LOCUS       NM_011873               1860 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus DAZ associated protein 2 (Dazap2), mRNA.
ACCESSION   NM_011873
VERSION     NM_011873.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1860)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1860)
  AUTHORS   Ye,A., He,H. and Kim,J.
  TITLE     PEG3 binds to H19-ICR as a transcriptional repressor
  JOURNAL   Epigenetics 11 (12), 889-900 (2016)
   PUBMED   27824289
REFERENCE   3  (bases 1 to 1860)
  AUTHORS   Zepp,J.A., Wu,L., Qian,W., Ouyang,W., Aronica,M., Erzurum,S. and
            Li,X.
  TITLE     TRAF4-SMURF2-mediated DAZAP2 degradation is critical for IL-25
            signaling and allergic airway inflammation
  JOURNAL   J Immunol 194 (6), 2826-2837 (2015)
   PUBMED   25681341
  REMARK    GeneRIF: Data indicate that TNF receptor associated factor 4
            (TRAF4) recruited the E3-ligase SMURF2, to degrade the
            IL-25R-inhibitory molecule DAZ associated protein 2 (DAZAP2).
REFERENCE   4  (bases 1 to 1860)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   5  (bases 1 to 1860)
  AUTHORS   Lukas,J., Mazna,P., Valenta,T., Doubravska,L., Pospichalova,V.,
            Vojtechova,M., Fafilek,B., Ivanek,R., Plachy,J., Novak,J. and
            Korinek,V.
  TITLE     Dazap2 modulates transcription driven by the Wnt effector TCF-4
  JOURNAL   Nucleic Acids Res 37 (9), 3007-3020 (2009)
   PUBMED   19304756
REFERENCE   6  (bases 1 to 1860)
  AUTHORS   Cohen-Barak,O., Yi,Z., Hagiwara,N., Monzen,K., Komuro,I. and
            Brilliant,M.H.
  TITLE     Sox6 regulation of cardiac myocyte development
  JOURNAL   Nucleic Acids Res 31 (20), 5941-5948 (2003)
   PUBMED   14530442
  REMARK    GeneRIF: This paper reveals that the mouse DAZAP2 homolog interacts
            with Sox6 and may be involved in the regulation of a cardiac L-type
            Ca2+ channel.
REFERENCE   7  (bases 1 to 1860)
  AUTHORS   Sommerfeldt,D.W., Zhi,J., Rubin,C.T. and Hadjiargyrou,M.
  TITLE     Proline-rich transcript of the brain (prtb) is a serum-responsive
            gene in osteoblasts and upregulated during adhesion
  JOURNAL   J Cell Biochem 84 (2), 301-308 (2002)
   PUBMED   11787059
  REMARK    GeneRIF: role as an immediate early, serum-responsive, and
            adhesion-inducible gene with possible involvement in cell cycle
            control, adhesion, and proliferation
REFERENCE   8  (bases 1 to 1860)
  AUTHORS   Yang,W. and Mansour,S.L.
  TITLE     Expression and genetic analysis of prtb, a gene that encodes a
            highly conserved proline-rich protein expressed in the brain
  JOURNAL   Dev Dyn 215 (2), 108-116 (1999)
   PUBMED   10373015
REFERENCE   9  (bases 1 to 1860)
  AUTHORS   Yang,W., Musci,T.S. and Mansour,S.L.
  TITLE     Trapping genes expressed in the developing mouse inner ear
  JOURNAL   Hear Res 114 (1-2), 53-61 (1997)
   PUBMED   9447918
REFERENCE   10 (bases 1 to 1860)
  AUTHORS   Kambouris,M., Triarhou,L.C., Dlouhy,S.R., Sangameswaran,L., Luo,F.,
            Ghetti,B. and Hodes,M.E.
  TITLE     Novel cDNA clones obtained by antibody screening of a mouse
            cerebellar cDNA expression library
  JOURNAL   Brain Res Mol Brain Res 25 (3-4), 183-191 (1994)
   PUBMED   7808216
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC014808.1.
