LOCUS       NM_001357204            3913 bp    mRNA    linear   ROD 24-DEC-2022
DEFINITION  Mus musculus DDB1 and CUL4 associated factor 8 (Dcaf8), transcript
            variant 2, mRNA.
ACCESSION   NM_001357204 XM_006497065
VERSION     NM_001357204.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3913)
  AUTHORS   Brandao R, Kwa MQ, Yarden Y and Brakebusch C.
  TITLE     ACK1 is dispensable for development, skin tumor formation, and
            breast cancer cell proliferation
  JOURNAL   FEBS Open Bio 11 (6), 1579-1592 (2021)
   PUBMED   33730447
REFERENCE   2  (bases 1 to 3913)
  AUTHORS   Zhang X, Xia Z, Lv X, Li D, Liu M, Zhang R, Ji T, Liu P and Ren R.
  TITLE     DDB1- and CUL4-associated factor 8 plays a critical role in
            spermatogenesis
  JOURNAL   Front Med 15 (2), 302-312 (2021)
   PUBMED   33855678
  REMARK    GeneRIF: DDB1- and CUL4-associated factor 8 plays a critical role
            in spermatogenesis.
REFERENCE   3  (bases 1 to 3913)
  AUTHORS   Nowak M, Suenkel B, Porras P, Migotti R, Schmidt F, Kny M, Zhu X,
            Wanker EE, Dittmar G, Fielitz J and Sommer T.
  TITLE     DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy
  JOURNAL   J Cell Sci 132 (17) (2019)
   PUBMED   31391242
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3913)
  AUTHORS   Zhang YL, Zhao LW, Zhang J, Le R, Ji SY, Chen C, Gao Y, Li D, Gao S
            and Fan HY.
  TITLE     DCAF13 promotes pluripotency by negatively regulating SUV39H1
            stability during early embryonic development
  JOURNAL   EMBO J 37 (18) (2018)
   PUBMED   30111536
REFERENCE   5  (bases 1 to 3913)
  AUTHORS   Li G, Ji T, Chen J, Fu Y, Hou L, Feng Y, Zhang T, Song T, Zhao J,
            Endo Y, Lin H, Cai X and Cang Y.
  TITLE     CRL4DCAF8 Ubiquitin Ligase Targets Histone H3K79 and Promotes H3K9
            Methylation in the Liver
  JOURNAL   Cell Rep 18 (6), 1499-1511 (2017)
   PUBMED   28178526
REFERENCE   6  (bases 1 to 3913)
  AUTHORS   Eddleston J, Murdoch JN, Copp AJ and Stanier P.
  TITLE     Physical and transcriptional map of a 3-Mb region of mouse
            chromosome 1 containing the gene for the neural tube defect mutant
            loop-tail (Lp)
  JOURNAL   Genomics 56 (2), 149-159 (1999)
   PUBMED   10051400
REFERENCE   7  (bases 1 to 3913)
  AUTHORS   Underhill DA, Mullick A, Groulx N, Beatty BG and Gros P.
  TITLE     Physical delineation of a 700-kb region overlapping the Looptail
            mutation on mouse chromosome 1
  JOURNAL   Genomics 55 (2), 185-193 (1999)
   PUBMED   9933565
REFERENCE   8  (bases 1 to 3913)
  AUTHORS   Welch CL, Xia YR, Hong H, Stallcup MR and Lusis AJ.
  TITLE     Localization of the mouse glucocorticoid receptor-interacting
            protein 1 gene (Grip1) to proximal chromosome 1 by linkage analysis
  JOURNAL   Mamm Genome 8 (8), 620-621 (1997)
   PUBMED   9250876
REFERENCE   9  (bases 1 to 3913)
  AUTHORS   Welch CL, Xia YR, Shechter I, Farese R, Mehrabian M, Mehdizadeh S,
            Warden CH and Lusis AJ.
  TITLE     Genetic regulation of cholesterol homeostasis: chromosomal
            organization of candidate genes
  JOURNAL   J Lipid Res 37 (7), 1406-1421 (1996)
   PUBMED   8827514
  REMARK    Erratum:[J Lipid Res 1996 Oct;37(10):2269]
REFERENCE   10 (bases 1 to 3913)
  AUTHORS   Warden CH, Mehrabian M, He KY, Yoon MY, Diep A, Xia YR, Wen PZ,
            Svenson KL, Sparkes RS and Lusis AJ.
