LOCUS       NM_178739               3512 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus DDB1 and CUL4 associated factor 12-like 1 (Dcaf12l1),
            transcript variant A, mRNA.
ACCESSION   NM_178739
VERSION     NM_178739.6
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3512)
  AUTHORS   Houston,B.J., Lopes,A.M., Laan,M., Nagirnaja,L., O'Connor,A.E.,
            Merriner,D.J., Nguyen,J., Punab,M., Riera-Escamilla,A., Krausz,C.,
            Aston,K.I., Conrad,D.F. and O'Bryan,M.K.
  TITLE     DDB1- and CUL4-associated factor 12-like protein 1 (Dcaf12l1) is
            not essential for male fertility in mice
  JOURNAL   Dev Biol 490, 66-72 (2022)
   PUBMED   35850260
  REMARK    GeneRIF: DDB1- and CUL4-associated factor 12-like protein 1
            (Dcaf12l1) is not essential for male fertility in mice.
REFERENCE   2  (bases 1 to 3512)
  AUTHORS   Sasaki,K., Hara,S., Yamakami,R., Sato,Y., Hasegawa,S., Kono,T.,
            Morohaku,K. and Obata,Y.
  TITLE     Ectopic expression of DNA methyltransferases DNMT3A2 and DNMT3L
            leads to aberrant hypermethylation and postnatal lethality in mice
  JOURNAL   Mol Reprod Dev 86 (6), 614-623 (2019)
   PUBMED   30834655
REFERENCE   3  (bases 1 to 3512)
  AUTHORS   Pearton,D.J., Smith,C.S., Redgate,E., van Leeuwen,J., Donnison,M.
            and Pfeffer,P.L.
  TITLE     Elf5 counteracts precocious trophoblast differentiation by
            maintaining Sox2 and 3 and inhibiting Hand1 expression
  JOURNAL   Dev Biol 392 (2), 344-357 (2014)
   PUBMED   24859262
REFERENCE   4  (bases 1 to 3512)
  AUTHORS   Shalom-Barak,T., Zhang,X., Chu,T., Timothy Schaiff,W., Reddy,J.K.,
            Xu,J., Sadovsky,Y. and Barak,Y.
  TITLE     Placental PPARgamma regulates spatiotemporally diverse genes and a
            unique metabolic network
  JOURNAL   Dev Biol 372 (1), 143-155 (2012)
   PUBMED   22967998
REFERENCE   5  (bases 1 to 3512)
  AUTHORS   Gallardo,T.D., John,G.B., Shirley,L., Contreras,C.M., Akbay,E.A.,
            Haynie,J.M., Ward,S.E., Shidler,M.J. and Castrillon,D.H.
  TITLE     Genomewide discovery and classification of candidate ovarian
            fertility genes in the mouse
  JOURNAL   Genetics 177 (1), 179-194 (2007)
   PUBMED   17660561
  REMARK    GeneRIF: Transcripts highly enriched in ovary; gene identified as
            candidate female fertility factor.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK034472.1, AK038557.1, AL670238.5 and BB337276.1.
            
            On Jul 7, 2010 this sequence version replaced NM_178739.5.
