LOCUS       NM_001005232            2096 bp    mRNA    linear   ROD 25-FEB-2025
DEFINITION  Mus musculus developing brain homeobox 1 (Dbx1), mRNA.
ACCESSION   NM_001005232 XM_145620
VERSION     NM_001005232.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2096)
  AUTHORS   Dudukcu,O., Raj,D.D.A., van de Haar,L.L., Grossouw,L.M.,
            Linders,L.E., Garritsen,O., Adolfs,Y., van Kronenburg,N.C.H.,
            Broekhoven,M.H., Kapteijns,T.H.W., Meye,F.J. and Pasterkamp,R.J.
  TITLE     Molecular diversity and migration of GABAergic neurons in the
            developing ventral midbrain
  JOURNAL   iScience 27 (11), 111239 (2024)
   PUBMED   39569362
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2096)
  AUTHORS   Bush,N.E. and Ramirez,J.M.
  TITLE     Latent neural population dynamics underlying breathing,
            opioid-induced respiratory depression and gasping
  JOURNAL   Nat Neurosci 27 (2), 259-271 (2024)
   PUBMED   38182835
REFERENCE   3  (bases 1 to 2096)
  AUTHORS   Prakash,N., Matos,H.Y., Sebaoui,S., Tsai,L., Tran,T.,
            Aromolaran,A., Atrachji,I., Campbell,N., Goodrich,M.,
            Hernandez-Pineda,D., Herrero,M.J., Hirata,T., Lischinsky,J.,
            Martinez,W., Torii,S., Yamashita,S., Hosseini,H., Sokolowski,K.,
            Esumi,S., Kawasawa,Y.I., Hashimoto-Torii,K., Jones,K.S. and
            Corbin,J.G.
  TITLE     Connectivity and molecular profiles of Foxp2- and Dbx1-lineage
            neurons in the accessory olfactory bulb and medial amygdala
  JOURNAL   J Comp Neurol 532 (2), e25545 (2024)
   PUBMED   37849047
REFERENCE   4  (bases 1 to 2096)
  AUTHORS   Tran,H.N., Nguyen,Q.H. and Jeong,Y.
  TITLE     Dbx1 is a dorsal midbrain-specific determinant of GABAergic neuron
            fate and regulates differentiation of the dorsal midbrain into the
            inferior and superior colliculi
  JOURNAL   Front Cell Dev Biol 12, 1336308 (2024)
   PUBMED   38344749
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2096)
  AUTHORS   Vermeiren,S., Cabochette,P., Dannawi,M., Desiderio,S., San
            Jose,A.S., Achouri,Y., Kricha,S., Sitte,M., Salinas-Riester,G.,
            Vanhollebeke,B., Brunet,J.F. and Bellefroid,E.J.
  TITLE     Prdm12 represses the expression of the visceral neuron determinants
            Phox2a/b in developing somatosensory ganglia
  JOURNAL   iScience 26 (12), 108364 (2023)
   PUBMED   38025786
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2096)
  AUTHORS   Weiss,K.M., Bollekens,J., Ruddle,F.H. and Takashita,K.
  TITLE     Distal-less and other homeobox genes in the development of the
            dentition
  JOURNAL   J Exp Zool 270 (3), 273-284 (1994)
   PUBMED   7964557
REFERENCE   7  (bases 1 to 2096)
  AUTHORS   Lu,S., Wise,T.L. and Ruddle,F.H.
  TITLE     Mouse homeobox gene Dbx: sequence, gene structure and expression
            pattern during mid-gestation
  JOURNAL   Mech Dev 47 (2), 187-195 (1994)
   PUBMED   7811640
REFERENCE   8  (bases 1 to 2096)
  AUTHORS   Johnson,K.R., Lu,S., Murtha,M.T., Ruddle,F.H. and Davisson,M.T.
  TITLE     Genetic mapping of a new homeobox gene to mouse chromosome 7
  JOURNAL   Genomics 14 (4), 1107-1109 (1992)
   PUBMED   1362181
REFERENCE   9  (bases 1 to 2096)
  AUTHORS   Lu,S., Bogarad,L.D., Murtha,M.T. and Ruddle,F.H.
  TITLE     Expression pattern of a murine homeobox gene, Dbx, displays extreme
            spatial restriction in embryonic forebrain and spinal cord
  JOURNAL   Proc Natl Acad Sci U S A 89 (17), 8053-8057 (1992)
   PUBMED   1355604
REFERENCE   10 (bases 1 to 2096)
  AUTHORS   Murtha,M.T., Leckman,J.F. and Ruddle,F.H.
  TITLE     Detection of homeobox genes in development and evolution
  JOURNAL   Proc Natl Acad Sci U S A 88 (23), 10711-10715 (1991)
   PUBMED   1720547
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC082541.1.
