LOCUS       NM_153167               7226 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus DDB1 and CUL4 associated factor 10 (Dcaf10), mRNA.
ACCESSION   NM_153167
VERSION     NM_153167.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7226)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 7226)
  AUTHORS   Zhang,Y.L., Zhao,L.W., Zhang,J., Le,R., Ji,S.Y., Chen,C., Gao,Y.,
            Li,D., Gao,S. and Fan,H.Y.
  TITLE     DCAF13 promotes pluripotency by negatively regulating SUV39H1
            stability during early embryonic development
  JOURNAL   EMBO J 37 (18) (2018)
   PUBMED   30111536
REFERENCE   3  (bases 1 to 7226)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   4  (bases 1 to 7226)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 7226)
  AUTHORS   Lau,N.C., Seto,A.G., Kim,J., Kuramochi-Miyagawa,S., Nakano,T.,
            Bartel,D.P. and Kingston,R.E.
  TITLE     Characterization of the piRNA complex from rat testes
  JOURNAL   Science 313 (5785), 363-367 (2006)
   PUBMED   16778019
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY732400.1, AK083428.1, CN533345.1, AL772376.6 and BX526643.1.
            
            On Jul 28, 2006 this sequence version replaced NM_153167.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660815.161670.1, BC027317.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-627               BY732400.1         1-627
            628-1033            AK083428.1         229-634
            1034-1592           CN533345.1         118-676
            1593-6722           AL772376.6         19314-24443
            6723-7226           BX526643.1         9-512
FEATURES             Location/Qualifiers
     source          1..7226
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 23.87 cM"
     gene            1..7226
                     /gene="Dcaf10"
                     /gene_synonym="Wdr32"
                     /note="DDB1 and CUL4 associated factor 10"
                     /db_xref="GeneID:242418"
                     /db_xref="MGI:MGI:2140179"
     exon            1..627
                     /gene="Dcaf10"
                     /gene_synonym="Wdr32"
                     /inference="alignment:Splign:2.1.0"
     CDS             68..1768
                     /gene="Dcaf10"
                     /gene_synonym="Wdr32"
                     /note="WD repeat domain 32; WD repeat-containing protein
                     32"
                     /codon_start=1
                     /product="DDB1- and CUL4-associated factor 10"
                     /protein_id="NP_694807.2"
                     /db_xref="CCDS:CCDS38754.1"
                     /db_xref="GeneID:242418"
                     /db_xref="MGI:MGI:2140179"
                     /translation="MFPFGPHSPGGDETAGAEEPPPLGGPAAASRPPSPAPRPASPQR
                     GADAASPPPVAGSPRLPGGPAVSPAERAGEFAAPGALELSAATASASQAKLSPSSSPR
                     RRSRPDWRAGGRSRQGLGAGLGGPGARLFGWLRERSLGRGLFVDPARDNFRTMTNLYG
                     SIHPADSVYLSTRTHGAVFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHE
                     DCVNNIRFLDNRLFATCSDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLV
                     TSGFDGNVIIWDTNRCTEDGCPHKKFFHTRFLMRMRLTPDCSKMLISTSSGYLLILHE
                     LDLTKSLEVGSYPILRARRTTSSSDLTTTSSSSGSRVSGSPCHHNDSNSTEKHMSRAS
                     QREGVSPRNSLEVLTPEVPGERDRGNCITSLQLHPKGWATLLRCSSNTDDQEWTCVYE
                     FQEGAPVRPVSPRCSLRLTHYIEEANVGRGYIKELCFSPDGRMISSPHGYGIRLLGFD
                     KQCSELVDCLPKEASPLRVIRSLYSHNDVVLTTKFSPTHCQIASGCLSGRVSLYQPKF
                     "
     exon            628..741