  TITLE     Linkage mapping of 40 randomly isolated liver cDNA clones in the
            mouse
  JOURNAL   Genomics 18 (2), 295-307 (1993)
   PUBMED   8288233
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC074310.29.
            
            [WARNING] On May 13, 2023 this sequence was replaced by
            NM_001357204.2.
            
            On Oct 24, 2017 this sequence version replaced XM_006497065.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660821.195019.1, BC023804.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-324               AC074310.29        79063-79386         c
            325-397             AC074310.29        78080-78152         c
            398-468             AC074310.29        61483-61553         c
            469-1121            AC074310.29        54420-55072         c
            1122-1262           AC074310.29        53318-53458         c
            1263-1357           AC074310.29        51824-51918         c
            1358-1468           AC074310.29        47384-47494         c
            1469-1541           AC074310.29        41033-41105         c
            1542-1599           AC074310.29        40489-40546         c
            1600-1707           AC074310.29        39941-40048         c
            1708-1838           AC074310.29        38332-38462         c
            1839-1958           AC074310.29        34764-34883         c
            1959-2075           AC074310.29        33500-33616         c
            2076-3913           AC074310.29        31008-32845         c
FEATURES             Location/Qualifiers
     source          1..3913
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 79.54 cM"
     gene            1..3913
                     /gene="Dcaf8"
                     /gene_synonym="D1Dau35e; D1Ucla4; H326; Wdr42a"
                     /note="DDB1 and CUL4 associated factor 8"
                     /db_xref="GeneID:98193"
                     /db_xref="MGI:MGI:91860"
     exon            1..324
                     /gene="Dcaf8"
                     /gene_synonym="D1Dau35e; D1Ucla4; H326; Wdr42a"
                     /inference="alignment:Splign:2.1.0"
     exon            325..397
                     /gene="Dcaf8"
                     /gene_synonym="D1Dau35e; D1Ucla4; H326; Wdr42a"
                     /inference="alignment:Splign:2.1.0"
     exon            398..468
                     /gene="Dcaf8"
                     /gene_synonym="D1Dau35e; D1Ucla4; H326; Wdr42a"
                     /inference="alignment:Splign:2.1.0"
     CDS             417..2192
                     /gene="Dcaf8"
                     /gene_synonym="D1Dau35e; D1Ucla4; H326; Wdr42a"
                     /note="WD repeat domain 42A; WD repeat-containing protein
                     42A"
                     /codon_start=1
                     /product="DDB1- and CUL4-associated factor 8"
                     /protein_id="NP_001344133.1"
                     /db_xref="CCDS:CCDS15509.1"
                     /db_xref="GeneID:98193"
                     /db_xref="MGI:MGI:91860"
                     /translation="MSNKRPNTTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEA
                     SDLSLSLTGDDGGPNRTSTESRGTDTESSGEEKDSDSMEDTGHYSINDESRGHGHSDE
                     EDEEQPRHRGQRKRASRDQDSSDDERALEDWVSSETTALPRPRWQALPALRERELGSS
                     ARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVR
                     RQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQH
                     KGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVN
                     PANTHQFAVGGRDQYVRIYDQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHD
