LOCUS       NM_001114124            6540 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus disabled 2 interacting protein (Dab2ip), transcript
            variant 2, mRNA.
ACCESSION   NM_001114124
VERSION     NM_001114124.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6540)
  AUTHORS   Zhang,X., Wang,Q., Zhang,R. and Kong,Z.
  TITLE     DAB2IP-knocking down resulted in radio-resistance of breast cancer
            cells is associated with increased hypoxia and vasculogenic mimicry
            formation
  JOURNAL   Int J Radiat Biol 99 (10), 1595-1606 (2023)
   PUBMED   36947637
  REMARK    GeneRIF: DAB2IP-knocking down resulted in radio-resistance of
            breast cancer cells is associated with increased hypoxia and
            vasculogenic mimicry formation.
REFERENCE   2  (bases 1 to 6540)
  AUTHORS   Li,Q., Hua,X., Li,L., Zhou,X., Tian,Y., Deng,Y., Zhang,M., Yuan,X.
            and Chi,W.
  TITLE     AIP1 suppresses neovascularization by inhibiting the NOX4-induced
            NLRP3/NLRP6 imbalance in a murine corneal alkali burn model
  JOURNAL   Cell Commun Signal 20 (1), 59 (2022)
   PUBMED   35524333
  REMARK    GeneRIF: AIP1 suppresses neovascularization by inhibiting the
            NOX4-induced NLRP3/NLRP6 imbalance in a murine corneal alkali burn
            model.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6540)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6540)
  AUTHORS   Janani,R., Anitha,R.E., Perumal,M.K., Divya,P. and Baskaran,V.
  TITLE     Astaxanthin mediated regulation of VEGF through HIF1alpha and XBP1
            signaling pathway: An insight from ARPE-19 cell and streptozotocin
            mediated diabetic rat model
  JOURNAL   Exp Eye Res 206, 108555 (2021)
   PUBMED   33789142
  REMARK    GeneRIF: Astaxanthin mediated regulation of VEGF through HIF1alpha
            and XBP1 signaling pathway: An insight from ARPE-19 cell and
            streptozotocin mediated diabetic rat model.
REFERENCE   5  (bases 1 to 6540)
  AUTHORS   Liu,T., Lin,J., Chen,C., Nie,X., Dou,F., Chen,J., Wang,Z. and
            Gong,Z.
  TITLE     MicroRNA-146b-5p overexpression attenuates premature ovarian
            failure in mice by inhibiting the Dab2ip/Ask1/p38-Mapk pathway and
            gammaH2A.X phosphorylation
  JOURNAL   Cell Prolif 54 (1), e12954 (2021)
   PUBMED   33166004
  REMARK    GeneRIF: MicroRNA-146b-5p overexpression attenuates premature
            ovarian failure in mice by inhibiting the Dab2ip/Ask1/p38-Mapk
            pathway and gammaH2A.X phosphorylation.
REFERENCE   6  (bases 1 to 6540)
  AUTHORS   Zhang,H., He,Y., Dai,S., Xu,Z., Luo,Y., Wan,T., Luo,D., Jones,D.,
            Tang,S., Chen,H., Sessa,W.C. and Min,W.
  TITLE     AIP1 functions as an endogenous inhibitor of VEGFR2-mediated
            signaling and inflammatory angiogenesis in mice
  JOURNAL   J Clin Invest 118 (12), 3904-3916 (2008)
   PUBMED   19033661
REFERENCE   7  (bases 1 to 6540)
  AUTHORS   Luo,D., He,Y., Zhang,H., Yu,L., Chen,H., Xu,Z., Tang,S., Urano,F.
            and Min,W.
  TITLE     AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum
            stress response
  JOURNAL   J Biol Chem 283 (18), 11905-11912 (2008)
   PUBMED   18281285
  REMARK    GeneRIF: AIP1 is essential for transducing the IRE1-mediated
            endoplasmic reticulum stress response.
REFERENCE   8  (bases 1 to 6540)
  AUTHORS   Munton,R.P., Tweedie-Cullen,R., Livingstone-Zatchej,M.,
            Weinandy,F., Waidelich,M., Longo,D., Gehrig,P., Potthast,F.,
            Rutishauser,D., Gerrits,B., Panse,C., Schlapbach,R. and Mansuy,I.M.
