LOCUS       NM_001146309            2357 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus drebrin-like (Dbnl), transcript variant 3, mRNA.
ACCESSION   NM_001146309
VERSION     NM_001146309.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2357)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2357)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2357)
  AUTHORS   Inoue,S., Hayashi,K., Fujita,K., Tagawa,K., Okazawa,H., Kubo,K.I.
            and Nakajima,K.
  TITLE     Drebrin-like (Dbnl) Controls Neuronal Migration via Regulating
            N-Cadherin Expression in the Developing Cerebral Cortex
  JOURNAL   J Neurosci 39 (4), 678-691 (2019)
   PUBMED   30504273
  REMARK    GeneRIF: the novel protein Dbnl, an actin-binding protein, controls
            multiple events during neuronal migration in the developing mouse
            cerebral cortex
REFERENCE   4  (bases 1 to 2357)
  AUTHORS   Seeley-Fallen,M.K., Liu,L.J., Shapiro,M.R., Onabajo,O.O.,
            Palaniyandi,S., Zhu,X., Tan,T.H., Upadhyaya,A. and Song,W.
  TITLE     Actin-binding protein 1 links B-cell antigen receptors to negative
            signaling pathways
  JOURNAL   Proc Natl Acad Sci U S A 111 (27), 9881-9886 (2014)
   PUBMED   24958882
REFERENCE   5  (bases 1 to 2357)
  AUTHORS   Haag,N., Schwintzer,L., Ahuja,R., Koch,N., Grimm,J., Heuer,H.,
            Qualmann,B. and Kessels,M.M.
  TITLE     The actin nucleator Cobl is crucial for Purkinje cell development
            and works in close conjunction with the F-actin binding protein
            Abp1
  JOURNAL   J Neurosci 32 (49), 17842-17856 (2012)
   PUBMED   23223303
REFERENCE   6  (bases 1 to 2357)
  AUTHORS   Engqvist-Goldstein,A.E., Kessels,M.M., Chopra,V.S., Hayden,M.R. and
            Drubin,D.G.
  TITLE     An actin-binding protein of the Sla2/Huntingtin interacting protein
            1 family is a novel component of clathrin-coated pits and vesicles
  JOURNAL   J Cell Biol 147 (7), 1503-1518 (1999)
   PUBMED   10613908
REFERENCE   7  (bases 1 to 2357)
  AUTHORS   Lee,C.G., Morse,H.C. 3rd, Kay,B.K. and Kozak,C.A.
  TITLE     Genetic mapping of eight SH3 domain genes on seven mouse
            chromosomes
  JOURNAL   Mamm Genome 10 (4), 402-404 (1999)
   PUBMED   10087302
REFERENCE   8  (bases 1 to 2357)
  AUTHORS   Larbolette,O., Wollscheid,B., Schweikert,J., Nielsen,P.J. and
            Wienands,J.
  TITLE     SH3P7 is a cytoskeleton adapter protein and is coupled to signal
            transduction from lymphocyte antigen receptors
  JOURNAL   Mol Cell Biol 19 (2), 1539-1546 (1999)
   PUBMED   9891087
REFERENCE   9  (bases 1 to 2357)
  AUTHORS   Yamabhai,M. and Kay,B.K.
  TITLE     Examining the specificity of Src homology 3 domain--ligand
            interactions with alkaline phosphatase fusion proteins
  JOURNAL   Anal Biochem 247 (1), 143-151 (1997)
   PUBMED   9126384
REFERENCE   10 (bases 1 to 2357)
  AUTHORS   Sparks,A.B., Hoffman,N.G., McConnell,S.J., Fowlkes,D.M. and
            Kay,B.K.
  TITLE     Cloning of ligand targets: systematic isolation of SH3
            domain-containing proteins
  JOURNAL   Nat Biotechnol 14 (6), 741-744 (1996)
   PUBMED   9630982
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY293844.1, AK053796.1 and BM247511.2.
