LOCUS       NM_133769               6385 bp    mRNA    linear   ROD 24-DEC-2024
DEFINITION  Mus musculus cytoplasmic FMR1 interacting protein 2 (Cyfip2),
            transcript variant 1, mRNA.
ACCESSION   NM_133769
VERSION     NM_133769.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6385)
  AUTHORS   Balekoglu,N., Michaud,J.F., Sauve,R., Ayinde,K.S., Lin,S., Liu,Y.,
            Kramer,D.A., Zhang,K., Steffen,A., Stradal,T., Angers,S., Chen,B.,
            Yam,P.T. and Charron,F.
  TITLE     The WAVE regulatory complex interacts with Boc and is required for
            Shh-mediated axon guidance
  JOURNAL   iScience 27 (12), 111333 (2024)
   PUBMED   39640588
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6385)
  AUTHORS   Zhang,Y., Kang,H.R., Jun,Y., Kang,H., Bang,G., Ma,R., Ju,S.,
            Yoon,D.E., Kim,Y., Kim,K., Kim,J.Y. and Han,K.
  TITLE     Neurodevelopmental disorder-associated CYFIP2 regulates
            membraneless organelles and eIF2alpha phosphorylation via protein
            interactors and actin cytoskeleton
  JOURNAL   Hum Mol Genet 33 (19), 1671-1687 (2024)
   PUBMED   38981622
REFERENCE   3  (bases 1 to 6385)
  AUTHORS   Nguyen,C.D.K., Colon-Emeric,B.A., Murakami,S., Shujath,M.N.Y. and
            Yi,C.
  TITLE     PRMT1 promotes epigenetic reprogramming associated with acquired
            chemoresistance in pancreatic cancer
  JOURNAL   Cell Rep 43 (5), 114176 (2024)
   PUBMED   38691454
REFERENCE   4  (bases 1 to 6385)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   5  (bases 1 to 6385)
  AUTHORS   Rivera-Garcia,L.G., Francis-Malave,A.M., Castillo,Z.W., Uong,C.D.,
            Wilson,T.D., Ferchmin,P.A., Eterovic,V., Burton,M.D. and
            Carrasquillo,Y.
  TITLE     Anti-hyperalgesic and anti-inflammatory effects of 4R-tobacco
            cembranoid in a mouse model of inflammatory pain
  JOURNAL   J Inflamm (Lond) 21 (1), 2 (2024)
   PUBMED   38267952
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6385)
  AUTHORS   Levanon,E.Y., Hallegger,M., Kinar,Y., Shemesh,R.,
            Djinovic-Carugo,K., Rechavi,G., Jantsch,M.F. and Eisenberg,E.
  TITLE     Evolutionarily conserved human targets of adenosine to inosine RNA
            editing
  JOURNAL   Nucleic Acids Res 33 (4), 1162-1168 (2005)
   PUBMED   15731336
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 6385)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Hara,Y., Nagase,T.,
            Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: I. The complete nucleotide sequences of 100 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 9 (5), 179-188 (2002)
   PUBMED   12465718
REFERENCE   8  (bases 1 to 6385)
  AUTHORS   McIntire,J.J., Umetsu,S.E., Akbari,O., Potter,M., Kuchroo,V.K.,
            Barsh,G.S., Freeman,G.J., Umetsu,D.T. and DeKruyff,R.H.
  TITLE     Identification of Tapr (an airway hyperreactivity regulatory locus)
            and the linked Tim gene family
  JOURNAL   Nat Immunol 2 (12), 1109-1116 (2001)
   PUBMED   11725301
REFERENCE   9  (bases 1 to 6385)
  AUTHORS   Schenck,A., Bardoni,B., Moro,A., Bagni,C. and Mandel,J.L.
  TITLE     A highly conserved protein family interacting with the fragile X
            mental retardation protein (FMRP) and displaying selective
            interactions with FMRP-related proteins FXR1P and FXR2P
  JOURNAL   Proc Natl Acad Sci U S A 98 (15), 8844-8849 (2001)
   PUBMED   11438699
REFERENCE   10 (bases 1 to 6385)
  AUTHORS   Saller,E., Tom,E., Brunori,M., Otter,M., Estreicher,A., Mack,D.H.
            and Iggo,R.