  TITLE     Qualitative and quantitative analyses of protein phosphorylation in
            naive and stimulated mouse synaptosomal preparations
  JOURNAL   Mol Cell Proteomics 6 (2), 283-293 (2007)
   PUBMED   17114649
REFERENCE   9  (bases 1 to 6540)
  AUTHORS   Chen,H., Karam,J.A., Schultz,R., Zhang,Z., Duncan,C. and Hsieh,J.T.
  TITLE     Cloning of mouse Dab2ip gene, a novel member of the
            RasGTPase-activating protein family and characterization of its
            regulatory region in prostate
  JOURNAL   DNA Cell Biol 25 (4), 232-245 (2006)
   PUBMED   16629596
REFERENCE   10 (bases 1 to 6540)
  AUTHORS   Homayouni,R., Magdaleno,S., Keshvara,L., Rice,D.S. and Curran,T.
  TITLE     Interaction of Disabled-1 and the GTPase activating protein Dab2IP
            in mouse brain
  JOURNAL   Brain Res Mol Brain Res 115 (2), 121-129 (2003)
   PUBMED   12877983
  REMARK    GeneRIF: This study suggests that Dab2IP may function as a
            downstream effector in the Reelin signaling pathway that influences
            Ras signaling during brain development.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK147593.1, AK147464.1 and BC094373.1.
            
            On Mar 15, 2014 this sequence version replaced NM_001114124.1.
            
            Transcript Variant: This variant (2) encodes the longest isoform
            (2).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK147464.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-69                AK147593.1         2-70
            70-5644             AK147464.1         2-5576
            5645-6540           BC094373.1         3141-4036
FEATURES             Location/Qualifiers
     source          1..6540
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 23.74 cM"
     gene            1..6540
                     /gene="Dab2ip"
                     /gene_synonym="2310011D08Rik; Aip1; mKIAA1743"
                     /note="disabled 2 interacting protein"
                     /db_xref="GeneID:69601"
                     /db_xref="MGI:MGI:1916851"
     exon            1..303
                     /gene="Dab2ip"
                     /gene_synonym="2310011D08Rik; Aip1; mKIAA1743"
                     /inference="alignment:Splign:2.1.0"
     CDS             180..3749
                     /gene="Dab2ip"
                     /gene_synonym="2310011D08Rik; Aip1; mKIAA1743"
                     /note="isoform 2 is encoded by transcript variant 2;
                     disabled homolog 2-interacting protein; ASK1-interacting
                     protein 1; disabled 2 interacting protein long form;
                     DAB2-interacting protein; ASK-interacting protein 1;
                     DOC-2/DAB-2 interactive protein"
                     /codon_start=1
                     /product="disabled homolog 2-interacting protein isoform
                     2"
                     /protein_id="NP_001107596.1"
                     /db_xref="CCDS:CCDS50578.1"
                     /db_xref="GeneID:69601"
                     /db_xref="MGI:MGI:1916851"
                     /translation="MSAGGNARKSTGRPSYYYRLLRRPRLQRQRSRSRSRTRPARESP
                     QERPGSRRSLPGSMSEKNPSMEPSASTPFRVTGFLSRRLKGSIKRTKSQPKLDRNHSF
