LOCUS       NM_177657               3941 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Mus musculus RIKEN cDNA D630003M21 gene (D630003M21Rik), transcript
            variant 1, mRNA.
ACCESSION   NM_177657
VERSION     NM_177657.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3941)
  AUTHORS   Skarnes,W.C., Rosen,B., West,A.P., Koutsourakis,M., Bushell,W.,
            Iyer,V., Mujica,A.O., Thomas,M., Harrow,J., Cox,T., Jackson,D.,
            Severin,J., Biggs,P., Fu,J., Nefedov,M., de Jong,P.J., Stewart,A.F.
            and Bradley,A.
  TITLE     A conditional knockout resource for the genome-wide study of mouse
            gene function
  JOURNAL   Nature 474 (7351), 337-342 (2011)
   PUBMED   21677750
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK168367.1, BC137960.1, AK052605.1 and AI465188.1.
            
            On Feb 12, 2013 this sequence version replaced NM_177657.4.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK052605.1, BC137959.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-89                AK168367.1         2-90
            90-3824             BC137960.1         1-3735
            3825-3912           AK052605.1         3824-3911
            3913-3941           AI465188.1         1-29                c
FEATURES             Location/Qualifiers
     source          1..3941
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 78.72 cM"
     gene            1..3941
                     /gene="D630003M21Rik"
                     /note="RIKEN cDNA D630003M21 gene"
                     /db_xref="GeneID:228846"
                     /db_xref="MGI:MGI:3606579"
     exon            1..141
                     /gene="D630003M21Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             139..3702
                     /gene="D630003M21Rik"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="uncharacterized protein KIAA1755 homolog isoform
                     1"
                     /protein_id="NP_808325.2"
                     /db_xref="CCDS:CCDS16986.1"
                     /db_xref="GeneID:228846"
                     /db_xref="MGI:MGI:3606579"
                     /translation="MDPSALDMAIQHALAGLYPPFEATAPTVLGQVFRLLDSDFRGDG
                     LSFLLDFLIPAKRLCEQVREAACALYTHCLFLHEGWPLCLRDEVVVHLAPLNPLLLRQ
                     GDFYLQVESWEEQSVHMTLKCLSSDLREVDKKPIPESSYSLIFTPEWLEAINNDFEGR
                     PLHNCLVASENGITPVPWTKITSPEFVDDRPPIVKVPSSDGDSCPLEDLHLSRPQEPY
                     QAGDLGGKGSVAQIWDKGKGKLSGDKYPGLIKVEPARSGQLAFRTDSEASQSLEGDYV
                     ALLGFPQEYRGASPDSEVVTLSVDIQKSQETRPRTKGAPLLGKTLPLSGPAGAPPLGR
                     WACERPAGSGEKPCSGGSRRKARHKASGHTAVRQPQQPHTSVPEKLPDCTSGLVEDTE
                     EEPAASEMQKPVGMPEAMVRLRPGPRQAFSPLLSSAGPGSPAAETKTEETTLGHGRAS
                     KPEDCLNKNASFHGSPAPGLQFSFLKEQRVPHVTPEKALLQHARPRKALCPLYSLQPC
                     EAKAPGKDGTTLPTTSGSGPLSGEPPGFRRDSAGPPGGGLRLEECSRTKPRIETLGVK
                     LLQSGIACLPGGRDKVGRPLLLVSTAEDAWEAPWCTTSEVAELLSYLCSVPRLEDKAK
                     GLLVVIDARKGTQRPGLVSALQGIQALAPASVSKVLLLGEKASIPQLSVLPAQVEVLT
                     SLKALRNHVDPSQLPEALEGPFPYHHSEWVQFFQKLDPFLTDLRQASSLLQASIQEFE
                     KGEPPGGVQEATRCLSKSKELMETVLRDPGLLALQREGGTTLASLQQEASGLNANPDV
                     RSHLTEAAALYNLVDGQLHDLVTASNQLLRRLELRVRLGHLETAIHQVSDWMAGEGSQ
                     SLQALAPVHVCAETVEKVHAEFEDFFLQVAAQYRQGLDLSKQAAQLGAAEEGAGEMGL
                     PDLAAFASTQQAFQARLTHFYMAAERQRTDLETLLHLHRFRRKMSRFHMDCQNLLTQL