            
            On Jun 19, 2003 this sequence version replaced NM_011873.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC014808.1, BC083347.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1860
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 56.36 cM"
     gene            1..1860
                     /gene="Dazap2"
                     /gene_synonym="Brbp; Gcap28; gt6-12; mKIAA0058; Prtb"
                     /note="DAZ associated protein 2"
                     /db_xref="GeneID:23994"
                     /db_xref="MGI:MGI:1344344"
     exon            1..63
                     /gene="Dazap2"
                     /gene_synonym="Brbp; Gcap28; gt6-12; mKIAA0058; Prtb"
                     /inference="alignment:Splign:2.1.0"
     exon            64..182
                     /gene="Dazap2"
                     /gene_synonym="Brbp; Gcap28; gt6-12; mKIAA0058; Prtb"
                     /inference="alignment:Splign:2.1.0"
     exon            183..428
                     /gene="Dazap2"
                     /gene_synonym="Brbp; Gcap28; gt6-12; mKIAA0058; Prtb"
                     /inference="alignment:Splign:2.1.0"
     exon            429..1822
                     /gene="Dazap2"
                     /gene_synonym="Brbp; Gcap28; gt6-12; mKIAA0058; Prtb"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1769..1774
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dazap2"
                     /gene_synonym="Brbp; Gcap28; gt6-12; mKIAA0058; Prtb"
                     /note="hexamer: AATAAA"
     polyA_site      1817
                     /gene="Dazap2"
                     /gene_synonym="Brbp; Gcap28; gt6-12; mKIAA0058; Prtb"
                     /note="major polyA site"
ORIGIN      
        1 gagaaaaata accgtccgcg acgccgagtg ggagcggact cagagccacc atgaacagca
       61 aaggtcaata tccaacacag cctacctacc ctgtgcaacc tcctgggaat ccagtatatc
      121 ctcagacctt acatcttcct caggctccac cctatactga tgctccacct gcatattcag
      181 agctctatcg tccaagcttt gttcatccag gggctgccac agtccccacc atgtcagctg
      241 catttcctgg cgcctcattg tatctgccta tggcccagtc tgtggctgtt gggcctctag
      301 gctccacaat ccccatggct tattatccag ttggtcccat ctatccacct ggctcagcag
      361 tgttggtgga aggagggtat gatgcaggtg ccagatttgg agctggtgcc actgctggca
      421 acattcctcc tccacctcct ggatgccctc ccaacgctgc tcagctcgca gtcatgcagg
      481 gagccaacgt ccttgtaact cagcgcaagg gaaacttctt catgggtggc tcagatggtg
      541 gctacaccat ttggtgagga gccatggcca ctcctgtgcc ggggaagaca tcacatacct
      601 tcagcacttc tcacaatgta actgctttag tcatattaac ctgaagttgc agtttagaca
      661 catgtttttg gggtgtcttt ctggtgtcca aacttttgag gcacttttca aatttaataa
      721 ggaaccatgt aagggtagca gcccctccct aaagcattct gaggtaagga ggtatccatt
      781 cttcaaatga atgtgagtga agcagcccaa ggctcttcct taattcctct ggagtgatgc
      841 tgtgccatgc tggtctttgc ttctagtaat aaaacatcaa attaggtttg gagggaactt
      901 tgatcttcct aagaattaaa gttgccaaat tattctgatt ggtctttaat ctccttaagt
      961 ttttgattta tcttacttgg taaatgaaat gcattagctg tctgcctttt ccttcccatc
     1021 ctctgcccag cctgtccact gtccctgctc ctccaccccc tcccatcact atccatagaa
     1081 tcagtggtgc aggaccgaaa gccagactca gccccttgtc tccctgcacc tgtcccactt
     1141 gacatttttt aactcatctt tcataaggat cctctgaagc cccctgtgtg acctgagcac
     1201 agactccatt tcttcaggtt ttgtatatct ccaggcaagg tgaagggtac ccttcggacc
     1261 cgcctcataa accatctctg catcaccatg aacccagact agctgtggtg ccagaaacct
     1321 gaacttaaac aacagttctc agtgcaaact gtcctaggaa aatttaaaga tgacaggcag
     1381 gggagaagat gcatatcaaa agcttggctt taaagtctaa gggagtttta gatcaaaaac
     1441 tagctatcac ttcctgagtg tctcatgtag ccactcaggc tcccaggagt ttcctgaggt
     1501 aggttagtag ggtcacgtga atgcctcact atgacatgac ttgagtccag tgagatctca
     1561 ttaggattaa tatttcaggg atccttaata ttttgatttg ttttccgaga ttggatttta
     1621 ttttatctgc tatttcagtt catctaaatc ttgtgttctg tacatgtgat gtttgactgt
     1681 accatcgact gttatggaag ttcagcgttg tatgtctctc tacactgtgg tgcacttaac
     1741 ttgtggattt tttatactaa aaatgtagaa taaagactat tttgaagatt tgaataaagt
     1801 gatgaagttg cattacacct caaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