                     RHILPGFRSAAAAAADNERSHLMPRLKESRSHESLLSPSSAVEALDLSMEEEVIIKPV
                     HSSILGQDYCFEVTTSSGSKCFSCRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLW
                     VIEAKDLPAKKKYLCELCLDDVLYARTTSKLKTDNVFWGEHFEFHNLPPLRTVTVHLY
                     RETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPVVTPNPKGGKGPGPMIRIKARY
                     QTVSILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDF
                     LTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDE
                     NCEVDPSKCSSADLPEHQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRG
                     RPDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTARTLTLIAKVTQNLANFAK
                     FGSKEEYMSFMNQFLEHEWTNMQRFLLEISNPETLSNTAGFEGYIDLGRELSSLHSLL
                     WEAVSQLDQSVVSKLGPLPRILRDVHTALSTPGSGQLPGTNDLASTPGSGSSSVSAGL
                     QKMVIENDLSGLIDFTRLPSPTPENKDLFFVTRSSGVQPSPARSSSYSEANEPDLQMA
                     NGSKSLSMVDLQDARTLDGEAGSPVGPDALPADGQVPATQLLAGWPARAAPVSLAGLA
                     TVRRAVPTPTTPGTSEGAPGRPQLLAPLSFQNPVYQMAAGLPLSPRGLGDSGSEGHSS
                     LSSHSNSEELAAAAKLGSFSTAAEELARRPGELARRQMSLTEKGGQPTVPRQNSAGPQ
                     RRIDQPPPPPPPPPPAPRGRTPPTLLSTLQYPRPSSGTLASASPDWAGPGTRLRQQSS
                     SSKGDSPELKPRAMHKQGPSPVSPNALDRTAAWLLTMNAQLLEDEGLGPDPPHRDRLR
                     SKEELSQAEKDLAVLQDKLRISTKKLEEYETLFKCQEETTQKLVLEYQARLEEGEERL
                     RRQQEDKDIQMKGIISRLMSVEEELKKDHAEMQAAVDSKQKIIDAQEKRIASLDAANA
                     RLMSALTQLKERYSMQARNGVSPTNPTKLQITENGEFRNSSNC"
     exon            304..407
                     /gene="Dab2ip"
                     /gene_synonym="2310011D08Rik; Aip1; mKIAA1743"
                     /inference="alignment:Splign:2.1.0"
     exon            408..541
                     /gene="Dab2ip"
                     /gene_synonym="2310011D08Rik; Aip1; mKIAA1743"
                     /inference="alignment:Splign:2.1.0"
     exon            542..695
                     /gene="Dab2ip"
                     /gene_synonym="2310011D08Rik; Aip1; mKIAA1743"
                     /inference="alignment:Splign:2.1.0"
     exon            696..794
                     /gene="Dab2ip"
                     /gene_synonym="2310011D08Rik; Aip1; mKIAA1743"
                     /inference="alignment:Splign:2.1.0"
     exon            795..1349
                     /gene="Dab2ip"
                     /gene_synonym="2310011D08Rik; Aip1; mKIAA1743"
                     /inference="alignment:Splign:2.1.0"
     exon            1350..1494
                     /gene="Dab2ip"
                     /gene_synonym="2310011D08Rik; Aip1; mKIAA1743"
                     /inference="alignment:Splign:2.1.0"
     exon            1495..1639
                     /gene="Dab2ip"
                     /gene_synonym="2310011D08Rik; Aip1; mKIAA1743"
                     /inference="alignment:Splign:2.1.0"
     exon            1640..1876
                     /gene="Dab2ip"
                     /gene_synonym="2310011D08Rik; Aip1; mKIAA1743"
                     /inference="alignment:Splign:2.1.0"
     exon            1877..2078
                     /gene="Dab2ip"
                     /gene_synonym="2310011D08Rik; Aip1; mKIAA1743"
                     /inference="alignment:Splign:2.1.0"
