LOCUS       NM_001357322            2236 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus DDB1 and CUL4 associated factor 15 (Dcaf15),
            transcript variant 2, mRNA.
ACCESSION   NM_001357322 XM_006530808
VERSION     NM_001357322.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2236)
  AUTHORS   Zhang,Y.L., Zhao,L.W., Zhang,J., Le,R., Ji,S.Y., Chen,C., Gao,Y.,
            Li,D., Gao,S. and Fan,H.Y.
  TITLE     DCAF13 promotes pluripotency by negatively regulating SUV39H1
            stability during early embryonic development
  JOURNAL   EMBO J 37 (18) (2018)
   PUBMED   30111536
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC159266.3, BY273847.1, AK032982.1 and BB803815.1.
            
            On Oct 25, 2017 this sequence version replaced XM_006530808.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC057552.1, AK144808.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 AC159266.3         97044-97046         c
            4-24                BY273847.1         4-24
            25-655              AK032982.1         2-632
            656-656             AC159266.3         94187-94187         c
            657-2230            AK032982.1         634-2207
            2231-2236           BB803815.1         388-393
FEATURES             Location/Qualifiers
     source          1..2236
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 40.3 cM"
     gene            1..2236
                     /gene="Dcaf15"
                     /gene_synonym="6720484B16"
                     /note="DDB1 and CUL4 associated factor 15"
                     /db_xref="GeneID:212123"
                     /db_xref="MGI:MGI:2684420"
     exon            1..181
                     /gene="Dcaf15"
                     /gene_synonym="6720484B16"
                     /inference="alignment:Splign:2.1.0"
     CDS             50..1852
                     /gene="Dcaf15"
                     /gene_synonym="6720484B16"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /codon_start=1
                     /product="DDB1- and CUL4-associated factor 15 isoform 2"
                     /protein_id="NP_001344251.1"
                     /db_xref="CCDS:CCDS90424.1"
                     /db_xref="GeneID:212123"
                     /db_xref="MGI:MGI:2684420"
                     /translation="MAPSSKSERNSGAGSAGGGPGGTGGKRAVGRRREHVLKQLERVK
                     ISGQLSPRLFRKLPPRVCVSLKNIVDEDFLYAGHIFLGFSKCGRYVLSYTSSSGDDDF
                     SFYIYHLYWWEFNVHSKLKLVRQVRLFQDEEIYSDLYLTVCEWPSDASKVIVFGFNTR
                     SANGMLMNMMMMSDENHRDIYISTVAVPPRGRCAACQDASRAHPGDPSAQCLRHGFML
                     HTKYQVVYPFPTFQPAFQLKKDQVVLLNTSYSLVACAVSVHSAGDSSFCQILYDHTAL
                     PPAPPSSPGPWSPEAAPAFPSLGVEVVPAQPSGAPEPSPAIAKAKEFVADIFRRAKEA
                     KGSPLEETRLPSSLGPSSSRCRPSLEPQAPSGEVVPRDSPPAAETTAPEPGYINYTKL
                     HYVLQSGEGTEPEDEFEDDKISLPFVVTDLRGRNLRPMRERTDMQGQYLTVEQLTLDF
                     EYVINEVIRHDATWGHQFCSFSDYDIVILEVCPETNQVLINIGLLLLAFPAPTEEGQL
                     RPKTYHTSLKVAWDLNTGIFETVSVGDLTEVKGQTSGSVWSSYRKSCVDMVMKWLVPE
                     SSGRYVNRMTNEALHKGCSLKVLADSERYTWIVL"
     exon            182..279
                     /gene="Dcaf15"
                     /gene_synonym="6720484B16"
                     /inference="alignment:Splign:2.1.0"
     exon            280..415
                     /gene="Dcaf15"
                     /gene_synonym="6720484B16"
                     /inference="alignment:Splign:2.1.0"
     exon            416..522
                     /gene="Dcaf15"
                     /gene_synonym="6720484B16"
                     /inference="alignment:Splign:2.1.0"
     exon            523..662
                     /gene="Dcaf15"
                     /gene_synonym="6720484B16"
                     /inference="alignment:Splign:2.1.0"
     exon            663..833
                     /gene="Dcaf15"
                     /gene_synonym="6720484B16"
                     /inference="alignment:Splign:2.1.0"
     exon            834..1268
                     /gene="Dcaf15"
                     /gene_synonym="6720484B16"
                     /inference="alignment:Splign:2.1.0"
     exon            1269..1360
