6061 tatcctgtgc tcagacttgg ggaacccgcc tcgaagctct gcaatgcagc tgcatgttag
     6121 agttctggat gacaacgacc acagccccgc ttttcctatg cttcattatc agtcctccat
     6181 aagagaagat gccgaggtgg gcaccgtggt tctggtgctg tctgccgtgg acagagatga
     6241 gggtctcaac gggcaggtgg aatattttct tatggaggaa gtttccggtg ccttcactat
     6301 tgatcgtgta acagggatct tgagaactag ccatgccctt gatcgagaat ccaggtctca
     6361 gcacacattc caggctgtag ccagagactg cagcactcaa ggtgccaaaa gcagcgtgct
     6421 ctccatactc atatccgtca cggatgctaa cgacaacgat cctgtttggg aagagaaccc
     6481 agttgatgct ttcatctccc caatgctggc cctaaaccag accgttgttc atctgagagc
     6541 cagtgaccca gatgcagggc ccaatggaac tgttacgttt agttttgcag accgccagtc
     6601 cgtgttttcc atcgatggat atacaggaga agttaaactg cagcagaatc tgtcttcaga
     6661 acactttcct atctggttgc agttattggc cacagatcaa gggaccccgg caaggacaac
     6721 catgggtctc ttggttgtcc acaaggaagg agaaggtatg aagctgtcct tcagccgcta
     6781 tctctacaca ggactcgtga ctgaaaactg tgagccaggt acttctgttg tgactgtaaa
     6841 ggcgtttgct cctgtgtcaa gtccagacgc cattacatac tcagttgtta gtgggaatga
     6901 agatggagtg ttctcccttg gctccaactc agggcaactc atcgtagaag agcctggatt
     6961 gcttgatttt gaagtcagga gtgaagtgcg gctcatcatt cttgctgaaa gcaatgggca
     7021 tcaagccttc acccaagtca cagttgccat ccaggactgg aatgataatc ctccacgttt
     7081 tgcacaaagt gtataccaag catcagtgtc tgaaggacag ttctacagtg ttcatgtcat
     7141 acaggtgtca gctactgact tggaccaggg cttgaacagc cagatcgagt attccattgt
     7201 ctctggcaac caagcgggag ccttccggat cgacgagctg aatggagtga tcctgaccaa
     7261 ctccatcctg gactacgagt cctccggctc ctacagcttg attgtgcaag ccacagacag
     7321 aggggtgccc aggctttctg gtacagctct ggtcaagata caggtgactg atataaacga
     7381 caatgctccg gtctttctcc cctcagaagc agtagaaatt gcagaaaatt ctttgcctgg
     7441 tgtaattgtg gctcgggtat ccgtccatga tgcggatctg aatccagctt tcaccttcag
     7501 tcttgtcaaa gaaagcagct ctgcagccaa gtttgctatc agtcaggaca ctggagtggt
     7561 ggtgctggcg caaacactgg attttgaaga agttaccgaa tacgagctga tcgtccgtgt
     7621 ttctgattca gtgcaccaca cagagggttc cgtcatcatc cgtgtgctgg atgtcaatga
     7681 taatccacca gtttttactc aagatttcta ccaggctgca gttcctgaac tcacacctgg
     7741 agggtacttg gtgctgaccc tgtctgccac cgacttagaa agcagtggag acatttctta
     7801 ccggatcctt tcccctcctg agggattcac catcgacccc aggaatggca ccatattcac
     7861 tactaattct gtatcagttc tggaaaaaat accgacactt cggtttcttg ttgaagccaa
     7921 tgatggtgga attccctcct tgacggctct cacattagtg gagatagaaa tacaagatgt
     7981 aaacaactat gcccccgagt ttccagcagg gtgctataat cttagcttga gtgaagatac
     8041 acccatcgga agtaccctca tgacattttc aactattgac ggtgactact ctttcgaaaa
     8101 cacacacacc gagtattcta tcatcagcgg caacttacac aactacttcc acatcgaaac
     8161 cagcctactt ggttcagaac atccccacca gcagaggggt gctcttgtgt tgcttcatgc
     8221 tctggacaga gaagctagtg ccagccacaa gcttgtgatt cttgcgtctg accacggctg
     8281 ccctccactg agttccacaa gtgtcatagc aatagacatt cttgatatca atgacaatgc
     8341 acccaccttc agcagtcgac actaccaagc ccatgtcaag gaaagcaccc cggtggggag
     8401 tcacatcacc atggtatcgg cagatgaccc tgacaaaggt tcacatgcag aaatcatcta
     8461 tggcataatc tctggaaatg aaaaagaaca tttttactta gaagacagaa ctggggttct
     8521 ttatttggtg aaacctctgg attacgagga aacagtagcc ttcactctaa ccatccaagc
     8581 tacagatgag gaggagaaac acgtctcttt tgctgctgtg catatcagtg tgttagatga
