LOCUS       NM_001162865            1297 bp    mRNA    linear   ROD 19-DEC-2023
DEFINITION  Mus musculus cylicin, basic protein of sperm head cytoskeleton 2
            (Cylc2), mRNA.
ACCESSION   NM_001162865
VERSION     NM_001162865.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1297)
  AUTHORS   Schneider S, Kovacevic A, Mayer M, Dicke AK, Arevalo L, Koser SA,
            Hansen JN, Young S, Brenker C, Kliesch S, Wachten D, Kirfel G,
            Struenker T, Tuttelmann F and Schorle H.
  TITLE     Cylicins are a structural component of the sperm calyx being
            indispensable for male fertility in mice and human
  JOURNAL   Elife 12, 86100 (2023)
   PUBMED   38013430
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1297)
  AUTHORS   Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V,
            Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs
            P, Fu J, Nefedov M, de Jong PJ, Stewart AF and Bradley A.
  TITLE     A conditional knockout resource for the genome-wide study of mouse
            gene function
  JOURNAL   Nature 474 (7351), 337-342 (2011)
   PUBMED   21677750
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL772238.7.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK015651.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN00849384
                                           [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on computational evidence
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-45                AL772238.7         29257-29301
            46-86               AL772238.7         35001-35041
            87-208              AL772238.7         37704-37825
            209-661             AL772238.7         40690-41142
            662-1297            AL772238.7         41872-42507
FEATURES             Location/Qualifiers
     source          1..1297
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 27.27 cM"
     gene            1..1297
                     /gene="Cylc2"
                     /gene_synonym="4930488P18Rik"
                     /note="cylicin, basic protein of sperm head cytoskeleton
                     2"
                     /db_xref="GeneID:74914"
                     /db_xref="MGI:MGI:1922164"
     exon            1..45
                     /gene="Cylc2"
                     /gene_synonym="4930488P18Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             29..1297
                     /gene="Cylc2"
                     /gene_synonym="4930488P18Rik"
                     /codon_start=1
                     /product="cylicin-2"
                     /protein_id="NP_001156337.1"
                     /db_xref="CCDS:CCDS71386.1"
                     /db_xref="GeneID:74914"
                     /db_xref="MGI:MGI:1922164"
                     /translation="MSIPRFLKVTYGAYDNYIPVSELSKKSWNQQYFSLAFPKPPRPG
                     KKRRSLPSQLQNNTAPVIDEEKLGVHRPPLWMHRSLMRISERPSVYLAARKGLIPKPL
                     HFGKGESKSVGTHKSLASEKTKKEVKMKKDGFEAKEKTALKTDKEGSPKPAKKNIPRD
                     SQKDKGRVSSDSEGEKAGVKKGSKKVKNTPKGKDSASESEGEKAGSKKEAKTTKKGSK
                     DKVSATESGGEKAGSKKEAKATKKGSKDKVSGTESGGEKAGSKKEAKTTKKESKDKVS
                     ATESGGEKAGSKKEAKDDKKDATSSQETLLSTAADKDGKKKEEKPVKQSSKSKDTVKD
                     SASEKGDEKKEDKKEGKKEKKKKDGEGKEGGKKEKKDKKDKKDKKDKKDKKDKKDKKE
                     KDKKDKKDKKDKKDKKDKKDKKDKKDKKAK"
     exon            46..86
                     /gene="Cylc2"
                     /gene_synonym="4930488P18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            87..208
                     /gene="Cylc2"
                     /gene_synonym="4930488P18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            209..661
                     /gene="Cylc2"
                     /gene_synonym="4930488P18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            662..1297
                     /gene="Cylc2"
                     /gene_synonym="4930488P18Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggccctggc acgtcacagg tgggagaaat gtctatacca agattcctaa aagtaacata
       61 tggagcatac gataattaca ttccagtcag tgagttaagc aaaaaatcat ggaatcagca
      121 atacttttcc ctggcatttc ccaaaccacc aaggccagga aaaaaacgga gatcactacc
      181 ttcccagtta cagaacaata cagctcctgt aattgatgaa gaaaaattag gagttcacag
      241 accaccatta tggatgcacc gttccctgat gagaatatcc gagagaccat ccgtttattt
      301 agctgccagg aagggcctta taccaaaacc acttcatttt ggcaagggag agtcgaaaag
      361 cgtgggcaca cacaagtctt tggcttcaga aaaaacaaag aaagaagtaa aaatgaaaaa
      421 agatggattt gaagcaaaag agaagacagc gttaaagaca gacaaggagg gaagtcccaa
      481 accagctaaa aagaacattc caagggattc acaaaaggac aagggaagag tatcttcaga
      541 ttctgaaggc gaaaaggctg gtgtgaagaa gggatccaag aaagttaaaa atacacctaa
      601 gggtaaagat tcagcctcag aatctgaggg tgaaaaggct ggatccaaga aggaagccaa
      661 gaccactaaa aaaggatcca aggataaagt gtcagccaca gaatctggag gtgaaaaggc
      721 tggttcgaag aaggaagcca aggccactaa aaaaggatcc aaggataaag tgtcaggcac
      781 agaatctgga ggtgaaaagg ctggttcgaa gaaggaagcc aagaccacta aaaaagaatc
      841 caaggataaa gtgtcagcca cagaatctgg aggtgaaaag gctggttcga agaaggaagc
      901 caaggatgat aaaaaagatg caacgagctc acaagaaaca cttttaagta cagcagctga
      961 caaagatggc aaaaagaagg aagaaaaacc agttaaacag agttcaaaaa gcaaagatac
     1021 ggttaaagat tctgcaagtg aaaagggaga tgaaaagaaa gaggacaaga aggaagggaa
     1081 aaaggagaag aaaaagaaag atggagaagg aaaagagggt ggtaagaaag agaagaaaga
     1141 caagaaggac aagaaagaca aaaaggacaa gaaggacaag aaagacaaga aagacaagaa
     1201 agaaaaagac aagaaagaca agaaagataa gaaagataag aaagataaga aagataagaa
     1261 agacaagaaa gacaagaaag acaagaaagc aaagtag
//