  TITLE     Increased apoptosis induction by 121F mutant p53
  JOURNAL   EMBO J 18 (16), 4424-4437 (1999)
   PUBMED   10449408
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ115523.1, AK147586.1 and CD773967.1.
            
            On Nov 15, 2011 this sequence version replaced NM_133769.2.
            
            Transcript Variant: This variant (1) is the predominant transcript.
            Variants 1-3 encode the same protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK147586.1, AK147971.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-8                 CJ115523.1         2-9
            9-6359              AK147586.1         2-6352
            6360-6385           CD773967.1         1-26                c
FEATURES             Location/Qualifiers
     source          1..6385
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 27.61 cM"
     gene            1..6385
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /note="cytoplasmic FMR1 interacting protein 2"
                     /db_xref="GeneID:76884"
                     /db_xref="MGI:MGI:1924134"
     exon            1..132
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            133..272
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     CDS             156..3917
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /note="p53-inducible protein 121"
                     /codon_start=1
                     /product="cytoplasmic FMR1-interacting protein 2"
                     /protein_id="NP_598530.2"
                     /db_xref="CCDS:CCDS24573.1"
                     /db_xref="GeneID:76884"
                     /db_xref="MGI:MGI:1924134"
                     /translation="MTTHVTLEDALSNVDLLEELPLPDQQPCIEPPPSSIMYQANFDT
                     NFEDRNAFVTGIARYIEQATVHSSMNEMLEEGHDYAVMLYTWRSCSRAIPQVKCNEQP
                     NRVEIYEKTVEVLEPEVTKLMKFMYFQRKAIERFCSEVKRLCHAERRKDFVSEAYLLT
                     LGKFINMFAVLDELKNMKCSVKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHN
                     RITQCLHQQLEVIPGYEELLADIVNICVDYYENKMYLTPSEKHMLLKVMGFGLYLMDG
                     NVSNIYKLDAKKRINLSKIDKFFKQLQVVPLFGDMQIELARYIKTSAHYEENKSKWTC
                     TQSSISPQYNICEQMVQIRDDHIRFISELARYSNSEVVTGSGLDSQKSDEEYRELFDL
                     ALRGLQLLSKWSAHVMEVYSWKLVHPTDKFCNKDCPGTAEEYERATRYNYTSEEKFAF
                     VEVIAMIKGLQVLMGRMESVFNQAIRNTIYAALQDFAQVTLREPLRQAVRKKKNVLIS
                     VLQAIRKTICDWEGGREPPNDPCLRGEKDPKGGFDIKVPRRAVGPSSTQLYMVRTMLE
                     SLIADKSGSKKTLRSSLDGPIVLAIEDFHKQSFFFTHLLNISEALQQCCDLSQLWFRE
                     FFLELTMGRRIQFPIEMSMPWILTDHILETKEPSMMEYVLYPLDLYNDSAYYALTKFK
                     KQFLYDEIEAEVNLCFDQFVYKLADQIFAYYKAMAGSVLLDKRFRAECKNYGVIIPYP
                     PSNRYETLLKQRHVQLLGRSIDLNRLITQRISAAMYKSLDQAISRFESEDLTSIVELE
                     WLLEINRLTHRLLCKHMTLDSFDAMFREANHNVSAPYGRITLHVFWELNFDFLPNYCY
                     NGSTNRFVRTAIPFTQEPQRDKPANVQPYYLYGSKPLNIAYSHIYSSYRNFVGPPHFK
                     TICRLLGYQGIAVVMEELLKIVKSLLQGTILQYVKTLIEVMPKICRLPRHEYGSPGIL
                     EFFHHQLKDIIEYAELKTDVFQSLREVGNAILFCLLIEQALSQEEVCDLLHAAPFQNI
                     LPRVYIKEGERLEVRMKRLEAKYAPLHLVPLIERLGTPQQIAIAREGDLLTKERLCCG
                     LSMFEVILTRIRSYLQDPIWRGPPPTNGVMHVDECVEFHRLWSAMQFVYCIPVGTNEF
                     TAEQCFGDGLNWAGCSIIVLLGQQRRFDLFDFCYHLLKVQRQDGKDEIIKNVPLKKMA
                     DRIRKYQILNNEVFAILNKYMKSVETDSSTVEHVRCFQPPIHQSLATTC"
     exon            273..362
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            363..440
