LOCUS       NM_172464               5888 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus dishevelled associated activator of morphogenesis 1
            (Daam1), transcript variant 2, mRNA.
ACCESSION   NM_172464
VERSION     NM_172464.3
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5888)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5888)
  AUTHORS   Colozza,G., Lee,H., Merenda,A., Wu,S.S., Catala-Bordes,A.,
            Radaszkiewicz,T.W., Jordens,I., Lee,J.H., Bamford,A.D.,
            Farnhammer,F., Low,T.Y., Maurice,M.M., Bryja,V., Kim,J. and
            Koo,B.K.
  TITLE     Intestinal Paneth cell differentiation relies on asymmetric
            regulation of Wnt signaling by Daam1/2
  JOURNAL   Sci Adv 9 (47), eadh9673 (2023)
   PUBMED   38000028
REFERENCE   3  (bases 1 to 5888)
  AUTHORS   Santillo,A., Falvo,S., Venditti,M., Di Maio,A., Chieffi Baccari,G.,
            Errico,F., Usiello,A., Minucci,S. and Di Fiore,M.M.
  TITLE     D-Aspartate Depletion Perturbs Steroidogenesis and Spermatogenesis
            in Mice
  JOURNAL   Biomolecules 13 (4), 621 (2023)
   PUBMED   37189369
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5888)
  AUTHORS   Bellchambers,H.M. and Ware,S.M.
  TITLE     Loss of Zic3 impairs planar cell polarity leading to abnormal
            left-right signaling, heart defects and neural tube defects
  JOURNAL   Hum Mol Genet 30 (24), 2402-2415 (2021)
   PUBMED   34274973
REFERENCE   5  (bases 1 to 5888)
  AUTHORS   Rodriguez-Hernandez,I., Maiques,O., Kohlhammer,L., Cantelli,G.,
            Perdrix-Rosell,A., Monger,J., Fanshawe,B., Bridgeman,V.L.,
            Karagiannis,S.N., Penin,R.M., Marcolval,J., Marti,R.M.,
            Matias-Guiu,X., Fruhwirth,G.O., Orgaz,J.L., Malanchi,I. and
            Sanz-Moreno,V.
  TITLE     WNT11-FZD7-DAAM1 signalling supports tumour initiating abilities
            and melanoma amoeboid invasion
  JOURNAL   Nat Commun 11 (1), 5315 (2020)
   PUBMED   33082334
  REMARK    GeneRIF: WNT11-FZD7-DAAM1 signalling supports tumour initiating
            abilities and melanoma amoeboid invasion.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5888)
  AUTHORS   Ybot-Gonzalez,P., Savery,D., Gerrelli,D., Signore,M.,
            Mitchell,C.E., Faux,C.H., Greene,N.D. and Copp,A.J.
  TITLE     Convergent extension, planar-cell-polarity signalling and
            initiation of mouse neural tube closure
  JOURNAL   Development 134 (4), 789-799 (2007)
   PUBMED   17229766
REFERENCE   7  (bases 1 to 5888)
  AUTHORS   Nakaya,M.A., Habas,R., Biris,K., Dunty,W.C. Jr., Kato,Y., He,X. and
            Yamaguchi,T.P.
  TITLE     Identification and comparative expression analyses of Daam genes in
            mouse and Xenopus
  JOURNAL   Gene Expr Patterns 5 (1), 97-105 (2004)
   PUBMED   15533824
  REMARK    GeneRIF: Daams are expressed in tissues known to require Wnts, so
            effectors of Wnt signaling during vertebrate development.
REFERENCE   8  (bases 1 to 5888)
  AUTHORS   Kida,Y., Shiraishi,T. and Ogura,T.
  TITLE     Identification of chick and mouse Daam1 and Daam2 genes and their
            expression patterns in the central nervous system
  JOURNAL   Brain Res Dev Brain Res 153 (1), 143-150 (2004)
   PUBMED   15464228
  REMARK    GeneRIF: involved in pivotal steps in neuronal cell differentiation
            and movement
REFERENCE   9  (bases 1 to 5888)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   10 (bases 1 to 5888)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124356.4, BC076585.1, AK033683.1 and AK162231.1.
