LOCUS       NM_016974               1643 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus D site albumin promoter binding protein (Dbp),
            transcript variant 1, mRNA.
ACCESSION   NM_016974
VERSION     NM_016974.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1643)
  AUTHORS   Valakh,V., Wise,D., Zhu,X.A., Sha,M., Fok,J., Van Hooser,S.D.,
            Schectman,R., Cepeda,I., Kirk,R., O'Toole,S.M. and Nelson,S.B.
  TITLE     A transcriptional constraint mechanism limits the homeostatic
            response to activity deprivation in mammalian neocortex
  JOURNAL   Elife 12, e74899 (2023)
   PUBMED   36749029
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1643)
  AUTHORS   Martinez,M.E., Pinz,I., Preda,M., Norton,C.R., Gridley,T. and
            Hernandez,A.
  TITLE     DIO3 protects against thyrotoxicosis-derived cranio-encephalic and
            cardiac congenital abnormalities
  JOURNAL   JCI Insight 7 (21), e161214 (2022)
   PUBMED   36166296
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1643)
  AUTHORS   Park,S.A., Lim,Y.J., Ku,W.L., Zhang,D., Cui,K., Tang,L.Y., Chia,C.,
            Zanvit,P., Chen,Z., Jin,W., Wang,D., Xu,J., Liu,O., Wang,F.,
            Cain,A., Guo,N., Nakatsukasa,H., Wu,C., Zhang,Y.E., Zhao,K. and
            Chen,W.
  TITLE     Opposing functions of circadian protein DBP and atypical E2F family
            E2F8 in anti-tumor Th9 cell differentiation
  JOURNAL   Nat Commun 13 (1), 6069 (2022)
   PUBMED   36241625
  REMARK    GeneRIF: Opposing functions of circadian protein DBP and atypical
            E2F family E2F8 in anti-tumor Th9 cell differentiation.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1643)
  AUTHORS   Smith,C.B., van der Vinne,V., McCartney,E., Stowie,A.C.,
            Leise,T.L., Martin-Burgos,B., Molyneux,P.C., Garbutt,L.A.,
            Brodsky,M.H., Davidson,A.J., Harrington,M.E., Dallmann,R. and
            Weaver,D.R.
  TITLE     Cell-Type-Specific Circadian Bioluminescence Rhythms in Dbp
            Reporter Mice
  JOURNAL   J Biol Rhythms 37 (1), 53-77 (2022)
   PUBMED   35023384
REFERENCE   5  (bases 1 to 1643)
  AUTHORS   Tam,S.K.E., Brown,L.A., Wilson,T.S., Tir,S., Fisk,A.S.,
            Pothecary,C.A., van der Vinne,V., Foster,R.G., Vyazovskiy,V.V.,
            Bannerman,D.M., Harrington,M.E. and Peirson,S.N.
  TITLE     Dim light in the evening causes coordinated realignment of
            circadian rhythms, sleep, and short-term memory
  JOURNAL   Proc Natl Acad Sci U S A 118 (39) (2021)
   PUBMED   34556572
REFERENCE   6  (bases 1 to 1643)
  AUTHORS   Stubbs,L., Carver,E.A., Shannon,M.E., Kim,J., Geisler,J.,
            Generoso,E.E., Stanford,B.G., Dunn,W.C., Mohrenweiser,H.,
            Zimmermann,W., Watt,S.M. and Ashworth,L.K.
  TITLE     Detailed comparative map of human chromosome 19q and related
            regions of the mouse genome
  JOURNAL   Genomics 35 (3), 499-508 (1996)
   PUBMED   8812484
REFERENCE   7  (bases 1 to 1643)
  AUTHORS   Fonjallaz,P., Ossipow,V., Wanner,G. and Schibler,U.
  TITLE     The two PAR leucine zipper proteins, TEF and DBP, display similar
            circadian and tissue-specific expression, but have different target
            promoter preferences
  JOURNAL   EMBO J 15 (2), 351-362 (1996)
   PUBMED   8617210
REFERENCE   8  (bases 1 to 1643)
  AUTHORS   Stubbs,L., Carver,E., Ashworth,L. and Lopez-Molina,L.
  TITLE     Location of the DBP transcription factor gene in human and mouse
  JOURNAL   Mamm Genome 7 (1), 65-67 (1996)
   PUBMED   8903733
REFERENCE   9  (bases 1 to 1643)
  AUTHORS   Szpirer,C., Riviere,M., Cortese,R., Nakamura,T., Islam,M.Q.,
            Levan,G. and Szpirer,J.
  TITLE     Chromosomal localization in man and rat of the genes encoding the
            liver-enriched transcription factors C/EBP, DBP, and HNF1/LFB-1
            (CEBP, DBP, and transcription factor 1, TCF1, respectively) and of
            the hepatocyte growth factor/scatter factor gene (HGF)
  JOURNAL   Genomics 13 (2), 293-300 (1992)
   PUBMED   1535333
REFERENCE   10 (bases 1 to 1643)
  AUTHORS   Drolet,D.W., Scully,K.M., Simmons,D.M., Wegner,M., Chu,K.T.,
            Swanson,L.W. and Rosenfeld,M.G.
  TITLE     TEF, a transcription factor expressed specifically in the anterior
            pituitary during embryogenesis, defines a new class of leucine
            zipper proteins
  JOURNAL   Genes Dev 5 (10), 1739-1753 (1991)
   PUBMED   1916262
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC167242.4.
            
            On Sep 28, 2022 this sequence version replaced NM_016974.3.
            
            Summary: The protein encoded by this gene is a member of the Par
            bZIP transcription factor family and binds to specific sequences in
            the promoters of several genes, such as albumin, Cyp2a4, and
            Cyp2a5. The encoded protein can bind DNA as a homo- or heterodimer
            and is involved in the regulation of some circadian rhythym genes.