            
            Transcript Variant: This variant (3) uses a different splice site
            in its 3' coding region, compared to variant 1. The resulting
            protein (isoform 2) is shorter when it is compared to isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK159984.1, AK168898.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-5                 BY293844.1         2-6
            6-1897              AK053796.1         2-1893
            1898-2357           BM247511.2         1-460               c
FEATURES             Location/Qualifiers
     source          1..2357
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 3.87 cM"
     gene            1..2357
                     /gene="Dbnl"
                     /gene_synonym="Abp1; mAbp1; SH3P7"
                     /note="drebrin-like"
                     /db_xref="GeneID:13169"
                     /db_xref="MGI:MGI:700006"
     exon            1..160
                     /gene="Dbnl"
                     /gene_synonym="Abp1; mAbp1; SH3P7"
                     /inference="alignment:Splign:2.1.0"
     exon            161..216
                     /gene="Dbnl"
                     /gene_synonym="Abp1; mAbp1; SH3P7"
                     /inference="alignment:Splign:2.1.0"
     exon            217..329
                     /gene="Dbnl"
                     /gene_synonym="Abp1; mAbp1; SH3P7"
                     /inference="alignment:Splign:2.1.0"
     exon            330..404
                     /gene="Dbnl"
                     /gene_synonym="Abp1; mAbp1; SH3P7"
                     /inference="alignment:Splign:2.1.0"
     exon            405..551
                     /gene="Dbnl"
                     /gene_synonym="Abp1; mAbp1; SH3P7"
                     /inference="alignment:Splign:2.1.0"
     exon            552..629
                     /gene="Dbnl"
                     /gene_synonym="Abp1; mAbp1; SH3P7"
                     /inference="alignment:Splign:2.1.0"
     exon            630..781
                     /gene="Dbnl"
                     /gene_synonym="Abp1; mAbp1; SH3P7"
                     /inference="alignment:Splign:2.1.0"
     exon            782..830
                     /gene="Dbnl"
                     /gene_synonym="Abp1; mAbp1; SH3P7"
                     /inference="alignment:Splign:2.1.0"
     exon            831..924
                     /gene="Dbnl"
                     /gene_synonym="Abp1; mAbp1; SH3P7"
                     /inference="alignment:Splign:2.1.0"
     exon            925..1020
                     /gene="Dbnl"
                     /gene_synonym="Abp1; mAbp1; SH3P7"
                     /inference="alignment:Splign:2.1.0"
     exon            1021..1130
                     /gene="Dbnl"
                     /gene_synonym="Abp1; mAbp1; SH3P7"
                     /inference="alignment:Splign:2.1.0"
     exon            1131..1236
                     /gene="Dbnl"
                     /gene_synonym="Abp1; mAbp1; SH3P7"
                     /inference="alignment:Splign:2.1.0"
     exon            1237..2357
                     /gene="Dbnl"
                     /gene_synonym="Abp1; mAbp1; SH3P7"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1835
                     /gene="Dbnl"
                     /gene_synonym="Abp1; mAbp1; SH3P7"
                     /note="major polyA site"