            
            On Nov 6, 2013 this sequence version replaced NM_172464.2.
            
            Transcript Variant: This variant (2) differs in the 5' UTR,
            compared to variant 1. Both variants 1 and 2 encode the same
            isoform (a).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC076585.1, AK129185.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10                AC124356.4         135401-135410
            11-3440             BC076585.1         1-3430
            3441-5754           AK033683.1         180-2493
            5755-5888           AK162231.1         1985-2118
FEATURES             Location/Qualifiers
     source          1..5888
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 30.06 cM"
     gene            1..5888
                     /gene="Daam1"
                     /note="dishevelled associated activator of morphogenesis
                     1"
                     /db_xref="GeneID:208846"
                     /db_xref="MGI:MGI:1914596"
     exon            1..129
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     exon            130..349
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     CDS             167..3400
                     /gene="Daam1"
                     /note="isoform a is encoded by transcript variant 2"
                     /codon_start=1
                     /product="disheveled-associated activator of morphogenesis
                     1 isoform a"
                     /protein_id="NP_766052.2"
                     /db_xref="CCDS:CCDS25964.1"
                     /db_xref="GeneID:208846"
                     /db_xref="MGI:MGI:1914596"
                     /translation="MAPRKRGGRGISFIFCCFRNNDHPEITYRLRNDSNFALQTMEPA
                     LPMPPVEELDVMFSELVDELDLTDKHREAMFALPAEKKWQIYCSKKKDQEENKGATSW
                     PEFYIDQLNSMAARKSLLALEKEEEEERSKTIESLKTALRTKPMRFVTRFIDLDGLSC
                     ILNFLKTMDYETSESRIHTSLIGCIKALMNNSQGRAHVLAHSESINVIAQSLSTENIK
                     TKVAVLEILGAVCLVPGGHKKVLQAMLHYQKYASERTRFQTLINDLDKSTGRYRDEVS
                     LKTAIMSFINAVLSQGAGVESLDFRLHLRYEFLMLGIQPVIDKLREHENSTLDRHLDF
                     FEMLRNEDELEFAKRFELVHIDTKSATQMFELTRRRLTHSEAYPHFMSILHHCLQMPY
                     KRSGNTVQYWLLLDRIIQQIVIQNDKGQDPDSTPLENFNIKNVVRMLVNENEVKQWKE
                     QAEKMRKEHNELQQKLEKKERECDAKTQEKEEMMQTLNKMKEKLEKETTEHKQVKQQV
                     ADLTAQLHELNRRAVCAAVPGGPSPGAPGGPFPSSGLGSLLPPPPPPLLSGGALPPPP
                     PPLPPGGPPPPPGPPPLGGVLPPPGAPVSLTLKKKNIPQPTNALKSFNWSKLPENKLD
                     GTVWTEIDDTKVFKILDLEDLERTFSAYQRQQEFFVNNSKQKEADAIDDTLSSKLKVK
                     ELSVIDGRRAQNCNILLSRLKLSNDEIKRAILTMDEQEDLPKDMLEQLLKFVPEKSDI
                     DLLEEHKHELDRMAKADRFLFEMSRINHYQQRLQSLYFKKKFAERVAEVKPKVEAIRS
                     GSEEVFRSRALKQLLEVVLAFGNYMNKGQRGNAYGFKISSLNKIADTKSSIDKNITLL
                     HYLITIVENKYPKVLNLSEELRDIPQAAKVNMTELDKEISTLRSGLKAVETELEYQKS
                     QPPQPGDKFVSVVSQFITLASFSFSDVEDLLAEAKELFTKAVKHFGEEAGKIQPDEFF
                     GIFDQFLQAVAEAKQENENMRKRKEEEERRARLEAQLKEQRERERKVRKAKESSEESG
                     EFDDLVSALRSGEVFDKDLSKLKRNRKRISNQVTDSSRERPITKLNF"
     exon            350..439
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     exon            440..511
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     exon            512..606
