LOCUS       NM_201360               1633 bp    mRNA    linear   ROD 10-OCT-2020
DEFINITION  Mus musculus cytochrome P450, family 2, subfamily d, polypeptide 12
            (Cyp2d12), transcript variant 1, mRNA.
ACCESSION   NM_201360 XM_354908
VERSION     NM_201360.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1633)
  AUTHORS   Nelson DR, Kamataki T, Waxman DJ, Guengerich FP, Estabrook RW,
            Feyereisen R, Gonzalez FJ, Coon MJ, Gunsalus IC, Gotoh O et al.
  TITLE     The P450 superfamily: update on new sequences, gene mapping,
            accession numbers, early trivial names of enzymes, and nomenclature
  JOURNAL   DNA Cell Biol 12 (1), 1-51 (1993)
   PUBMED   7678494
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC132878.13.
            
            On Sep 23, 2017 this sequence version replaced NM_201360.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK078880.1, BC139170.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849385, SAMN00849389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-247               AC132878.13        123823-124069
            248-419             AC132878.13        124935-125106
            420-572             AC132878.13        125378-125530
            573-733             AC132878.13        125610-125770
            734-910             AC132878.13        126392-126568
            911-1052            AC132878.13        126752-126893
            1053-1240           AC132878.13        127086-127273
            1241-1382           AC132878.13        127655-127796
            1383-1633           AC132878.13        127897-128147
FEATURES             Location/Qualifiers
     source          1..1633
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 38.64 cM"
     gene            1..1633
                     /gene="Cyp2d12"
                     /gene_synonym="9030605E09Rik"
                     /note="cytochrome P450, family 2, subfamily d, polypeptide
                     12"
                     /db_xref="GeneID:380997"
                     /db_xref="MGI:MGI:88604"
     exon            1..247
                     /gene="Cyp2d12"
                     /gene_synonym="9030605E09Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             59..1573
                     /gene="Cyp2d12"
                     /gene_synonym="9030605E09Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     cytochrome P450, 2d12"
                     /codon_start=1
                     /product="cytochrome P450, family 2, subfamily d,
                     polypeptide 12 isoform 1"
                     /protein_id="NP_958748.1"
                     /db_xref="CCDS:CCDS37160.1"
                     /db_xref="GeneID:380997"
                     /db_xref="MGI:MGI:88604"
                     /translation="MELLTGTDLWSVAIFTVIFILLVDLMHRRQSWTSCYPPGPVPWP
                     VLGNLLQVDLNNMPYSLYKLQNRYGDVFSLQMAWKPMVVINRMKAMKEVLLTCGEDTA
                     DRPPVPIFEHLGFKPRSQGMIFAPYGPEWREQRRFSLSSLRNFGLGRKSLEEWVIKEA
                     GHLCDAFTTQAGQYINPNTMLKKATCNVIASLIFARRFEYEDPYLIRMLKVLEDSLTE
                     LSGLIPEVINTFPILLHIPRLADKFLQSQKSFIAIVDNLLTENRTTWDPAQSPRNLTD
                     AFLAEIEKAKGNPESSFNDENLRMVVIDLFTAGILTTSTTLSWALLLMILHPDVQRRV
                     QQEIDEVIGQVRHPEMADQAHMPYTNAVIHEVQRFGDIVPLHLPRITSRDIEVQDFLI
                     PKGTILLPNMSSVHMDDTVWEKPLRFHPEHFLDAQGHFVKHEAFITFSAGRRSCLGEP
                     LARMELFLFFTCLLQRFSFSVPDGQPQPSDHRVFSIMVAPSPYQLCAVIREQGH"
     exon            248..419
                     /gene="Cyp2d12"
                     /gene_synonym="9030605E09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            420..572
                     /gene="Cyp2d12"
                     /gene_synonym="9030605E09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            573..733
                     /gene="Cyp2d12"
                     /gene_synonym="9030605E09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            734..910
                     /gene="Cyp2d12"
                     /gene_synonym="9030605E09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            911..1052
                     /gene="Cyp2d12"
                     /gene_synonym="9030605E09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1053..1240
                     /gene="Cyp2d12"
                     /gene_synonym="9030605E09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1241..1382
                     /gene="Cyp2d12"
                     /gene_synonym="9030605E09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1383..1633
                     /gene="Cyp2d12"
                     /gene_synonym="9030605E09Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgtttgatgt agcgtttttc attggtctct gggaagcctg ggaagcagtg gggcagtcat
       61 ggagctgctg actgggactg acctgtggtc tgtggccata ttcacagtca tcttcatatt
      121 actggtggac ctgatgcacc ggcgccagag ctggacttct tgctacccac caggccctgt
      181 gccatggcct gtgctgggta acctgctgca ggtagaccta aataatatgc catacagctt
      241 gtacaagctt caaaaccgct atggtgacgt gtttagccta cagatggcct ggaagcctat
      301 ggttgtgatc aacagaatga aggcaatgaa ggaagtgctg ttgacctgtg gagaggacac
      361 tgctgaccgc cctccagtgc ccatctttga gcatcttggt ttcaagccca gatcccaagg
      421 tatgatcttt gcaccctatg gacctgagtg gcgagagcag aggcgattct ctttgtcttc
      481 tctgcgcaat tttggcctgg gcaggaaatc tctggaggag tgggtgatca aggaggccgg
      541 ccacctctgt gatgccttca ctactcaggc tgggcagtac atcaatccca acaccatgct
      601 gaaaaaagct acgtgcaatg tgattgcatc tctcattttt gcccgtcgct ttgaatatga
      661 agacccttac ctcatcagga tgctgaaagt actggaagat agtttgacag aactctctgg
      721 attaattcct gaggttatta acacattccc gatactcctg cacatcccaa ggctggctga
      781 caagttcctg caaagtcaga agtccttcat cgccatagtg gataacctgt tgactgaaaa
      841 caggaccact tgggaccctg cccagtcacc ccgaaatttg actgatgcct tcctggcaga
      901 gatagagaag gccaagggaa atcctgagag cagcttcaat gatgagaacc tgcgcatggt
      961 ggtaatagac ctgttcactg cagggattct gaccacctca accacactgt cctgggccct
     1021 gctgctcatg atcctgcatc cagatgtgca gcgcagagtc caacaagaaa tcgatgaggt
     1081 catagggcag gtgaggcatc cagagatggc agaccaggcc cacatgccct acaccaatgc
     1141 tgtcattcat gaggtgcagc gctttgggga cattgttcca ctgcatttgc cacgcatcac
     1201 aagtcgtgac attgaagtgc aggacttcct catccccaag gggacgatcc tcctccccaa
     1261 catgtcctct gtgcatatgg atgacactgt ctgggagaag cccctccgct tccatcctga
     1321 acacttcctg gatgcccagg gccactttgt gaagcatgag gcctttataa cattttcagc
     1381 aggccgcaga tcatgcctgg gggagcccct ggcccgaatg gagctcttcc tcttcttcac
     1441 ctgcctcctg cagcgcttta gcttctcagt gcctgatgga cagccccagc ccagtgacca
     1501 tagagtcttt tctattatgg ttgccccctc cccctaccag ctctgtgctg tgatacgtga
     1561 gcaaggacac taattccata caggctctgc agggaaggct gtgtcatgta gaataaacta
     1621 gtcttgtggt tgc
//
