LOCUS       NM_201640               2509 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus cytochrome P450, family 4, subfamily a, polypeptide 31
            (Cyp4a31), transcript variant 1, mRNA.
ACCESSION   NM_201640 XM_204174 XM_283990
VERSION     NM_201640.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2509)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2509)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   3  (bases 1 to 2509)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL626805.14.
            
            On Nov 18, 2011 this sequence version replaced NM_201640.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849385,
                              SAMN00849386 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-257               AL626805.14        26370-26626
            258-402             AL626805.14        27731-27875
            403-447             AL626805.14        28392-28436
            448-575             AL626805.14        29201-29328
            576-700             AL626805.14        32430-32554
            701-855             AL626805.14        32907-33061
            856-962             AL626805.14        33484-33590
            963-1153            AL626805.14        33679-33869
            1154-1287           AL626805.14        33966-34099
            1288-1352           AL626805.14        37421-37485
            1353-1429           AL626805.14        37611-37687
            1430-2509           AL626805.14        40657-41736
FEATURES             Location/Qualifiers
     source          1..2509
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 53.06 cM"
     gene            1..2509
                     /gene="Cyp4a31"
                     /note="cytochrome P450, family 4, subfamily a, polypeptide
                     31"
                     /db_xref="GeneID:666168"
                     /db_xref="MGI:MGI:3028580"
     exon            1..257
                     /gene="Cyp4a31"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..1598
                     /gene="Cyp4a31"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="cytochrome P450, family 4, subfamily a,
                     polypeptide 31 isoform 1"
                     /protein_id="NP_964002.2"
                     /db_xref="CCDS:CCDS51273.1"
                     /db_xref="GeneID:666168"
                     /db_xref="MGI:MGI:3028580"
                     /translation="MSVSALSLTRFAGSLSGFLQVASVFCLLLLLVKAVQVYLHRKWL
                     LKALQQFPSPPFHWFFGHEQFKGDQELQEIVSCIENFPSAFPRWFWGSKAYLTVYDPD
                     YMKVILGRSDPKANGAYRLLAPWIGYGLLLLNGQSWFQHRKMLTPAFHYDILKTYVKN
                     MADSIRLMLDKWERLAGQDSSIEIFQHISLMTLDTVMKCAFSHKGSVQVDGNYKTYLQ
                     AIGDLNNLVHSRVRNMFHQNDTIYKLSSNGRLSNQACQLAHDHTDGVIKMRKDQLQDE
                     GELENIKKKRRLDFLDILLFARMENEDSMSDKDLRAEVDTFMIEGHDTTASGVSWIFY
                     ALATHPEHQQRCREEVQSLLGDGSSITWDHLDQIPYTTMCIKEALRLYPPVPSIGREL
                     STSVTFPDGCSLPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPDSPRHSHSFLPFS
                     GGARNCIGKQFAMSELKVIVALTLLRFELLPDPTRVPMSLARFVLKSKNGIYLHLKKV
                     H"
     exon            258..402
                     /gene="Cyp4a31"
                     /inference="alignment:Splign:2.1.0"
     exon            403..447
                     /gene="Cyp4a31"
                     /inference="alignment:Splign:2.1.0"
     exon            448..575
                     /gene="Cyp4a31"
                     /inference="alignment:Splign:2.1.0"
     exon            576..700
                     /gene="Cyp4a31"
                     /inference="alignment:Splign:2.1.0"
     exon            701..855
                     /gene="Cyp4a31"
                     /inference="alignment:Splign:2.1.0"
     exon            856..962
                     /gene="Cyp4a31"
                     /inference="alignment:Splign:2.1.0"
     exon            963..1153
                     /gene="Cyp4a31"