     exon            2079..2257
                     /gene="Dab2ip"
                     /gene_synonym="2310011D08Rik; Aip1; mKIAA1743"
                     /inference="alignment:Splign:2.1.0"
     exon            2258..3146
                     /gene="Dab2ip"
                     /gene_synonym="2310011D08Rik; Aip1; mKIAA1743"
                     /inference="alignment:Splign:2.1.0"
     exon            3147..3299
                     /gene="Dab2ip"
                     /gene_synonym="2310011D08Rik; Aip1; mKIAA1743"
                     /inference="alignment:Splign:2.1.0"
     exon            3300..3493
                     /gene="Dab2ip"
                     /gene_synonym="2310011D08Rik; Aip1; mKIAA1743"
                     /inference="alignment:Splign:2.1.0"
     exon            3494..3581
                     /gene="Dab2ip"
                     /gene_synonym="2310011D08Rik; Aip1; mKIAA1743"
                     /inference="alignment:Splign:2.1.0"
     exon            3582..6518
                     /gene="Dab2ip"
                     /gene_synonym="2310011D08Rik; Aip1; mKIAA1743"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6493..6498
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dab2ip"
                     /gene_synonym="2310011D08Rik; Aip1; mKIAA1743"
                     /note="hexamer: ATTAAA"
     polyA_site      6518
                     /gene="Dab2ip"
                     /gene_synonym="2310011D08Rik; Aip1; mKIAA1743"
                     /note="major polyA site"
ORIGIN      
        1 ggggcggggg aggcggcgga ggaggaggag ttggagctac tttgtagggc agccttggtc
       61 ttgcctgctg ctgcaccaga gcgcgggaga gagtgcgggg cgcccgccgg gcggtccgga
      121 gcggccgatg gggcccgtgt gagcgcccag gcctggcccg gtgcccggcg ggcggcagca
      181 tgtccgccgg cggcaacgcc aggaagagca ccgggaggcc atcctactac taccggctgc
      241 tgcggcggcc ccggctgcag cgacagagga gccgctcccg cagccggacc cggccagcca
      301 gggagtcgcc ccaagaaagg ccgggctccc ggcggagcct tcccggcagc atgtcagaga
      361 aaaaccccag catggagccc tcggcttcaa ccccgttccg ggtcacgggc ttcctcagcc
      421 gccgcctcaa gggctccatc aagcgcacca agagccagcc caaactggac cgcaaccaca
      481 gcttccgcca catcctgccg gggttccgga gcgcagccgc cgccgccgcg gacaatgaga
      541 ggtcccatct gatgccaagg ctgaaggagt ctcggtcaca cgagtccctg ctcagcccca
      601 gcagcgcagt ggaggccctg gacctcagca tggaggagga ggtgattatc aagcccgttc
      661 acagcagcat cctgggtcag gactactgct tcgaggtgac aacatcatca ggaagcaagt
      721 gtttttcctg ccggtcagcc gctgagcgcg ataagtggat ggagaacctg aggcgagcag
      781 tgcaccccaa caaggacaac agccggcgtg tggagcatat cctgaagctg tgggtgattg
      841 aggccaagga tctgccggcc aagaagaagt atctatgtga actgtgcctg gacgatgtgc
      901 tgtatgcccg taccacaagc aagctcaaga cggacaatgt cttctgggga gagcactttg
      961 agttccataa cctgccgcct ctacgcacag tcactgtgca cctgtatcgg gagactgaca
     1021 agaaaaagaa aaaggaacgc aacagctacc tgggcctggt gagcctgcct gccgcctctg
     1081 tggctgggcg gcagtttgtg gagaagtggt acccagtggt gacacccaac cccaagggtg
     1141 gcaaaggccc tgggcccatg atccgaatca aggcacgcta ccagaccgtc agcatcttgc
     1201 ctatggagat gtacaaggag tttgcggagc acatcactaa ccactacctg gggctgtgcg
     1261 cagccctgga acccatcctc agtgccaaga ccaaggagga gatggcgtcg gctctggtgc
     1321 acatcctgca gagcacggga aaggtgaagg actttctaac agacctgatg atgtcagagg
