LOCUS       NM_026186               3326 bp    mRNA    linear   ROD 31-MAY-2024
DEFINITION  Mus musculus CWC25 spliceosome-associated protein (Cwc25), mRNA.
ACCESSION   NM_026186
VERSION     NM_026186.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3326)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 3326)
  AUTHORS   Diez-Roux,G., Banfi,S., Sultan,M., Geffers,L., Anand,S., Rozado,D.,
            Magen,A., Canidio,E., Pagani,M., Peluso,I., Lin-Marq,N., Koch,M.,
            Bilio,M., Cantiello,I., Verde,R., De Masi,C., Bianchi,S.A.,
            Cicchini,J., Perroud,E., Mehmeti,S., Dagand,E., Schrinner,S.,
            Nurnberger,A., Schmidt,K., Metz,K., Zwingmann,C., Brieske,N.,
            Springer,C., Hernandez,A.M., Herzog,S., Grabbe,F., Sieverding,C.,
            Fischer,B., Schrader,K., Brockmeyer,M., Dettmer,S., Helbig,C.,
            Alunni,V., Battaini,M.A., Mura,C., Henrichsen,C.N.,
            Garcia-Lopez,R., Echevarria,D., Puelles,E., Garcia-Calero,E.,
            Kruse,S., Uhr,M., Kauck,C., Feng,G., Milyaev,N., Ong,C.K.,
            Kumar,L., Lam,M., Semple,C.A., Gyenesei,A., Mundlos,S., Radelof,U.,
            Lehrach,H., Sarmientos,P., Reymond,A., Davidson,D.R., Dolle,P.,
            Antonarakis,S.E., Yaspo,M.L., Martinez,S., Baldock,R.A., Eichele,G.
            and Ballabio,A.
  TITLE     A high-resolution anatomical atlas of the transcriptome in the
            mouse embryo
  JOURNAL   PLoS Biol 9 (1), e1000582 (2011)
   PUBMED   21267068
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY307671.1, AK004983.2, BC053447.1 and BY488530.1.
            
            On Oct 27, 2009 this sequence version replaced NM_026186.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660817.210350.1, AK004983.2
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164141, SAMN01164142
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-57                BY307671.1         1-57
            58-1071             AK004983.2         2-1015
            1072-3296           BC053447.1         226-2450
            3297-3326           BY488530.1         413-442
FEATURES             Location/Qualifiers
     source          1..3326
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 61.09 cM"
     gene            1..3326
                     /gene="Cwc25"
                     /gene_synonym="1300013D05Rik; Ccdc49"
                     /note="CWC25 spliceosome-associated protein"
                     /db_xref="GeneID:67480"
                     /db_xref="MGI:MGI:1914730"
     exon            1..189
                     /gene="Cwc25"
                     /gene_synonym="1300013D05Rik; Ccdc49"
                     /inference="alignment:Splign:2.1.0"
     CDS             172..1422
                     /gene="Cwc25"
                     /gene_synonym="1300013D05Rik; Ccdc49"
                     /note="coiled-coil domain-containing protein 49;
                     spliceosome-associated protein homolog CWC25; coiled-coil
                     domain containing 49; CWC25 spliceosome-associated protein
                     homolog"
                     /codon_start=1
                     /product="pre-mRNA-splicing factor CWC25 homolog"
                     /protein_id="NP_080462.2"
                     /db_xref="CCDS:CCDS25330.1"
                     /db_xref="GeneID:67480"
                     /db_xref="MGI:MGI:1914730"
                     /translation="MGGGDLNLKKSWHPQTLRNVEKVWKAEQKHEAERKKIEELQREL
                     REERAREEMQRYAEDVGAVKKKEEKLDWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEE
