LOCUS       NM_028191               1941 bp    mRNA    linear   ROD 07-AUG-2023
DEFINITION  Mus musculus cytochrome P450, family 2, subfamily c, polypeptide 65
            (Cyp2c65), mRNA.
ACCESSION   NM_028191 XM_129243
VERSION     NM_028191.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1941)
  AUTHORS   Chen S, Lu W, Yueh MF, Rettenmeier E, Liu M, Paszek M, Auwerx J, Yu
            RT, Evans RM, Wang K, Karin M and Tukey RH.
  TITLE     Intestinal NCoR1, a regulator of epithelial cell maturation,
            controls neonatal hyperbilirubinemia
  JOURNAL   Proc Natl Acad Sci U S A 114 (8), E1432-E1440 (2017)
   PUBMED   28167773
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2017 May 16;114(20):E4115.
            Paszek, Miles [added]. PMID: 28484028]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC100729.21 and AK008688.1.
            
            On Nov 18, 2009 this sequence version replaced NM_028191.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC051089.1, AK008688.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849377, SAMN00849378
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-77                AC100729.21        104083-104159
            78-434              AK008688.1         8-364
            435-435             AC100729.21        112614-112614
            436-543             AK008688.1         366-473
            544-544             AC100729.21        115294-115294
            545-1937            AK008688.1         475-1867
            1938-1941           AC100729.21        137022-137025
FEATURES             Location/Qualifiers
     source          1..1941
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 33.7 cM"
     gene            1..1941
                     /gene="Cyp2c65"
                     /gene_synonym="2210009K14Rik"
                     /note="cytochrome P450, family 2, subfamily c, polypeptide
                     65"
                     /db_xref="GeneID:72303"
                     /db_xref="MGI:MGI:1919553"
     exon            1..192
                     /gene="Cyp2c65"
                     /gene_synonym="2210009K14Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             25..1497
                     /gene="Cyp2c65"
                     /gene_synonym="2210009K14Rik"
                     /EC_number="1.14.14.1"
                     /note="cytochrome P450, 2c65"
                     /codon_start=1
                     /product="cytochrome P450, family 2, subfamily c,
                     polypeptide 65 precursor"
                     /protein_id="NP_082467.2"
                     /db_xref="CCDS:CCDS29791.1"
                     /db_xref="GeneID:72303"
                     /db_xref="MGI:MGI:1919553"
                     /translation="MVLGVFLGLLLTCLLLLSLWRQNSQRRNLPPGPTPLPIIGNILQ
                     LDLKDISKSLRNFSKVYGPVFTLYLGRNPAVVLHGYEAVKEAFTDHGEEFAGRGVFPV
                     FDKFKKNCGVVFSSGRTWKEMRRFSLMTLRNFGMGRRSIEDRIQEEARCLVDELRKTK
                     GEPCDPTFILGCAPCNVICSIVFQNRFDYKDQEFLTFLDILNENVEILSSPWIQICNN
                     FPAVIDYLPGRHRKLHKNFAFAEHYFLSKVKQHQESLDINNPRDFIDCFLIKMEQEKH
                     NPKTEFTCENLVFTASDLFAAGTETTSTTLRYSLLLLLKYPEVTAKVQEEIDCVIGRH
                     RSPCMQDRHSMPYTDAVLHEIQRYIDLLPTSLPHAVTRDVKFREYLIPKGTTVIASLT
                     SVLYDDKEFPNPEKFDPSHFLDERGKFKKSDYFFPFSTGKRICVGEGLARAELFLFLT
                     TILQNFNLKSPVDLKDLDTTPVANGFASVPPKFQICFIPI"
     exon            193..355
                     /gene="Cyp2c65"
                     /gene_synonym="2210009K14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            356..505