                     /gene="Dcaf10"
                     /gene_synonym="Wdr32"
                     /inference="alignment:Splign:2.1.0"
     exon            742..939
                     /gene="Dcaf10"
                     /gene_synonym="Wdr32"
                     /inference="alignment:Splign:2.1.0"
     exon            940..1142
                     /gene="Dcaf10"
                     /gene_synonym="Wdr32"
                     /inference="alignment:Splign:2.1.0"
     exon            1143..1253
                     /gene="Dcaf10"
                     /gene_synonym="Wdr32"
                     /inference="alignment:Splign:2.1.0"
     exon            1254..1399
                     /gene="Dcaf10"
                     /gene_synonym="Wdr32"
                     /inference="alignment:Splign:2.1.0"
     exon            1400..7213
                     /gene="Dcaf10"
                     /gene_synonym="Wdr32"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2175..2180
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dcaf10"
                     /gene_synonym="Wdr32"
                     /note="hexamer: AATAAA"
     polyA_site      2202
                     /gene="Dcaf10"
                     /gene_synonym="Wdr32"
                     /note="major polyA site"
     regulatory      2397..2402
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dcaf10"
                     /gene_synonym="Wdr32"
                     /note="hexamer: ATTATA"
     polyA_site      2448
                     /gene="Dcaf10"
                     /gene_synonym="Wdr32"
ORIGIN      
        1 ggagcgggag cgctgagttg tcgggcggcg ggacagcggc ccggaatagg gggcgggggc
       61 gttggtcatg tttcccttcg ggccccacag cccgggcggg gacgagacgg ctggagccga
      121 ggagccgccg cctctcggag ggccggcggc agcttccaga ccgccctctc cagctccgcg
      181 accggcgtct ccgcagcgag gagctgacgc ggcctctccc ccgccggtcg ccgggagccc
      241 tcgcctcccg ggcggccccg cggtgtcccc agccgagcgc gccggagagt tcgcggctcc
      301 cggagctctg gagttgtccg ccgccaccgc gtcggcgtcg caggcaaagc tgtcaccctc
      361 ctcctcgccg cgcagacgct cgaggccgga ctggagggcg ggcgggcgga gccggcaggg
      421 cctcggcgca ggcctgggcg gccccggggc cagactgttc gggtggctga gagagcgaag
      481 cctcggtcgc gggctgttcg tggacccggc tcgggacaat ttccgcacga tgactaacct
      541 gtatgggtcc atccatcccg cagactcggt gtacctcagc acccgcaccc acggtgctgt
      601 cttcaacctc gagtactctc cggacgggtc agtgctgaca gtcgcttgtg aacagactga
      661 agttctgctt tttgacccta tatcttcaaa gcacataaaa accctttctg aagcacatga
      721 agattgtgtg aataatatca gatttcttga taaccggctc tttgctacct gctctgatga
      781 taccacaata gcactatggg atctgagaaa attgaacacc aaagtatgca ctttacatgg
      841 tcacactagc tgggtgaaga acatcgaata tgatactaat acaagactct tagtaacatc
      901 aggatttgat ggaaatgtca ttatttggga cactaacagg tgcacagaag atgggtgtcc
      961 acataagaaa ttctttcata cacgttttct catgagaatg agattaacac cagattgttc
     1021 caaaatgttg atctcaacat cctctggata cctcctgatc ttgcatgagc tggacttaac
     1081 taagtcttta gaagtaggca gctatcccat tttgagagca agaagaacta cttcaagttc
     1141 agatttgacc actacatcaa gttcttctgg ttctagagtt tctggttcac cttgtcatca
     1201 caatgattca aattcaactg agaaacacat gtctcgagcc tctcaacgag aaggagtttc
     1261 accacgaaat agtcttgaag tgttaacccc tgaagttcct ggtgagagag atcggggaaa
     1321 ctgtatcact tccttacagc tgcatcctaa gggctgggcc acccttcttc ggtgctcaag
     1381 caacactgat gatcaggagt ggacctgtgt ctatgaattc caggaaggag ctccagtgcg
     1441 accagtctcc cctcgatgtt ccctgcggtt gactcattac attgaggaag caaatgtggg
     1501 caggggctac atcaaagaac tttgtttcag ccctgatgga cgaatgattt cttccccaca
