LOCUS       NM_206537               1781 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus cytochrome P450, family 2, subfamily c, polypeptide 54
            (Cyp2c54), mRNA.
ACCESSION   NM_206537 XM_904151
VERSION     NM_206537.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1781)
  AUTHORS   Kasai,F., Yoshihara,M., Matsukuma,S., O'Brien,P. and
            Ferguson-Smith,M.A.
  TITLE     Emergence of complex rearrangements at translocation breakpoints in
            a transgenic mouse; implications for mechanisms involved in the
            formation of chromosome rearrangements
  JOURNAL   Cytogenet Genome Res 119 (1-2), 83-90 (2007)
   PUBMED   18160786
REFERENCE   2  (bases 1 to 1781)
  AUTHORS   Wang,H., Zhao,Y., Bradbury,J.A., Graves,J.P., Foley,J.,
            Blaisdell,J.A., Goldstein,J.A. and Zeldin,D.C.
  TITLE     Cloning, expression, and characterization of three new mouse
            cytochrome p450 enzymes and partial characterization of their fatty
            acid oxidation activities
  JOURNAL   Mol Pharmacol 65 (5), 1148-1158 (2004)
   PUBMED   15102943
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BF659738.1, AI181879.1, AI047349.1 and AI046359.1.
            
            On Jun 19, 2008 this sequence version replaced NM_206537.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849386
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-471               BF659738.1         1-471
            472-798             AI181879.1         461-787
            799-1310            AI047349.1         235-746
            1311-1781           AI046359.1         1-471               c
FEATURES             Location/Qualifiers
     source          1..1781
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 34.24 cM"
     gene            1..1781
                     /gene="Cyp2c54"
                     /gene_synonym="EG404195"
                     /note="cytochrome P450, family 2, subfamily c, polypeptide
                     54"
                     /db_xref="GeneID:404195"
                     /db_xref="MGI:MGI:3642960"
     exon            1..170
                     /gene="Cyp2c54"
                     /gene_synonym="EG404195"
                     /inference="alignment:Splign:2.1.0"
     CDS             3..1475
                     /gene="Cyp2c54"
                     /gene_synonym="EG404195"
                     /EC_number="1.14.14.1"
                     /note="CYPIIC54"
                     /codon_start=1
                     /product="cytochrome P450 2C54"
                     /protein_id="NP_996260.1"
                     /db_xref="CCDS:CCDS29800.1"
                     /db_xref="GeneID:404195"
                     /db_xref="MGI:MGI:3642960"
                     /translation="MDPILVLVLTLSCLFLLSLWRQSYERGKLPPGPTPLPIIGNILQ
                     IDVKDICQSFTNLSRVYGPVYTLYLGRKPTVVLHGYEAVKEALVDHGDVFAGRGRLPV
                     FDKATNGMGIGFSNGSVWKNTRHFSLMTLRNLGMGKRSIEDRVQEEARCLVEELRKTN
                     GSPCDPTFILGCAPCNVICSIIFQDRFDYKDRDFLNLLEKLDEISKILSTPWLQVCNT
                     FPALLDYCPGSHNQFFKNYAYIKNFLLEKIREHKESLDVTIPRDFIDYFLIKGAQEDD
                     NHPLKNNFEHLAITVTDLFIGGTESMSTTLRYALLLLLKYPHVTAKVQEEIEHVIGKH
                     RRPCMQDRSHMPYTNAMIHEVQRFIDLVPNNLPHEVTCDIKFRNYFIPKGTTVITSLS
                     SVLRDSKEFPNPEKFDPGHFLDENGKFKKSDYFMPFSTGKRICAGEGLARMELFLFLT
                     SILQNFNLKPLVHPKDIDITPMLIGLGSVPPAFQLCFIPS"
     exon            171..333
                     /gene="Cyp2c54"
                     /gene_synonym="EG404195"
                     /inference="alignment:Splign:2.1.0"
     exon            334..483
                     /gene="Cyp2c54"
                     /gene_synonym="EG404195"