                     /gene="Cyp2c65"
                     /gene_synonym="2210009K14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            506..666
                     /gene="Cyp2c65"
                     /gene_synonym="2210009K14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            667..843
                     /gene="Cyp2c65"
                     /gene_synonym="2210009K14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            844..985
                     /gene="Cyp2c65"
                     /gene_synonym="2210009K14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            986..1173
                     /gene="Cyp2c65"
                     /gene_synonym="2210009K14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1174..1315
                     /gene="Cyp2c65"
                     /gene_synonym="2210009K14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1316..1941
                     /gene="Cyp2c65"
                     /gene_synonym="2210009K14Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atatcttaag aagagaagca aacaatggtt ctaggtgtgt ttctggggct tcttctcaca
       61 tgtctgcttc ttctttcact atggaggcag aattctcaga gaagaaacct tcctcctggc
      121 cccacacctc tccccatcat tggaaatatt cttcagctag atcttaagga catcagcaaa
      181 tctctgagga atttttcaaa agtctatggc cctgtgttca ctctgtactt gggcaggaat
      241 cctgctgtgg tgttacatgg atatgaagct gtgaaagaag cctttactga tcatggggag
      301 gagtttgctg gaagaggagt ttttccagtg tttgataagt ttaagaaaaa ctgcggggtt
      361 gttttcagca gtgggaggac ctggaaagag atgagacgct tctcactcat gactctgcga
      421 aactttggga tggggaggag gagcattgag gaccgaattc aagaggaggc tcgctgtctt
      481 gtggatgaat tgaggaaaac caaaggtgaa ccctgtgatc ccaccttcat cctcggctgt
      541 gctccttgca atgtcatctg ctccattgtt ttccagaatc gttttgatta taaagatcag
      601 gaattcctta ccttcttaga catcttaaat gaaaatgtgg agattctgag ttccccttgg
      661 attcagattt gcaataattt tcctgctgtc attgattatc taccaggaag acacagaaaa
      721 ttacataaaa attttgcctt tgcagaacat tactttttgt caaaagtaaa acagcatcaa
      781 gagtcactgg atattaacaa tcctcgggac tttattgatt gtttcctgat caaaatggaa
      841 caggaaaagc acaacccaaa gacggagttt acttgtgaga acttggtctt cacagcatct
      901 gatctgtttg ctgctgggac agagacaaca agcacaaccc tgaggtactc tctgctgctc
      961 ctgctcaagt atccagaagt cacagccaaa gtccaggaag agatcgactg tgtgattggc
     1021 agacacagga gcccctgcat gcaggacagg catagcatgc cctacactga tgctgtgttg
     1081 catgagatcc agagatacat tgatctcctt cccaccagcc ttccccatgc cgtgacccgt
     1141 gacgtgaaat tcagagagta tctcattccc aagggcacca ctgtcatagc atcactgact
     1201 tctgtgctat atgatgataa agaattcccc aacccagaga agtttgaccc cagtcacttt
     1261 ctggatgagc gtggcaagtt taagaaaagt gactactttt ttcctttctc aacaggaaaa
     1321 cggatttgtg tgggagaggg tctggctcga gcagaattat ttttattcct gaccaccatt
     1381 ttacagaact ttaacttgaa atctccagtt gatctaaaag accttgatac tactccagtt
     1441 gccaatggat ttgcttctgt gccacccaag ttccagatat gcttcattcc catctaaatg
     1501 gatttccccc taaagctctt tccttgaggg tatagcttac ctcttctgtc aggcatgtct
     1561 ctctgaccct atcaccagag ttctgggatt ccatatatag ccctgcacaa actgatctat
     1621 gtccttcttt atacataaga caaaatagta ataaactgaa ataatgtccc aagatgtttc
     1681 ttcaccataa tacacacaaa ggaagcatga catctctggc catctatctc ttaaagatac
     1741 aggaaatgcc tatcttctat ttaaggcaat tattagggtt actgcaaagc aagtctgcaa
     1801 ttccctatgc tatgcaatga tttattgatt tcagccctgt tcttatctga tggtgaacta
     1861 ctaacatatt attatcttaa aactgagaaa tatgacagtt ttaaagcact gtgcgtttta
     1921 aataaaagta ttataattct g
//
