LOCUS       NM_025567               1534 bp    mRNA    linear   ROD 04-DEC-2024
DEFINITION  Mus musculus cytochrome c-1 (Cyc1), mRNA; nuclear gene for
            mitochondrial product.
ACCESSION   NM_025567
VERSION     NM_025567.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1534)
  AUTHORS   Vercellino,I. and Sazanov,L.A.
  TITLE     SCAF1 drives the compositional diversity of mammalian respirasomes
  JOURNAL   Nat Struct Mol Biol 31 (7), 1061-1071 (2024)
   PUBMED   38575788
REFERENCE   2  (bases 1 to 1534)
  AUTHORS   Lu,P., Wang,P., Wu,B., Wang,Y., Liu,Y., Cheng,W., Feng,X., Yuan,X.,
            Atteya,M.M., Ferro,H., Sugi,Y., Rydquist,G., Esmaily,M.,
            Butcher,J.T., Chang,C.P., Lenz,J., Zheng,D. and Zhou,B.
  TITLE     A SOX17-PDGFB signaling axis regulates aortic root development
  JOURNAL   Nat Commun 13 (1), 4065 (2022)
   PUBMED   35831318
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1534)
  AUTHORS   Vercellino,I. and Sazanov,L.A.
  TITLE     Structure and assembly of the mammalian mitochondrial supercomplex
            CIII2CIV
  JOURNAL   Nature 598 (7880), 364-367 (2021)
   PUBMED   34616041
REFERENCE   4  (bases 1 to 1534)
  AUTHORS   Li,Y., Ivica,N.A., Dong,T., Papageorgiou,D.P., He,Y., Brown,D.R.,
            Kleyman,M., Hu,G., Chen,W.W., Sullivan,L.B., Del Rosario,A.,
            Hammond,P.T., Vander Heiden,M.G. and Chen,J.
  TITLE     MFSD7C switches mitochondrial ATP synthesis to thermogenesis in
            response to heme
  JOURNAL   Nat Commun 11 (1), 4837 (2020)
   PUBMED   32973183
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1534)
  AUTHORS   Guo,R., Zong,S., Wu,M., Gu,J. and Yang,M.
  TITLE     Architecture of Human Mitochondrial Respiratory Megacomplex
            I2III2IV2
  JOURNAL   Cell 170 (6), 1247-1257 (2017)
   PUBMED   28844695
REFERENCE   6  (bases 1 to 1534)
  AUTHORS   Lanier,J., Dykes,I.M., Nissen,S., Eng,S.R. and Turner,E.E.
  TITLE     Brn3a regulates the transition from neurogenesis to terminal
            differentiation and represses non-neural gene expression in the
            trigeminal ganglion
  JOURNAL   Dev Dyn 238 (12), 3065-3079 (2009)
   PUBMED   19877281
REFERENCE   7  (bases 1 to 1534)
  AUTHORS   Mizuta,T., Shimizu,S., Matsuoka,Y., Nakagawa,T. and Tsujimoto,Y.
  TITLE     A Bax/Bak-independent mechanism of cytochrome c release
  JOURNAL   J Biol Chem 282 (22), 16623-16630 (2007)
   PUBMED   17409097
REFERENCE   8  (bases 1 to 1534)
  AUTHORS   Cipolat,S., Rudka,T., Hartmann,D., Costa,V., Serneels,L.,
            Craessaerts,K., Metzger,K., Frezza,C., Annaert,W., D'Adamio,L.,
            Derks,C., Dejaegere,T., Pellegrini,L., D'Hooge,R., Scorrano,L. and
            De Strooper,B.
  TITLE     Mitochondrial rhomboid PARL regulates cytochrome c release during
            apoptosis via OPA1-dependent cristae remodeling
  JOURNAL   Cell 126 (1), 163-175 (2006)
   PUBMED   16839884
REFERENCE   9  (bases 1 to 1534)
  AUTHORS   Hansen,T.M., Smith,D.J. and Nagley,P.
  TITLE     Smac/DIABLO is not released from mitochondria during apoptotic
            signalling in cells deficient in cytochrome c
  JOURNAL   Cell Death Differ 13 (7), 1181-1190 (2006)
   PUBMED   16239929
REFERENCE   10 (bases 1 to 1534)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK011288.1, AA738621.1 and AW121892.1.