                     /inference="alignment:Splign:2.1.0"
     exon            1154..1287
                     /gene="Cyp4a31"
                     /inference="alignment:Splign:2.1.0"
     exon            1288..1352
                     /gene="Cyp4a31"
                     /inference="alignment:Splign:2.1.0"
     exon            1353..1429
                     /gene="Cyp4a31"
                     /inference="alignment:Splign:2.1.0"
     exon            1430..2509
                     /gene="Cyp4a31"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2485..2490
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cyp4a31"
                     /note="hexamer: AATAAA"
     polyA_site      2507
                     /gene="Cyp4a31"
                     /note="major polyA site"
ORIGIN      
        1 atccttacag gatttaggca ggaggcagaa aggattattg agagtgagga cctcaacaaa
       61 ggtgaactat gagtgtctct gctctaagcc tgacccgatt tgcaggcagc ctctctggct
      121 tcctccaagt ggcctctgtg ttctgtctgc tcctgctgct ggtgaaagct gtccaggtct
      181 acctgcacag gaaatggcta ctcaaggctc tccagcagtt cccatcaccg ccctttcact
      241 ggttctttgg gcatgagcag ttcaaaggtg accaagaact acaggaaatt gtgtcatgca
      301 tagagaactt cccaagtgcc tttcctcgat ggttctgggg gagcaaggcc tacttaactg
      361 tctatgaccc tgactacatg aaagtgattc tggggcgatc agatccaaag gctaatggtg
      421 cgtacagatt gctagctcct tggattgggt atggtttgct cctgttaaac ggacagtcat
      481 ggttccagca ccggaagatg ctaaccccag ccttccacta tgacattctg aaaacctatg
      541 tgaaaaacat ggctgactcc attcgattga tgctagacaa atgggaacgg ctggctggtc
      601 aggactcctc tatagagatc tttcaacaca tctctttaat gaccctagac actgtcatga
      661 agtgtgcctt cagccacaag ggcagtgttc aggtagatgg aaattacaag acctacctcc
      721 aggccattgg ggacttgaat aacctagttc actctcgtgt gaggaatatg tttcatcaga
      781 atgatactat ctacaaactt tcttccaatg gccgcttgtc caaccaagct tgtcaacttg
      841 cccatgatca cacagatgga gtgatcaaga tgagaaagga tcagctgcag gatgagggag
      901 agctggaaaa tatcaagaag aagagacgtt tggattttct ggatatcctc ttatttgcca
      961 gaatggagaa tgaggacagc atgtctgaca aggaccttcg tgctgaggtg gacacattca
     1021 tgatcgaggg ccatgacacc acagccagtg gagtctcctg gatcttctat gctctggcca
     1081 cacaccctga gcaccaacag agatgcagag aggaagttca gagtctactg ggggatggat
     1141 cctctatcac ctgggatcac ctagaccaga ttccctatac cacaatgtgc atcaaggagg
     1201 ccctaaggct ctacccacct gtcccaagca ttggcagaga actcagtaca tctgtcacct
     1261 ttcctgatgg atgttcttta cctaaaggtg tccaggtcac actctccatt tatggtctcc
     1321 accacaaccc gaaggtgtgg ccaaacccag aggtgtttga cccttccagg tttgcaccag
     1381 actctccccg acacagccac tcattcctgc ccttctcagg aggagccagg aactgcattg
     1441 ggaaacaatt tgctatgagt gagctgaagg tgattgtggc cctgacactg ctccgcttcg
     1501 aactactgcc agatcctacc agggtcccca tgtccttagc ccgatttgtg ctgaagtcca
     1561 aaaatgggat ctacctacat ctcaagaagg tccactgatt ctgataagga caaggacaga
     1621 ctctataaac atactgcctg acatcttgtc ctgccaccat cttcctctct gtacatcttt
     1681 cttcacacct atttgttccc tgcctcctgc tctctctctc tctctctctc tctctctctc
     1741 tctctctctc tctctctctc tcacacacac acacacacac acacacacac acacaccttg
     1801 ctcctcattc cccatttgtc tttctgtctc ctgctaccta tacctgatca tgaaccttct
     1861 ccctcctcca gccatctctc cttgcctctc acttcctacc atcttatttt tccctacatg
     1921 acttcttcat tttacaaata atcaattgtc acaaccttgg tggtctgaaa taattgaaag
     1981 ttgttatctt acagttgtgg agctccatgt ctgagatgag tttcactggc agaaagctaa
     2041 gttgttggtg tgaccaacct tcttcagaag agtactccag agagtcctct catcctctgt
     2101 tcagtataga tcatcattcc ttggcactgg aatattcccc tgcttcaatg ccaccaccct
     2161 cctcgtcctg tctcttctaa tctccttccc ttttacaaat gcttatgaca tcatcaagat
     2221 ccctaaaagc tccaagatat tttcttcatc taaatatatc ttattcaatc taacctacta
     2281 agttcctttt gaattatgag gaattattca atatgtacca tgggctccaa acccaaggcc
     2341 tgaatgtcat tgtgaagcca ttattcagcc tagtatcatt ttcacatgac aattacctaa
     2401 tgtgttcatc taaatctacc ctgcatagtc tctctctacc ctattaatcc tcacacaagt
     2461 ttctccatct tccctccttt ctgcaataaa ggtccaagtg tcatgcaca
//