     1381 tggaccgctg tggggacaat gagcacctca tcttccggga gaacacactg gccaccaagg
     1441 ccatcgagga atacctcaaa cttgtgggcc agaagtacct gcaggacgca ctaggtgagt
     1501 tcatcaaagc tctgtatgag tcagatgaaa attgtgaagt ggacccaagc aagtgctcat
     1561 ccgctgacct ccctgagcac cagggcaacc tcaagatgtg ctgtgagctg gccttctgca
     1621 agatcatcaa ctcctactgc gtcttcccac gggagcttaa ggaggtgttc gcctcatggc
     1681 ggcaggagtg tagcagccga ggccggccag atatcagtga acggctcatc agcgcctccc
     1741 tcttccttcg cttcctgtgc cctgccatca tgtcaccctc gctcttcaac ctgcttcagg
     1801 agtatcctga cgaccgcacg gctcgcaccc tcacgctcat tgccaaagtc acccagaacc
     1861 tggccaactt tgccaagttt ggcagcaagg aagaatacat gtccttcatg aaccagttcc
     1921 tggagcacga gtggaccaac atgcagcgct tcctgttgga gatctccaac cccgagaccc
     1981 tttccaacac agcaggcttc gagggctaca tagacctggg ccgggagctc tctagcctgc
     2041 actccctgct ctgggaagct gtcagccagc ttgatcagag cgttgtgtcg aagctgggac
     2101 ctctgcctcg tatcctgagg gatgtccaca cagcactgag cactcctggc agtgggcagc
     2161 tccctggcac caatgacctg gcctccaccc cgggctccgg cagcagcagc gtctctgctg
     2221 ggcttcagaa gatggtgatt gaaaatgacc tctctggtct gatagatttc acccggttac
     2281 cgtctccaac ccccgaaaac aaggacttgt tttttgtcac aaggtcctcc ggggtccagc
     2341 cttcacctgc ccgcagctca agctactcag aagccaatga acctgacctg cagatggcca
     2401 atggcagcaa gagcctgtcc atggtggacc tccaggacgc ccgcacgctg gatggggagg
     2461 caggttcccc agtgggccca gacgccctac ctgctgacgg gcaggtgcct gcgactcagc
     2521 tgctggctgg gtggccagcc agggcagccc cagtgagcct ggcaggattg gccacagtgc
     2581 ggcgggcagt gccaacacca accacaccag gcacctccga gggtgcacca ggacggcccc
     2641 agttgttggc cccactttcc ttccagaatc ctgtgtacca gatggcggcc ggcctgccac
     2701 tgtcaccccg tggccttggt gactcaggct ctgaaggcca cagctccctg agctctcaca
     2761 gcaacagtga agagctggca gccgctgcca aactaggaag tttcagcact gctgcagagg
     2821 agctggcaag gcggcctgga gaactggcac ggaggcagat gtcactgact gagaagggtg
     2881 ggcagcccac agtgccgagg caaaatagtg ccggtcccca gcggaggatt gaccagccgc
     2941 caccgccacc accaccaccg cctcctgctc cccggggcag gacacctcct accctgctga
     3001 gcaccctaca gtacccacga ccctcaagtg gaaccctggc atcagcatcc cccgactggg
     3061 ctggccctgg cacccggctg cggcaacagt cctcctcctc caagggagac agcccagagc
     3121 tgaagccccg agccatgcac aagcagggcc cttcacccgt cagtcccaat gccctggacc
     3181 gcacggccgc ttggctcttg accatgaacg cgcagttgtt agaagacgag ggtctgggcc
     3241 cagatccccc ccacagggat aggctaagga gtaaggagga actcagccaa gcagaaaagg
     3301 atctggcagt gctacaagac aagctacgga tctccaccaa gaagctggag gagtatgaga
     3361 ccctattcaa gtgccaggag gagacgacgc agaagctggt gctggagtat caggctcggc
     3421 tggaagaagg tgaggagcgg ctgcggcggc agcaggaaga caaggatatc cagatgaaag
     3481 gcatcatcag caggttgatg tcagtggaag aagaactgaa gaaggatcat gcagagatgc
     3541 aagcagctgt agattccaaa cagaagatca tcgatgccca ggaaaagcgc attgcctcgc
     3601 tggatgctgc caatgcccgc ctcatgagtg ccctcacaca gctgaaagag aggtacagca
     3661 tgcaagcccg taacggcgtc tcccccacca accccaccaa attgcagatt actgagaacg
     3721 gcgagttcag aaacagcagc aattgttaac ctgcctgagg agagggggac tgtggtggcc
     3781 cgggacaggg tctccgtcag gagactccca cagttgcagg ctagcctgca gtggaggggg
     3841 cgtaagactg atggagcgtg agactgaggg cacagtggcc ccccttctct ttgcccacct
     3901 gaacagtggg tgtgggtaga ggcagcggag actgcactgg ggagtggggc cagtctgcag
