LOCUS       NM_007831              10325 bp    mRNA    linear   ROD 14-JAN-2025
DEFINITION  Mus musculus DCC netrin 1 receptor (Dcc), mRNA.
ACCESSION   NM_007831
VERSION     NM_007831.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 10325)
  AUTHORS   Dudukcu,O., Raj,D.D.A., van de Haar,L.L., Grossouw,L.M.,
            Linders,L.E., Garritsen,O., Adolfs,Y., van Kronenburg,N.C.H.,
            Broekhoven,M.H., Kapteijns,T.H.W., Meye,F.J. and Pasterkamp,R.J.
  TITLE     Molecular diversity and migration of GABAergic neurons in the
            developing ventral midbrain
  JOURNAL   iScience 27 (11), 111239 (2024)
   PUBMED   39569362
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10325)
  AUTHORS   Hu,Y.Q., Liu,W.T., Wu,Y., Hu,Z.B., Tao,Y.C., Zhang,Q., Chen,J.Y.,
            Li,M., Hu,L. and Ding,Y.Q.
  TITLE     DCC in the cerebral cortex is required for cognitive functions in
            mouse
  JOURNAL   Brain Pathol, e13306 (2024) In press
   PUBMED   39293934
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   3  (bases 1 to 10325)
  AUTHORS   Lo Giudice,Q., Wagener,R.J., Abe,P., Frangeul,L. and Jabaudon,D.
  TITLE     Developmental emergence of first- and higher-order thalamic neuron
            molecular identities
  JOURNAL   Development 151 (18) (2024)
   PUBMED   39348458
REFERENCE   4  (bases 1 to 10325)
  AUTHORS   Curran,B.M., Nickerson,K.R., Yung,A.R., Goodrich,L.V., Jaworski,A.,
            Tessier-Lavigne,M. and Ma,L.
  TITLE     Multiple guidance mechanisms control axon growth to generate
            precise T-shaped bifurcation during dorsal funiculus development in
            the spinal cord
  JOURNAL   Elife 13, 94109 (2024)
   PUBMED   39159057
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 10325)
  AUTHORS   Masuda,A., Nishida,K., Ajima,R., Saga,Y., Bakhtan,M., Klar,A.,
            Hirata,T. and Zhu,Y.
  TITLE     A global gene regulatory program and its region-specific regulator
            partition neurons into commissural and ipsilateral projection types
  JOURNAL   Sci Adv 10 (21), eadk2149 (2024)
   PUBMED   38781326
REFERENCE   6  (bases 1 to 10325)
  AUTHORS   Kavety,B., Jenkins,N.A., Fletcher,C.F., Copeland,N.G. and
            Morgan,J.I.
  TITLE     Genomic structure and mapping of precerebellin and a
            precerebellin-related gene
  JOURNAL   Brain Res Mol Brain Res 27 (1), 152-156 (1994)
   PUBMED   7877445
REFERENCE   7  (bases 1 to 10325)
  AUTHORS   Reale,M.A., Hu,G., Zafar,A.I., Getzenberg,R.H., Levine,S.M. and
            Fearon,E.R.
  TITLE     Expression and alternative splicing of the deleted in colorectal
            cancer (DCC) gene in normal and malignant tissues
  JOURNAL   Cancer Res 54 (16), 4493-4501 (1994)
   PUBMED   8044801
REFERENCE   8  (bases 1 to 10325)
  AUTHORS   Justice,M.J., Gilbert,D.J., Kinzler,K.W., Vogelstein,B.,
            Buchberg,A.M., Ceci,J.D., Matsuda,Y., Chapman,V.M., Patriotis,C.,
            Makris,A. et al.
  TITLE     A molecular genetic linkage map of mouse chromosome 18 reveals
            extensive linkage conservation with human chromosomes 5 and 18
  JOURNAL   Genomics 13 (4), 1281-1288 (1992)
   PUBMED   1354644
REFERENCE   9  (bases 1 to 10325)
  AUTHORS   Moen,C.J., Snoek,M., Hart,A.A. and Demant,P.