                     /gene="Dcaf15"
                     /gene_synonym="6720484B16"
                     /inference="alignment:Splign:2.1.0"
     exon            1361..1489
                     /gene="Dcaf15"
                     /gene_synonym="6720484B16"
                     /inference="alignment:Splign:2.1.0"
     exon            1490..1575
                     /gene="Dcaf15"
                     /gene_synonym="6720484B16"
                     /inference="alignment:Splign:2.1.0"
     exon            1576..1680
                     /gene="Dcaf15"
                     /gene_synonym="6720484B16"
                     /inference="alignment:Splign:2.1.0"
     exon            1681..1796
                     /gene="Dcaf15"
                     /gene_synonym="6720484B16"
                     /inference="alignment:Splign:2.1.0"
     exon            1797..2236
                     /gene="Dcaf15"
                     /gene_synonym="6720484B16"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2212..2217
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dcaf15"
                     /gene_synonym="6720484B16"
                     /note="hexamer: ACTAAA"
     polyA_site      2231
                     /gene="Dcaf15"
                     /gene_synonym="6720484B16"
                     /note="major polyA site"
ORIGIN      
        1 ggcggggcta agggaccggt tgctccggaa gtggagggag ggggtgaaaa tggcgcccag
       61 ctcgaaatcg gagcggaaca gcggggccgg gagcgccggc ggaggccctg gggggaccgg
      121 ggggaagcgg gcggtggggc ggcggcggga acacgttctc aagcagctgg agcgagtcaa
      181 gatcagtggg cagctctcac ctcgtctttt ccggaagctg ccccccaggg tctgcgtgtc
      241 cctcaagaac atcgtagatg aggattttct ctatgcaggc catatcttcc tgggattttc
      301 caagtgtggc cgctatgtcc tctcctacac cagcagcagt ggggatgacg acttctcctt
      361 ctacatatat cacctctact ggtgggagtt caacgtccac agcaagctca agctggtccg
      421 gcaggtgcgg ctcttccagg acgaggagat ctacagtgac ctgtacctga ctgtgtgtga
      481 gtggcctagc gacgcttcca aggtcatcgt gtttggtttc aacacccgct cggccaacgg
      541 gatgctcatg aacatgatga tgatgagcga tgagaaccat cgtgacatct acatcagcac
      601 tgtggctgtg ccacctcggg gccgttgtgc tgcctgccag gatgccagtc gtgcccaccc
      661 aggggaccca agcgcacagt gcctgcggca tggcttcatg ctgcacacca aataccaggt
      721 ggtgtacccc ttccccacct tccaacccgc cttccaactc aagaaggatc aggtggtgct
      781 gctcaacacc agctactccc tggtggcctg cgctgtctct gtccactcag caggtgacag
      841 cagtttctgc caaatcctgt atgaccacac agctttgccc ccagccccac ccagttctcc
      901 aggaccttgg agccctgagg cagccccagc cttccccagt cttggtgttg aggtggtccc
      961 agcccagccc tctggagccc ctgagccctc accagccatt gccaaggcca aggagtttgt
     1021 agctgacatc ttccgcaggg ctaaagaggc caagggtagt cccttggagg aaactcggct
     1081 gccctctagc ttggggccct caagcagccg ctgccgccca tctttagagc cgcaagcccc
     1141 aagtggggaa gtggtaccca gggacagccc tcctgctgca gagaccactg cccctgagcc
     1201 tggctacatc aattacacca agttgcacta tgtgttgcag tctggggaag ggacagagcc
     1261 tgaggatgag tttgaggatg acaagatctc cctgcctttt gtggtgactg atctccgtgg
     1321 ccgcaactta cggcccatgc gagagcggac agacatgcag ggccagtacc tgacagtgga
     1381 gcagcttacc ctggacttcg agtatgtcat caatgaggtc atccgccatg atgccacttg
     1441 gggtcaccag ttctgctctt tcagtgacta tgacatagtc atcttggagg tctgcccaga
     1501 aaccaaccag gtcctgatca acattggcct gctgctcttg gcctttccag ctcccactga
     1561 agagggccag cttcgaccca agacctatca caccagtctc aaggtggcct gggacctcaa
     1621 cacaggcatc tttgagacag tcagcgtggg tgatctaact gaggtcaaag gacagaccag
     1681 tggcagtgtc tggagctcct accgaaagag ctgtgtggac atggtcatga aatggctggt
     1741 gccagagagc agtggccgct atgtgaacag gatgacaaac gaggcactgc acaaagggtg
     1801 ctcactgaag gttctggcag acagtgagcg gtacacttgg attgtgctgt gagggctgga
     1861 ctgccctgga ccctgactcc aactacctcc acgggcccgg agaggaccgc cttcctgggc
     1921 tggccctaca agggccacaa ccggcactag tgttaggttg caggatggat gggactggca
     1981 cagcagcctc tggtggcccg agagtctgga tgtgtcttta tttatgccta tttaagttgg
     2041 gaaaggcaga gagaggagcc ctggcctgcc ccagcgaagc ccagtcctgc ttcctgcgct
     2101 ctggcccttg tccttggctg caagtgtagc cctctagggc tgccagtggt tccagcctcc
     2161 ctcacttggg gggtgggggg agccccgtgg tggcctcgcc ttgttccatg tactaaatgc
     2221 tttatttctg acctgc
//