     regulatory      2336..2341
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dbnl"
                     /gene_synonym="Abp1; mAbp1; SH3P7"
                     /note="hexamer: TATAAA"
     polyA_site      2353
                     /gene="Dbnl"
                     /gene_synonym="Abp1; mAbp1; SH3P7"
                     /note="major polyA site"
ORIGIN      
        1 ggggcggggc ttccggccgt cactggaggc cggcagaaag ctgaagctgc tgcatcgcgg
       61 ggaccgtggg gcgtgccatg gcggtgaacc tgagccggaa cgggccggcg ctgcaggagg
      121 cctacgtgcg cgtagtcacc gagaaatccc cgaccgactg ggctcttttt acctatgaag
      181 gcaacagcaa tgacatccgt gtggctggca caggagaggg aggcctggag gagctggtgg
      241 aagagctcaa cagcgggaag gtgatgtacg ccttctgcag ggtgaaggac cccaactccg
      301 gcctgcccaa gtttgtcctc atcaactgga caggagaggg tgtgaatgat gtgcggaaag
      361 gagcatgtgc caaccacgtc agcaccatgg ccaacttcct gaagggtgcc cacgtgacca
      421 tcaatgcccg ggccgaggag gatgtggagc ctgagtgcat catggagaag gttgccaagg
      481 cctctggggc caactacagc ttccataagg aaagcacctc cttccaggat gtagggccgc
      541 aggccccagt gggctctgtg taccagaaga ccaatgccat atctgagatc aagagagtcg
      601 gcaaggataa cttctgggcc aaagctgaga aggaagaaga gaaccgccgc ctggaggaga
      661 agcggcgtgc cgaagaggag cggcagcggt tggaggagga gcgacgagag cgggagctgc
      721 aggaggctgc ccgacgtgag cagcgctacc aggaacagca cagatcagct ggagccccga
      781 ggacaggtga gccagagcag gaagccgttt caaggaccag acaggagtgg gagtctgctg
      841 ggcagcaggc cccacaccca cgagagattt tcaagcagaa ggaaagggca atgtccacca
      901 cctctgtcac cagctcgcag ccgggcaagc tgaggagccc cttcctgcag aagcaactca
      961 ctcaaccaga aacctcctac ggccgagagc ccacagctcc tgtctcccgg cctgcagcag
     1021 gtgtctgtga ggagccagcg cctagcactc tgtcttctgc ccagacagaa gaagaaccta
     1081 catatgaagt acccccagag caggacaccc tctatgagga accaccactg gtacagcagc
     1141 aaggggctgg ctccgaacac attgacaact acatgcagag ccagggcttc agtggacaag
     1201 ggctgtgcgc ccgggccttg tatgactacc aggcagctga tgacaccgag atctcctttg
     1261 accctgagaa cctaatcaca ggcatcgagg tgattgacga aggctggtgg cgaggctatg
     1321 ggcctgacgg ccactttggc atgtttcctg ccaactacgt ggagctcata gagtgaggcc
     1381 gagacctggc gtccttctcc accacaagtg gattccttgt cgcctaagga ggaggccaaa
     1441 gaattaatat ttggcactct tccaggaatg ggacttgagt gaggacaaga cttcctctgc
     1501 cttgagtgct cctgttaccc cagatgtagc agtgtcccac tgccccccgc ccccccaaat
     1561 gcttaccgca gcctctaggc cctctccagc cttacacttg accccagtgg ggatggcata
     1621 ttgagccaag gtgaaccagt gaccagctct gatgacctct gtccagggac agcagcactg
     1681 agacgttgga ctcagagcag gcatatctgg ggccacagtg tactcttgcc tttctttctg
     1741 ggtggcttct aagggtggta gctgcagctg tttagaaagg cccttgggaa ttgtgaactt
     1801 aaaagagaat tgcttttagc aaaatcttga ccaaagtcag actagcccgt gagttttgag
     1861 acagcaggga tgttttctca caggaggctt ctccaccttg tttctctccg tgtctgctgt
     1921 ggaaggaggg atgggacgac caagcttcca tctctgggaa tgtgcacatt caaagacgtc
     1981 atgtggttca tctattgcgt gctataccct ggctcagccc atccatgtct gataaacgaa
     2041 tctaagcagt gcggtgaggc ccacagccca tctgccccgc ttgtgacctg aatgggggag
     2101 aaatccaagc ttaggctctg tatttgcatc gtacctgagt gtgtacatgt gtgtgttcac
     2161 atatgtgccc tcagactctg tttagcctcc tacaggaagt ataagtgagc agacatgatg
     2221 gtgcatgcct gcaatctcag catcacaggg aggcagaggc aggtggatcc ctgagttcaa
     2281 ggccatgagc ctagcctggt gttcacagtt cctggacagc cggggttaac tggtgtataa
     2341 atgatataac tgatgtc
//
