LOCUS       NM_183315               1242 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus cortexin 1 (Ctxn1), mRNA.
ACCESSION   NM_183315
VERSION     NM_183315.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1242)
  AUTHORS   Yoo,D., Park,J., Lee,C., Song,I., Lee,Y.H., Yun,T., Lee,H.,
            Heguy,A., Han,J.Y., Dasen,J.S., Kim,H. and Baek,M.
  TITLE     Little skate genome provides insights into genetic programs
            essential for limb-based locomotion
  JOURNAL   Elife 11, e78345 (2022)
   PUBMED   36288084
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1242)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1242)
  AUTHORS   Li,C.L., Sathyamurthy,A., Oldenborg,A., Tank,D. and Ramanan,N.
  TITLE     SRF phosphorylation by glycogen synthase kinase-3 promotes axon
            growth in hippocampal neurons
  JOURNAL   J Neurosci 34 (11), 4027-4042 (2014)
   PUBMED   24623780
REFERENCE   4  (bases 1 to 1242)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   5  (bases 1 to 1242)
  AUTHORS   Horvath,D.H., Watson,J.B. and Travis,G.H.
  TITLE     Probable exclusion of the cortexin-encoding gene as a candidate for
            mouse neurological mutants: nervous, tottering and motor neuron
            degeneration
  JOURNAL   Gene 171 (2), 305-306 (1996)
   PUBMED   8666294
REFERENCE   6  (bases 1 to 1242)
  AUTHORS   Watson,J.B., Coulter,P.M. 2nd, Xia,Y.R. and Lusis,A.J.
  TITLE     Mouse chromosomal localization of the cortexin (Ctxn) gene
  JOURNAL   Genomics 22 (1), 251-252 (1994)
   PUBMED   7959786
REFERENCE   7  (bases 1 to 1242)
  AUTHORS   Coulter,P.M. 2nd, Bautista,E.A., Margulies,J.E. and Watson,J.B.
  TITLE     Identification of cortexin: a novel, neuron-specific, 82-residue
            membrane protein enriched in rodent cerebral cortex
  JOURNAL   J Neurochem 61 (2), 756-759 (1993)
   PUBMED   8336151
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DN176231.1, AK158759.1 and BF464653.1.
            
            On Oct 13, 2007 this sequence version replaced NM_183315.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DN176231.1, BC028881.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-107               DN176231.1         1-107
            108-1195            AK158759.1         2-1089
            1196-1242           BF464653.1         1-47                c
FEATURES             Location/Qualifiers
     source          1..1242
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 1.99 cM"
     gene            1..1242
                     /gene="Ctxn1"
                     /gene_synonym="Ctxn"
                     /note="cortexin 1"
                     /db_xref="GeneID:330695"
                     /db_xref="MGI:MGI:88566"
     exon            1..224
                     /gene="Ctxn1"
                     /gene_synonym="Ctxn"
                     /inference="alignment:Splign:2.1.0"
     exon            225..1226
                     /gene="Ctxn1"
                     /gene_synonym="Ctxn"
                     /inference="alignment:Splign:2.1.0"
     CDS             243..491
                     /gene="Ctxn1"
                     /gene_synonym="Ctxn"
                     /codon_start=1
                     /product="cortexin-1"
                     /protein_id="NP_899138.1"
                     /db_xref="CCDS:CCDS40211.1"
                     /db_xref="GeneID:330695"
                     /db_xref="MGI:MGI:88566"
                     /translation="MSSAWTLSPEPLPPSTGPPVGAGLDVEQRTVFAFVLCLLVVLVL
                     LMVRCVRILLDPYSRMPASSWTDHKEALERGQFDYALV"
     regulatory      1174..1179
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ctxn1"
                     /gene_synonym="Ctxn"
                     /note="hexamer: AATAAA"
     polyA_site      1203
                     /gene="Ctxn1"
                     /gene_synonym="Ctxn"
                     /note="major polyA site"
ORIGIN      
        1 cgtcgccatg ggaacagccg cggcggctgg gctggcgcgc ggctctcctt cctccctcgg
       61 tctccaccgc tccaggggcg ggtggggtgg gctgagccgg ggctgccaca gcctccgccg
      121 ctaccactgc cacccgggaa gaccagagca aagcagcgca cgagttccga gaaagagaga
      181 gagagagggg ctgcagggcg gccggtcccc gtctaggacc aaggagcgcg gcgatgtgag
      241 ctatgagttc ggcgtggaca ctatcaccgg agccgctgcc gccgtcgacg gggcccccgg
      301 tgggcgcggg cctggacgtc gagcaacgca cggtgttcgc cttcgtgctc tgcctgctcg
      361 tggtgttggt tctgttgatg gtgcgctgtg tgcgcatact gctagacccc tacagccgca
      421 tgcccgcctc gtcctggacc gaccacaagg aggcgctcga acgcgggcag ttcgactatg
      481 cgttggtgtg atggggaacc agtcggggca ggtccttagg gtcatccccg tggaggggtg
      541 ccaccagcct ggactgtgct cagggttatg cctagatgcc ctagctcgaa gttgagggcg
      601 ttcggagaag tccagtcctt acctacctta gctacccatc ttccttcctg gccaggccag
      661 aaccccacct ggtgccttta tctaccctgt ccccttctct ctacatactt atcctcattg
      721 ctgatccctc aacactgagt ccctggtgag tgaaggaccc cgcaccaacc tcagctttcc
      781 ccaactacca ggcatgctac attctttcct ggaaatgcgg acacctctta tctcttattt
      841 ctttgttatg gtcatcctca atttcagtgc actccttgag tcctggccct ggcaggcagg
      901 ctttcttcga ctcacattgg acgctgccta cctataatgc acggtacagt ttgcctcaga
      961 gacagaccca gaaaccccac catggctgct gcttgtgttg ataatatctg gcactttatg
     1021 tgcgggagta caagcaggct catccccttc ccagactcgg ccccagcaca ggttagagtg
     1081 cctttccttt gtcccacctc tcccatgtcc cccttgtccc catgcccttc ccttgccttt
     1141 cacacctccc cgcctctgaa ccgtggcaat tataataaaa gctattattg agtgcttact
     1201 gcatgtgaag cagattgctg agttaaaaaa aaaaaaaaaa aa
//
