LOCUS       NM_023153               1152 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus CWC15 spliceosome-associated protein (Cwc15), mRNA.
ACCESSION   NM_023153
VERSION     NM_023153.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1152)
  AUTHORS   Chanarat,S. and Strasser,K.
  TITLE     Splicing and beyond: the many faces of the Prp19 complex
  JOURNAL   Biochim Biophys Acta 1833 (10), 2126-2134 (2013)
   PUBMED   23742842
  REMARK    Review article
REFERENCE   2  (bases 1 to 1152)
  AUTHORS   O'Brien,K.P., Tapia-Paez,I., Stahle-Backdahl,M., Kedra,D. and
            Dumanski,J.P.
  TITLE     Characterization of five novel human genes in the 11q13-q22 region
  JOURNAL   Biochem Biophys Res Commun 273 (1), 90-94 (2000)
   PUBMED   10873569
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BQ840384.1, AK002864.1 and CT485607.8.
            
            On Oct 14, 2006 this sequence version replaced NM_023153.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK145249.1, BC004726.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-504               BQ840384.1         1-504
            505-1076            AK002864.1         444-1015
            1077-1152           CT485607.8         108744-108819
FEATURES             Location/Qualifiers
     source          1..1152
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 4.09 cM"
     gene            1..1152
                     /gene="Cwc15"
                     /gene_synonym="0610040D20Rik; 2900052N06Rik; c11orf5; Ed1;
                     mED1"
                     /note="CWC15 spliceosome-associated protein"
                     /db_xref="GeneID:66070"
                     /db_xref="MGI:MGI:1913320"
     exon            1..163
                     /gene="Cwc15"
                     /gene_synonym="0610040D20Rik; 2900052N06Rik; c11orf5; Ed1;
                     mED1"
                     /inference="alignment:Splign:2.1.0"
     exon            164..302
                     /gene="Cwc15"
                     /gene_synonym="0610040D20Rik; 2900052N06Rik; c11orf5; Ed1;
                     mED1"
                     /inference="alignment:Splign:2.1.0"
     CDS             172..861
                     /gene="Cwc15"
                     /gene_synonym="0610040D20Rik; 2900052N06Rik; c11orf5; Ed1;
                     mED1"
                     /note="protein CWC15 homolog; embryonic development factor
                     1; nucleoporin"
                     /codon_start=1
                     /product="spliceosome-associated protein CWC15 homolog"
                     /protein_id="NP_075642.1"
                     /db_xref="CCDS:CCDS22823.1"
                     /db_xref="GeneID:66070"
                     /db_xref="MGI:MGI:1913320"
                     /translation="MTTAARPTFEPARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYR
                     QTTQDAPEEVRNRDFRRELEERERAAARDKNRDRPTREHTTSSSVSKKPRLDQIPAAN
                     LDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRM
                     ENILSGNPLLNLTGPSQPQANFKVKRRWDDDVVFKNCAKGIDDQKKDKRFVNDTLRSE
                     FHKKFMEKYIK"
     exon            303..415
                     /gene="Cwc15"
                     /gene_synonym="0610040D20Rik; 2900052N06Rik; c11orf5; Ed1;
                     mED1"
                     /inference="alignment:Splign:2.1.0"
     exon            416..504
                     /gene="Cwc15"
                     /gene_synonym="0610040D20Rik; 2900052N06Rik; c11orf5; Ed1;
                     mED1"
                     /inference="alignment:Splign:2.1.0"
     exon            505..612
                     /gene="Cwc15"
                     /gene_synonym="0610040D20Rik; 2900052N06Rik; c11orf5; Ed1;
                     mED1"
                     /inference="alignment:Splign:2.1.0"
     exon            613..731
                     /gene="Cwc15"
                     /gene_synonym="0610040D20Rik; 2900052N06Rik; c11orf5; Ed1;
                     mED1"
                     /inference="alignment:Splign:2.1.0"
     exon            732..1152
                     /gene="Cwc15"
                     /gene_synonym="0610040D20Rik; 2900052N06Rik; c11orf5; Ed1;
                     mED1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      887..892
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cwc15"
                     /gene_synonym="0610040D20Rik; 2900052N06Rik; c11orf5; Ed1;
                     mED1"
                     /note="hexamer: ACTAAA"
     polyA_site      906
                     /gene="Cwc15"
                     /gene_synonym="0610040D20Rik; 2900052N06Rik; c11orf5; Ed1;
                     mED1"
                     /note="major polyA site"
     regulatory      1059..1064
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cwc15"
                     /gene_synonym="0610040D20Rik; 2900052N06Rik; c11orf5; Ed1;
                     mED1"
                     /note="hexamer: AATAAA"
     regulatory      1078..1083
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cwc15"
                     /gene_synonym="0610040D20Rik; 2900052N06Rik; c11orf5; Ed1;
                     mED1"
                     /note="hexamer: AATAAA"
     polyA_site      1079
                     /gene="Cwc15"
                     /gene_synonym="0610040D20Rik; 2900052N06Rik; c11orf5; Ed1;
                     mED1"
     polyA_site      1096
                     /gene="Cwc15"
                     /gene_synonym="0610040D20Rik; 2900052N06Rik; c11orf5; Ed1;
                     mED1"
ORIGIN      
        1 ttgcttccgg gtctcaaccg agcccctggt gtaaaaactg gaagctctgc attttgtttc
       61 cggtcttggg cctggcgccc ccggcgccga gatttctggg agctaagggt cgcattggtt
      121 catgagtgag tttcggaagg tgctgcgtag gacccccgcc agaactaaaa gatgacaaca
      181 gcagccaggc caacttttga acctgcaaga ggtgggagag gaaaaggaga aggggatttg
      241 agccagctct ccaagcagta ttcaagcaga gatcttccct ctcatacaaa gataaagtac
      301 agacaaacca cacaggatgc ccctgaagag gttcgaaacc gtgacttcag gagagaactg
      361 gaagagagag agagagctgc tgcaagggac aaaaacaggg accgcccaac tcgagagcat
      421 acaacttcct cttcagtgtc aaagaagccc cgcttagacc agattcctgc tgccaacctt
      481 gatgctgacg atcctctcac agacgaggaa gatgaagatt ttgaagagga gagcgatgac
      541 gatgatactg cagctcttct cgcagagcta gaaaagatca agaaggaaag agctgaagag
      601 caggccagga aggaacaaga acaaaaagca gaggaagaga gaattcgcat ggaaaacatt
      661 ctgagtggaa accctctcct aaacctcact ggcccgtccc agcctcaggc caacttcaag
      721 gttaaaagaa gatgggatga tgatgtcgtt tttaagaact gtgcaaaagg tatagatgac
      781 cagaagaaag acaaacgatt tgtaaatgat acactgcgat ctgaatttca caagaagttc
      841 atggagaaat atattaagta atatagtttt atgtgcttaa ttaaaaacta aactgttaag
      901 gatcaatttg actttttttt ttggtttctg ttctttccca gtgttaactt tctcagtctc
      961 tttcccttag tgtagtactt tattagataa tgggtttaga aatggatcta accaggcctt
     1021 agtttctttt taatatggga aacggggaat ctgcttgtaa taaatatttt taacctaaat
     1081 aaaccactgt ccccaacttt ttgctacaat ttatacagct tataaaaagt tgcataattt
     1141 cttttcaaaa tg
//
