LOCUS       NM_001368637             754 bp    mRNA    linear   ROD 11-FEB-2025
DEFINITION  Mus musculus cysteine-rich transmembrane module containing 1
            (Cystm1), transcript variant 1, mRNA.
ACCESSION   NM_001368637
VERSION     NM_001368637.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 754)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 754)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC028765.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CF550921.1, BQ945812.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-754               BC028765.1         77-830
FEATURES             Location/Qualifiers
     source          1..754
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 19.46 cM"
     gene            1..754
                     /gene="Cystm1"
                     /gene_synonym="0610010O12Rik"
                     /note="cysteine-rich transmembrane module containing 1"
                     /db_xref="GeneID:66060"
                     /db_xref="MGI:MGI:1913310"
     exon            1..44
                     /gene="Cystm1"
                     /gene_synonym="0610010O12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            45..271
                     /gene="Cystm1"
                     /gene_synonym="0610010O12Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             64..378
                     /gene="Cystm1"
                     /gene_synonym="0610010O12Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     UPF0467 protein C5orf32 homolog; cysteine-rich and
                     transmembrane domain-containing protein 1"
                     /codon_start=1
                     /product="cysteine-rich and transmembrane
                     domain-containing protein 1 isoform 1"
                     /protein_id="NP_001355566.1"
                     /db_xref="CCDS:CCDS89221.1"
                     /db_xref="GeneID:66060"
                     /db_xref="MGI:MGI:1913310"
                     /translation="MNPENPPPYPGPGPTAPYPPYPQQPMGPMGPMGAPPPQGYPYPP
                     PQGYPYQGYPQYGWQGGPQEPPKTTVYVVEDQRRDDLGPSTCLTACWTALCCCCLWDM
                     LT"
     exon            272..754
                     /gene="Cystm1"
                     /gene_synonym="0610010O12Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      734..739
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cystm1"
                     /gene_synonym="0610010O12Rik"
                     /note="hexamer: AATAAA"
     polyA_site      754
                     /gene="Cystm1"
                     /gene_synonym="0610010O12Rik"
                     /note="major polyA site"
ORIGIN      
        1 agtcgggacg gggtcagcga gcggctgctt cgtggagcag agaggtgcat caccaggttc
       61 ccgatgaacc cagagaaccc tccaccgtat ccgggccccg ggccaacagc cccataccca
      121 ccttatccac aacagccaat ggggccaatg gggcctatgg gagccccacc tcctcagggg
      181 tacccctacc caccacctca ggggtacccc tatcaaggat acccacagta cggctggcag
      241 ggtggacctc aggagcctcc taagaccaca gtgtatgtgg tggaagacca aagaagagac
      301 gacctgggcc catccacctg cctcacagcc tgctggactg ctctgtgttg ctgctgcctc
      361 tgggacatgc tcacctgatc acctgatgag cccagctctt ccgcttggcc gctctgtgcc
      421 acctccgata agtgtgcctg gccccatctc ttctgattgc tataaagtgg ctagctctgc
      481 gcagacacct ctactttctg tcctatggag ttttagatta gtgagggtta ctgctattta
      541 gttcagtgac ttgatctttt taatgttcaa aactcatttc ttactgatct ttaaaaaatg
      601 tgctaaataa tttacttttt tggccaaagg cttagttatg aaatatatat ttataatgtt
      661 taaattatac actcaaggta atggcaatat gtgacacact actagatctc tctgctcata
      721 ccctttatgt ttcaataaat ctgtccaaaa tctg
//
