LOCUS       NM_019568               1848 bp    mRNA    linear   ROD 25-FEB-2025
DEFINITION  Mus musculus C-X-C motif chemokine ligand 14 (Cxcl14), mRNA.
ACCESSION   NM_019568 XM_985110
VERSION     NM_019568.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1848)
  AUTHORS   Jasmine, Baraiya,D.H., Kavya,T.T., Mandal,A., Chakraborty,S.,
            Sathish,N., Francis,C.M.R. and Binoy Joseph,D.
  TITLE     Epithelial and mesenchymal compartments of the developing bladder
            and urethra display spatially distinct gene expression patterns
  JOURNAL   Dev Biol 520, 155-170 (2025)
   PUBMED   39798644
REFERENCE   2  (bases 1 to 1848)
  AUTHORS   Iannone,A.F., Akgul,G., Zhang,R., Wacks,S., Hussein,N.,
            Macias,C.G., Donatelle,A., Bauriedel,J.M.J., Wright,C., Abramov,D.,
            Johnson,M.A., Govek,E.E., Burre,J., Milner,T.A. and De Marco
            Garcia,N.V.
  TITLE     The chemokine Cxcl14 regulates interneuron differentiation in layer
            I of the somatosensory cortex
  JOURNAL   Cell Rep 43 (8), 114531 (2024)
   PUBMED   39058591
REFERENCE   3  (bases 1 to 1848)
  AUTHORS   Zhang,T., Zhao,C., Li,Y., Wu,J., Wang,F., Yu,J., Wang,Z., Gao,Y.,
            Zhao,L., Liu,Y., Yan,Y., Li,X., Gao,H., Hu,Z., Cui,B. and Li,K.
  TITLE     FGD5 in basal cells induces CXCL14 secretion that initiates a
            feedback loop to promote murine mammary epithelial growth and
            differentiation
  JOURNAL   Dev Cell 59 (16), 2085-2100 (2024)
   PUBMED   38821057
  REMARK    GeneRIF: FGD5 in basal cells induces CXCL14 secretion that
            initiates a feedback loop to promote murine mammary epithelial
            growth and differentiation.
REFERENCE   4  (bases 1 to 1848)
  AUTHORS   Carabana,C., Sun,W., Veludo Ramos,C., Huyghe,M., Perkins,M.,
            Maillot,A., Journot,R., Hartani,F., Faraldo,M.M., Lloyd-Lewis,B.
            and Fre,S.
  TITLE     Spatially distinct epithelial and mesenchymal cell subsets along
            progressive lineage restriction in the branching embryonic mammary
            gland
  JOURNAL   EMBO J 43 (12), 2308-2336 (2024)
   PUBMED   38760574
REFERENCE   5  (bases 1 to 1848)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   6  (bases 1 to 1848)
  AUTHORS   Bailey,P.J., Klos,J.M., Andersson,E., Karlen,M., Kallstrom,M.,
            Ponjavic,J., Muhr,J., Lenhard,B., Sandelin,A. and Ericson,J.
  TITLE     A global genomic transcriptional code associated with CNS-expressed
            genes
  JOURNAL   Exp Cell Res 312 (16), 3108-3119 (2006)
   PUBMED   16919269
REFERENCE   7  (bases 1 to 1848)
  CONSRTM   IUIS/WHO Subcommittee on Chemokine Nomenclature
  TITLE     Chemokine/chemokine receptor nomenclature
  JOURNAL   J Immunol Methods 262 (1-2), 1-3 (2002)
   PUBMED   12080938
REFERENCE   8  (bases 1 to 1848)
  AUTHORS   Cao,X., Zhang,W., Wan,T., He,L., Chen,T., Yuan,Z., Ma,S., Yu,Y. and
            Chen,G.
  TITLE     Molecular cloning and characterization of a novel CXC chemokine
            macrophage inflammatory protein-2 gamma chemoattractant for human
            neutrophils and dendritic cells
  JOURNAL   J Immunol 165 (5), 2588-2595 (2000)
   PUBMED   10946286
REFERENCE   9  (bases 1 to 1848)
  AUTHORS   Sleeman,M.A., Fraser,J.K., Murison,J.G., Kelly,S.L.,
            Prestidge,R.L., Palmer,D.J., Watson,J.D. and Kumble,K.D.