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     exon            607..940
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     exon            941..1051
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     exon            1052..1155
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     exon            1156..1222
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     exon            1223..1340
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     exon            1341..1479
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     exon            1480..1538
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     exon            1539..1726
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     exon            1727..2026
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     exon            2027..2134
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     exon            2135..2161
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     exon            2162..2268
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     exon            2269..2353
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     exon            2354..2460
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     exon            2461..2549
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     exon            2550..2718
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     exon            2719..2826
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     exon            2827..2887
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     exon            2888..3019
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     exon            3020..3190
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     exon            3191..5888
                     /gene="Daam1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3463..3468
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Daam1"
                     /note="hexamer: ATTACA"
     polyA_site      3486
                     /gene="Daam1"
     regulatory      5819..5824
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Daam1"
                     /note="hexamer: AATAAA"
     polyA_site      5839
                     /gene="Daam1"
                     /note="major polyA site"
     regulatory      5865..5870
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Daam1"
                     /note="hexamer: ATTAAA"
     polyA_site      5888
                     /gene="Daam1"
ORIGIN      
        1 tcagaggaga cgagggtgat gtcacctgcg agttggtaac ctacgagcgg ctgtgaaggg
       61 aactgtttaa ccggatccca ttgtaccggg agcgcagagc ggcctttcca gcatgcagcg
      121 gctgctcaga gtatagaaat atcaagaaat aggagagaat tcaaccatgg ccccacggaa
      181 gagaggcggc cgggggattt catttatctt ttgctgtttc cgaaacaatg accatccaga
      241 aatcacatat cggcttagga atgatagcaa ctttgcactt cagacaatgg agccggcgct
      301 gcccatgccc cctgtggagg agctcgatgt catgttcagt gaacttgtgg atgaacttga
      361 cctcacagac aaacacaggg aagccatgtt tgcacttcca gcagagaaaa agtggcagat
      421 atactgtagc aagaaaaagg accaggaaga aaacaaggga gcaaccagtt ggcccgagtt
      481 ctacattgat cagctcaatt ccatggctgc taggaaatct ctgctggctt tagagaagga
      541 agaagaggag gagaggagta aaaccatcga gagtctgaag acagcactga gaaccaagcc
      601 catgaggttt gtaaccagat tcatcgactt ggatggcctg tcatgtattc tcaactttct