  TITLE     Scc-1, a novel colon cancer susceptibility gene in the mouse:
            linkage to CD44 (Ly-24, Pgp-1) on chromosome 2
  JOURNAL   Oncogene 7 (3), 563-566 (1992)
   PUBMED   1347918
REFERENCE   10 (bases 1 to 10325)
  AUTHORS   Fearon,E.R., Cho,K.R., Nigro,J.M., Kern,S.E., Simons,J.W.,
            Ruppert,J.M., Hamilton,S.R., Preisinger,A.C., Thomas,G.,
            Kinzler,K.W. et al.
  TITLE     Identification of a chromosome 18q gene that is altered in
            colorectal cancers
  JOURNAL   Science 247 (4938), 49-56 (1990)
   PUBMED   2294591
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK090377.1, AK157715.1, CN665025.1, AC136637.3 and BQ550935.1.
            
            On Mar 20, 2007 this sequence version replaced NM_007831.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X85788.1, SRR9219382.63268.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMN00849374, SAMN00849379
                                           [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1608              AK090377.1         2-1609
            1609-2655           AK157715.1         1558-2604
            2656-3217           CN665025.1         1-562
            3218-4103           AK157715.1         3107-3992
            4104-4242           AC136637.3         135747-135885       c
            4243-4359           AC136637.3         129379-129495       c
            4360-4521           AC136637.3         114320-114481       c
            4522-4734           AC136637.3         107679-107891       c
            4735-4877           AC136637.3         71155-71297         c
            4878-10035          AC136637.3         62270-67427         c
            10036-10325         BQ550935.1         1-290               c
FEATURES             Location/Qualifiers
     source          1..10325
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 45.24 cM"
     gene            1..10325
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /note="DCC netrin 1 receptor"
                     /db_xref="GeneID:13176"
                     /db_xref="MGI:MGI:94869"
     exon            1..714
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     CDS             624..4967
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /note="netrin receptor DCC; tumor suppressor protein DCC;
                     deleted in colorectal carcinoma"
                     /codon_start=1
                     /product="netrin receptor DCC precursor"
                     /protein_id="NP_031857.2"
                     /db_xref="CCDS:CCDS29336.1"
                     /db_xref="GeneID:13176"
                     /db_xref="MGI:MGI:94869"
                     /translation="MENSLGCVWVPKLAFVLFGASLLSAHLQVTGFQIKPFTSLHFVS
                     EPSDAVTMRGGNVLLNCSAESDRGVPVIKWKKDGLILALGMDDRKQQLPNGSLLIQNI
                     LHSRHHKPDEGLYQCEASLADSGSIISRTAKVTVAGPLRFLSQTESITAFMGDTVLLK
                     CEVIGEPMPTIHWQKNQQDLNPLPGDSRVVVLPSGALQISRLQPGDSGVYRCSARNPA
                     SIRTGNEAEVRILSDPGLHRQLYFLQRPSNVIAIEGKDAVLECCVSGYPPPSFTWLRG
                     EEVIQLRSKKYSLLGGSNLLISNVTDDDSGTYTCVVTYKNENISASAELTVLVPPWFL
                     NHPSNLYAYESMDIEFECAVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRILGVVK
                     SDEGFYQCVAENEAGNAQSSAQLIVPKPAIPSSSILPSAPRDVLPVLVSSRFVRLSWR
                     PPAEAKGNIQTFTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNEW
                     GPGESSQPIKVATQPELQVPGPVENLHAVSTSPTSILITWEPPAYANGPVQGYRLFCT
                     EVSTGKEQNIEVDGLSYKLEGLKKFTEYTLRFLAYNRYGPGVSTDDITVVTLSDVPSA
                     PPQNISLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEMETLEPNNLWYL
                     FTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPENDLDESQVPDQPSSLHVRPQTNC
                     IIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSSHYVISLKA
                     FNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSGPDVSTPMLPPVGVQAVALT
                     HEAVRVSWADNSVPKNQKTSDVRLYTVRWRTSFSASAKYKSEDTTSLSYTATGLKPNT
                     MYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREGKPRAVIVSWQPPLE
                     ANGKITAYILFYTLDKNIPIDDWIMETISGDRLTHQIMDLSLDTMYYFRIQARNVKGV
                     GPLSDPILFRTLKVEHPDKMANDQGRHGDGGYWPVDTNLIDRSTLNEPPIGQMHPPHG
                     SVTPQKNSNLLVITVVTVGVLTVLVVVIVAVICTRRSSAQQRKKRATHSVSKRKGSQK
                     DLRPPDLWIHHEEMEMKNIEKPTGTDPAGRDSPIQSCQDLTPVSHSQSETQMGSKSAS
                     HSGQDTEDAGSSMSTLERSLAARRATRAKLMIPMEAQSSNPAVVSAIPVPTLESAQYP
                     GILPSPTCGYPHPQFTLRPVPFPTLSVDRGFGAGRTQSVSEGPTTQQQPMLPPAQPEH
                     PSSEEAPSRTIPTACVRPTHPLRSFANPLLPPPMSAIEPKVPYTPLLSQPGPTLPKTH
                     VKTASLGLAGKARSPLLPVSVPTAPEVSEESHKPTEDPASVYEQDDLSEQMASLEGLM
                     KQLNAITGSAF"
     exon            715..1035
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1036..1320
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1321..1471
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1472..1608
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1609..1763
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1764..1884
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1885..2041
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2042..2196
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2197..2345
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2346..2484
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2485..2534
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2535..2676
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2677..2787
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2788..2982
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2983..3078
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            3079..3311
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            3312..3450
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            3451..3558
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            3559..3753
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            3754..3786
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            3787..3852
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            3853..4015
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            4016..4242
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            4243..4359
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            4360..4521
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            4522..4734
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            4735..4877