     3961 ggaggcctgc cgaatgtgtc tctggttgtt gagtttggta tgtggcacct tctctctgag
     4021 cagccaggtg catgtacccc tccttaccct ttcccatgga ggaagctacc tgcaaagggc
     4081 tcaaggaagg tttaggggcc actgctgtgg gtttcccatg gcccccagga cctgatggag
     4141 tagttgacag gcagagtggc ccctgttcat ctctgccctg agcccctgcc actgcatgca
     4201 gctggtcagg gacccttcca gggggtgagg aactgaagaa cagaacctcg gtcctatgcc
     4261 catcccagac gtgacaccct ccaccctcct tcccttcctt ccttgcattg ccaaacagac
     4321 agcactgcac tttctctgct gggccctcat acccgtggga ggagccatag cttcccacac
     4381 ttcacatgcg ggcctggctc atgctcttgg aactccagaa gccagagagc tgggcagagg
     4441 tggccaggtt gcaccatgcg ttgtagctgc cttctccagg gtcccagtgt ggcctgcaca
     4501 gtggccctgt ggggagaggc cagccagtgc tcaccctgca aaggtgatct ctcttctctg
     4561 atagtttaag aaagaattct aaagcctgcc ggccctgaga aggtggataa ctgtgatttt
     4621 ttttcctttc acagtatgca ttagaaacaa aagcccgctt gctcgcttgc tggaacacag
     4681 gggcctttta aattgagcga gcgcactgca tgggaaatag cggccctgga ggatgttaga
     4741 cttgctccct ctccaagaca gcagcagcct gcaccaggcc ccgtgtgcag tcgcctctcc
     4801 tcaccctccc agccccagcc aaggacccag gcactgcagg cagggagggg catcccccac
     4861 agctggggct ggttttcccc agctctaggc tgttctgtag catatctgtc cctccccccc
     4921 ccccctttgt gggacagaga agggcaggag cttgggtctt tcttgggtcc ccatctgttc
     4981 ccacactcta gattccaagc cctggttctg agtcacctag ggcaggagct aggctttgcc
     5041 caggcagcag aatggggcta ggcaagctgc acttaatgct cctagagtcc tcactagaaa
     5101 gcgtggacat cctgaggtgt ggcctagcta ggctgcgccc tgtcctcagt ccacgatgga
     5161 caggcaaggg taaaagaacc cagttaggct gcagaccaat gctgggagag ggcgtggcta
     5221 tcaagggtca gagacctcag gaaggaagga ggtggggctg agggcctgcc actgcctctt
     5281 cctgccccac tcctgtccac acccctgctc ccatgcattt cagcaggggt ggcctcttgg
     5341 gcagggcctg gcctggcctg gcctggcctg ggtcttgccc ttccactgcc cagggagccc
     5401 tgttttcctc ctcacccaca ctctcgccca tgcctcgtaa agtgacctct gtctgagcgc
     5461 ctcctagcaa tatggggagg tccccaggcc tggacaggag agcgcagggc cagatgcaat
     5521 ggccccctct ggtggggttg ttagctctca ggccgagagc cttatttacc tagtgcaaaa
     5581 actgtaaaag tgtacagact ctccacagat ttttatctta attgcaagtc tgcaatattt
     5641 tttttgtaaa tttttttttt gtaaatgttc ttggtgtttg actgtaatgg aactatttca
     5701 cccaagggat gtacatagtc ctttagtcct ggtgctgcga gggctggcca ggacactgct
     5761 ctcacggttg atattagagc ctggagaacg gtgctgggca ggacaaagag ctttgcagtc
     5821 taggtgtctg tctgtctgtt tcctgcccgg ggcattgatt cgttggcttt caagcatgct
     5881 gtttgggtgg aaggttgatg ggggcaaatg ccccagtggg gccagtaaag catcctcctg
     5941 cccacagcaa cggcttgggg cgtctgagct ctgcttacag caagggctgg agttgccaga
     6001 ggccctgctc tgggaagacc ctggccactg acacccaaga tctgatggag agagcggccc
     6061 cacccttgcc aacacagaca cctgaccttt ttgttcaact tgtgtgttag ggtgaaggaa
     6121 actgccaaac ttcctctgag tgaagacctc tgactgccca ggagtagggg tggggaccag
     6181 ggccagagct caacgtgtac cccagcacct gcccgaggga cactcctccc tcatactcat
     6241 aggtctggga gccagactgt ccagggaacc agcccctctt ttctatatac tcggccacaa
     6301 ggctacccga tcccccactg tgcccagctc ccccttttgt aagtatgtga aaaggaaaaa
     6361 tgcaaaggtt ggatcggccg gagcccttcc ctccagtcga gacttttaac cctgtaataa
     6421 tgtacagaga agttgttggt gttcgaagac tccgtgtggc tgtgcaattt ctgtacattt
     6481 gcaattagaa atattaaaga tttatttagc tattttaaaa aaaaaaaaaa aaaaaaaaaa
//