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            441..542
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            543..724
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            725..821
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            822..950
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            951..1055
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            1056..1147
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            1148..1265
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            1266..1385
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            1386..1511
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            1512..1678
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            1679..1826
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            1827..1980
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            1981..2137
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            2138..2234
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            2235..2311
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            2312..2420
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            2421..2540
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            2541..2740
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            2741..2828
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            2829..2972
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            2973..3063
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            3064..3194
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            3195..3267
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            3268..3362
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            3363..3601
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            3602..3749
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     exon            3750..6368
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6336..6341
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /note="hexamer: ATTAAA"
     polyA_site      6362
                     /gene="Cyfip2"
                     /gene_synonym="1500004I01Rik; 6430511D02Rik; mKIAA1168;
                     Pir121"
                     /note="major polyA site"
ORIGIN      
        1 ggagaggcgg ggccgcgggc ggggcgcggc ggtccgccgg cgcagcggcg gagcggggct
       61 aagcatcctg cgccccggcg cggggccctg cggtagcctc gggtccctcc cctggacctg
      121 ccaccgagcc agtgtgaaag acaggcgccg cagccatgac cacccacgtc actttggaag
      181 atgccctgtc caacgtggac ctgctggagg aactgcccct cccagaccag cagccatgta
      241 tcgagccccc gccatcctcc atcatgtacc aggctaactt tgacacgaac ttcgaggaca
      301 ggaatgcatt tgtcacgggc attgcaaggt acattgagca ggcaacggtc cactccagca
      361 tgaatgaaat gctggaggag ggccacgact atgcagtcat gctgtacacc tggcgcagct
      421 gctcccgggc catcccgcag gtgaagtgca atgagcagcc caatcgggtc gagatctacg
      481 agaagacggt ggaggtgctg gagccagagg tcaccaagct catgaagttc atgtactttc
      541 agcgcaaggc catcgagcgc ttctgtagcg aggtgaagcg gctgtgtcac gctgagcgca
      601 ggaaggactt tgtctctgag gcctacctgc tgacgctggg caagttcatc aacatgttcg
      661 cggtcttgga cgagctaaag aacatgaagt gcagtgtcaa gaatgaccac tctgcctaca
      721 agagagcagc acagttccta aggaagatgg cggaccccca gtccatccag gaatctcaga
      781 acctgtccat gttcctggcc aatcacaaca ggatcaccca gtgtcttcac cagcaactgg