      661 gaagaccatg gactatgaga cctctgagtc tcggatacac acctccctca ttggctgtat
      721 aaaggcacta atgaacaact ctcaaggccg ggcccatgtc ctggctcatt ctgagagtat
      781 caatgtaatt gctcagagtc tgagcacaga gaacattaaa acaaaggtgg ccgtgctgga
      841 aatcctgggc gctgtgtgcc tggttcctgg gggccacaag aaagttctgc aagctatgct
      901 gcactaccag aagtatgcca gcgagagaac ccgcttccag acgttaatta atgacttgga
      961 taaaagcact gggcgttatc gggatgaagt aagtctcaag acggccatca tgtccttcat
     1021 caatgcagtg ctgagccagg gagccggagt ggagagtttg gacttcaggc tccatcttcg
     1081 ctatgaattt ctgatgttag gaattcaacc tgttatagat aaattaaggg aacatgaaaa
     1141 ttcaacacta gacaggcatt tagacttttt tgaaatgctc cgaaatgaag atgaactaga
     1201 atttgccaaa agatttgaac tggttcacat agacacaaaa agcgccactc agatgtttga
     1261 gctgaccagg aggaggctaa cccacagcga agcctacccc cacttcatgt ccattctgca
     1321 ccattgcctc cagatgcctt acaagaggag tggtaacaca gttcagtact ggctgctgtt
     1381 agacagaatc atacagcaga tagttatcca gaatgacaaa gggcaggatc ccgactccac
     1441 acctctggaa aactttaata tcaagaacgt cgtaagaatg ttggttaatg aaaatgaagt
     1501 taagcaatgg aaagagcagg cagagaagat gaggaaagag cacaatgagc tacaacagaa
     1561 gctggagaag aaagagagag aatgtgatgc taagacccaa gagaaggaag aaatgatgca
     1621 gaccttaaac aagatgaaag agaagctgga aaaggagaca actgagcaca agcaagttaa
     1681 gcagcaggtg gcagacctca cggcgcagct ccacgagctg aacaggaggg ccgtctgtgc
     1741 agcagtccca ggaggaccct cacccggagc ccctggagga ccctttcctt cctctgggtt
     1801 ggggtctctt ctccctcccc caccaccccc actcctttca ggtggagcac ttcctcctcc
     1861 accacctccc ctccctcctg ggggtcctcc tcctccccca gggcctcctc ccttaggagg
     1921 agttctgcca cctcctggtg ctccagtgag tctaacactc aagaagaaga atattcccca
     1981 gcccaccaat gccctgaaat ccttcaactg gtccaagttg cctgagaaca aattggatgg
     2041 aacagtatgg actgaaattg atgataccaa agtcttcaaa attctagacc ttgaagacct
     2101 agaaagaacg ttctctgcct accaaagaca gcaggagttc tttgtgaaca actccaagca
     2161 gaaagaagca gatgccattg atgacacact gagttccaaa cttaaagtca aagagctgtc
     2221 agtgattgat ggtcggagag ctcagaattg caacatcctt ctgtcgaggt tgaaattatc
     2281 caatgatgaa atcaagcggg caattctaac aatggatgaa caggaggatc tgcccaagga
     2341 catgttagaa cagcttttga aattcgttcc tgagaaaagc gacatcgacc tgctagagga
     2401 acacaagcat gagctggatc ggatggccaa ggctgaccgc ttcctgtttg agatgagcag
     2461 aattaatcat taccagcaaa gactgcaatc actgtacttc aaaaagaagt ttgcagagcg
     2521 tgtggcagaa gtgaagccca aagtagaagc gattcgctct ggctctgagg aggtgttcag
     2581 gagccgcgcc ctcaagcagc tcctggaggt ggtcttggct tttggaaatt atatgaataa
     2641 aggacaaaga ggcaatgcat atggattcaa gatctccagc ctcaacaaga tagcggatac
     2701 caaatccagt attgacaaga acattactct tttgcactat ctaataacta ttgtggagaa
     2761 taagtacccc aaagtcctca acctaagcga agagttgcgg gatattcctc aagcagcgaa
     2821 agtaaacatg actgagctgg acaaggagat cagcaccctg aggagtggcc tgaaagctgt
     2881 agagacggag ctggagtatc agaagtctca gcccccacag cctggagaca agttcgtgtc
     2941 tgttgtcagc cagttcatca ccctggctag cttcagcttc tcagatgttg aagatcttct
     3001 agcagaagct aaagagctgt tcactaaagc agtgaagcac tttggggaag aggctggcaa
     3061 gatccagcca gatgagttct tcgggatctt tgatcagttt cttcaggccg tggccgaagc
     3121 gaaacaggaa aatgagaaca tgagaaaaag gaaggaggag gaggaacggc gggctcgcct
     3181 ggaagctcag ctcaaagagc agcgggagag ggagcggaag gtgaggaagg ccaaggagag