  TITLE     B cell- and monocyte-activating chemokine (BMAC), a novel non-ELR
            alpha-chemokine
  JOURNAL   Int Immunol 12 (5), 677-689 (2000)
   PUBMED   10784614
REFERENCE   10 (bases 1 to 1848)
  AUTHORS   Hromas,R., Broxmeyer,H.E., Kim,C., Nakshatri,H., Christopherson,K.
            2nd, Azam,M. and Hou,Y.H.
  TITLE     Cloning of BRAK, a novel divergent CXC chemokine preferentially
            expressed in normal versus malignant cells
  JOURNAL   Biochem Biophys Res Commun 255 (3), 703-706 (1999)
   PUBMED   10049774
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AU035952.1, BI133967.1, AK076112.1 and BC079661.1.
            
            On Dec 14, 2006 this sequence version replaced NM_019568.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF192557.1, AK004615.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849385
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-63                AU035952.1         1-63
            64-64               BI133967.1         335-335             c
            65-160              AU035952.1         65-160
            161-1823            AK076112.1         3-1665
            1824-1848           BC079661.1         1464-1488
FEATURES             Location/Qualifiers
     source          1..1848
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 30.06 cM"
     gene            1..1848
                     /gene="Cxcl14"
                     /gene_synonym="1110031L23Rik; 1200006I23Rik; BMAC;
                     bolekine; BRAK; Kec; KS1; MIP-2g; MIP2gamma; NJAC; Scyb14"
                     /note="C-X-C motif chemokine ligand 14"
                     /db_xref="GeneID:57266"
                     /db_xref="MGI:MGI:1888514"
     exon            1..442
                     /gene="Cxcl14"
                     /gene_synonym="1110031L23Rik; 1200006I23Rik; BMAC;
                     bolekine; BRAK; Kec; KS1; MIP-2g; MIP2gamma; NJAC; Scyb14"
                     /inference="alignment:Splign:2.1.0"
     CDS             379..678
                     /gene="Cxcl14"
                     /gene_synonym="1110031L23Rik; 1200006I23Rik; BMAC;
                     bolekine; BRAK; Kec; KS1; MIP-2g; MIP2gamma; NJAC; Scyb14"
                     /note="kidney-expressed chemokine CXC; musculus CXC
                     chemokine MIP-2gamma; C-X-C motif chemokine 14; chemokine
                     BRAK; small-inducible cytokine B14; B-cell and
                     monocyte-activating chemokine; small inducible cytokine
                     subfamily B (Cys-X-Cys), member 14; chemokine (C-X-C
                     motif) ligand 14"
                     /codon_start=1
                     /product="C-X-C motif chemokine 14 precursor"
                     /protein_id="NP_062514.2"
                     /db_xref="CCDS:CCDS36679.1"
                     /db_xref="GeneID:57266"
                     /db_xref="MGI:MGI:1888514"
                     /translation="MRLLAAALLLLLLALCASRVDGSKCKCSRKGPKIRYSDVKKLEM
                     KPKYPHCEEKMVIVTTKSMSRYRGQEHCLHPKLQSTKRFIKWYNAWNEKRRVYEE"
     exon            443..548
                     /gene="Cxcl14"
                     /gene_synonym="1110031L23Rik; 1200006I23Rik; BMAC;
                     bolekine; BRAK; Kec; KS1; MIP-2g; MIP2gamma; NJAC; Scyb14"
                     /inference="alignment:Splign:2.1.0"
     exon            549..662
                     /gene="Cxcl14"