            
            On Jul 12, 2018 this sequence version replaced NM_025567.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK011288.1, AK151299.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1194              AK011288.1         2-1195
            1195-1519           AA738621.1         165-489
            1520-1534           AW121892.1         1-15                c
FEATURES             Location/Qualifiers
     source          1..1534
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 35.74 cM"
     gene            1..1534
                     /gene="Cyc1"
                     /gene_synonym="2610002H19Rik; Cyct1"
                     /note="cytochrome c-1"
                     /db_xref="GeneID:66445"
                     /db_xref="MGI:MGI:1913695"
     exon            1..170
                     /gene="Cyc1"
                     /gene_synonym="2610002H19Rik; Cyct1"
                     /inference="alignment:Splign:2.1.0"
     exon            171..367
                     /gene="Cyc1"
                     /gene_synonym="2610002H19Rik; Cyct1"
                     /inference="alignment:Splign:2.1.0"
     exon            368..494
                     /gene="Cyc1"
                     /gene_synonym="2610002H19Rik; Cyct1"
                     /inference="alignment:Splign:2.1.0"
     exon            495..652
                     /gene="Cyc1"
                     /gene_synonym="2610002H19Rik; Cyct1"
                     /inference="alignment:Splign:2.1.0"
     exon            653..813
                     /gene="Cyc1"
                     /gene_synonym="2610002H19Rik; Cyct1"
                     /inference="alignment:Splign:2.1.0"
     exon            814..914
                     /gene="Cyc1"
                     /gene_synonym="2610002H19Rik; Cyct1"
                     /inference="alignment:Splign:2.1.0"
     exon            915..1520
                     /gene="Cyc1"
                     /gene_synonym="2610002H19Rik; Cyct1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1173..1178
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cyc1"
                     /gene_synonym="2610002H19Rik; Cyct1"
                     /note="hexamer: AATAAA"
     polyA_site      1195
                     /gene="Cyc1"
                     /gene_synonym="2610002H19Rik; Cyct1"
                     /note="major polyA site"
     regulatory      1216..1221
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cyc1"
                     /gene_synonym="2610002H19Rik; Cyct1"
                     /note="hexamer: ACTAAA"
     polyA_site      1238
                     /gene="Cyc1"
                     /gene_synonym="2610002H19Rik; Cyct1"
ORIGIN      
        1 aggggccgac gggaacggcg gccgcactaa agggggccga catggcggcg gcggcggctt
       61 cgcttcgccg gacggtactg ggcccgcggg gcgtggggct tccaggtgca agtgctccgg
      121 gtctgctggg cggcgcgcgg tcccggcagc ttccattgcg gacaccgcag gcagtgtcct
      181 tgtcctcgaa gtctggccct tctcgaggcc gaaaggtgat gctgtcagcg ttgggcatgc
      241 tggccgcggg gggtgcaggg ctagctgtgg cccttcattc tgccgtgagt gccagtgacc
      301 tggagctgca cccccccagc tacccatggt ctcatcgtgg cctcctctcc tccttggacc
      361 acaccagcat tcggaggggt ttccaggtat acaagcaggt gtgctcttcc tgccacagca
      421 tggattatgt ggcgtaccgc cacctggtgg gagtgtgcta cacggaggaa gaagccaagg
      481 cgctggctga ggaggtggag gtccaggatg gccctaatga tgatggggag atgttcatgc
      541 ggccagggaa gttgtctgac tattttccaa aaccataccc taaccctgag gctgcaagag
      601 ctgctaacaa tggagcttta ccccctgacc tcagctacat cgttcgagct aggcatggtg
      661 gtgaggacta cgtattttcc ctgctcactg gctactgtga gccccccact ggggtgtcat
      721 tgcgagaagg cctctatttc aacccttact ttcccggcca ggccattggc atggctcctc
      781 ccatctacac agaagtcttg gagtatgatg atggcacccc agctaccatg tcacaagtag
      841 ctaaggatgt cgccaccttc cttcgctggg catcagaacc agagcatgac catcgaaaac
      901 gcatgggtct caagatgttg ttgatgatgg gcctgctgct gcccctgacc tatgccatga
      961 agcggcataa gtggtcagtc ctgaagagtc gaaagctggc ttatcggcca cccaagtgac
     1021 cctgttcagt atctgcttgt catcttgcca gaacaagctc tcagcagccc aggaacagtc
     1081 catggccttc tcaggcctgg cccttttcat cagatacaag ggccaggaga ccagactctt
     1141 gcttctgatc ttccttcagc cctcagtgtg ggaataaatt aagtttctca acatacacat
     1201 tttagctggt caatgactaa aacatttttt cagtggaacc ctggaaccca tatttctcca
     1261 cattattgtt tcctgtactg cccagtatct gggagttatt gatatgcacc agaatgcaaa
     1321 acctggcagc actgtttgca tgggagagat ggctcagtgg ttaagagcac tggctgcttt
     1381 tccagaggac ctgggttcag ttcccagcac tcaacatggt ggctcaaaac catctgtctc
     1441 cagtcgcaag ggctctaaca ccctcttttg gccttcaagg cactgcatga atgtaataca
     1501 aagctgtccg tgtaggtaaa aaaaaaaaaa aaaa
//