            
            Transcript Variant: This variant (A) represents the longer
            transcript. Both variants A and B encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK034472.1, BC068319.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-46                AK034472.1         1-46
            47-500              AK038557.1         2-455
            501-501             AL670238.5         134803-134803       c
            502-3507            AK038557.1         457-3462
            3508-3512           BB337276.1         284-288
FEATURES             Location/Qualifiers
     source          1..3512
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 24.0 cM"
     gene            1..3512
                     /gene="Dcaf12l1"
                     /gene_synonym="9330180J20; A230038L21Rik; Decaf12l1;
                     Wdr40b"
                     /note="DDB1 and CUL4 associated factor 12-like 1"
                     /db_xref="GeneID:245404"
                     /db_xref="MGI:MGI:2444462"
     exon            1..1785
                     /gene="Dcaf12l1"
                     /gene_synonym="9330180J20; A230038L21Rik; Decaf12l1;
                     Wdr40b"
                     /inference="alignment:Splign:2.1.0"
     CDS             279..1784
                     /gene="Dcaf12l1"
                     /gene_synonym="9330180J20; A230038L21Rik; Decaf12l1;
                     Wdr40b"
                     /note="WD repeat domain 40B; WD repeat-containing protein
                     40B"
                     /codon_start=1
                     /product="DDB1- and CUL4-associated factor 12-like protein
                     1"
                     /protein_id="NP_848854.3"
                     /db_xref="CCDS:CCDS30101.1"
                     /db_xref="GeneID:245404"
                     /db_xref="MGI:MGI:2444462"
                     /translation="MRQADSQTQPSPAEQETPQPAGPSNRSPPTMGPQQTGSRKRKAA
                     EVDQGAGTSSSPGPAAPMATAGEGNAEGSMLLTKRPRRPVAHLSMVNYLKGRALGADG
                     HPGLAGFEGDLRSYGVLRLPELLRERQLTLGPLNKVFASQWLNARQVVCGTKCNTLFV
                     VDVKTDHIMRIPLMRDRVPDLSRGPPSCGIHAVELNPSKTLLATGGENPNSLAVYQLP
                     TLDPVCLGDCQGHRDWIFAIAWMSDTVAVSGSRDGTVALWKVDPDMFNGSIAWHKDAG
                     LPVYAHISPTDMEAIPKATTNPGNRKVRALAFSNKNQELGAVSLDGYFHLWKARSSLS
                     RLLSLRLPYCRENVCLTYCDEFSLYAVGSQSHVSFLDLRQGQQNIPPLCSREGGTGVR
                     SLSVHQHIVTVGTGHGSLLFYDIRAQKFLEERSAANPDMFPVPSGRKLKLTCGSGWIN
                     QDDLLENYVAGVEDFPNALYTHCYNWPEMKLFVGGGPLASGLHGNYAGLWS"
     exon            1786..3512
                     /gene="Dcaf12l1"
                     /gene_synonym="9330180J20; A230038L21Rik; Decaf12l1;
                     Wdr40b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtctttatc tccaacggac tcgtcgctca aggcccagaa gtccacactc ctgagctggt
       61 tggcagcaga gtctccactc tctctctagc cgcaccttcg gcctcagcgc cgatcctccc
      121 gagctcgctc ggctctttcc gcccgacctc gcgttgttcg ccgggtcacg ccgccaccac
      181 ctcctttgcc gccaaggctc tccggactcg gtaggctccc cgctgatcgg ttgatcgctc
      241 tctcactagc tccttagcct ccagctcccg gtgatatcat gcgtcaggcc gactcccaga
      301 cgcagccctc tcccgcagag caggagacgc cgcagcctgc agggccctcc aaccgctcgc
      361 cgcccaccat gggcccgcag caaacaggta gcaggaagcg gaaagccgcc gaggtcgatc
      421 agggcgccgg gacttcttca tcgccaggcc ccgcagcgcc gatggcgaca gctggggagg
      481 gcaacgcaga ggggtccatg ctgctgacca agaggccgcg gcggcccgta gctcacctct
      541 ccatggtgaa ctacctgaag ggccgagcgc tgggcgcaga tggccacccg gggctcgctg
      601 gcttcgaggg agatctgcgc agttacgggg tcctcaggct acccgagctg ctgagggagc