                     REAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLFIIRKKEEEKKREVLNNPVKM
                     KKIKELLQMSLEKKEKKKKKEKKKKHRKHKHRSSSSGGSSSEDEQSQARSQKKMANSF
                     PVLSKVPGYGLQVRDSDRNRGLQGSLGEQRAIKNNSRSRSSSPPRHASKKSTKEERPR
                     DRRSRSPSRRSRSPRPSKPHTSKVNRKERDSPSPKKEAYQRRHASGYTRKLSAEELER
                     KRQEMMENAKWREEERLNTLKRHAREDEREHRLERLDSRSGKFLHRMKLESASTSSLE
                     DRVKRNIHSLQRTSVALEKNFMRR"
     exon            190..362
                     /gene="Cwc25"
                     /gene_synonym="1300013D05Rik; Ccdc49"
                     /inference="alignment:Splign:2.1.0"
     exon            363..599
                     /gene="Cwc25"
                     /gene_synonym="1300013D05Rik; Ccdc49"
                     /inference="alignment:Splign:2.1.0"
     exon            600..669
                     /gene="Cwc25"
                     /gene_synonym="1300013D05Rik; Ccdc49"
                     /inference="alignment:Splign:2.1.0"
     exon            670..797
                     /gene="Cwc25"
                     /gene_synonym="1300013D05Rik; Ccdc49"
                     /inference="alignment:Splign:2.1.0"
     exon            798..861
                     /gene="Cwc25"
                     /gene_synonym="1300013D05Rik; Ccdc49"
                     /inference="alignment:Splign:2.1.0"
     exon            862..1055
                     /gene="Cwc25"
                     /gene_synonym="1300013D05Rik; Ccdc49"
                     /inference="alignment:Splign:2.1.0"
     exon            1056..1145
                     /gene="Cwc25"
                     /gene_synonym="1300013D05Rik; Ccdc49"
                     /inference="alignment:Splign:2.1.0"
     exon            1146..1307
                     /gene="Cwc25"
                     /gene_synonym="1300013D05Rik; Ccdc49"
                     /inference="alignment:Splign:2.1.0"
     exon            1308..3307
                     /gene="Cwc25"
                     /gene_synonym="1300013D05Rik; Ccdc49"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3139..3144
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cwc25"
                     /gene_synonym="1300013D05Rik; Ccdc49"
                     /note="hexamer: AATAAA"
     polyA_site      3164
                     /gene="Cwc25"
                     /gene_synonym="1300013D05Rik; Ccdc49"
                     /note="major polyA site"
     regulatory      3272..3277
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cwc25"
                     /gene_synonym="1300013D05Rik; Ccdc49"
                     /note="hexamer: AATAAA"
     polyA_site      3296
                     /gene="Cwc25"
                     /gene_synonym="1300013D05Rik; Ccdc49"
                     /note="major polyA site"
ORIGIN      
        1 agtcatatga caccaccccg gaagtgcgag ctagagcggg cggggaaaag ggcagctggt
       61 tcctgtaggg attaggtccc gagaggccgt ctctgaactg tttccctagg tttcctctct
      121 gccttcgctg aatctttcag gtccacagac tgaagaaccg tctccaccat catgggaggc
      181 ggagacctga acctgaagaa gagctggcac ccgcagaccc ttcgcaatgt ggagaaagtg
      241 tggaaggcgg agcagaagca tgaagcggag aggaagaaga ttgaggagtt gcagcgagag
      301 ctccgagagg agagagcgcg ggaggagatg cagcgctacg ctgaggatgt tggggctgtc
      361 aagaaaaaag aagaaaagtt ggattggatg taccaaggtc cgggtggcat ggtgaaccgt
      421 gatgagtact tgctggggcg ccccattgac aagtatgttt ttgagaagat ggaggagagg
      481 gaagctggct gctcttctga gacaggactc ctcccaggct caatctttgc cccgtcgggc
