LOCUS       NM_001285882            1156 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus RIKEN cDNA D630023F18 gene (D630023F18Rik), transcript
            variant 3, mRNA.
ACCESSION   NM_001285882
VERSION     NM_001285882.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1156)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1156)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1156)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   4  (bases 1 to 1156)
  AUTHORS   Quintens,R., Verreet,T., Janssen,A., Neefs,M., Leysen,L.,
            Michaux,A., Verslegers,M., Samari,N., Pani,G., Verheyde,J.,
            Baatout,S. and Benotmane,M.A.
  TITLE     Identification of novel radiation-induced p53-dependent transcripts
            extensively regulated during mouse brain development
  JOURNAL   Biol Open 4 (3), 331-344 (2015)
   PUBMED   25681390
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1156)
  AUTHORS   Roma,G., Cobellis,G., Claudiani,P., Maione,F., Cruz,P., Tripoli,G.,
            Sardiello,M., Peluso,I. and Stupka,E.
  TITLE     A novel view of the transcriptome revealed from gene trapping in
            mouse embryonic stem cells
  JOURNAL   Genome Res 17 (7), 1051-1060 (2007)
   PUBMED   17540781
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC101869.13, AK085417.1 and AK164708.1.
            
            Transcript Variant: This variant (3) uses an alternate in-frame
            splice site in the 5' coding region and contains an alternate
            terminal exon, compared to variant 1. This results in a shorter
            protein (isoform 3) with a distinct C-terminus, compared to isoform
            1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK164708.1, CJ065752.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849385, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-21                AC101869.13        49285-49305
            22-79               AK085417.1         2-59
            80-1156             AK164708.1         1-1077
FEATURES             Location/Qualifiers
     source          1..1156
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 32.84 cM"
     gene            1..1156
                     /gene="D630023F18Rik"
                     /note="RIKEN cDNA D630023F18 gene"
                     /db_xref="GeneID:98303"
                     /db_xref="MGI:MGI:2138198"
     exon            1..162
                     /gene="D630023F18Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             122..712
                     /gene="D630023F18Rik"
                     /note="isoform 3 is encoded by transcript variant 3;
                     uncharacterized protein C2orf80 homolog"
                     /codon_start=1
                     /product="uncharacterized protein C2orf80 homolog isoform
                     3"
                     /protein_id="NP_001272811.1"
                     /db_xref="CCDS:CCDS69896.1"
                     /db_xref="GeneID:98303"
                     /db_xref="MGI:MGI:2138198"
                     /translation="MERRLVKQEVKRLLGEYIGIRLRENEFDPKGRGQLTFLDDMAHY
                     DLAISVASQWLDCSENLTWLQWEKVRAPLHVRPAYPNRKEREAMILSSYAGVLMNSIP
                     IEEVLKIYGANSSASPDSTKVAQALLPRRSLHPFAMLTAPRAAECNRRQSVKLRRGAT
                     NKNTTSSSTKKATGQNGDPVGKGTHTPATKSLRNVD"
     exon            163..244
                     /gene="D630023F18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            245..327
                     /gene="D630023F18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            328..415
                     /gene="D630023F18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            416..487
                     /gene="D630023F18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            488..575
                     /gene="D630023F18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            576..690
                     /gene="D630023F18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            691..1156
                     /gene="D630023F18Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tccctaatcc acatcccctc tgatttgctg ctgtagtttc tgggcttgca gaaactgctc
       61 ttcctaaagg ctatcggtgg atgtcaagct gcagatacct gctcagccac agccttccgt
      121 catggaaagg aggcttgtga agcaggaggt gaaaaggctg ctgggagagt atatcggaat
      181 cagacttcgg gaaaatgaat ttgatcctaa aggaagaggc caactcacct ttctagatga
      241 tatggcccac tatgacttgg ccatcagtgt tgccagtcaa tggctagatt gctcagaaaa
      301 cttaacttgg ctccagtggg agaaagtgag agcaccactt catgtcagac ctgcgtatcc
      361 aaaccgaaaa gagcgagaag caatgatctt atcatcatac gctggagtct taatgaacag
      421 tattccaatt gaagaagtcc ttaaaattta tggggccaat tcttctgcca gtcctgattc
      481 taccaaggtc gcccaggccc tgctgccccg ccgctccttg catccttttg ccatgttgac
      541 cgcacccaga gcagcagagt gcaaccggag acagagtgtc aagttgagaa gaggcgcaac
      601 gaataaaaat accaccagca gttctacaaa gaaagcaaca gggcagaatg gagatcctgt
      661 cgggaaaggc acccacaccc cagcaacaaa gtcacttaga aacgtggact agtgctgtgg
      721 acgtgtaaga gcttctagga gcagccagga tgcctcgcct taaagctaca gctgtcacca
      781 gcacccactt cttcttcagt gagctcttaa tgcaaactgc attgactatc atgtttgcca
      841 ctgagccgtc ttcttttgga agcatattgc acacctgcat tttgacaaaa aggagaaatg
      901 tgtctatcct ctgctatttc attctgtgtc tggaagacta ctggagcatc cagagggggt
      961 tcactatttc tgggtgggtc cagacaatct gactttgata cacatcttag aaaatgtgta
     1021 tcattaaata tagcatagaa ttctggagaa ggaggtggtt ttccaaaagt ttttaacccc
     1081 aaataaaacc aatttctcat tagcataact ttcagagaaa atgtaaactc attccacttc
     1141 aataaagttt gaaaag
//
