LOCUS       NM_010005               1681 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus cytochrome P450, family 2, subfamily d, polypeptide 10
            (Cyp2d10), mRNA.
ACCESSION   NM_010005
VERSION     NM_010005.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1681)
  AUTHORS   Creasy,K.T., Jiang,J., Ren,H., Peterson,M.L. and Spear,B.T.
  TITLE     Zinc Fingers and Homeoboxes 2 (Zhx2) Regulates Sexually Dimorphic
            Cyp Gene Expression in the Adult Mouse Liver
  JOURNAL   Gene Expr 17 (1), 7-17 (2016)
   PUBMED   27197076
REFERENCE   2  (bases 1 to 1681)
  AUTHORS   Ichikawa,T., Itakura,T. and Negishi,M.
  TITLE     Functional characterization of two cytochrome P-450s within the
            mouse, male-specific steroid 16 alpha-hydroxylase gene family:
            expression in mammalian cells and chimeric proteins
  JOURNAL   Biochemistry 28 (11), 4779-4784 (1989)
   PUBMED   2788458
REFERENCE   3  (bases 1 to 1681)
  AUTHORS   Wong,G., Itakura,T., Kawajiri,K., Skow,L. and Negishi,M.
  TITLE     Gene family of male-specific testosterone 16 alpha-hydroxylase
            (C-P-450(16 alpha)) in mice. Organization, differential regulation,
            and chromosome localization
  JOURNAL   J Biol Chem 264 (5), 2920-2927 (1989)
   PUBMED   2914938
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CA457792.1, BF660186.1, CB951489.1, AI323751.1 and AA239803.1.
            
            On Apr 25, 2009 this sequence version replaced NM_010005.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC010989.1, BC057924.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849386, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-564               CA457792.1         37-600
            565-1103            BF660186.1         1-539
            1104-1370           CB951489.1         333-599
            1371-1645           AI323751.1         2-276               c
            1646-1681           AA239803.1         341-376
FEATURES             Location/Qualifiers
     source          1..1681
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 38.58 cM"
     gene            1..1681
                     /gene="Cyp2d10"
                     /gene_synonym="Cyp2d; P450-2D"
                     /note="cytochrome P450, family 2, subfamily d, polypeptide
                     10"
                     /db_xref="GeneID:13101"
                     /db_xref="MGI:MGI:88602"
     exon            1..261
                     /gene="Cyp2d10"
                     /gene_synonym="Cyp2d; P450-2D"
                     /inference="alignment:Splign:2.1.0"
     exon            262..433
                     /gene="Cyp2d10"
                     /gene_synonym="Cyp2d; P450-2D"
                     /inference="alignment:Splign:2.1.0"
     exon            434..586
                     /gene="Cyp2d10"
                     /gene_synonym="Cyp2d; P450-2D"
                     /inference="alignment:Splign:2.1.0"
     exon            587..747
                     /gene="Cyp2d10"
                     /gene_synonym="Cyp2d; P450-2D"
                     /inference="alignment:Splign:2.1.0"
     exon            748..924
                     /gene="Cyp2d10"
                     /gene_synonym="Cyp2d; P450-2D"
                     /inference="alignment:Splign:2.1.0"
     exon            925..1066
                     /gene="Cyp2d10"
                     /gene_synonym="Cyp2d; P450-2D"
                     /inference="alignment:Splign:2.1.0"
     exon            1067..1254
                     /gene="Cyp2d10"
                     /gene_synonym="Cyp2d; P450-2D"
                     /inference="alignment:Splign:2.1.0"
     exon            1255..1396
                     /gene="Cyp2d10"
                     /gene_synonym="Cyp2d; P450-2D"
                     /inference="alignment:Splign:2.1.0"
     exon            1397..1647
                     /gene="Cyp2d10"
                     /gene_synonym="Cyp2d; P450-2D"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1626..1631
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cyp2d10"
                     /gene_synonym="Cyp2d; P450-2D"
                     /note="hexamer: AATAAA"
     polyA_site      1647
                     /gene="Cyp2d10"
                     /gene_synonym="Cyp2d; P450-2D"
                     /note="major polyA site"
ORIGIN      
        1 agtctgattc taggtgttac attgagtgtt gttcattggt ctctggaaag cctgggcaga
       61 agtggggtag ccatggagct gctgactggg gctggcctgt ggtctgtggc catattcacc
      121 gttatcttca tattactggt ggacctgatg caccggcacc agcgctggac ttctcgctac
      181 ccaccgggcc ctgtgccatg gcctgtgctg ggtaacctgc tgcaggtgga cctggataac
      241 atgccataca gcttgtacaa gcttcaaaac cgctatggtg acgtgttcag cctgcagatg
      301 ggctggaagc ctatggttgt gatcaatgga ctgaaggcaa tgaaggaagt gctgttgacc
      361 tgtggagagg acactgctga ccgccctcaa gtgcccatct ttgagtacct gggtgtgaag
      421 cctggatccc aaggtgtggt ccttgcaccc tacgggcccg agtggcgaga gcagaggcga
      481 ttctctgtgt ctaccctgcg caactttggc ctgggcaaga aatcactgga ggactgggtg
      541 accaaggagg ccagacacct ctgtgatgcc ttcaccgccc aggctgggca gcccatcaat
      601 cccaacacca tgctgaacaa cgctgtgtgc aatgtgattg catctctcat ttttgcccgt
      661 cgctttgaat atgaagaccc ttacctcatc aggatgcaga aagtactgga agatagtttg
      721 acagaaatct ctggcttaat tcctgaggtt cttaatatgt tccccatact cctgcgcatc
      781 ccaggactgc ctgggaaggt cttccaaggt cagaagtcct tactggccat agtggagaat
      841 ctgttgactg agaataggaa cacctgggac cctgaccagc caccccgaaa tttgactgat
      901 gccttcctgg cagagataga gaaggtaaag gggaatgctg agagcagctt caatgatgag
      961 aacctgcgca tggttgtgct agacctgttc actgcaggga tggtgaccac ctcaaccaca
     1021 ctgtcctggg ccctgctgct catgatcctg catccggatg tgcagcgcag agtccaacag
     1081 gaaatcgatg cggtcatagg gcaggtgcgg catccagaga tggcagacca ggctcgtatg
     1141 ccctacacca atgctgtcat tcatgaggta cagcgctttg gggacattgc tccactgaat
     1201 ttgccacgca tcacaagtcg tgacattgaa gtgcaggact tcctcatccc caaggggtca
     1261 atcctcatcc ccaacatgtc ctccgtgctg aaggatgaga ctgtctggga aaagcccctc
     1321 cgcttccatc ctgaacactt cctcgatgcc cagggccact ttgtgaagcc tgaggccttc
     1381 atgccattct cagcaggccg cagatcatgc ctgggtgagc ccctggcccg catggagctc
     1441 ttcctcttct tcacgtgcct cctgcagcac tttagcttct cagtgcccaa tggacagccc
     1501 aggcctagaa accttggtgt ctttcctttt ccggttgccc cctaccccta ccagctctgt
     1561 gctgtgatgc gtgagcaagg acactaattc cagtcatggt aggcagggca ggctgagcca
     1621 tgcaaaataa accaatcttg tggctgcaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1681 a
//
