LOCUS       NM_001104531            1590 bp    mRNA    linear   ROD 16-FEB-2024
DEFINITION  Mus musculus cytochrome P450, family 2, subfamily d, polypeptide 11
            (Cyp2d11), mRNA.
ACCESSION   NM_001104531 XM_001479925
VERSION     NM_001104531.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1590)
  AUTHORS   Wong,G., Itakura,T., Kawajiri,K., Skow,L. and Negishi,M.
  TITLE     Gene family of male-specific testosterone 16 alpha-hydroxylase
            (C-P-450(16 alpha)) in mice. Organization, differential regulation,
            and chromosome localization
  JOURNAL   J Biol Chem 264 (5), 2920-2927 (1989)
   PUBMED   2914938
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC113593.14.
            
            On Sep 13, 2007 this sequence version replaced XM_001479925.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN01164135,
                              SAMN01164143 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-264               AC113593.14        89309-89572         c
            265-436             AC113593.14        87926-88097         c
            437-589             AC113593.14        87505-87657         c
            590-750             AC113593.14        87254-87414         c
            751-927             AC113593.14        86443-86619         c
            928-1069            AC113593.14        85931-86072         c
            1070-1257           AC113593.14        85547-85734         c
            1258-1399           AC113593.14        85002-85143         c
            1400-1590           AC113593.14        84704-84894         c
FEATURES             Location/Qualifiers
     source          1..1590
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 38.58 cM"
     gene            1..1590
                     /gene="Cyp2d11"
                     /gene_synonym="Cyp2d; P450-2D"
                     /note="cytochrome P450, family 2, subfamily d, polypeptide
                     11"
                     /db_xref="GeneID:545123"
                     /db_xref="MGI:MGI:88603"
     exon            1..264
                     /gene="Cyp2d11"
                     /gene_synonym="Cyp2d; P450-2D"
                     /inference="alignment:Splign:2.1.0"
     CDS             76..1590
                     /gene="Cyp2d11"
                     /gene_synonym="Cyp2d; P450-2D"
                     /EC_number="1.14.14.1"
                     /note="CYPIID11; cytochrome P450CC; cytochrome
                     P450-16-alpha; testosterone 16-alpha hydroxylase;
                     cytochrome P450, 2d11"
                     /codon_start=1
                     /product="cytochrome P450 2D11"
                     /protein_id="NP_001098001.1"
                     /db_xref="CCDS:CCDS49680.1"
                     /db_xref="GeneID:545123"
                     /db_xref="MGI:MGI:88603"
                     /translation="MELLTGAGLWSVAIFTVIFILLVDLMHRHQHWTSRCPPGPVPWP
                     VLGNLLQVDLGNMPYSLYKLQNRYGDVFSLQMGWKPMVVINGLKAMKEVLLTCGEDTA
                     DRPQVPIFEYLGVKPGSQGVVLAPYGPEWQEQRRFSVSTLRNFGLGKKSLEDWVTKEA
                     RHLCDAFTAQAGQSINPNTMLNNAVCNVIASLIFARRFEYEDPYLIRMLKMLKECFTE
                     ISGFIPGVLNEFPIFLRIPGLADMVFQGQKSFMAILDNLLTENRTTWDPDQPPRNLTD
                     AFLAEIEKAKGNPESSFNDENLRMVVGDLFTAGMVTTSTTLSWALLLMILHPDVQRRV
                     QQEIDAVIGQVQHPEMADQARMPYTNAVIHEVQRFGDIAPLPLPRITSRDIEVQDFLV
                     TKGSTLIPNMSSVLKDETVWEKPLRFHPEHFLDAQGHFVKPEAFMPFSAGHRSCLGEA