     3241 cagtgaagag agtggagagt ttgacgacct ggtctcggcg ctgcgctcag gagaggtgtt
     3301 cgacaaagac ctttcaaaac tcaaacggaa ccggaaacgc atttccaacc aggtgacgga
     3361 cagcagccgg gagcgaccaa tcacaaaact taatttttaa gttccttgca tccttttcta
     3421 gaaagcgccg tagcagccct tttggggtga ccagaacttt ccattacact gccttgcgat
     3481 ccaaaacaat ggcaatttct tctctcctct gtgagtgaag gtgtgaatgt gtgtgtgtaa
     3541 atgtgtgtgt atatatgtga aaatgtacat agaagtctta agtgttgtcc ggggacctat
     3601 gtgtatgctt aaaaagttca tgttaatgtg tgcacccaga aactctttgc gtatgcattc
     3661 atattgagtg ggattcattt tctttccctg aacaccgtgc ccgttcagaa gcacaatact
     3721 ttctcctaaa acagatgaca gacattcctt caaagggggt gggggggtgg agaaaagagg
     3781 aaattttaaa aaaaaaaggc ttgtcttgtg aagtatttta tggttcccaa ggttggtgta
     3841 gtgagacgat tttcactggt agaaatggag ttggaaaaca gacgggtgag ctcaacggtt
     3901 gtgggccagg caccgccacc cgcatcagtg actgacatag cggaacagct ccaaggttcc
     3961 gatgctgctg ttggggtaca cgcttgtcta gggtacaaac gtctgttgag aacatcttgc
     4021 acacattcat atcatgtaga atgtcaatca cacttcgttt atatatttaa aacttgaaca
     4081 ccgtttcccc cctaatttca tcaatttttc tgccaagtgc tcttgatgac ttctttcatt
     4141 ggttttttgg tttttttgtt ttttgaaatc acactttccc agtgatgcct cctggatcct
     4201 ggttaagaac cagaattgcc agagcttcct cattgaccta acaatacaga tctatagacc
     4261 tgacaaataa gatttcccat ccaagactta gtggaagaac tccctgaaga ttcttcttaa
     4321 aggcataggg gtgcttctgg ggcgtcttca gttttcctca caggccgtgc tgcatgtccc
     4381 aggataaagg acactcagat ggacacgaaa cgtcaacagt atctacaggg atgctcaaat
     4441 ctatttatct caaagaatat ttgaagtgat cgctgttacg tgttgtcatt ttaaattgtg
     4501 tgtcagtgac gctacctgta caatttcagt ccaaaaaata aagctctcag ggagataaaa
     4561 cacaatgagc agtagagaat aaaaatggac gcttaccact gacctgccag ctcctagtat
     4621 ccttaaatta tatggtatgt aaagaggact gttactattg ttttcttttg ctttatttat
     4681 ttgtactagg gtgtggggag ggactagcat tttctcttgt tttccatctt tccttttgtg
     4741 gttgggtttc ctgtggagag agtagttttt cctattgcac tacaatatta tttactcgct
     4801 aaattgagtt ttcttttcag tcaagtatca catatttatt aagcacttac tatgtaccag
     4861 gcatagtaga gctgtagtgg taagcaagac agagtccctg cccaccaagg agttcacatt
     4921 ctccacggtg ttttcaggga cggtagaata ccaatgtgca tagtagacag gaaccgtact
     4981 atttaaaaac taatctgtat gaactataat gtttagtgca gatggcgagg aatctgtgct
     5041 gtgtaaaagc tgtgaagcag cgctctaaga attgtcaaga gctgtgcttt ttactttttt
     5101 tttgtctttc ttcatcacaa acttagcgac cttctaccca ttatgtggaa gcaaatggct
     5161 cttcactaag gcagtcacag ggacaaagca gagctgactc tcccagcccc gcgctaacca
     5221 caggctgcaa gcatcctggc tgcggtgctg atggagacgt ggcgaggagg agtggggtgg
     5281 ggtgatggat ttcattgttc tgatctaaag tgcctctttg tatattcttt tctattgata
     5341 gcaggaaaag tttggtccag ctcagttttg gaactgtgga gagagactca caacagagag
     5401 caagtctgtg tcgcatgtcc ccttgcccct cttagaatca tcctcacatc catgtaggcc
     5461 tcccagtagg ccacctttgc catccccagc ttctgggttt attttcctaa agactgtgtg
     5521 caggaaactt catgtgccat tgttacaaac aaacaaaaat cgacttttta gactggtgct
     5581 ggtgtaagta gccacttttc tctcttgagt atgtatttta aagatttttt tttaaataat
     5641 gccaaaaatt gaaaagcatt ataattttta aacttaatta aatgtctcgt atcttattag
     5701 cttagtagct ggaaccactt agtctttagg ttgcaagact gttgttacag aaccaagaaa
     5761 aaaaaaaaga tgtgtgtgtg tgctatgaga ctgtacattt ttttaaatgg caatatgcaa
     5821 taaagatgac ttcactgggt gtacagatct gttttctatg cattattaaa atagcaaggt
     5881 taaacttc
//