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            4878..10325
                     /gene="Dcc"
                     /gene_synonym="C030036D22Rik; Igdcc1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aatggatagt aaggttccaa ctatcagctc acacaccgct ggcggacacc ccagtaacaa
       61 gtgagagcgc tctgcccggc actccaccgc ctctgccccc tacccggttc cccagctctg
      121 agaagccaaa ccgacagcat cacgggcgcg gatttttctc tccaacttta tccaaccgac
      181 tacaaggaag cagcctcaac catctaacgc atggccagcc acaggattgc tttgcgtctc
      241 ctctttagcc cttctggata ttctgttcat tgatgcctca caagccccac ggagagctgt
      301 ctcccctttg cttgctccct ctgcttcctt gagttagttc tccaaggtgt taccggggtt
      361 cgggagctct tggaccgaat ggaacttttc gttgcgtctt cctgctgctg attgtgtccc
      421 tggacaagaa aaaaaggctt cgcaggcaga agaggcgcag gggaggtgga gaaagaggtg
      481 gaggaagagg acgaggagga agaggaggag gaagcctagg gggctcggcg cgggtgtgtg
      541 catgtgtgca tgcgtgtgtg agtgcatgtg tgtgagtgcc accgctgccc aggacccccg
      601 gccccgaagg tgttggctga aatatggaga atagtcttgg atgtgtttgg gtacccaagc
      661 tggcttttgt actcttcgga gcttccttgc tcagcgcaca tcttcaagtc acgggtttcc
      721 aaattaaacc tttcacgtca cttcattttg tgtctgaacc ttcggatgct gtcaccatgc
      781 ggggaggaaa tgtcctgctc aactgctctg cagagtccga ccgaggagtt ccagtcatca
      841 agtggaagaa agacggcctt atcctagcct tgggcatgga tgacagaaag cagcaacttc
      901 ctaatggatc tctgttgata caaaacatac ttcattccag acaccataag ccggatgaag
      961 gactttacca atgcgaggca tccttagcag attctggctc aattattagt cggacagcaa
     1021 aagttacggt agcagggcca ttgaggttcc tttcccagac ggaatctatc acagccttca
     1081 tgggagatac agtgttactt aagtgtgaag tcattgggga acccatgcca acaatacact
     1141 ggcagaaaaa tcaacaagac ctcaacccac tcccaggaga ctcgcgtgtg gtcgtcttgc
     1201 cctccggagc attgcagatt agccgacttc agccaggaga cagtggagtc tacagatgct
     1261 cggctcggaa tccagccagc ataagaacag gaaatgaagc agaagttaga attttatcag
     1321 acccaggcct gcataggcag ctatattttc tgcagagacc atccaacgta atagccattg
     1381 aagggaaaga tgctgtcctg gagtgctgtg tttctggcta tcctccgcca agtttcacct
     1441 ggttacgagg cgaggaggtc atccaactca ggtctaaaaa gtattcattg ttgggtggaa
     1501 gcaatttgct catctctaat gtgacagatg atgacagtgg aacctatact tgcgttgtca
     1561 cctataagaa tgagaatatt agtgcctctg cagagctcac ggtcttggtt ccgccctggt
     1621 ttttaaatca cccttccaac ctctatgcct atgagagcat ggatattgag tttgaatgtg
     1681 cagtttctgg gaagcctgtg cccactgtga attggatgaa gaatggagat gtggtgatcc
     1741 cgagtgacta ttttcagata gtgggaggaa gcaacttacg gatccttggg gtggtcaagt
     1801 cagatgaagg cttctatcaa tgtgtggctg aaaatgaggc tggcaatgcc caaagtagtg
     1861 cccagctgat tgtccccaag cctgccatcc caagctccag catcctccct tctgctccca
     1921 gagatgtgct ccctgtcttg gtttctagtc gctttgtccg tttgagctgg cgtccacctg
     1981 cagaagcaaa agggaacatt caaaccttca cagtcttttt ctccagagag ggtgacaaca
     2041 gggagcgagc tttgaataca acccagcctg ggtcccttca gcttactgtg ggaaacttga
     2101 aaccagaagc catgtacacc ttcagagttg tcgcctacaa tgagtgggga ccaggggaga
     2161 gttctcagcc catcaaggtg gccactcagc ctgagttgca agttccaggg ccagtagaaa
     2221 acctgcatgc tgtatctacc tcacctacct caattcttat tacatgggaa ccccctgcct
     2281 atgcaaatgg cccagtccaa ggttacagat tgttctgcac tgaggtgtct acaggaaaag
     2341 aacagaatat agaggttgat ggactatctt ataaactgga aggcctgaaa aaattcacgg
     2401 aatatactct tcgattccta gcttataatc gttatgggcc aggagtatct actgatgata
