LOCUS       NM_001112699            3138 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Mus musculus cytohesin 1 (Cyth1), transcript variant 2, mRNA.
ACCESSION   NM_001112699
VERSION     NM_001112699.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3138)
  AUTHORS   Song,R., Watanabe,H., Tjen,K., Westbury,B.C., Makita,T., Tao,G. and
            Sucov,H.M.
  TITLE     A natural loss-of-function deletion of the cytohesin 1 (Cyth1) gene
            in BALB/cByJ mice does not impact cardiomyocyte polyploidy
  JOURNAL   Sci Rep 14 (1), 13333 (2024)
   PUBMED   38858421
  REMARK    GeneRIF: A natural loss-of-function deletion of the cytohesin 1
            (Cyth1) gene in BALB/cByJ mice does not impact cardiomyocyte
            polyploidy.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3138)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3138)
  AUTHORS   Han,J.S., Hino,K., Li,W., Reyes,R.V., Canales,C.P., Miltner,A.M.,
            Haddadi,Y., Sun,J., Chen,C.Y., La Torre,A. and Simo,S.
  TITLE     CRL5-dependent regulation of the small GTPases ARL4C and ARF6
            controls hippocampal morphogenesis
  JOURNAL   Proc Natl Acad Sci U S A 117 (37), 23073-23084 (2020)
   PUBMED   32873638
REFERENCE   4  (bases 1 to 3138)
  AUTHORS   Kinoshita-Kawada,M., Hasegawa,H., Hongu,T., Yanagi,S., Kanaho,Y.,
            Masai,I., Mishima,T., Chen,X., Tsuboi,Y., Rao,Y., Yuasa-Kawada,J.
            and Wu,J.Y.
  TITLE     A crucial role for Arf6 in the response of commissural axons to
            Slit
  JOURNAL   Development 146 (3) (2019)
   PUBMED   30674481
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3138)
  AUTHORS   Mohanan,V., Nakata,T., Desch,A.N., Levesque,C., Boroughs,A.,
            Guzman,G., Cao,Z., Creasey,E., Yao,J., Boucher,G., Charron,G.,
            Bhan,A.K., Schenone,M., Carr,S.A., Reinecker,H.C., Daly,M.J.,
            Rioux,J.D., Lassen,K.G. and Xavier,R.J.
  TITLE     C1orf106 is a colitis risk gene that regulates stability of
            epithelial adherens junctions
  JOURNAL   Science 359 (6380), 1161-1166 (2018)
   PUBMED   29420262
REFERENCE   6  (bases 1 to 3138)
  AUTHORS   Boehm,T., Hofer,S., Winklehner,P., Kellersch,B., Geiger,C.,
            Trockenbacher,A., Neyer,S., Fiegl,H., Ebner,S., Ivarsson,L.,
            Schneider,R., Kremmer,E., Heufler,C. and Kolanus,W.
  TITLE     Attenuation of cell adhesion in lymphocytes is regulated by CYTIP,
            a protein which mediates signal complex sequestration
  JOURNAL   EMBO J 22 (5), 1014-1024 (2003)
   PUBMED   12606567
REFERENCE   7  (bases 1 to 3138)
  AUTHORS   Goda,N., Tanoue,A., Kikuchi,S. and Tsujimoto,G.
  TITLE     Cloning and characterization of the promoter of murine cytohesin-1
            gene
  JOURNAL   Biochim Biophys Acta 1493 (1-2), 195-199 (2000)
   PUBMED   10978522
REFERENCE   8  (bases 1 to 3138)
  AUTHORS   O'Rourke,A.M., Escuro,G. and Feeney,A.J.
  TITLE     Cloning and sequencing of cDNA encoding mouse cytohesin-1
  JOURNAL   Immunogenetics 48 (5), 354-355 (1998)
   PUBMED   9745014
REFERENCE   9  (bases 1 to 3138)
  AUTHORS   Kim,H.S., Chen,Y. and Lonai,P.
  TITLE     Complex regulation of multiple cytohesin-like genes in murine
            tissues and cells
  JOURNAL   FEBS Lett 433 (3), 312-316 (1998)
   PUBMED   9744817
REFERENCE   10 (bases 1 to 3138)
  AUTHORS   Steel,M., Moss,J., Clark,K.A., Kearns,I.R., Davies,C.H.,
            Morris,R.G., Skarnes,W.C. and Lathe,R.
  TITLE     Gene-trapping to identify and analyze genes expressed in the mouse
            hippocampus
  JOURNAL   Hippocampus 8 (5), 444-457 (1998)
   PUBMED   9825957
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL591404.4, AL591109.8 and AL591204.14.