            
            On Sep 23, 2004 this sequence version replaced XM_145620.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC082541.1, SRR7652917.1073826.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164142 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2096
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 31.44 cM"
     gene            1..2096
                     /gene="Dbx1"
                     /gene_synonym="Dbx"
                     /note="developing brain homeobox 1"
                     /db_xref="GeneID:13172"
                     /db_xref="MGI:MGI:94867"
     exon            1..487
                     /gene="Dbx1"
                     /gene_synonym="Dbx"
                     /inference="alignment:Splign:2.1.0"
     CDS             121..1128
                     /gene="Dbx1"
                     /gene_synonym="Dbx"
                     /note="developing brain homeobox protein 1; Mmox C"
                     /codon_start=1
                     /product="homeobox protein DBX1"
                     /protein_id="NP_001005232.1"
                     /db_xref="CCDS:CCDS21306.1"
                     /db_xref="GeneID:13172"
                     /db_xref="MGI:MGI:94867"
                     /translation="MMFPGLLAPPAGYPSLLRPTPTLTLPQSLQSAFSGHSSFLVEDL
                     IRISRPPTYLSRSIPAASLSPPSQEAPAALADSGTSDLGSPGSGSRRGSSPQTALSPA
                     SEPTFLKFGVNAILSSAPRRETSPALLQSPPPKTFAFPYFEGSFQPFIRSSYFPASSS
                     VVPIPGTFSWPLAARGKPRRGMLRRAVFSDVQRKALEKTFQKQKYISKPDRKKLASKL
                     GLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSDVGQKGPGDE
                     EEDNPGARLAYHAPADPRHLLEGPLPASPAHSSSPGKPSDFSDSDEDEEGEEDEEITV
                     S"
     exon            488..589
                     /gene="Dbx1"
                     /gene_synonym="Dbx"
                     /inference="alignment:Splign:2.1.0"
     exon            590..792
                     /gene="Dbx1"
                     /gene_synonym="Dbx"
                     /inference="alignment:Splign:2.1.0"
     exon            793..2077
                     /gene="Dbx1"
                     /gene_synonym="Dbx"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcccaagta ggacggttac caggatactg agccaaagag ggcatcgggg gaggggcggg
       61 aagccaggcg cttgccctcc ggcccaggga aagggagcta ctgccagacc cgctctaacc
      121 atgatgttcc ccggcctcct tgcgcctccc gcgggatacc ctagcctcct gcgacccacg
      181 cccaccttaa cactgcccca gtcccttcaa tccgcatttt ccggccactc tagtttccta
      241 gtagaagatt tgatccgcat cagccggcct cccacctacc tgtcccgcag catacccgct
      301 gccagcctgt caccccccag tcaagaggcc cctgcagccc tcgccgactc ggggacctca
      361 gacctgggct ctcctgggtc cgggagccgg cgaggcagtt ctccacagac cgccctctcc
      421 cctgccagcg agcccacgtt tctgaagttt ggggtgaatg ccatcctttc ctcggcgcct
      481 agaagagaaa cttcgcccgc tttgctgcag agccctcctc ccaagacgtt cgcctttcca
      541 tacttcgaag gctcgttcca accctttatc agatcctcct atttcccagc ttcctccagc
      601 gtcgtgccta tccctgggac cttctcctgg ccgctggctg ctcgcggcaa gcctcgccgg
      661 ggcatgctgc gcagagccgt gttctctgac gtgcagcgga aagccctgga gaagacgttc
      721 cagaagcaga agtacatcag caagccagac cggaaaaagc tggcctccaa gcttggcttg
      781 aaggactcgc aggtgaaaat ctggttccag aatcgacgca tgaaatggcg gaactccaaa
      841 gagcgcgagc tcctgtctag cgggggctgc cgagagcaga cccttcccac aaaactaaac
      901 ccccatccag accttagtga tgtaggccag aagggacctg gggatgagga ggaagacaat
      961 ccgggtgccc gcctggccta ccacgcgccc gcagacccgc gacatttgct ggaagggcca
     1021 ctgcctgcct cgccggcgca ctcgagcagc ccgggtaaac cgtcagactt ctctgattct
     1081 gatgaggatg aggagggcga ggaggatgag gaaatcacgg tgtcctagga gcccctccag
     1141 cggctctggg gctgttgcaa ttggaaactg gagagggaac gcccacgtgg ccacctctgt
     1201 tcaggatcct ggatcctgcc tcttctcaca acagacccac caccttctca ggggtggcat
     1261 cacccttcct gttgtcccag agacatttcc ttgcgccgtg ctgccacctc taaacaaccc
     1321 ttcccacggg agcgtgggtc ttttctacaa gagcaacatt gcatctattt attgcaaatt
     1381 tattttagac accgcgtgca gggtgtgtgt agaggggtgt ccctagttcc actgccagtg
     1441 cttactgtga gccaggtcct gtcaaacacc aagcctctga cccctaactt cctggatggc
     1501 cacctttctg cagggggtat cagtcagcca tcctgtcttt tcaccttgag agtagaaagc
     1561 acaggagatt ctgaaagaga ataagggcac cgtctccctg tctaagggga aagcactatc
     1621 aagcaagctt ttcatttctt gatgctcctt tggcgggagg aagcgatttc tctctgtaga
     1681 catgtgtatc cagtgctctg cttgatgtcc ttctgctact ccaacgggag ccttttcaga
     1741 gtgccagctc ctggcactgg ggtgtggact tgtctgactc tccgacacgt ttcacccagc
     1801 tttgcagtct gggcagctta cctgagatgt gctctactgt gtatctatat tttgtatgga
     1861 tgttttatac tgaggttatt gtgaatgacc ataatgaagg gctggctgtg tccctctcat
     1921 tatttttctc tgcaatggtc tttaaagtct aaaaggtagc tgtgtaactt cataatttat
     1981 aaggaaatgc ttattttgta ttttttacca tgtacagact ttttatatat gtatatatgt
     2041 atcaaatgga caaatgccaa ataaaaagta gaatgagaaa aaaaaaaaaa aaaaaa
//