     1561 cggctatggg attcgcttgt tgggatttga caaacagtgc agtgagcttg ttgactgttt
     1621 acccaaagaa gccagtcccc tgcgggtgat tcgttctctg tactctcata atgacgtggt
     1681 tctgacaaca aagttctctc ccacacactg tcagatcgcc tcagggtgcc ttagtggacg
     1741 ggtctctttg tatcagccaa agttttaggc acaacttaca tcaaatgagg aactcttctg
     1801 gtgtttggct tataaattac ttcaatttag gtgaagtatt ttctttttta gaagatctta
     1861 taagtttgga tcaagatctt ggttcttatg ggtcagtgga catatatatg tgtgacctga
     1921 gtacttggcc ttccagcgtc atccgggcat ctccatttca accacgcagc ctgttctgtc
     1981 agcattcctt tgctcctgtc tgtgccgctg agcttgggtt ttcctggtca ttttgcatgt
     2041 ggctcttgtt ctccccatcc ctgtctccac cattcctctc tgcctccgtc ctcgtttttg
     2101 atttttggta tgaattttat ggacatttgg caggagcctt ggttgggatg agaaaaccca
     2161 tggcactagt gttaaataaa actcagaagt tggatgttgg cacactggtg attgaaaaag
     2221 ttcatcttca tttatcagta tacttggcct ttaaagttgc tgtcagacat tgagcacagt
     2281 aatagcattc tcataacttt tagaaactct tgcaacaaga tagcttttta aagtttcctg
     2341 ttaaaatgac acctttatat ctcatgtggg attttgttgt gaaattctag aaaaatatta
     2401 taacctctct ttgtaattta ttttacttgt atgaatttaa gatctccagc gtgtgtcttt
     2461 acttggtatt ctgttccggt cagcagcatt ggagaggaaa ggaagagcca taagcctggt
     2521 catttccgtt gtccagaaga tttatttact caggaggtcg gcacagcatc cggccagtga
     2581 gtgaggagat tgatgtgact taggttggct gtgagtcttt taatcacaca gatggtgtgt
     2641 ttatagtaat gaagtgggag ggaaatcaag taaagatttt attgtgtttg ttccttcaac
     2701 cagggatcag ttctcagaag ggagctagag tcctctttaa gctgctgtca taaacctaga
     2761 gtcagtgacc tgactgacac tgctgtcctg tgtttggcta tggaaggtct gggagacaac
     2821 gtgtaagccc aggctgctcc agtcttaaat gggcgatgtc ctgccaggct ctgctacatt
     2881 ggttggttgg tttgttgatt gactgactga ttgataattt aagccatgca gcagtagcct
     2941 tgttctcttt ggtcacgtgc cctttaggcc agtgctcctt taatattagg atgcagtaca
     3001 atgtaccctg aaggactagt aaaatgtgct ggaccttaag actgatttag gcagggaaag
     3061 aacagaactc ttatgtaaat ggaacctcaa atctgcatcc aggtggcctc taggccatag
     3121 tttaaaacac aacttggaat gcagtcgata tttctttatc catttggtgc ttaacataat
     3181 tctcacaaga tgtttcatct atttaaatag taataataat caatagtagc aattttagag
     3241 tagaaaataa cttgaagtga tatccaattc attgttggac aaatgcaaga agtcacatga
     3301 tttgcctatg gtcatacaaa gtctctcaat tccttgctca gggcttttaa aaacaccagt
     3361 gatcgtggac atcttgtctt tattattgta aatacgatga taggattgga aaaggagggc
     3421 atgggagtag atgctgagag ctttatccat aggaaagaag tattttagta cttgagaaat
     3481 tagcagccca tgtgtgagta aacacagcag ttctctctgt gcccatcaca cagccgctca
     3541 tacagccgga agcgcttgtg tctcactgag aacagtgata actctgcgac agtctcgaag
     3601 agtcaacact tcttaccaca gatgctggaa aagctggaaa tgttgtagtc attgaaacat
     3661 tcaaccaagc acaatggaaa tcataggctt gcttgccgta gctttggaaa aaggttgctt
     3721 tttgggtctt tttttttccc ccaaagaaaa tagtttggga ggaaagtata gcaattaata
     3781 ccttcacaat taaaaactat tatataagga tcaaattgat actcaaaaga agattccata
     3841 aatgatatca gtttgtaaag agttctatgt cagatgttat acccacatgt cacctaacgc
     3901 aagccaggga cccttgaatc actgttgctg aatacctact atgtgttgaa gaatgtgtct
     3961 gctttaatat actatgggcc cctacaaaga cccttacaag gtaggtggaa tgagcgtcaa
     4021 attatgttga aagtagcagt gtgttaaaaa atgaagtgac gtgccttcag ccacaggtgg
     4081 cagaggtggc agcactggat tcagatggag gtttgctgtc agttttattg ctgagactgc
     4141 actgactcct ctgcgttttg ccccttagtt catggaggag gagttacact ggtctgctgg
     4201 tccatgtgct tgctatcttc tgcaaagttt gatcacacag ttggcctcgt tcccttgagt
     4261 actgcataaa agaacatttc aagcactgat gttcccatga gactggagag cataaactca
     4321 ggccatttct aacagaaaaa ctatgcagat gagtccccat ggtggcgaaa aagtggatag