      841 aagtgatccc gggctatgag gagctgctgg cagacattgt caacatctgt gttgattact
      901 atgagaataa gatgtacctg acgcccagtg aaaagcacat gttgctcaag gtgatgggct
      961 ttggtctcta tctgatggac ggaaatgtca gtaacattta caaactggat gccaagaaga
     1021 gaatcaacct tagcaaaatt gataagtttt ttaagcagct gcaggtggta ccccttttcg
     1081 gcgacatgca gatagagctg gccagataca ttaagaccag tgctcactat gaagagaaca
     1141 agtccaagtg gacatgcact cagagcagca tcagccccca gtacaacatc tgtgagcaga
     1201 tggttcagat ccgggatgat cacatccgct tcatctctga gctggctcgc tacagcaaca
     1261 gcgaggtggt gacaggctca gggctggaca gccagaagtc ggatgaagag taccgggagc
     1321 tttttgacct ggccctgcga ggcctgcagc ttctatccaa gtggagtgcc catgtcatgg
     1381 aggtgtactc ttggaagctg gttcacccca cagacaagtt ctgcaacaag gactgcccgg
     1441 gcaccgcgga agagtacgag agagccacgc gctacaatta taccagcgag gagaagtttg
     1501 cctttgtgga ggtgattgcc atgatcaagg gtttgcaggt gctcatggga aggatggaga
     1561 gtgtcttcaa ccaggccatc cgcaacacta tctacgcagc cctgcaggat ttcgcccagg
     1621 tgacgctgcg ggagccgttg cggcaagcag ttcgaaagaa aaagaatgtc cttatcagcg
     1681 ttctgcaagc aattcgaaag accatctgtg actgggaggg aggccgagag ccccccaatg
     1741 acccatgctt aagaggggag aaggacccca aaggtggctt tgacatcaag gtgccccgcc
     1801 gtgctgtggg tccatccagc acacagctgt acatggtgcg caccatgctt gagtcactca
     1861 tcgcagacaa gagcggctcc aagaagacgc tcagaagcag cctggatggc cctatcgtcc
     1921 ttgccataga ggacttccac aagcagtcct tctttttcac acacctgctt aacatcagcg
     1981 aggctcttca gcagtgctgt gacctctccc agctctggtt ccgagaattc ttcctggagt
     2041 tgaccatggg ccggcgaatc cagttcccga ttgagatgtc catgccctgg attctaacgg
     2101 accatattct ggaaaccaaa gaaccttcca tgatggagta tgtcctctac cccttggatc
     2161 tgtacaacga cagcgcctac tatgccctca ccaaattcaa aaagcagttc ctgtatgacg
     2221 agatcgaagc cgaggtaaac ctgtgttttg atcagtttgt ctacaagctg gctgaccaga
     2281 tcttcgccta ctacaaagcc atggccggca gtgtcctgct ggataaacgt tttagagctg
     2341 agtgtaagaa ctatggggtg atcataccgt acccgccatc caaccgctac gagacactgc
     2401 tgaagcagag acatgtccag ctgttgggga gatcaattga cttgaacaga ctcatcaccc
     2461 agcggatctc tgctgccatg tacaagtcct tggaccaggc catcagccgc tttgagagtg
     2521 aagacctgac ctccattgtg gagctggagt ggctgctgga gattaaccga ctcacacacc
     2581 gactcctctg taagcacatg acgctagaca gcttcgatgc catgttccga gaagccaatc
     2641 ataacgtgtc tgccccttac ggccgcatca ccctgcatgt cttctgggag ctgaactttg
     2701 actttctccc caactactgc tataatggat ccacaaaccg ttttgtccga actgccatcc
     2761 ctttcaccca agaaccacaa cgggataagc ccgccaatgt ccagccttat tacctctatg
     2821 gatccaagcc tctcaacatt gcctacagcc acatctatag ctcctaccgg aactttgtgg
     2881 ggccccctca cttcaagacc atctgcagac tgttgggcta ccagggcatc gctgtggtca
     2941 tggaggaact gctgaaaatc gtcaagagct tgctccaagg caccatcctg cagtacgtga
     3001 agacgctcat agaggtgatg ccgaaaatct gtcgtttgcc tcggcacgag tacggctctc
     3061 caggaatcct ggagttcttc caccaccaac tgaaggacat catcgagtat gcagaactca
     3121 aaacagacgt gttccagagc ctccgagagg tgggcaacgc catcctgttc tgcctcctca
     3181 tagagcaagc tctgtctcag gaggaagtct gtgatttgct ccatgctgca cccttccaaa
     3241 acattctgcc ccgagtctac atcaaagagg gggagcgcct ggaagtccgg atgaagcgcc
     3301 tcgaggccaa gtacgcccca cttcacctgg ttcccctgat agagcggctg gggacgcctc
     3361 agcaaatcgc catcgctcgg gagggtgacc tgctgaccaa ggagcggctc tgctgcggcc
     3421 tgtccatgtt tgaggtcatc ctgacccgaa tccggagcta cctgcaggac cccatctgga
     3481 ggggcccgcc acccaccaat ggcgtcatgc atgtggatga gtgtgtggag tttcaccggc
     3541 tgtggagtgc catgcagttt gtctactgta tccctgtggg gaccaacgag ttcacagctg