      541 gccaattccc ttcttgacat ggccagcaaa atccgggaag accctctctt catcataagg
      601 aagaaagagg aggagaaaaa aagagaagtg ctgaacaatc ctgtgaaaat gaagaaaatc
      661 aaagagctgt tgcaaatgag ccttgagaaa aaggagaaga agaagaagaa ggagaagaag
      721 aagaagcaca ggaagcacaa acacagaagc tccagcagcg gtggctccag cagcgaggat
      781 gagcagagcc aggcccggtc tcaaaagaag atggcaaatt cctttcctgt tttgtccaaa
      841 gtccctggat atggcttaca ggtgagggac tctgaccgga accgggggct gcagggttct
      901 ctgggtgaac agagggcgat aaagaacaat tcccggtcaa gaagctcctc accccccagg
      961 catgccagca agaagagcac caaggaagag aggccccggg acaggaggtc tcgatccccc
     1021 agcagaaggt cccggtcccc aaggcccagc aaaccgcata cctctaaggt aaacaggaaa
     1081 gagagagaca gcccatcacc taagaaggag gcctaccaga ggcggcatgc ttctgggtac
     1141 accagaaaac tctcagcaga ggaactagag cggaaacggc aggagatgat ggaaaatgcc
     1201 aagtggaggg aggaggagag gctcaacacc ctcaagaggc acgccaggga ggacgagcgg
     1261 gagcacaggc tggagaggtt ggactctcgg tccggcaagt tcctccaccg catgaagctg
     1321 gagagtgcgt cgacctcctc cctggaggac cgcgtgaagc gcaacatcca ttccctacag
     1381 cggacgtcgg tggccctgga gaagaacttc atgaggagat gagaaccagt ctcttgtact
     1441 gttttgcctg aattttccag ggaggctact gactccttaa aattctcttt ataagagttc
     1501 agatggcttc ctgtacagat gagaacccac cactgttcaa gtgccctttg tccactgact
     1561 cctgaaacac ttcacatccg ttaaacactg atgtgacctg aatcggggct cctcaggaac
     1621 tttggctgga tgtggatgca ctgtggggtt tgactgtgtt ttagtggctg ccactggacg
     1681 gcttggatgc ttgttatccc tcttccctcc cacctgaatg aatggatcag acttccagag
     1741 gcctctctta agagccaccc agatggacgg tgctcactgg gataaacaaa cattgacttt
     1801 atttagtaga ttatgtgaca ggatagccaa gcatcaggaa gagccaagaa ttgaagaagc
     1861 tggaagagaa aacagaacca aaagccctaa gtgaactgct acccacccgg gctttacgct
     1921 gtaatggtgt gatgtgtata tacaaatgta tagttctata tttgctttaa aaaagttagc
     1981 cttgggagaa cattttgttg gatgaccttg tcagaaaagt aacacagtag ttactggtaa
     2041 cagagggata ctgaccttct ttgtcatttg gacatgactt tgtcctctac aaatgtgtta
     2101 ggctacattt ataggtatgt actggcttca ggaaggacac acctgccaag ggacatacat
     2161 atcctcctct gttcctcggc atcctacagt gggcacccag tggggcagga atcaggaccc
     2221 atgttgtccg atgactcctg aaagaaaata cttgggaagc tttttgcttt ctggctaatt
     2281 tttatttgtt tgtttgttga ggcagggtct cttgtagctc aggctagctt tgattggacc
     2341 ggggagctga cggtgaccct gcactttagc tcctctgacc acacacagtt gctgctcctg
     2401 ccactgctgc tttgtggttt gtctgtgata cagggccctt gctggtccag ggcagcctga
     2461 tggtggctct cctgcctcag cctcctgagt gctggctgcg gttaggccat ccccatcctc
     2521 cagctgcctt tatcctgtaa taactaaaaa tctaagacaa gactcaaggg gccacaccca
     2581 tgtctttact gccattcctt tctctattct ttcaccagaa gccctcattt gtttgaccag
     2641 ggaacttcta ggtgcttttt aaacagacga cagattcacc ctagcggtag ctgaccttaa
     2701 actgtagatc tcctgtttta gtctctggag ctgtgattac agaccatctg gccctcagag
     2761 gtgctcttaa ttcatatatt aagccatttc gttgttctac cagttcctaa tttctcctaa
     2821 aatatgtttg gatttaagca ctaaaattcc agtcactgta attattgttg ttgttacttt
     2881 ttgagacagg gtttctcagt atagatagcc ctggctgtcc tggaactcac tctgtagacc
     2941 aggctggcct tgaactcaga aatctgcctg cctctgcctc ccaagtgctg ggattaaagg
     3001 catgcgccac cacgaccggc tggcactgta attcttaaaa ctcagtttct ccccagacaa
     3061 tataacatta ttcatttaat catctcatcc ttctgcccta tgttatagtt aattatggct
     3121 tttattttat tacttggtaa taaaggctac atttattttt gtaactgtgt agagcgatct
     3181 accacgtgcc tggtactgag tcttgatatc ccaagtgttg acctgtgatt tgtgtcggat
     3241 acagagaccc ttcgaccaag tggaattaca taataaacca tgggcagttt attcgagatt
     3301 tcttggaaaa aaaaaaaaaa aaaaaa
//
