LOCUS       NM_001045525            3201 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus cytochrome b5 domain containing 1 (Cyb5d1), mRNA.
ACCESSION   NM_001045525 XM_001004435 XM_001004438 XM_282990 XM_908732
VERSION     NM_001045525.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3201)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3201)
  AUTHORS   Sundberg,J.P., Dadras,S.S., Silva,K.A., Kennedy,V.E., Garland,G.,
            Murray,S.A., Sundberg,B.A., Schofield,P.N. and Pratt,C.H.
  TITLE     Systematic screening for skin, hair, and nail abnormalities in a
            large-scale knockout mouse program
  JOURNAL   PLoS One 12 (7), e0180682 (2017)
   PUBMED   28700664
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3201)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   4  (bases 1 to 3201)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 3201)
  AUTHORS   McClintock,T.S., Glasser,C.E., Bose,S.C. and Bergman,D.A.
  TITLE     Tissue expression patterns identify mouse cilia genes
  JOURNAL   Physiol Genomics 32 (2), 198-206 (2008)
   PUBMED   17971504
  REMARK    GeneRIF: Cyb5d1 is most abundantly expressed in tissues rich in
            highly ciliated cells, such as olfactory sensory neurons, and is
            predicted to be important to cilia.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL596125.27.
            
            On Aug 24, 2018 this sequence version replaced NM_001045525.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660817.163579.1,
                                           SRR1660815.28738.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN01164141
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-213               AL596125.27        52473-52685         c
            214-290             AL596125.27        52311-52387         c
            291-509             AL596125.27        51967-52185         c
            510-3201            AL596125.27        48516-51207         c
FEATURES             Location/Qualifiers
     source          1..3201
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 42.59 cM"
     gene            1..3201
                     /gene="Cyb5d1"
                     /gene_synonym="Gm740"
                     /note="cytochrome b5 domain containing 1"
                     /db_xref="GeneID:327951"
                     /db_xref="MGI:MGI:2685586"
     exon            1..213
                     /gene="Cyb5d1"
                     /gene_synonym="Gm740"
                     /inference="alignment:Splign:2.1.0"
     CDS             54..740
                     /gene="Cyb5d1"
                     /gene_synonym="Gm740"
                     /codon_start=1
                     /product="cytochrome b5 domain-containing protein 1"
                     /protein_id="NP_001038990.1"
                     /db_xref="CCDS:CCDS24892.1"
                     /db_xref="GeneID:327951"
                     /db_xref="MGI:MGI:2685586"
                     /translation="MPRRGLVAGPDLDNFQRRYFTPSEVAEHNQLEDLWVSYLGFVYN
                     LTPLVEEFKGDLLLKPILEVAGQDISHWFDPQTRDIRKHIDPLTGCMRYRTPRGRFVH
                     IPPPLPRSDWANDFGVPWWKGANYQVGRLSARTRNIRIINTLATQEHTLQVGAQESMW
                     EILHRYLPYNAHAASYTWKYDGKNLNMDQTLEENGIRDEEEEFDYLNMDGKLHTPAIL
                     LYFNDDLTEL"
     exon            214..290
                     /gene="Cyb5d1"
                     /gene_synonym="Gm740"
                     /inference="alignment:Splign:2.1.0"
     exon            291..509
                     /gene="Cyb5d1"
                     /gene_synonym="Gm740"
                     /inference="alignment:Splign:2.1.0"
     exon            510..3201
                     /gene="Cyb5d1"
                     /gene_synonym="Gm740"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      3044
                     /gene="Cyb5d1"
                     /gene_synonym="Gm740"
                     /note="major polyA site"
ORIGIN      
        1 ggaggagcga gaaggtagct gagggagcct gtgcctcttg tagaccagga gccatgccgc