                     LARMELFLFFTCLLQRFSISVPDGQPQPSNYRVHAIPVAPFPYQLCAVMREQGH"
     exon            265..436
                     /gene="Cyp2d11"
                     /gene_synonym="Cyp2d; P450-2D"
                     /inference="alignment:Splign:2.1.0"
     exon            437..589
                     /gene="Cyp2d11"
                     /gene_synonym="Cyp2d; P450-2D"
                     /inference="alignment:Splign:2.1.0"
     exon            590..750
                     /gene="Cyp2d11"
                     /gene_synonym="Cyp2d; P450-2D"
                     /inference="alignment:Splign:2.1.0"
     exon            751..927
                     /gene="Cyp2d11"
                     /gene_synonym="Cyp2d; P450-2D"
                     /inference="alignment:Splign:2.1.0"
     exon            928..1069
                     /gene="Cyp2d11"
                     /gene_synonym="Cyp2d; P450-2D"
                     /inference="alignment:Splign:2.1.0"
     exon            1070..1257
                     /gene="Cyp2d11"
                     /gene_synonym="Cyp2d; P450-2D"
                     /inference="alignment:Splign:2.1.0"
     exon            1258..1399
                     /gene="Cyp2d11"
                     /gene_synonym="Cyp2d; P450-2D"
                     /inference="alignment:Splign:2.1.0"
     exon            1400..1590
                     /gene="Cyp2d11"
                     /gene_synonym="Cyp2d; P450-2D"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcttcctga tcctaggtgt tgtattgagt gttggtcatt ggcctctggg aagcctgggc
       61 agcagtgggg caaccatgga gctgctgact ggggctggcc tgtggtctgt ggccatattc
      121 accgtcatct tcatattact ggtggacctg atgcaccggc accagcactg gacttctcgc
      181 tgcccaccag gccctgtgcc atggcctgta ctgggtaact tgctgcaggt ggacctaggt
      241 aacatgccat acagcttgta caagcttcaa aaccgctatg gtgacgtgtt cagcctgcag
      301 atgggctgga agcctatggt tgtgatcaat ggactgaagg caatgaagga agtgctgttg
      361 acctgtggag aggacactgc tgaccgccct caagtgccca tctttgagta cctgggtgtg
      421 aagcctggat cccaaggtgt ggtccttgca ccctacgggc ccgagtggca agagcagagg
      481 cgattctctg tgtctaccct gcgcaacttc ggcctgggca agaaatcact ggaggactgg
      541 gtgaccaagg aggccagaca cctctgtgat gccttcaccg cccaggctgg gcagtccatc
      601 aatcccaaca ccatgctgaa caacgctgtg tgcaatgtga ttgcatctct catttttgcc
      661 cgtcgctttg aatatgaaga cccttacctc atcaggatgc taaaaatgct gaaagaatgt
      721 ttcacagaaa tctctggctt cattcctggg gtacttaatg agttcccaat attcctgcgc
      781 atcccagggc tggctgacat ggtcttccaa ggtcagaagt ccttcatggc catactggat
      841 aacctgttga ctgagaatag gaccacctgg gaccctgacc agccaccccg aaatttgact
      901 gatgccttcc tggcagagat agaaaaggcc aaggggaatc ctgagagcag cttcaatgat
      961 gagaacctgc gcatggtggt gggtgacctg ttcactgcag ggatggtgac cacctcaacc
     1021 acactgtcct gggccctgct gctcatgatc ctgcatccgg atgtgcagcg cagagtccaa
     1081 caggaaatcg atgcggtcat agggcaagtg cagcatccag agatggcaga ccaggctcgc
     1141 atgccctaca ccaatgctgt cattcatgag gtgcagcgct ttggggacat tgctccactg
     1201 cctttgccac gcatcacaag tcgtgacatt gaagtgcaag acttcctcgt caccaagggg
     1261 tcgaccctca tccccaacat gtcctccgtg ctgaaagatg agactgtctg ggaaaagccc
     1321 ctccgcttcc atcctgaaca cttcctcgat gcccagggcc actttgtgaa gcctgaggcc
     1381 ttcatgccat tctcagcagg acacagatca tgcctggggg aggccctggc ccgcatggag
     1441 ctcttcctct tcttcacctg cctcctgcag cgctttagca tctcagtgcc tgatggacag
     1501 ccccagccca gcaactatag agtccatgct attccagttg cccccttccc ctaccagctc
     1561 tgtgctgtga tgcgtgagca aggacactaa
//