     8641 caatgaccac tcacctcagt ttctgtcctc taccttggcc tgcatcactc ctgaaaacct
     8701 gcctcctctc tccatcatat gttctgtgca cgctctggat tttgacaccg ggccttacgg
     8761 agaggtgact tactctattg tgtcaccctg ccttgtcaca cacgggatgc atccttatca
     8821 ggatctcttt gccattgatc ctttgacagg ggacattcac actgagcaaa tgcttgacta
     8881 tgagagtgtc agggagtact gcctcctggt tcaggccaaa gacagaggtg atgcctcagc
     8941 ttctctggag gtttgggtgg aagttgaagg gatagacgag tttgaaccca tttttactca
     9001 agaccaatat tttttcagtc tccgtgagaa gggtcaagga cagcagctga ttggcagagt
     9061 agaggcctcg gacgcggatg ctggggtgga tggggaagtg ctctactctc ttaggactcc
     9121 atccactgtc ttctcggtca acaaaacgaa tggcaacatt tactgggtta gagctcctct
     9181 cctaggaagc agtcagctcg tcaaagaaga cactctggaa gtgaaaataa ttgctcatag
     9241 ccccaaaccc ggctccaaat ccacatcctg cagcgtgttt gtgaatgtct ctttgccagc
     9301 tgaaggacac catagaacag tactggttca cagtttctcc atcagccttg tggtctcctt
     9361 gttagtgttc ctctcgcttg tctgcactct aattgtactg attttaaggc ataagcaaaa
     9421 agacccacta cacagctatg aggagaagaa gaccccatca tccccagatg ctgatcccaa
     9481 attgactggg gctgcaagtg agcttaaggc tgggcaggag accgccgagt acaggggtgt
     9541 gacagggcct ggtgaagtca tgcctgctga atggttgaac ttaatgagtg tcatggagaa
     9601 ggacattatc cacctattca ggcactcaaa ctacagtggc cactgctctg tggatggaga
     9661 aactgcagaa gataaagaaa tccagaggat aaatgagaat ccttatagaa aggactcaga
     9721 ctatgccctg agtgaccagg gttccagggt gccggactcg ggcatcccta gggactctga
     9781 ccagctttct tgcctgtcag gagagacaga tgtgatgact agttctgagg taatggaagc
     9841 cagccacatg tttgaggaag gagttggagg ggaaggctgt gacgtaatct atgttcaaaa
     9901 taatgcatta tccctgagaa gagaggcaac agcaggtgtc ttggctgaga gcaggagaga
     9961 gtccttcact tcaggcagtc aggaaggaag atgtgtagct ccttccactc agatgacttc
    10021 ttctgatgat gtcagaggca gctatgcctg ggattacttc ctcagttggg aacccaagtt
    10081 ccagcatctt gcctcagtgt ttaatgatat tgccagacta aaggatgaac atatgcaggt
    10141 gcctggcatt ccaaaagaca cgtcttttgt ttttccaccc cctttgatca cagcagtagc
    10201 gcagccaggg attaaggcag ttcccccacg aatgccagcc atcaccctgg gccaagttct
    10261 tccgaaattc ccccggtctc cccttcccta ccatggcggg tctctaccag aagtcatgac
    10321 tcccaacttc tctccatctc tttccctact gacaatgcag actcctgcca ggtcaccaat
    10381 gttgccagat ggagaatcta gaggaacgca catgcttggc ccatggcatg acaggaaagc
    10441 tgaagatgaa gttcaaggat agacctgatg ctgactccgt gcctgctcgc ccatctctca
    10501 gctcagacat gaaaagactc aagcaagttc agaagggtgg gttcattctt acccaacagc
    10561 agactatctc atgtagccag cgtgtatttc agtttctcaa aactcttcca gccttaatga
    10621 gaagttattt ccttgtctag attttttggg ttactctcag gattcgcgcg cgcgcgtgtg
    10681 tgtgtgtgtg tgtgtggaca ttaactagta tgttttatca ttcctgtttc tttgatgttg
    10741 aaagtttatg atttgaataa gcatcagaaa ttatgattgg aatttttcat gacgctgtgc
    10801 taatatagcc aaaaatgcac tcttgattga atgaagcaga aaaccctttc ttgatgtaag
    10861 gctgcgatgg acaggagaat cttaggcagc tcagcatgtg accaacatga tactctgcct
    10921 tctctccaaa tgatgacccc actggtgctc tgtccagatt aaaaaaaaaa accttcaaag
    10981 attaatttat agaaatcact tcattttatt ttctttaggg atagtgtgac tttgggtgtg
    11041 agataattta tctactcaat gtccactttt gaagtttgtg tagataaaac tacgttacta
    11101 gctaattata aatttcatag agtattttag cagtatattt ttaaatgaag tttttctttt
    11161 atatatatga aagtttctac tattaaagtt aagggtgggt gtca
//