       61 gccggggcct agtagccggg ccagacttgg ataattttca acgtcggtat ttcacgccgt
      121 cagaagtagc ggaacacaac cagctcgagg acctatgggt gtcttacctg ggatttgttt
      181 acaatctaac accgcttgtc gaggaattca aaggggacct actgttgaaa cccatcctgg
      241 aggtcgcagg ccaggacata agtcactggt ttgatccaca gactagagac attcgcaagc
      301 atatagatcc actcactggt tgcatgagat accgtacccc gcggggccgc ttcgtacata
      361 tcccgccgcc actgccccgt tcagattggg ccaatgattt cggagtaccc tggtggaagg
      421 gggcaaatta ccaggtggga cgactgtctg ctcggacccg gaacatccgt attattaaca
      481 ctcttgcaac gcaggagcac acactgcagg tgggggctca ggaatcaatg tgggaaatcc
      541 tacaccgcta tctcccctat aatgcacatg ctgccagcta cacatggaaa tacgatggga
      601 agaatttgaa catggatcaa accctggaag aaaacgggat ccgggatgag gaagaagagt
      661 ttgactatct taacatggat ggtaaacttc acacacctgc aatactgctc tacttcaatg
      721 atgacctcac agagctctag gaaaggagat gtgcgtgtag actcaagatg ttggagtttg
      781 cctctttctg tgccttgagg gaaagaggtg tgggtctgtg gggcctggcc tacacctctg
      841 ttcccttctg agaatcagtc cgtggttctt gggcctttct gacatgcaag ggccttatcc
      901 ctggctcctt tgttcatggg tgatttgctc aaagagtatt agaggggtcc tagaaagaat
      961 ccctgtaaga gagctagagt ctctcaggaa tatgaggagg aagtaaggct caggcaaaac
     1021 tttttagtag ttagagacac agtgacgaag ggatggaaga acttttttgg caaaggtgag
     1081 aatgtgatgt aggaaggtga gatttacaaa gacaggattt ggaaattagc atcaccaatc
     1141 ataggtgggt ggctgacttc ttctctaaag gtctttacta gttggtgccc caggaaacgt
     1201 gaatgcagtt aatttaggat tgagattttg ctggagtttt acactgttca actcagctat
     1261 cctataaggt gactacatta ttcttaatta agactaatta tctatttcac agataattcc
     1321 ttaggaattt cccaaggttc tgtagcacaa gtgcacattg tcagttacgg cagagccaca
     1381 gtgcccaagc ctgccgagct ctgaaagtca ggcattttcc agtgtaaagg agcatcctca
     1441 gtagccttgc ctagtgctcg cgcatttccg acggctgctc tcaaaccctg tgtttggaat
     1501 gtgagcttgt cctaggcttg ttgcctgatg gggatatgtc agcctattgt gtactcaata
     1561 tttgttgtgt ttgaagggag ttaagagagt actctagaga caaaggcagg gaaggctaaa
     1621 tttcagccaa gcactggcaa ctgaggctac ttccttgttg atatcatagg atttctgact
     1681 gtttgggtgc aagaagatag gtatttcctg actctatgaa aaaccagaat ggagaaaggg
     1741 cctgtagctc aagacattgt agtgagggac ccacaaatgg gtaccttttt ttttccagta
     1801 ggccttgcca ctaacagaca acaaggaaga cagttggatt tgtcaaatgg tgaccctaaa
     1861 agaggtttgt tggggtcaga agaggggagc taagagaggc acacagctct catggtgact
     1921 gacttcatct ggttcccttt atccctaaca gaggaaggga attaagacta acagacaaat
     1981 agtgccaggc gtggtggctt taatcccagc accggggagc agagacaggt ggatttcatg
     2041 atttccaggc cagcctggcc tacagaacaa atgccaggac agccagggct acacagagaa
     2101 aacctgtctc aaaacaaaac caaaacaaca acatagtaac tggtaagtga acatccctgc
     2161 agcagccaca ggcaagtaag agtcaaggag cttgcatctt cccagtggtg gcctgggacg
     2221 cagggtgcgg tgccacgacc tccatgagac actgggtggg acacactgtc ttctgagaag
     2281 gtgactgtag gaagctgagc tgaggtgggg ctcaaactcc ggatttcagc gatttcttaa
     2341 tctgctgatg ctgaagtcgt tcacttagtc ccatgcaacc taagagtcca taaattgttt
     2401 ggatccatca atcgtgatat ttagtaagct cataaatgat cttatttaaa ctatttgaga
     2461 gccaaagccg tttcttccat gacatcctga gggaatgctc tggggtgtgc tcatttgacc
     2521 aagcttgtct cttttccagg acatcccact tgtagattat tttcctggga tggggtgggg
     2581 gtgtgtctca tgtcgggggt gtgtgactca ttatgtagcc ctggctcgcc aggactcaga
     2641 ggtcacttgc ctgttcacaa cttcttgtta gacacacact cctttccctg tatacccaag
     2701 cactcatcag ctccatctct ttggaatccg tccttttgtc taacagaata accatctttg
     2761 gtactgggaa acttcctgat gcccattttc tacttctgcc ttcacaaact taagtatctt
     2821 actttctgcc tcggatcttc agtgggtttc tcgtgctttt ggaataaagc cctaaattca
     2881 agaagccttg cgcaagtcag gccctgcctt cctcgccccc tcacagtcct tgtcctgcaa
     2941 gccgtgaggt ctcctcctgc ctcagttagc agagaagctg ttctcagccc accacaccct
     3001 tctgctttgc accttgagaa tcctaactag tcagtttttt ttctttgtct tttttggccc
     3061 cactttagca gtatgcattt tctctatgtt cttattatca ctttaaaact gtgtagacag
     3121 agccgggcag tggtggagca cgcctttaat cccagcactc aggaggcaga ggcaggcaga
     3181 tttctgagtt caaggccagc c
//