                     SLGKAVKASPGDQLHLRLHCYLKRLASEFQTEKLLAMKLQVASLSRPGLGQEVWEEAQ
                     ERHQEIQSLLRKALAYCPCPEVPATQVALIDRSRPVAKGQGLPREVGSKWDRSLQDSL
                     AVDHVFKSQRTPQGEQSRNMWAGLLSPEPGQSGDTEEVRGTPKLPDPTLERLLASLFS
                     WPHLPKQSKASRPTGGSFSSEGTGSQTSLEDSPHTSPPASL"
     exon            142..339
                     /gene="D630003M21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            340..1684
                     /gene="D630003M21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1685..1867
                     /gene="D630003M21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1868..1991
                     /gene="D630003M21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1992..2085
                     /gene="D630003M21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2086..2169
                     /gene="D630003M21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2170..2286
                     /gene="D630003M21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2287..2385
                     /gene="D630003M21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2386..2534
                     /gene="D630003M21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2535..2673
                     /gene="D630003M21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2674..2796
                     /gene="D630003M21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2797..3009
                     /gene="D630003M21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3010..3915
                     /gene="D630003M21Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3894..3899
                     /regulatory_class="polyA_signal_sequence"
                     /gene="D630003M21Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3915
                     /gene="D630003M21Rik"
                     /note="major polyA site"
ORIGIN      
        1 ctgtccgggt ctggctgccc ctcgggatga ggccgggtta ggagtactcc tctcgccctt
       61 cgcactctct ccagagctag gagagccaga gcttcgcggg acagagactg ccaacgcggg
      121 gaccagagga gcatcaccat ggacccttct gcccttgaca tggccatcca gcatgccctg
      181 gcaggactct acccgccttt cgaagccact gctcccactg tcctgggtca agtgttccgg
      241 ctcctggact ccgacttccg gggagatgga ctgagcttcc tcttggattt tctcatccct
      301 gccaagcgtc tgtgtgagca agtgcgggaa gcggcttgtg ccctctatac ccactgcctc
      361 ttcctgcatg agggctggcc gttgtgtctg cgggatgaag ttgtggtaca cctggcacca
      421 ctcaatccac tcctgctacg tcagggtgat ttctaccttc aagtagagtc ctgggaggag
      481 cagtctgtcc acatgacact caagtgtctc tcttcagacc tccgtgaggt ggacaagaag
      541 ccaattcctg agtcctccta ctctctcatt ttcaccccag aatggttgga ggccatcaac
      601 aatgactttg agggacgtcc cttacacaac tgtctcgtgg cttcagaaaa tgggatcaca
      661 cctgtgcctt ggaccaagat taccagtcca gagtttgtag atgacagacc cccaatagtg
      721 aaggtccctt cctcagacgg ggactcctgt ccactagaag acctccatct gagcagaccc
      781 caggagccat accaggctgg tgacttgggc ggcaagggat ctgtggccca gatctgggat
      841 aagggtaaag ggaagttgtc tggggacaag tatccagggc tcatcaaggt ggagccagca
      901 aggtcaggtc agctcgcctt taggacagac agtgaggcca gccagagcct ggagggggac
      961 tatgtggctc tcctgggctt tccccaagag tatagagggg catccccaga cagtgaggta
     1021 gtgacattaa gtgtagatat tcaaaaatca caggagacaa gacccagaac taagggggca
     1081 cctctgcttg gaaagaccct tcctctctcg gggcctgctg gggcacctcc cttgggaaga
     1141 tgggcatgtg aaaggccagc aggctcaggg gagaagccct gtagcggagg ctcaaggaga