                     GTELLASYNDEDIYLFNSSHSDGAQYIKRYKGHRNNATVKGVNFYGPKSEFVVSGSDC
                     GHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTE
                     LTGLKEVIKKNKRERDEDSLHHTDLFDSHMLWFLMHHLRQRRHHRRWREPGVGATDAD
                     SDESPSSSDTSDEEEGPDRVQCMPS"
     exon            469..1121
                     /gene="Dcaf8"
                     /gene_synonym="D1Dau35e; D1Ucla4; H326; Wdr42a"
                     /inference="alignment:Splign:2.1.0"
     exon            1122..1262
                     /gene="Dcaf8"
                     /gene_synonym="D1Dau35e; D1Ucla4; H326; Wdr42a"
                     /inference="alignment:Splign:2.1.0"
     exon            1263..1357
                     /gene="Dcaf8"
                     /gene_synonym="D1Dau35e; D1Ucla4; H326; Wdr42a"
                     /inference="alignment:Splign:2.1.0"
     exon            1358..1468
                     /gene="Dcaf8"
                     /gene_synonym="D1Dau35e; D1Ucla4; H326; Wdr42a"
                     /inference="alignment:Splign:2.1.0"
     exon            1469..1541
                     /gene="Dcaf8"
                     /gene_synonym="D1Dau35e; D1Ucla4; H326; Wdr42a"
                     /inference="alignment:Splign:2.1.0"
     exon            1542..1599
                     /gene="Dcaf8"
                     /gene_synonym="D1Dau35e; D1Ucla4; H326; Wdr42a"
                     /inference="alignment:Splign:2.1.0"
     exon            1600..1707
                     /gene="Dcaf8"
                     /gene_synonym="D1Dau35e; D1Ucla4; H326; Wdr42a"
                     /inference="alignment:Splign:2.1.0"
     exon            1708..1838
                     /gene="Dcaf8"
                     /gene_synonym="D1Dau35e; D1Ucla4; H326; Wdr42a"
                     /inference="alignment:Splign:2.1.0"
     exon            1839..1958
                     /gene="Dcaf8"
                     /gene_synonym="D1Dau35e; D1Ucla4; H326; Wdr42a"
                     /inference="alignment:Splign:2.1.0"
     exon            1959..2075
                     /gene="Dcaf8"
                     /gene_synonym="D1Dau35e; D1Ucla4; H326; Wdr42a"
                     /inference="alignment:Splign:2.1.0"
     exon            2076..3913
                     /gene="Dcaf8"
                     /gene_synonym="D1Dau35e; D1Ucla4; H326; Wdr42a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgcggccac cgggagggtt gggagcccag agctcgcggg accgctctcg ctcagtctcc
       61 tccagcacag cgtcgcaaac cccgccggaa agcgtgacgg cgcaggcgca ggcgcggaga
      121 cccgagacgg tggtggtggc tgccgctggc cagtgtaaga tggcggcggc gttggtggcg
      181 gcagtggacg gggcggctgg gcctggaaca gtcggagcat ccgctggcag aaggatgacc
      241 ctagatggga agcgggctgc cgggcctcgc cagctcccgt gcttgtaact gccccagccg
      301 gacgccctcc ccttgaccta ccggttcttc agcgaacctc cagaccagtt ttctcaggat
      361 cttgggcctg acttcggtcg gcgataaaag caggaaggct ggcgaccata tttaagatgt
      421 ccaataaacg tcccaacacg acagatggga gaacagattt agctaatgga agtctgtcca
      481 gcagcccaga ggagatgtct ggagctgaag aggggaggga aacatcctca gggattgaag
      541 tagaggcatc agacctgagt ctcagcttga ctggggatga cggtggcccc aaccgcacca
      601 gcacggaaag tcgtggcaca gacacagaga gctcagggga agaaaaggac tctgacagca
      661 tggaggacac gggccattat tccatcaatg atgaaagccg aggtcatggc cactcagacg
      721 aagaggacga ggaacaacct cggcaccgtg gacagcgcaa acgggccagc cgtgaccagg
      781 attcatcaga tgatgagcga gccctggaag actgggtatc ttcagagaca acagccttac
      841 cccgacctcg ctggcaagcc cttcctgcgc ttcgggagcg ggaactgggt tccagtgccc
      901 gctttgtgta cgaggcttgt ggagctagag tctttgtaca gcgtttccgt ttgcagcacg
      961 ggcttgaggg ccatactggt tgtgtcaata ccttgcactt taaccagcgt ggtacctggc