     2461 taacagttgt tacactttca gacgtgccaa gtgctccacc tcagaacatc tcactggaag
     2521 tggttaactc aaggagtatc aaagtaagct ggctccctcc tccatcggga acacaaaatg
     2581 gatttattac tggctataaa attcgacaca gaaagactac ccgcaggggc gagatggaaa
     2641 cactggaacc gaataacctc tggtacctct tcacaggatt ggagaaaggc agtcagtaca
     2701 gtttccaagt gtcggccatg acagtcaatg gtactggacc accttccaac tggtacacag
     2761 cggagacccc agagaatgat ttagatgagt ctcaagtccc tgaccagccg agttctcttc
     2821 acgtgaggcc ccagacaaac tgtatcatca tgagttggac acctcctctc aacccaaaca
     2881 tcgtggtgag aggctatatt attggctatg gtgttggcag tccttatgct gaaacagtgc
     2941 gtgtggacag taagcagcgg tactattcca tcgagagact agagtcgagt tctcattatg
     3001 taatctcctt aaaagctttc aacaatgccg gagaaggtgt ccctctctac gaaagtgcca
     3061 ccactcgttc cataacagat cccactgacc ccgttgatta ttatcctttg cttgatgatt
     3121 tccccacctc gggcccagat gtctccaccc ccatgctccc accagtaggt gtacaggctg
     3181 tggctcttac ccatgaggct gtgagggtca gctgggcaga caactctgtc ccgaagaacc
     3241 agaaaacatc cgatgtgcga ctgtacaccg ttcggtggag gaccagcttt tctgccagtg
     3301 ccaagtacaa gtcagaagac acaacatctc tcagttacac agcgactggc ctcaagccca
     3361 ataccatgta cgagttctca gtcatggtga ccaagaacag aaggtcaagc acgtggagca
     3421 tgactgcaca cgccaccacc tacgaagctg ccccaacttc tgctcccaag gatctgacag
     3481 tcattactcg agaggggaag cctcgtgctg tcattgtgag ctggcagcct cccttggaag
     3541 ccaatgggaa aatcactgct tatatcttgt tttatacatt ggacaagaat ataccaatag
     3601 atgattggat tatggaaact atcagcggtg accggcttac ccatcagatc atggatctca
     3661 gccttgacac gatgtattac tttcgaattc aagcacggaa tgtgaaagga gtagggcccc
     3721 tctctgatcc catcctcttc aggactttga aagtggaaca ccctgacaaa atggctaatg
     3781 accaaggtcg tcatggagat gggggttatt ggccagttga tactaacttg attgatagaa
     3841 gcactctcaa cgaaccaccc attggacaga tgcacccccc gcatggcagt gtcactcctc
     3901 agaagaacag caacctgctt gtaataaccg tggtcaccgt tggtgttctc actgtgttgg
     3961 tcgtggtgat tgtagcagtg atttgcaccc ggcgttcttc agcgcagcag aggaagaaac
     4021 gggccacaca cagtgtgagc aagaggaagg gcagtcagaa ggacctccgg cctcccgatc
     4081 tttggataca tcatgaagaa atggaaatga aaaatatcga gaagcctacg ggaaccgacc
     4141 ctgcaggaag agactccccc atccagagct gccaagatct cacaccagtc agccatagcc
     4201 agtcagaaac ccagatggga agcaaaagtg cctctcattc aggtcaggac actgaggacg
     4261 caggcagctc catgtccact ttggaacggt ccctggcagc acgccgggcc accagggcca
     4321 agctcatgat tcccatggag gcccagtcca gtaatcctgc tgttgtgagt gccatccctg
     4381 taccaacact agaaagtgcc cagtatccag gaatcctccc atctcccaca tgtggatacc
     4441 cgcatccaca gttcactctc cggccagtac cattcccaac gctgtctgtg gaccgaggtt
     4501 ttggagcagg aagaactcag tctgtgagtg aaggaccaac cacgcaacag caacccatgc
     4561 tgcccccagc tcagcccgaa catccgagca gtgaagaagc acccagtaga accatcccca
     4621 cagcctgtgt gcggccaact catccactcc gcagctttgc taacccatta ctacctccac
     4681 ccatgagtgc aatagaacca aaagtccctt acacaccgct tttgtctcag ccaggaccca
     4741 cccttcccaa gactcatgtt aaaacggcct cccttgggct ggccggaaag gcaaggtccc
     4801 ctttgcttcc cgtgtctgtg ccaacagccc ctgaagtgtc tgaggagagc cacaagccca
     4861 cagaggatcc agccagtgta tatgaacagg atgacttgag cgaacaaatg gcaagtttgg
     4921 aagggctaat gaagcaactc aacgccatca cagggtctgc cttttgacac tcattgccaa
     4981 aacgttgaga tcttctggga actttacagc ataccaatta tccataaaca gcacacctgt
     5041 gtccaaaaac tcttaccagt gtacaggtca accatctgga ccattcggtt aaggaacatc