     1201 aaggccaggc ataaagcatc tggccacact gcagtgcgac agccacagca gccccatact
     1261 agtgtcccgg agaagctgcc ggactgtacc tctggcctgg tggaagacac tgaggaagaa
     1321 ccagcagcct ctgagatgca aaagcctgtg ggaatgccag aagccatggt tcggctcagg
     1381 cctgggccaa gacaagcatt ctctcccctc ctgtcttcag ctggccctgg atccccagcg
     1441 gctgagacaa agacagagga gaccacacta ggacatggga gagcttccaa gcctgaggac
     1501 tgcctcaata agaacgcctc cttccatggg tcccccgctc ctgggctcca gttctccttc
     1561 ttgaaagaac agagggtacc ccatgtgacc cccgagaagg ccctactcca gcatgccagg
     1621 cctcggaagg ccctgtgccc cctctactct ctgcagcctt gtgaagccaa ggccccaggc
     1681 aaagatggaa caactctccc cacaacatct ggctcaggcc cactgtctgg ggagccgcct
     1741 ggcttccgga gagattctgc aggtcctcca gggggaggac ttcgcctgga ggagtgttct
     1801 aggactaagc ccaggattga gaccctggga gtcaagcttc tccagtccgg gatagcctgc
     1861 ctgccaggtg gtagggacaa ggtggggaga ccgctgcttc tggtgtcaac cgcagaggat
     1921 gcctgggagg caccatggtg tactacctca gaggtcgcgg agttgctgtc ctacttatgc
     1981 agtgtcccta ggctggaaga taaagccaag gggctcctgg tggtgattga tgccaggaaa
     2041 gggacccaga ggcctggtct ggtcagcgcc ctgcagggca tccaggctct ggctccggcc
     2101 tccgtcagta aagtgctcct cctcggagag aaggcgtcca ttccccagct atctgtgcta
     2161 cctgcccagg tggaggtact gacgtcgctg aaggccctca gaaaccacgt ggaccctagc
     2221 cagctgccgg aggctctgga gggccccttt ccctaccacc acagcgagtg ggtgcagttc
     2281 ttccagaaac tggacccatt cctcactgac cttcgccagg cctcctccct gctgcaggct
     2341 tccatccaag agtttgagaa gggtgaaccc cctggtgggg tgcaggaggc taccaggtgc
     2401 ctgagcaagt ccaaggagct gatggagacg gtgctgaggg acccgggcct gctggctctc
     2461 cagagggaag gtggaactac tctggccagc ttgcagcaag aggccagcgg gctaaatgct
     2521 aaccccgatg tcaggagcca tctgaccgag gctgctgccc tgtacaacct tgtggatggt
     2581 cagcttcatg acttggtcac tgcgtccaat caactcctcc gaaggctgga gctccgcgtc
     2641 cgcctgggcc acctggagac tgccatccac caggtcagtg actggatggc gggagaaggc
     2701 agccagagtc tgcaggctct cgctcctgtg catgtatgtg cagagacagt agagaaagtc
     2761 cacgcagagt ttgaggattt cttcctgcag gttgcggccc agtaccgcca gggccttgac
     2821 ctgtccaagc aggcggccca gctgggagct gcagaggaag gggcaggtga gatggggctc
     2881 ccagacctgg cggccttcgc ctccacccag caggccttcc aagccaggct gacacacttc
     2941 tacatggccg ctgagaggca gcgcactgac ctggagaccc tgctccatct ccaccgtttc
     3001 agaaggaaga tgtcccggtt ccacatggac tgccagaacc tgctgaccca gctcagcctg
     3061 ggcaaggctg tgaaggccag ccctggggac cagttgcacc tccgactcca ctgctacctg
     3121 aagcgcctgg cttctgagtt ccagacggag aaactcctgg ccatgaagct ccaggtggcc
     3181 tccctgagcc ggcctggcct gggccaggag gtgtgggaag aggcccagga gcggcaccag
     3241 gagatccaga gcttgctgag gaaggcacta gcctactgcc catgcccaga ggttccagct
     3301 acccaagtgg cactcataga ccgaagcagg ccagtggcta agggtcaggg tctgcctaga
     3361 gaagtgggtt ccaaatggga caggtctcta caggactctc tggctgtgga tcatgtgttc
     3421 aaatcccagc ggacccctca aggggagcag agcagaaaca tgtgggcagg cctgctatcc
     3481 ccagaacctg gccagtctgg ggacactgag gaagtcaggg gcacccccaa gctccccgat
     3541 cccaccctgg agcggctcct tgcctccctc ttctcctggc cccaccttcc caagcagagc
     3601 aaggcctccc gtccaactgg gggaagcttt tcctcagaag ggacaggatc acagacatcc
     3661 ctggaggact caccccacac aagtcctcct gcgtccctct aactggacct gaaccaccac
     3721 accagctctg gggggctgtg acaggattga cagagggatc tgcagagccc atgccacctc
     3781 atcaaacatg gccatggtgc aatgttagga ccgccttctg gctccagaaa gctccaagac
     3841 aatggattgt tacccacact gaacagtgcg tgtgggaatt agaatccaga ctcaataaaa
     3901 ggagtttttt ttgttaaaaa aaaaaaaaaa aaaaaaaaaa a
//