     1021 tggccagtgg cagtgatgac ctgaaggtgg tggtgtggga ttgggtgcgg cggcagccag
     1081 tactggactt tgagagtggc cacaaaagta atgtcttcca ggccaagttc cttcctaaca
     1141 gtggtgactc caccctggct atgtgtgccc gggatggaca ggtccgagtc gcagagctgt
     1201 ctgctacaca gtgctgcaag aacaccaagc gtgtggccca gcacaagggg gcatctcaca
     1261 agttagccct agaaccagac tccccctgca cgttcctgtc agctggtgaa gatgccgtcg
     1321 tcttcaccat tgacctgaga caagaccggc cagcttcgaa actagtggtg acaaaagaga
     1381 aggagaagaa agtggggctg tatacaatct atgtgaaccc tgccaatacc caccagtttg
     1441 cagtgggtgg aagagatcag tatgtaagga tttatgacca gaggaaaatt gatgagaatg
     1501 agaacaacgg agtcctgaaa aaattctgtc ctcaccactt ggtgaacagt gagtccaaag
     1561 caaacatcac ctgtcttgtg tacagccacg acggcacaga gctcctggcc agttacaatg
     1621 atgaagacat ttaccttttc aactcttctc acagtgatgg ggcccagtat attaagagat
     1681 acaaaggcca tagaaataat gctacagtaa aaggcgtcaa tttctatggc cccaagagtg
     1741 agtttgtggt gagcggtagt gactgcgggc acatcttcct ctgggagaag tcatcttgcc
     1801 agattattca gttcatggaa ggggacaagg gaggtgtggt aaactgtctt gagccccatc
     1861 ctcatctgcc tgttttggca accagtggcc tagaccatga tgtgaagatc tgggcgccga
     1921 cagctgaagc ttccactgag ctgacagggt taaaggaagt gatcaagaag aacaagcgag
     1981 agcgggatga agacagcttg caccacactg atctgtttga tagtcacatg ctgtggttcc
     2041 ttatgcatca cctgagacag agacgccatc atcggcgctg gcgagaacct ggggttgggg
     2101 ccacagatgc agactctgat gagtctccca gctcctcaga cacatccgac gaggaggagg
     2161 gccctgaccg ggtgcagtgc atgccatcct gaggccccac acctaggagg gatgggctgg
     2221 ggctgccaac ccgatcctgc ctgggcaact ctttttcagt cccaggccct tacattcaac
     2281 agaaatgcac tttggacttt ttgtttaaat aaaagaaaga tacctgagga ggacagagca
     2341 caggagacgg aaccagcaga gagcccctag aagtgagaga tgagaaggag cctgaatgag
     2401 cttccatgga aggtgcaaag gactcagaga aatgggcctc tccctgaagc cttttgtcaa
     2461 tgggcttgga taggaagtgg ggcttctttt tctttaacct cccttgtttc ttttgggggt
     2521 ggggggtacc aataggccag agagaaggct gggcatgcca ctctctttgg tttagggttt
     2581 cacctttttt ttttcctttg ttttttaaga agtctgacag ttgctttgtt ttttgcccga
     2641 gcaaccacgt cccatcccag gatcctgttt ttctgggaaa tccttaagag cccccagcca
     2701 ccccagcact ctgctctccc ttccacaaca cttactctct gaccttacca cagtgctctg
     2761 cactgctgcc cgttgtctcc ttcactcact cgtcatccag cgccctctaa atgggggctg
     2821 ggatggggac tgaggagacg tgggagggac aagagacgga aaaacaggaa gaagttacct
     2881 cttggttttg gttttaactg ttcagtggtg gcaatttccc tgtccctatc actgttagag
     2941 gcctactttt atatctataa atatattaaa aagcaagtta aacttggatg tatcaagtta
     3001 aaattattgt cagaagttta aatacctata tattctctat gaatccaatg caataaaggg
     3061 gctgcaagga agagcaagcg atcgagtgat gctgaagagg tgacgtgggt cagatgattc
     3121 atggctgctc tcagagccta gggcttacct gtagctttcc caaggctcaa gggtggaaac
     3181 atagtcagct gtgcccttct ctgcctcagt actgagcttt agaaaaacaa attcctctca
     3241 actttgcctc aggtctccta atttctgtaa gtctgtgggg gctcccaaga ttgctcctct
     3301 cattagaggc tggcctgtct ctaaaacatg actgaagtgt gacttcagga agggcgtcac
     3361 tgctgcagac tgtctcctgg ttctgagtat aacggaaagc acactcgccc cctcccttta
     3421 gttagctgct tgattcttta agcatccaac tccacaccag ctcccttcct aatggaagga
     3481 tgaagggaga gcttcctggg aatcaaggga caagccagta attggaggat ttattctggt
     3541 gcctggggct tagagccctg tcttcagcac tggccactga gtatgaaagt ccctgtggaa
     3601 ttcttaccct aaatgcttgt gctgctcttc ctgtgccccg gtgttcacaa ggtccagtca
     3661 ggaggcctac accatgggat ggaagttgga gagagagcgg agggtggtat cctacacact
     3721 ctttcctctt gaccccatcc agcagcgcag gccagatgcc agctcctggg cttccttcgt
     3781 ggcagggagt gtgtggtaac tgagtagtag tcttatgtcc tcactgctag agggatgatg
     3841 aggtgggctt aaaaccatgc actctggaat ttgttgtatt tttttctcag taaagctttt
     3901 cccctgactg ctg
//