      661 gccagctgac cctaggcccc ctcaataagg tgttcgcatc gcagtggctc aatgccaggc
      721 aggtggtgtg tggcactaag tgcaacacac tcttcgtggt tgatgtcaag accgaccaca
      781 tcatgcgcat tcctctgatg cgcgacaggg tacccgacct gtctcgtggc ccgccctcct
      841 gtggcattca tgctgtggag ctgaatccct ccaagaccct cttggcaact ggaggtgaaa
      901 accccaatag cctggcagtc taccagttgc ccactctgga tccggtgtgc ctaggagatt
      961 gccaaggcca cagggactgg atctttgcca ttgcatggat gagtgacacc gtggctgtga
     1021 gtggctcccg cgacggcacc gtggcacttt ggaaggtgga tcctgacatg ttcaatggca
     1081 gcattgcttg gcacaaggat gcaggactac ctgtgtatgc tcacatcagt cctacagata
     1141 tggaggccat ccccaaagcc actaccaatc caggtaaccg caaagtgaga gcacttgcct
     1201 tcagcaacaa aaaccaggag ctgggagctg tgtccttgga tggctacttc cacctgtgga
     1261 aagcccgaag ctccctgtct aggctgctat ccctgaggct gccctattgc cgtgagaacg
     1321 tgtgtctcac ctactgtgat gagttttccc tctacgcagt gggttctcag tctcacgttt
     1381 cgttcctgga tcttcgccaa ggccagcaga acatcccgcc actgtgctcc agagagggag
     1441 gcaccggtgt tcgttctctg agtgtccacc agcatattgt cactgtggga acaggccacg
     1501 gttctctgct cttctatgac atccgtgccc agaagttcct tgaggaaagg tccgcggcca
     1561 atccagacat gtttcctgtg ccctctggaa ggaagctcaa gctcacctgt ggcagtggct
     1621 ggatcaacca ggatgatctt ctagagaatt atgttgctgg tgtagaagat ttccccaatg
     1681 cgctctacac tcactgctac aactggccag agatgaagct tttcgtaggc gggggaccac
     1741 tggcgtcagg cctccatggc aactacgcag gcctctggag ctaaggtgga actgccccag
     1801 agtatccagt gtgcttctca gaagaaaaag agatggaacc cccagaagtc ggctttgaga
     1861 gttttctggg tctccccacc gttctttgga cttttcatgc atatactttc cactaattct
     1921 tagctgtgtt gtttttgagt gagtgatcca tgtagtctat tacggaagaa aatcctgtta
     1981 tgaagttaaa attgtgtaag tcttgtgtta ctattattag cagtttagtt ttcatcatgt
     2041 gtgagatatt aaggatattt tctaataaac agagtttgga catttgttca ggaatactaa
     2101 tcatagtttt gtagacttgt tccagtgtta aaaaaatgaa aaaagaaaaa aaaaacattc
     2161 catgttccag tttgcctact tttggaaatg tgtcattcat gaattgtgat catggtgtat
     2221 gtatatagtt tgtatgttgt tggtgcgaaa ctcacttttc taaaaagttt attatgtgga
     2281 aataattgtc gtagaatctt gtgtttctat caaaaatctc agatgacgag gatggtttag
     2341 gtattcaagt attctgctca tttgagtgtt gaagagtaat ccaaaactca gtgtttttct
     2401 ttcaagcctt attttcattt ttagtctctg tcttcatatt gatcaaagag tgcacttgtt
     2461 ttcacttctt gccttagtac tatcaagact tgtggatata tttgaatgct gtcatttgag
     2521 taaatttcac agagtttcag tgccatcatt cgacacaggg atattaagta cataaatgta
     2581 gaatgtatgg cagacagggc agaaaatata ctgctctaag gtatagactg gatatttttg
     2641 ctgttgctat ttttaatacc aaatgttata tttgagcata ttttaaactt tcaaaatctg
     2701 cttgtgagtt aaattgaaag aaaaaaaaag tgcaaaggaa gaagtctgag cctatccagc
     2761 tcactgtgag agaaactccc cctttgtaag ctccaaatgt ttattttgtg aacttgaaag
     2821 attcatactt caagtagaat agatctgtta ctaaacctct ggttctatgt cttgaaatgt
     2881 gataatatgg gatcttgaca atgcagtata attttcaaat agaggagctg gggattaaaa
     2941 agataggtct gattaaagga ctgtgcagtt cagataaata gagataatgg gatgccgtgc
     3001 ggatagattg gttttctccc taggtgagaa ggctgaaaat gagaaaggag ccaggccttg
     3061 cttaaagctg gttaggacgt gttaaccctg gattggtatt gggtcatgat tcctttttct
     3121 taaacatcaa acatgtattt tgcattggtg ttgatacact acatgttgtt cagtcctaaa
     3181 cctaaattgt tgaaaggatc taaaggtgag tcaagaatac acaatggtca gatttttggt
     3241 ttataaagat tatgcaggtc tatttcatag aattataaag ttttgcaact aatctgtgca
     3301 ttttcttgct tgcatgtatg tttctatctc tgctgcaaat gatttaaaag cagagattgt
     3361 aaactgccct cttttcttta tttgtatact aaggccgaac aaaggcaatc agtgattatt
     3421 tgatgatttt tcttttgcca atggaaacct gcactacaca ttgtaataaa tatttgctgt
     3481 tgcataataa agaaccttgt tctgtgttcc cc
//
