LOCUS       NM_146057               1481 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus death-associated protein (Dap), mRNA.
ACCESSION   NM_146057
VERSION     NM_146057.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1481)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1481)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1481)
  AUTHORS   Hao,L., Vassena,R., Wu,G., Han,Z., Cheng,Y., Latham,K.E. and
            Sapienza,C.
  TITLE     The unfolded protein response contributes to preimplantation mouse
            embryo death in the DDK syndrome
  JOURNAL   Biol Reprod 80 (5), 944-953 (2009)
   PUBMED   19129515
REFERENCE   4  (bases 1 to 1481)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   5  (bases 1 to 1481)
  AUTHORS   Deiss,L.P., Feinstein,E., Berissi,H., Cohen,O. and Kimchi,A.
  TITLE     Identification of a novel serine/threonine kinase and a novel 15-kD
            protein as potential mediators of the gamma interferon-induced cell
            death
  JOURNAL   Genes Dev 9 (1), 15-30 (1995)
   PUBMED   7828849
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY272917.1, AK152884.1 and AK167579.1.
            
            On Jun 13, 2009 this sequence version replaced NM_146057.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK152216.1, AK171259.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-24                BY272917.1         2-25
            25-1477             AK152884.1         2-1454
            1478-1481           AK167579.1         1402-1405
FEATURES             Location/Qualifiers
     source          1..1481
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 12.67 cM"
     gene            1..1481
                     /gene="Dap"
                     /gene_synonym="4921531N22Rik"
                     /note="death-associated protein"
                     /db_xref="GeneID:223453"
                     /db_xref="MGI:MGI:1918190"
     exon            1..199
                     /gene="Dap"
                     /gene_synonym="4921531N22Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             145..453
                     /gene="Dap"
                     /gene_synonym="4921531N22Rik"
                     /note="DAP-1"
                     /codon_start=1
                     /product="death-associated protein 1"
                     /protein_id="NP_666169.1"
                     /db_xref="CCDS:CCDS27406.1"
                     /db_xref="GeneID:223453"
                     /db_xref="MGI:MGI:1918190"
                     /translation="MSSPPEGKLETKAGHPPAVKAGGMRIVQKHPHTGDGKEERDKDD
                     QEWESTSPPKPTVFISGVIARGDKDFPPAAAQVAHQKPHASMDKHVSPRTQHIQQPRK
                     "
     exon            200..296
                     /gene="Dap"
                     /gene_synonym="4921531N22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            297..339
                     /gene="Dap"
                     /gene_synonym="4921531N22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            340..1481
                     /gene="Dap"
                     /gene_synonym="4921531N22Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agccgtttgg agccacgccc ccctgcccgg ggcggcagtg cgcgttcccg agcagcgcgc
       61 gcctcacgcc ttcccccgag tcctcgcgcg cgcactgacg cccaccccgc ggctgccgtc
      121 gcccctccga aaaccagcgg cgccatgtct tcgcctccag aaggaaagct ggagaccaaa
      181 gctggacacc cgcccgccgt gaaagccggc gggatgcgga ttgtgcagaa acacccacat
      241 accggagatg ggaaggaaga gagagacaag gatgaccaag aatgggaaag caccagccca
      301 cctaaaccaa cagtgttcat ctctggcgtt attgctcggg gtgacaaaga cttccctcca
      361 gcggctgcac aggtggccca ccagaagcca cacgcctcca tggacaaaca cgtttctcca
      421 agaacgcagc atatccaaca gcctcgcaag tgaccggcgc ccagacccag gcacctcaga
      481 agcagcagca gcagcagcag cagcagcagc agcagcaccc acaccatctc caggatgctt
      541 ccctgacaaa aagcaactcc cgtacttccc acagagttta ctacatttag aaacctcaga
      601 caaagcaaca tgggcctcag ctctctcaga ttcccatatt gaaaactaga ggaggttcaa
      661 accccaaact ttgtttctaa gagtcctagt caagggtccc taaagggtcg ttgaaccccc
      721 cagaagtgcc attagcagaa ctcggcaagt ccttcacact gtagcagtcg ctgaaagtcc
      781 ttactcatgg tcctgagagg aagaggccac tttggagaga tttgataagg ccatatgctc
      841 caccacagct gtgctcactt ctgctcccag gccgaggctg cagagccctg cttttctgaa
      901 aagtcaaagg gctcccttag ccagacgtag agccttcccg agcgctgctc ttggcgggtg
      961 ctcctggctg tcccagtggc ctacggtggc tccagctgca gttcatgctt gctctgcagg
     1021 caccgtgtgc acctccagcc ttcatgggac tacttaccag gctgtgtcgc taaggaggga
     1081 tgggctcctc aaattttttg agcaatttag taccccagca gtggatttac aggaagcaga
     1141 acccaggcca caagtctgtg tcgtcagttt ctcccgttgt aattactgaa atggtgtgaa
     1201 gtaaccaagg gtcgctttgg agacccaggc ttggccgcaa cccacaacca aatctaggaa
     1261 gggaccttaa agccataagg ctaggtcccc ctgtgcagac cttcctacac tgtgctgtgt
     1321 acatcctgaa gcatctccaa tcccttttag ttaaacaacc tgaggggcta ccctgtgtcg
     1381 ggttctgggt cactgaaggt gactactttt tgcttgaatg aatttcctaa tctttgatgt
     1441 tgagaatatg ttgattataa taaagctcct gcatttctgc c
//