     4381 tcagccttgt gagaagcaaa gccagacaga tgagaagtga caagagccag caaactgagc
     4441 agggatccgt tgccctctct gaggaacagt caggatcaag acaaaatcag acagtactaa
     4501 gcaaggaatt gaacggcctc agaaaaacct gttctattgg gaagagttac atatcttaac
     4561 gtcccttttt gtttttattt tgtttttggc tttttgagac agggtttctt tgtatagacc
     4621 agactgcctt caaattcaca gatgtccacc tgcctctgcc ttccaagtgt tgggattaaa
     4681 gacatgtgcc accacagcct ggccttaggg tctcacttta atagtctaaa actatgttgt
     4741 ttttttttta ctgttttatt tagtcatttt tattataatt ggtagaaata tattttaatt
     4801 gataacgaag ttattactgt tggtaaagct tcctttggaa gagtctatta atgggaatgc
     4861 tatgttgaat gacttacaga tgtatcaaat atacagtagt tgcttatttt caatcatgaa
     4921 ataaagagct aaagtaagaa acttctactt taaaaaaaaa tattatgtga tcacaattcg
     4981 ggggccaggg gaacatatgc ttttaattcc agaagtgggg atgcagaggc aggaggatct
     5041 tctgtgagtt tgaggtcagc aggtctacat agtaaggttc tgggctagcc agagttatac
     5101 agtaagaccc tgcttattaa aaaaaaaaaa aaaagtcatt tttttcctca gaacccaaaa
     5161 catatgtata ttttattttt tctccccatt gtattcctaa gaaggcagca tagcaaaaaa
     5221 ttttagaaaa caacacaagg aaaatataaa tttcatattc tctactcctg catcgaggac
     5281 caaatcacat tttttaaggc tgtgccctct agaaggtgag aataaagaaa tacatcaaga
     5341 atcttttaga aggtgggtgt ttctaatact ggagtatgca gcagtgtcca taagagtctg
     5401 ttacacttgg cttttatttt tatttatttt ttgagacaag atttctctgt gtagccttgg
     5461 ctgtcttaga actcactttg ttacccaggc tggcccacaa ctcagtttcc cttgcctttg
     5521 cctaccaaat gctgagatta aaggtatgta cctttaatcg ctggctttca tttggctttt
     5581 atgaaagcag gagacatggc ctgataactt cctgatgaca atcatcttta tcctgtacca
     5641 gtggtcttgg tccactcagt aacaccttct gttggtcatg aaggaatcca tatatatgac
     5701 ttctgtttag ataactaatg catatctttt taagtgccaa aatttaaaaa tttcagttat
     5761 ttttttgatg caagtctcct tagggatggt agtctacctc cctgcctttt taaacagctt
     5821 gctcagtcga attcacttca tcatgaagtt atattcatga tgttttattg cgcatgccca
     5881 gtgcggtctg gtccacataa aacagtaaaa catttcatag cacacaaagg gctataacag
     5941 attcgaggaa tatccaccta gtaagtgatt ccctcaacga tggaattatt tccctcagta
     6001 ttagctttaa aaagtgtttg atgtctgcag agtaatgcat tctatcagtg tgcctgtttc
     6061 taacaggctc ccactttctt ctgtgctgtc tcccaagttc tgggctgtga catgaactga
     6121 ccagttctgg tcagtgccta caaaataact ggaccaaagc tcccagttaa aggtggggct
     6181 ctaaccaagt aaggggagga agtatgagta tacactgctg ctgctggagt ggagtgtggt
     6241 gatgatgatg cctctgcagg gaggcaggcc ttcatccttt taagagcaaa gaagcgtgca
     6301 gaagagaaag gaaggaaaag gaaaatcgag gtaggccgaa gactctggga gatggcactg
     6361 aataaccatt aaaatgtact cttgattacc atgttaaagt cagtttagtg acactgtaga
     6421 gtaaggctgc actatgtgta catcctctgg agaactcgag actgtgtata tcctgagaac
     6481 tgcacccctc cgaatggtaa tggaaatcag caccaagagg aaagtctcca gtttgcctgt
     6541 gtgctgctgt cttgagttgt aaattacctg agagaggttt aatcaaaagt cccagggcct
     6601 ggagaaacgg ctcagcggtt aagagcactg gctgctcttc cagaggtcct gagttcaatt
     6661 cccagcaacc acatggtggc tcacaaccat ctgtaatggg atccaatgcc ctcttctggt
     6721 gtgtctgaag acagctacag tgtgctcata cataattaat tttaaaaaaa aagtcccaag
     6781 gagcacatct catgcagaca ttttttgaat gtatgtatat ataaatgtca ctgtaagtga
     6841 cgcttacccc taagaataat aaagtaacat tcaggattta gatctggtcc caatctgtat
     6901 tttcccctat acaaagaata gatgtttgaa ttttctttta aatttggctg catccttcat
     6961 ttccaaactc tgcttctttt tttgggggcg gggggcacaa aactttaggt ttgtattttt
     7021 ggcaagcttg gaatattcta gttaatatgc tgtcagctag aacactctct tagcaggttc
     7081 taaggtgcta ttgggtcttc tgctagactg tgcgctcctt gagggcaggg ctatctttat
     7141 tcttgtatcc acggtgcctg ggatagtatc tgacagagta gttgttcaat aaatatctgt
     7201 tgaatgaatt gaaaaaaaaa aaaaaa
//