     5101 tgaagcactt cagaagaaaa cagtatccca tcctatatgg acatcaggag tatacgatga
     5161 tggtcatgag gtcccgaaga tgcatcttca ctgcaaagtc aaggctgaag ctgctagcat
     5221 agttctgggt ctttgtcact gcagggacca tggtgtcata actaatgcct acattttcct
     5281 tcagtgagac ctttcatttt ctgtgtaggt ctagtctcac aagtgcatta tttcagcctg
     5341 taccatgcca taacaaatca atacaaactc actatttttt tcagctacag agcatccatg
     5401 gtaactctct cactccatag caccaaagga ttggatattt tcctgacagc ataaaagaaa
     5461 ataagtgaat aagcaaaagg cagtgaatgc ttgtttatag ctcaatcatt ccatctcaca
     5521 aaagtggctg atgttagtga gtgggtataa actttttacc aattttagca agtatttgta
     5581 aatccatcct tgattaacgt ttatgtctag caagtagaaa cttaaaaatc ctcaactggt
     5641 ggcatcctgc cagcaacaac acctttctag aaggagaata caatatgcaa tcttctcaga
     5701 cacgtggtga ttgtgtactt gagcttgtca taggacattt ttcgatttca gtggcttcta
     5761 tgccactcca cactgtgatg gcctgtctgg gtttcactaa ggcttcttct tcaggagttt
     5821 ggccagaaaa actccaccat cctccatccc caaccattcc cctacttctc ctgggcaagt
     5881 agccttagct aaaatggcca actccatgcg tcatatatcc tgtgtcccca atatccctct
     5941 gtggagatag tagacttcct gagagcgagc tcaagaaaga aaaggagcat gaaaaaccat
     6001 atcccagggt accttttcat gagttgatgt cccttccacc aatagcatct tcattgagcg
     6061 agctgtgcca ggcaacattg acagatgttg accacaggtt tctgttggca aggcaacctt
     6121 ccatcccatg cctaagacag tcagggagga gagagggatg ggtgccactt cacatctgca
     6181 catcataact cctgtaggta tttttccatg cagcatctaa actgtggact agaattttaa
     6241 acttctatcg ccatgtatct acggcttgaa accagctgaa tataagaaca ttctgtgcat
     6301 tcccttttag cccatgaact ttcagcggta tgtggagtta atccctattt atgcagctga
     6361 gtcgccaaga gggaactagt ttgcatattt atcagttagg tgacttgaaa acttgatgag
     6421 agtttcagct gaattattcc tttcagctct gcctttgatt tcaagcttga gtaggtcata
     6481 attttaagag agcatggcaa ggataggatc tttacaacct aatagctcct tttattaggt
     6541 gggtaattat atatgaatcc ctgaatgaaa tattttgagc aaaatggcac tgtaacagaa
     6601 ataataattc agattatttt tttacagttt tatgtcggga aggaaatctg atgtcaaaga
     6661 gagggcttgt tcaaatggtt cattagaaag tctggtccat ttgcaaaacg tttccttcaa
     6721 caagagtgct tgttcaattt actgagattt tttttttttt ctggaagtac tttcgaggaa
     6781 ctatgtgatg ttattcaatg ggacagaatg cttttgttca atatttgggc actgaggtag
     6841 acagcagttg actgacctga aataaagcat ttcttatcat agcaatgaat attttaaaaa
     6901 taatccacta cttcgaactg gaaaaatgtt tactgaacta ccataacttc ctccactccc
     6961 cagagtgtat tcccctgtct aataataaaa agaaaggaga gccacttttt agaggcattt
     7021 gatatcaatg agagtcacct caaatttcag gttggggttt gctacaaacc tcaaatttca
     7081 aattccatgg aataagttat aatgaaaggt gttctgtaac atctagttgt aaagttaaga
     7141 caaccagaat ttttataaaa ctcgaggttt ttcaaacttt caatgatttc agggagtgta
     7201 atctttaaaa gttggatgta tgctttccat ttttagtcag agttatattt cctccacaac
     7261 tcttgaaaaa ttcagtaaac aaataattta ttttagcaat tggtgactct taataagtcg
     7321 tattgtcatg ccttgaatat acattggaac catgagactg gtttcattaa ctcagtgatt
     7381 gtaacatgta tttagtccaa cacggcttct gctgagctct tgttcccatc atctttccag
     7441 tggctcacgt gtacacagta aaattcccca gggttccagg tggcaagtga attccaaggt
     7501 ctatgacggt gtgaggcagc ctgaatttgt ctagcttgtg tgtctagctc actccataca
     7561 agacccttta aacttataaa tctctttgag ccccacaggg caaagctgaa gaggcagcca
     7621 gcatctctgc caccagcagt tagttctctg gaaatgggaa aaaacatcaa acttggcagg
     7681 aggactcagg attttataca ctatgctcaa atgaaaagca agagcctgct tttaagaact