            
            On Mar 12, 2020 this sequence version replaced NM_001112699.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC057974.1, AY126516.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-120               AL591404.4         35846-35965         c
            121-203             AL591109.8         21776-21858         c
            204-268             AL591109.8         20558-20622         c
            269-335             AL591109.8         13921-13987         c
            336-454             AL591109.8         13542-13660         c
            455-535             AL591109.8         13133-13213         c
            536-648             AL591109.8         12043-12155         c
            649-797             AL591109.8         10926-11074         c
            798-909             AL591109.8         10381-10492         c
            910-986             AL591109.8         5381-5457           c
            987-1058            AL591204.14        145833-145904       c
            1059-1213           AL591204.14        144023-144177       c
            1214-3138           AL591204.14        139177-141101       c
FEATURES             Location/Qualifiers
     source          1..3138
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 82.96 cM"
     gene            1..3138
                     /gene="Cyth1"
                     /gene_synonym="CLM1; CTH-1; CYTIP; Pscd1"
                     /note="cytohesin 1"
                     /db_xref="GeneID:19157"
                     /db_xref="MGI:MGI:1334257"
     exon            1..120
                     /gene="Cyth1"
                     /gene_synonym="CLM1; CTH-1; CYTIP; Pscd1"
                     /inference="alignment:Splign:2.1.0"
     exon            121..203
                     /gene="Cyth1"
                     /gene_synonym="CLM1; CTH-1; CYTIP; Pscd1"
                     /inference="alignment:Splign:2.1.0"
     exon            204..268
                     /gene="Cyth1"
                     /gene_synonym="CLM1; CTH-1; CYTIP; Pscd1"
                     /inference="alignment:Splign:2.1.0"
     exon            269..335
                     /gene="Cyth1"
                     /gene_synonym="CLM1; CTH-1; CYTIP; Pscd1"
                     /inference="alignment:Splign:2.1.0"
     exon            336..454
                     /gene="Cyth1"
                     /gene_synonym="CLM1; CTH-1; CYTIP; Pscd1"
                     /inference="alignment:Splign:2.1.0"
     exon            455..535
                     /gene="Cyth1"
                     /gene_synonym="CLM1; CTH-1; CYTIP; Pscd1"
                     /inference="alignment:Splign:2.1.0"
     exon            536..648
                     /gene="Cyth1"
                     /gene_synonym="CLM1; CTH-1; CYTIP; Pscd1"
                     /inference="alignment:Splign:2.1.0"
     exon            649..797
                     /gene="Cyth1"
                     /gene_synonym="CLM1; CTH-1; CYTIP; Pscd1"
                     /inference="alignment:Splign:2.1.0"
     exon            798..909
                     /gene="Cyth1"
                     /gene_synonym="CLM1; CTH-1; CYTIP; Pscd1"
                     /inference="alignment:Splign:2.1.0"
     exon            910..986
                     /gene="Cyth1"
                     /gene_synonym="CLM1; CTH-1; CYTIP; Pscd1"
                     /inference="alignment:Splign:2.1.0"
     exon            987..1058
                     /gene="Cyth1"
                     /gene_synonym="CLM1; CTH-1; CYTIP; Pscd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1059..1213
                     /gene="Cyth1"
                     /gene_synonym="CLM1; CTH-1; CYTIP; Pscd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1214..3138
                     /gene="Cyth1"
                     /gene_synonym="CLM1; CTH-1; CYTIP; Pscd1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3113..3118
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cyth1"
                     /gene_synonym="CLM1; CTH-1; CYTIP; Pscd1"
                     /note="hexamer: AATAAA"
     polyA_site      3138
                     /gene="Cyth1"