                     /inference="alignment:Splign:2.1.0"
     exon            484..644
                     /gene="Cyp2c54"
                     /gene_synonym="EG404195"
                     /inference="alignment:Splign:2.1.0"
     exon            645..821
                     /gene="Cyp2c54"
                     /gene_synonym="EG404195"
                     /inference="alignment:Splign:2.1.0"
     exon            822..963
                     /gene="Cyp2c54"
                     /gene_synonym="EG404195"
                     /inference="alignment:Splign:2.1.0"
     exon            964..1151
                     /gene="Cyp2c54"
                     /gene_synonym="EG404195"
                     /inference="alignment:Splign:2.1.0"
     exon            1152..1293
                     /gene="Cyp2c54"
                     /gene_synonym="EG404195"
                     /inference="alignment:Splign:2.1.0"
     exon            1294..1772
                     /gene="Cyp2c54"
                     /gene_synonym="EG404195"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1750..1755
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cyp2c54"
                     /gene_synonym="EG404195"
                     /note="hexamer: AATAAA"
     polyA_site      1772
                     /gene="Cyp2c54"
                     /gene_synonym="EG404195"
                     /note="major polyA site"
ORIGIN      
        1 ccatggatcc aatcctggtc ctggtgctca ctctctcctg tctgtttctc ctctcactct
       61 ggagacagag ctatgaaaga gggaagcttc cccctggccc cactcctctt ccaattattg
      121 gaaacatcct tcagatagat gtgaaggaca tctgccaatc cttcaccaat ttatcaagag
      181 tttatggtcc tgtgtatact ctatatttgg gcaggaagcc cactgtggtg ttgcatggat
      241 atgaggcagt gaaggaagct ctggttgacc atggggatgt ctttgctgga aggggaaggc
      301 tcccagtttt tgataaagct actaatggaa tgggcattgg atttagtaat ggaagtgtat
      361 ggaaaaacac gaggcacttc tcactcatga ctctgcggaa tttaggcatg ggaaaaagga
      421 gcattgagga ccgtgttcaa gaggaagcac gttgccttgt ggaggaactt aggaaaacca
      481 atggctcacc ctgtgatccc accttcatcc tgggctgtgc tccctgcaat gtcatctgct
      541 caattatttt ccaggatcgt tttgattata aagatcggga ttttctaaac ttgttggaaa
      601 aactggatga aatatccaag attctgagca ccccctggtt gcaggtttgc aatacatttc
      661 ctgctctgct tgattattgt ccaggaagtc ataaccaatt ttttaaaaat tatgcttata
      721 ttaaaaattt ccttttggag aaaataaggg aacataaaga atcattggat gttacaattc
      781 ctcgggactt tattgattat ttcctaatta aaggagccca ggaagatgac aatcatcctt
      841 tgaaaaataa ttttgaacac ctggcaataa cagtgactga tctttttatt ggtgggacag
      901 agtcaatgag cacaacactg agatatgctc tcctactcct attgaagtac ccacatgtca
      961 cagctaaagt ccaggaagaa attgagcatg tgatcggcaa gcaccgaaga ccatgcatgc
     1021 aggacaggag ccacatgccc tatacaaatg ccatgattca tgaggtccag agattcattg
     1081 accttgtccc caacaacctg ccccatgaag tgacctgtga cattaaattc aggaactact
     1141 tcattcccaa gggaacaact gtaataacat cactgtcatc agtgctgcgt gatagcaagg
     1201 agttccccaa cccagagaag tttgaccctg ggcactttct agatgagaat ggaaagttta
     1261 aaaaaagtga ctacttcatg ccattctcaa cagggaaacg gatatgtgca ggagagggcc
     1321 tggcacgcat ggagctgttc ctgttcctaa ccagcatttt acagaacttc aacctgaaac
     1381 ctctggttca cccaaaggac atagatataa ccccaatgct cattggattg ggctcagtgc
     1441 ctcctgcttt ccagctctgc ttcattcctt cctgaaaatc aaatgcctgg ctccactgct
     1501 ttccatactg aacacactgc cttttatcca tttcttttgt gtcctcataa tttcataagc
     1561 atctaatgaa catacattta ccaatttgca aatcctgcac aaatattttt gactgttcct
     1621 attttctaaa acactattac catatgctgt gatgatatgg acctgattcc aagttaaata
     1681 tactctcata aaattgaaat tactattgta ggttaattca ctgtcacttc tcttctgcat
     1741 tttcttaata ataaattgtt ttggtatacc taaaaaaaaa a
//
