LOCUS       NM_023623               1129 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus cytochrome P450, family 2, subfamily d, polypeptide 40
            (Cyp2d40), mRNA.
ACCESSION   NM_023623 XM_001001912 XM_283309 XM_894647 XM_909807 XM_921437
VERSION     NM_023623.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1129)
  AUTHORS   Ning M, Koh KH, Pan X and Jeong H.
  TITLE     Hepatocyte nuclear factor (HNF) 4alpha transactivation of
            cytochrome P450 (Cyp) 2d40 promoter is enhanced during pregnancy in
            mice
  JOURNAL   Biochem Pharmacol 94 (1), 46-52 (2015)
   PUBMED   25598084
  REMARK    GeneRIF: Cyp2d40 is induced during pregnancy through enhanced
            transactivation by HNF4alpha.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC061152.1.
            
            On or before Jan 29, 2007 this sequence version replaced
            XM_894647.2, XM_283309.4, XM_909807.2, XM_921437.2, XM_001001912.1,
            NM_023623.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC061152.1, BC087906.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849386, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1129
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 38.71 cM"
     gene            1..1129
                     /gene="Cyp2d40"
                     /gene_synonym="1300013D18Rik; CYPIID3; P450-DB3"
                     /note="cytochrome P450, family 2, subfamily d, polypeptide
                     40"
                     /db_xref="GeneID:71754"
                     /db_xref="MGI:MGI:1919004"
     exon            1..201
                     /gene="Cyp2d40"
                     /gene_synonym="1300013D18Rik; CYPIID3; P450-DB3"
                     /inference="alignment:Splign:2.1.0"
     CDS             13..1029
                     /gene="Cyp2d40"
                     /gene_synonym="1300013D18Rik; CYPIID3; P450-DB3"
                     /codon_start=1
                     /product="cytochrome P450, family 2, subfamily d,
                     polypeptide 40"
                     /protein_id="NP_076112.2"
                     /db_xref="CCDS:CCDS37162.1"
                     /db_xref="GeneID:71754"
                     /db_xref="MGI:MGI:1919004"
                     /translation="MELLTGTDLWPVAIFTVIFILLVDLLHRRQRWTSRYPPGPVPWP
                     VLGNLLQVDLDNMPYSFYKVVKMFPIVLRIPGLADKIFPGQKTFLTMVDKLVTEHKRT
                     WDPDQPPRDLTDAFMAEMETAKGNPESSFNEANLRLVVLDLFGGGIVTTSATLTWALL
                     LMILHPDVQRRVQEEIDEVIGQARRPEMADQARMPYTNAVIHEVQRFADIAPMTLPHR
                     TSCDIEVQGFLIPKGTTLICNLSSVLKDETVWEKPLRFYPEHFLDAQGHFVKPEAFMP
                     FSAGRRACLGEPLVRMELFLFFTCLLQRFSFSVPDGQPLPSDYGIYSMVVSPAPYQLC
                     AVVR"
     exon            202..378
                     /gene="Cyp2d40"
                     /gene_synonym="1300013D18Rik; CYPIID3; P450-DB3"
                     /inference="alignment:Splign:2.1.0"
     exon            379..520
                     /gene="Cyp2d40"
                     /gene_synonym="1300013D18Rik; CYPIID3; P450-DB3"
                     /inference="alignment:Splign:2.1.0"
     exon            521..708
                     /gene="Cyp2d40"
                     /gene_synonym="1300013D18Rik; CYPIID3; P450-DB3"
                     /inference="alignment:Splign:2.1.0"
     exon            709..850
                     /gene="Cyp2d40"
                     /gene_synonym="1300013D18Rik; CYPIID3; P450-DB3"
                     /inference="alignment:Splign:2.1.0"
     exon            851..1102
                     /gene="Cyp2d40"
                     /gene_synonym="1300013D18Rik; CYPIID3; P450-DB3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtggggcag ccatggagct gctgactggg actgacctgt ggcctgtggc catattcaca
       61 gtcatcttca tattactggt ggacctgttg caccggcgcc agcgctggac ttctcgctac
      121 ccaccgggcc ctgtgccatg gcctgtgctg ggtaacctgc tgcaggtgga cctggataac
      181 atgccataca gcttttacaa ggttgtgaag atgttcccaa ttgtcctgcg catcccaggg
      241 ttggctgata aaatcttccc tgggcaaaag acatttctca ccatggtgga taagctggtg
      301 actgagcaca agaggacctg ggaccctgac cagccacctc gtgacctgac tgatgccttt
      361 atggctgaga tggagacggc aaaggggaac cctgagagta gcttcaatga agcaaatcta
      421 cgtctggttg tccttgacct gtttggtggt gggattgtga ccacttcagc tactctgacc
      481 tgggccctgc tactcatgat tctgcatcca gatgtgcagc gccgagtgca agaggaaatc
      541 gacgaggtca tagggcaggc acggcgtcca gagatggcag accaggcccg catgccctac
      601 accaatgctg tcattcatga ggtgcagcgc tttgctgaca tcgccccaat gactttgcca
      661 cacaggactt cttgtgacat tgaagtgcag ggcttcctta tccctaaggg gacaaccctc
      721 atctgcaacc tgtcctccgt gctgaaggat gagactgtct gggagaagcc cctccgcttc
      781 tatcctgaac acttcctgga tgcccagggc cactttgtga agcctgaggc cttcatgcca
      841 ttctcagcag gccgtcgagc atgtctgggt gagcccctgg tccgcatgga gctcttcctc
      901 ttcttcacct gcctcctgca gcgctttagc ttctcagtac cggatggaca gccccttccc
      961 agtgattatg gcatctactc aatggtagtt agtccagcac cctaccagct ctgtgcagtg
     1021 gttcgctaga agggtcagtg gttccagtct tctccccagt ttgggcttat tgatgtccaa
     1081 taaacaagtt ctgtgtctgc aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
//