     3601 agcagtgctt cggtgacggc ttgaactggg ccggctgctc catcattgtc ttgctgggcc
     3661 agcagcggcg ctttgacctg tttgacttct gttatcatct gctgaaggtg cagaggcagg
     3721 acgggaagga tgagatcatt aagaatgtgc ctctgaagaa gatggctgac cgcatcagga
     3781 agtaccagat cttgaacaat gaggtttttg ccatcctgaa caagtacatg aagtctgtag
     3841 agacagacag ttccaccgta gagcatgtgc gctgcttcca gcccccaatc caccagtcat
     3901 tggccaccac ctgctaggta gaaaaccgtg cagaccttca acctggagga ggaggaggag
     3961 gaggagagaa cacagtgacc agcctgcagc aggtccagtt gacagtgtgt ggacaggtct
     4021 ggaaggaaaa gaaaacctcc ccaacacatc tctaccactc ccaagggctg ggctcccgca
     4081 tgttcctccc atgatatctc catggtggat tttccatagt gtaaatgaaa aaaaaaacaa
     4141 caaaaacaca gggcagtgtg tgctttcttt tctttttttc caccttatct gtattgaaga
     4201 gctactgttt ccaccctgca gctgcccact ccatctgcga ttacttccca agaccgcctc
     4261 cccaagtcgt aacctcctac ccgctatctg tatttgatcc agcactatag tcttagagac
     4321 atagaagaga agagtgtagc catagcagag atatcagcct ggcccattgg atatctcagc
     4381 ttactggccc atcttctgtg gcttctccct ccagttccct caccacagca cttcctgctc
     4441 gtgacattag ggattccacc accaaaatct gatccctggt gaaccaggaa gaggttgctg
     4501 ttgtcaagac aacagatgat gctgaccaag atcttttaca gcctccctaa gacccaccct
     4561 agaccttcct tacagaacag acctagagag aagaaagtaa ggcttgcaaa accacaccac
     4621 actgggtgga actaggtgaa gatgaccagg cctactgtga gggagagaga gagtcatcag
     4681 cacagggcaa aactccagat ccaaaggata aatgttaggc cttgttaaca gcgtgggaag
     4741 atgaggcact cctggtcctc aaacagaggc ttagcactga gccacatggg aatccacatg
     4801 gtccgtcata gcgctacaca tagcattcgt gagtgaccaa gtcagtggct gcttaacaca
     4861 gaacctaatc caggaaaatc ccccaagaaa gaaaacctaa aggggttacc ttaattggag
     4921 acagggtggc aaggaggaaa aatatttttg tcaacaagct tcctatcccc agacccctcc
     4981 cctcaaaagg aagtcttctt tgagctaact ggaatgttct catgtcggct actaaaagat
     5041 tcttggaatg ttcttttgct ctcaatgtcc tggtctctcc cttttgctca agctcagtca
     5101 tggggatgta ttaacttcta tgtttcagac taaaacaccc ctgcacagtc cccacaaata
     5161 gcacatcttt taaagagatt gcccaagtct ccatatagag ctagtcatct gacctgcaga
     5221 gaggacatag ccctgagctc ccaagacaca ggaataatag atattcctct accagcctgg
     5281 ggaggacaga agacaggagt aaccatcccc tgccccagga aggtgattgt tatccatcac
     5341 cgttttttta accacacaga gaagagaaga gatgtgcata atctgtactt tgccagacag
     5401 ggccatgtac cccagggtgg tcatataaat tagaatcctt aaggatggca caccagagtg
     5461 ttcctttctg gacactaact ttgaatctct gggaatagag ccagaagacc tgcctcttct
     5521 cagatatatc actgcacacc acatactcag accttgctgt agattggaca actctactaa
     5581 ctctgggtct ctctgagcaa gagtaggagc atttgtagtg tagggttgtg gtttgaaaca
     5641 gaaactgtcc agtcctcctg tctggcactg ttaattctta gtctgattat ttttcaatga
     5701 ccatagctgt atcccagagg cagattccac tttccagatc gtcagctctg gctggggata
     5761 gaatgtgata aacagacttt ccccgcttag tgtcccctca ctgctctgta gagatttggg
     5821 ctgttcataa ggccgccttc ctggcagctc atcccttcta ccctgcactc ctgaccccaa
     5881 cagttgaccc tctgggaaga gtcacattct gctcaagata tttgatccca ataaattgag
     5941 gtcctcgctt tgaggacaga gattccattt ttgcagcact tgcctgcaaa ctctggacaa
     6001 cttcaatgct ctttcctctc tagtggtcct tgccccccac ccctttgatt ttttttttaa
     6061 tgtatttaaa gatcaagaaa aaagcttaga ttttaaaatg ttttaaaaag aattctgttt
     6121 cagaaattgt caaatgtgta ccatatttgt attaagagtt gttggggatt ttttgtacaa
     6181 tgaatttaca tttatttatg gtgaacttat atttacgctt gtgatcaaat aatgatgtta
     6241 aattcttaaa tcctatttgc tatgcagctg aagatgatat tttgatttgt attttggggg
     6301 tacctgtgtt gagtcgataa aacattttca tctccattaa aactgcttcc aaaccagtta
     6361 aaccagcaaa aaaaaaaaaa aaaaa
//