                     /gene_synonym="1110031L23Rik; 1200006I23Rik; BMAC;
                     bolekine; BRAK; Kec; KS1; MIP-2g; MIP2gamma; NJAC; Scyb14"
                     /inference="alignment:Splign:2.1.0"
     exon            663..1827
                     /gene="Cxcl14"
                     /gene_synonym="1110031L23Rik; 1200006I23Rik; BMAC;
                     bolekine; BRAK; Kec; KS1; MIP-2g; MIP2gamma; NJAC; Scyb14"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1806..1811
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cxcl14"
                     /gene_synonym="1110031L23Rik; 1200006I23Rik; BMAC;
                     bolekine; BRAK; Kec; KS1; MIP-2g; MIP2gamma; NJAC; Scyb14"
                     /note="hexamer: AATATA"
     polyA_site      1827
                     /gene="Cxcl14"
                     /gene_synonym="1110031L23Rik; 1200006I23Rik; BMAC;
                     bolekine; BRAK; Kec; KS1; MIP-2g; MIP2gamma; NJAC; Scyb14"
                     /note="major polyA site"
ORIGIN      
        1 gcgatgggtc cggggcgggc ggcagggcgg tctgggagat ctcctccccc caccacattg
       61 agaaatctca gtgagtcacc gagtggttct gcatattaat gagctcgctc tccgagaggg
      121 caggagcgaa tttaaaagag gccagggtgg gcggagggaa gctgtgggga gatcgcagca
      181 cccagcgcca agcgcagcgc ggcaccgcga cagacggcag gagcacccat cgacgggcgt
      241 agctggagcg agccgagcag agcagagaga ggcgtgcttg aaaccgagaa ccaagccggg
      301 cggcatcccc cggccgccgc acgcacaggc cggcgccctc cttgcctccc tgctccccac
      361 cgcgcccctc cggccagcat gaggctcctg gcggccgcgc tgctcctgct gctcctggcg
      421 ctgtgcgcct cgcgcgtgga cgggtccaag tgtaagtgtt cccggaaggg gcccaagatc
      481 cgctacagcg acgtgaagaa gctggaaatg aagccaaagt acccacactg cgaggagaag
      541 atggttatcg tcaccaccaa gagcatgtcc aggtaccggg gccaggagca ctgcctgcac
      601 cctaagctgc agagcaccaa acgcttcatc aagtggtaca atgcctggaa cgagaagcgc
      661 agggtctacg aagaataggg tggacgatca tggaaagaaa aactccaggc cagttgagag
      721 acttcagcag aggactttgc agattaaaat aaaagccctt tctttctcac aagcataaga
      781 caaattatat attgctatga agctcttctt accagggtca gtttttacat tttatagctg
      841 tgtgtgaaag gcttccagat gtgagatcca gctcgcctgc gcaccagact tcattacaag
      901 tggctttttg ctgggcggtt ggcggggggc ggggggacct caagcctttc ctttttaaaa
      961 taaggggttt tgtatttgtc catatgtcac cacacatctg agctttataa gcgcctggga
     1021 ggaacagtga gcatggttga gaccgttcac agcactactg ctccgctcca ggcttacaaa
     1081 gcttccgctc agagagcctg gcggctctgc gcagctgcca caggctctcc tgggcttatg
     1141 actggtcaga gtttcagtgt gactccactg tggcccctgt tgcagggcaa ttgggagcag
     1201 gtccttctac atctgtgcct agaggaactc agtctactta ccagaaggag cttcatcccc
     1261 accccacccc cacccgcacc ccagctcatt cccctgtcac gaccaggcaa gtgatcctta
     1321 aaggagctgg gtctttttct tgcaaactga gggtttctga aaggtcccct gctttggtag
     1381 aagatgcttc tgaggcatcc aaagtcccca gcagtgtgag aaaatgatgc tcgatgttcg
     1441 ggaggacaag ggaagatgca ggattagatg caggacacac agccagagct acacatcctc
     1501 ttggcaatgg gagctccccc cccccaaagc tttgtttctt tccctcaccc caacagaaag
     1561 tgcactcccc ctcagtgaat acgcaaacag cactgttctc tgagttagga tgttaggacg
     1621 atcctgcgcc ctgccctctc ctgtgtacat attgccttca gtacccctcc cccaccccat
     1681 gccacacact gcccctcatt agaggccgca ctgtatggct gtgtatctgc tatgtaaatg
     1741 ctgagacccc tgagtgctgc atgcaggttt catgttcttt ctaagatgaa aagagaaagt
     1801 aataaaatat atttgaagtt accaaaaaaa aaaaaaaaaa aaaaaaaa
//