     7741 ttgctatatt ttttctattt cattttgata agaaagtaat ttccattcct ccagaaattt
     7801 ctgcatttgt ttaaactgac aaaaataaag agggctcaca atatattcaa aacatttgta
     7861 taatgcttta gtcaaaagtt aagtatttct tagtgcttat agctgcctcc atataataga
     7921 cccataatct tctagaatat ttaagtaata cagctttata tttggctctt attaaataca
     7981 tactcagttc aacaacccag aaataaaaaa ttcaaaccaa tgctataaga atccgactta
     8041 cttagggatt tctttaagga actggacata gtagtagtag tttgggtttt ttcaaaatga
     8101 agattgctaa gaatgaggca tgtgctcaga aaaggtgaca gttacaaaaa gagactccag
     8161 attaacgttt ttaagccaaa gggtgtcatt cattggcttt cccaagaaac aactccccaa
     8221 gcatgggtcc agagtttgtt ctcagagatg attgtcgaaa gttccctctc ctttggagcc
     8281 ttctcctaac ttttttactc tagtcaaaag ttaagtattt cctagtgctt acagctgcct
     8341 acatatagta gacccataat cttctagaat atttaaataa tacagcttta tattaaagtc
     8401 acctacaaat ggaacacagt gtctcagaca tgatagatgc acagtgagtc ccacgaacag
     8461 ttacttacgt cctaagaggc atcctgccat ttttcataaa accttaacct gggttctgga
     8521 agtgttggaa tgcttatttc cagtcagcaa gacataggaa atggaaaact cccaagtctt
     8581 gcgtgaatct aaagaaataa tagtaatgtg gacttcaaaa agatgcagag caagtgtata
     8641 gaatctgtat attctacctt tcttatcaag ttctctttat gcaaccacag gatgtcccca
     8701 aaggccaaaa tttagtatca gggcttcata tacctgggta gatctcttta ctgaaatgta
     8761 agtgaaataa gtacctaata aaaattcaaa ataaaaacaa aaagaagaag aagaagaaga
     8821 agaagaagaa gaagaagaag aagaagaaga agaagaagaa gaagaagaag aagaagaaag
     8881 ggccaagcta ccacactttc cttttctaaa ctcaaattga aagcaacatt ctcatcattc
     8941 gtattcatct aatgattttc agaaatcatt taaatactac tcagacaagc tttgtacttt
     9001 aacatttttt aaagtcattc gggtagttga gaaaaatcac agataggtgt tttttgtgat
     9061 acccccaatg aacagaacat atatgtcccc aggccccagt ctaccttgtg ggtcaaataa
     9121 aactgcttcc aaaaatattt gatttgtaac agaaatgcta tatttcttgt cagtgaggtt
     9181 agataggaga caatgccaca cccatatcaa caaatgacat gacttctgat ctggcccacc
     9241 ccttctgcca ttggataact cttcactggg aagacttcca gcaacacagc agcactctga
     9301 agggcgtttt tctcttgctc tcagttttgt gctttaccac cttatgatct tttatttttt
     9361 tttttatttt ttggttggta ggagagcaac agcaaaaact gtgcaaggaa tagcaaacac
     9421 aagaggcatg ggccaaggga tctcactgtg tgttcgatgt gtattttcag atgcaagaaa
     9481 ggaatgttgg cgaagaggaa acgtgtgttt ttttattatt gtagggtaaa cctgacgatt
     9541 ctgaactttg cgaattgtca gcttgtttgg gggaagggcg ggtgggtatg aggggtactt
     9601 tttataagta atatttaatt tattatttag aagtggcttc tttttggata atttatgata
     9661 caaagggaga tacagttggg atctaggcat ggctgttaaa gctgaagtgt tttgtatctc
     9721 agaaggaccg ttttagaaac ggactgtcca atgctgagcc tgagggaatg aacatccagg
     9781 ccaagcaaag ccttcactaa aaattccacc atctccacct tctccctatc gagggtttca
     9841 aagatgataa caccaaacct aaagtaactc ggatagcatt ttccaaacca gtgctattca
     9901 ttctttccaa gggctttgca actcaaacta ttagtgtgat agtgatgtgt ttatttggta
     9961 gaaatgggta tactacagct ttaatagcct tagtggaaag agaaactttt tgttgttaca
    10021 aaacactttt tttttcatag aaaggtgttt tgagcctaca aagagtctct tggaattgtc
    10081 agactctagc attgttaacc aaattagagt agtgattgca atatttaagt gtaaatgttg
    10141 ttctatgaga aaggaagctt gcttacagtt taaaacacga tgactgtttc tacacacgaa
    10201 cttgtatacc actacacaag gaaaaggggg ttttgtaatc actgtagaac agtctcctat
    10261 tcatttttta tagaaatgtt attccaatgg tgcatttttt tgtttaataa ataaagtttt
    10321 gatac
//