            [provided by RefSeq, Feb 2014].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC018323.1, AK140243.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-529               AC167242.4         105894-106422
            530-940             AC167242.4         107266-107676
            941-1152            AC167242.4         108920-109131
            1153-1643           AC167242.4         110325-110815
FEATURES             Location/Qualifiers
     source          1..1643
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 29.45 cM"
     gene            1..1643
                     /gene="Dbp"
                     /note="D site albumin promoter binding protein"
                     /db_xref="GeneID:13170"
                     /db_xref="MGI:MGI:94866"
     exon            1..529
                     /gene="Dbp"
                     /inference="alignment:Splign:2.1.0"
     CDS             391..1368
                     /gene="Dbp"
                     /note="isoform 1 is encoded by transcript variant 1; d
                     site-binding protein; albumin D box-binding protein;
                     albumin D-element-binding protein"
                     /codon_start=1
                     /product="D site-binding protein isoform 1"
                     /protein_id="NP_058670.2"
                     /db_xref="CCDS:CCDS21260.1"
                     /db_xref="GeneID:13170"
                     /db_xref="MGI:MGI:94866"
                     /translation="MARPLSDRTPGPLLLGGPAGAPPGGGALLGLRSLLQGNSKPKEP
                     ASCLLKEKERKATLPSAPVPGPGLETAGPADAPSGAVSGGGSPRGRSGPVAGPSLFAP
                     LLWERTLPFGDVEYVDLDAFLLEHGLPPSPPPPGGLSPAPSPARTPAPSPGPGSCSSS
                     SPRSSPGHAPARATLGAAGGHRAGLTSRDTPSPVDPDTVEVLMTFEPDPADLALSSIP
                     GHETFDPRRHRFSEEELKPQPIMKKARKVQVPEEQKDEKYWSRRYKNNEAAKRSRDAR
                     RLKENQISVRAAFLEKENALLRQEVVAVRQELSHYRAVLSRYQAQHGTL"
     exon            530..940
                     /gene="Dbp"
                     /inference="alignment:Splign:2.1.0"
     exon            941..1152
                     /gene="Dbp"
                     /inference="alignment:Splign:2.1.0"
     exon            1153..1643
                     /gene="Dbp"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1492..1497
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dbp"
                     /note="hexamer: AATACA"
     polyA_site      1516
                     /gene="Dbp"
                     /note="major polyA site"
     regulatory      1622..1627
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dbp"
                     /note="hexamer: AATAAA"
     polyA_site      1643
                     /gene="Dbp"
                     /note="major polyA site"
ORIGIN      
        1 gtgcagattg caaagctcct ttctttgcga gaagtgcaaa attggctaga gccagagact
       61 cgcccacttg gtacagaagg agcgcgcgcc tgtgtccctt ggggacccac agttgcaaag
      121 agacagctgc ttgatttggt cacccactcg cccagactat aggagcctcc cgggacagtc
      181 tttgagttgc acctttctgc agaactgact ggttgaaccc ccgcagcgct cttaggattt
      241 gaagcgtcct gatcctggag gcttgcacgc cgcgctctcc cgactctggg acacattcgc
      301 ccgaaccact ggagtgtgcg ggtgactgac atatcatctc atctcttcga ctctccatga
      361 gctcatgaac ctgggagcag gtccacggca atggcgcggc ctctgagcga caggaccccg
      421 ggccccctgc tgctgggtgg cccggctggg gccccccctg gcgggggagc gctgcttggg
      481 ctgaggagcc ttctgcaggg aaacagcaag cccaaagaac cggccagctg tctcctgaag
      541 gaaaaggagc gcaaggcaac tctgccctca gcccccgtcc cgggacccgg cctggaaacg
      601 gcgggcccag ccgatgcccc gagtggggcc gttagtggcg gtgggtcccc tcgggggcgc
      661 tcagggcctg tggctggccc gagtcttttt gcgccgctgc tgtgggaacg cactttgcct
      721 ttcggggacg tggaatacgt ggacctggac gccttcttgc tggagcacgg gctaccgccg
      781 agcccgccgc cccccggggg cctgtcgccg gcaccctctc cagcgcgcac tcccgcgccc
      841 tcccccgggc ccggctcttg cagctcctct tccccccgct cctcgcccgg gcacgccccc
      901 gcgcgggcca ctctgggagc cgccggcggc caccgcgcag gcttgacatc tagggacaca
      961 cccagtcctg tggacccaga caccgtggag gtgctaatga cctttgaacc tgatcccgct
     1021 gatctcgccc tgtcaagcat tccaggccat gagacttttg accctcggag acaccgcttc
     1081 tcagaggagg aactgaagcc tcaaccaatc atgaagaagg caaggaaagt ccaggtgcct
     1141 gaggaacaga aggatgagaa gtactggagc cggaggtaca agaacaatga agcagccaag
     1201 aggtcgagag atgcaagaag actcaaggag aaccagatat ctgtgcgggc tgccttcctg
     1261 gagaaggaaa acgccctgtt gcggcaggag gtggtggctg tgcggcagga gctgtcccac
     1321 taccgtgctg tgctttcacg ctaccaggcc cagcatggga cactgtgagg ccacctccac
     1381 cctgccaggg cagagtcctg ttccttgctc agacttacac ctgacttcct ccttgtccca
     1441 tggccagtgg tctggccagc taggtgcccg aagaacgtca tgatgcagac aaatacattt
     1501 atatttttaa gaaaaagcta gccttccccc acctcccttg tgggggtggg gagggtcctg
     1561 tgtgtgctct tagcatgttg gggaacccat ccatccaacc gcctccatca acacaatcct
     1621 gaataaatct tgagaacccg gga
//