                     /gene_synonym="CLM1; CTH-1; CYTIP; Pscd1"
                     /note="major polyA site"
ORIGIN      
        1 ccgcggctcg gagctggcct gtggcgagct ggtgtctggc aggacgcggg ctgcgggagg
       61 tcagtggcgg tcgcgggccg gagccggtcg ccagcaccat ggaggacgat gacagctatg
      121 tccccagtga cctgactgca gaagagcgtc aagaactgga gaacatccgg cggaggaagc
      181 aggagctgct ggctgacatc cagaggctaa aggaagagat agcagaagtt gctaatgaaa
      241 ttgaaagcct gggatccaca gaggaaagga aaaacatgca gaggaacaaa caggtagcca
      301 tgggcagaaa gaaatttaac atggatccta aaaaggggat ccagttctta atcgagaatg
      361 gcctgctgaa gaacacttgt gaggacatcg cccagttcct gtataaaggg gaggggctca
      421 acaagacagc catcggcgac taccttgggg agagggatga gttcagcatc caggtcctgc
      481 atgcgtttgt ggaactgcac gagttcaccg acctgaacct cgtccaggcc ttgcggcagt
      541 tcctgtggag cttccggctc cctggagagg cccagaagat tgaccggatg atggaggcct
      601 ttgcccagcg gtactgtcag tgcaatactg gggtgttcca gtctacagac acctgctatg
      661 tcctgtcctt cgcaatcata atgctgaaca ccagcctaca caaccccaat gtcaaagaca
      721 agcctacggt ggagagattc atcgccatga accgaggcat caacgacgga ggagacctgc
      781 cggaggagct gctccggaat ctctatgaga gcatcaaaaa cgagcccttt aaaatccccg
      841 aagatgatgg gaatgacctc acacacactt tcttcaatcc agaccgagag ggctggctgc
      901 tcaagctcgg tggcagggta aagacctgga agaggcgctg gttcattctg actgacaact
      961 gcctttacta ctttgaatac accacggaca aagagccccg cgggattatc cccctggaga
     1021 acctgagtat ccgagaagtg gaggactcca aaaagccgaa ctgctttgag ctttatatcc
     1081 ctgacaataa agaccaggtg attaaggcct gtaagacaga ggcggacggg cgagtggtgg
     1141 aagggaacca cactgtgtac cgcatctcag ccccaactcc ggaagagaag gaagactgga
     1201 tcaaatgcat caaggctgcc atcagcagag accctttcta cgagatgctt gcagcacgga
     1261 aaaagaaggt ctcctccaca aagagacact gagggggcac cagggcatgg ccagcccatg
     1321 aggctgtggc cctttctcct gcctcccctg agggcgctgt ggagccaagc agaggagagc
     1381 agagggcttc tctgccagtt cctgccgttc cgctcctaga gacttgcttc agcttttgca
     1441 gttttctaag tgggagaagg gtgggcggcg agggataggc tggagactgc ggctgccctc
     1501 atggctctgg agtcgctctc agagccagca gctgccagca gctggttcac agcctcagct
     1561 cagcagggct gaggcaccac agggagctcg ctctttacct ctcagtgttc ctggccaagg
     1621 gccttcgcct ctgctccgag aatgcctgta aggatgtact ctgtgtacta aggagagagg
     1681 gggaaaggaa gagaagccac gcactataaa gatttatttt tgtttttttt aaagcaaaag
     1741 tgaacgtagc actgtactct gccctcctgt gccctgcttc ccctaaaaag gggggccctg
     1801 gggctgcggg caccccaggg gctgcgggca ctccaggggc cgctgcctca tgactgtgtg
     1861 ggcaagacgg gcagaagcag gactgctggc agggcctagc agacacagga ggcctcaggg
     1921 ccccagcagg gcagcaggca ggcagtatgg gcagctccca cccagtgcct gggggacaga
     1981 gtgaaggtgg ttaatccctt gctggccctc agtgcccagg cccactgctc tttaaagtgg
     2041 aaagtctgca ttttcctaat aaccaaaact gtgaggagct cacccatggt gctgggtggc
     2101 gactgtttca tagctggttt ttctttctcc tccccaagag ctccactcct cgttctagag
     2161 gaaggagcag gtcttacctg atccccttgg ggcttcagcc ttttctgcct caaaagccgc
     2221 ccctattctg gactattctg gtgcactctg tggtagcctc caggagcagg ggcctttctc
     2281 agcaggttgc agtgcagtca ggcaagggta aggtggcctt tttgtcccct gccctctatg
     2341 gcatggcata ccacagcaca catgtgagtg aaccctggcc tcctaactca gtgagaaggg
     2401 agccatgaaa cgcagcatct cctgccgttc tctcagggac tctcaagggc agctcctgtt
     2461 ccttggccag ggctagcatg ccagtctagg cagagcaggt ggcaggcggt gtcttggcac
     2521 actcctccac gtggccaagg ccttggtggc agaatgctgc ctccaggcag gtggaggagc
     2581 catgggtccc cgctgggctg tgtgagctca gcctctctga tctcagaagg aggtcaacat
     2641 ctctggaaat agctttgcag agaagggtgg gtgtaggggg cggcactcgc ccctcctggg
     2701 gatacagcag gatccggcct caagaggctt caggtgcttg acactcgagt gtgaaggtga
     2761 cagtgactgc taagggtcca ggctggaaac ctgagcctcc tgccgcagaa ccagtcaatg
     2821 cctgcccagg ttgtgtgggg agtcaggcaa gtgcagagcc ctcccttcac accggttctc
     2881 acaggtgtgt cctgggcagg ccagcacctg gctcagtgtc agtctattta tcagaggtgt
     2941 aaataatcca cacatagttt ttctcctttt agattatttt gtatttgttt aaaaaatatt
     3001 tgtcaaaata caaagaaatg actgaaactt gttgacaggg tttttaaaaa tattattatt
     3061 attattattg ttttgttttt gccttgtaaa ctagctccaa ggaactgcag caaataaact
     3121 ccaaatctgc ccacatca
//
