LOCUS       NM_145582               2476 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus cytosolic thiouridylase subunit 1 (Ctu1), mRNA.
ACCESSION   NM_145582
VERSION     NM_145582.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2476)
  AUTHORS   Urbanek,M.E. and Zuo,J.
  TITLE     Genetic predisposition to tinnitus in the UK Biobank population
  JOURNAL   Sci Rep 11 (1), 18150 (2021)
   PUBMED   34518561
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2476)
  AUTHORS   Liu,X., Jiao,Y., Cao,Y., Deng,N., Ma,Y., Hasty,K.A., Kang,A.,
            Chen,H., Stuart,J.M. and Gu,W.
  TITLE     Decreased expression levels of Ifi genes is associated to the
            increased resistance to spontaneous arthritis disease in mice
            deficiency of IL-1RA
  JOURNAL   BMC Immunol 17 (1), 25 (2016)
   PUBMED   27480124
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC005752.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC005752.1, AK155284.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2476
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="NMRI"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 28.26 cM"
     gene            1..2476
                     /gene="Ctu1"
                     /gene_synonym="Atpbd3"
                     /note="cytosolic thiouridylase subunit 1"
                     /db_xref="GeneID:233189"
                     /db_xref="MGI:MGI:2385277"
     exon            1..45
                     /gene="Ctu1"
                     /gene_synonym="Atpbd3"
                     /inference="alignment:Splign:2.1.0"
     exon            46..588
                     /gene="Ctu1"
                     /gene_synonym="Atpbd3"
                     /inference="alignment:Splign:2.1.0"
     CDS             81..1343
                     /gene="Ctu1"
                     /gene_synonym="Atpbd3"
                     /note="cytoplasmic tRNA adenylyltransferase 1; ATP-binding
                     domain-containing protein 3; ATP binding domain 3;
                     cytosolic thiouridylase subunit 1 homolog"
                     /codon_start=1
                     /product="cytoplasmic tRNA 2-thiolation protein 1"
                     /protein_id="NP_663557.1"
                     /db_xref="CCDS:CCDS21179.1"
                     /db_xref="GeneID:233189"
                     /db_xref="MGI:MGI:2385277"
                     /translation="MPAPTCFSCHKTRAALRRPRSGQALCGSCFCAAFEAEVLHTVLA
                     GHLLPPGAVVAVGASGGKDSTVLAHVLRELAPRLGITLHLVAVDEGIGGYRDAALEAV
                     RSQAARWELPLTIVAYEDLFGGWTMDAVARSTAGSGRSRSCCTFCGVLRRRALEEGAR
                     LVGATHIVTGHNADDMAETVLMNFLRGDAGRLARGGVLGSTGEGCALPRCRPLQFASQ
                     KEVVLYAHFRHLRYFSEECVYAPEAFRGHARDLLKLLEAARPSAVLDLVHSAERLALA
                     PAAKPPPPGTCSRCGALASHKLCQACALLDGLNRGLPRLAIGKGRRVLQVEPPQPGNP
                     SLVTSDPVAPAGPCTCKQPKDKANPCGNGGDRAGATCVSQCDLSPGNGEDRAGATCVS
                     QRDLSLGNGGDRAGATCVSQCDLSPVAE"
     exon            589..2460
                     /gene="Ctu1"
                     /gene_synonym="Atpbd3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2441..2446
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ctu1"
                     /gene_synonym="Atpbd3"
                     /note="hexamer: AATAAA"
     polyA_site      2460
                     /gene="Ctu1"
                     /gene_synonym="Atpbd3"
                     /note="major polyA site"
ORIGIN      
        1 caggcttccg cgtggcaggc agagtactca gctcgttcca ctcagtgtag acctctcaga
       61 cgacccagtt ctctttcaag atgcccgccc cgacgtgctt ctcctgtcac aagacccgtg
      121 ctgccctccg tcgcccacgt tctgggcagg cgctgtgcgg ctcctgcttc tgtgctgcct
      181 ttgaggctga ggtgctacat acagtgcttg ccgggcacct gctgccgccg ggcgctgtag
      241 tggccgtggg tgcctctggt ggcaaggact ccacagtgct ggcacacgtg ctgcgtgagc
      301 ttgcgccccg cctgggcatc accctgcacc tggtggcggt ggatgagggc atcggcggct
      361 accgggacgc cgcgctggag gcagtgcgca gtcaggcggc gcgctgggag ctgccgctca
      421 ccatcgtggc ctacgaagat ctcttcgggg gctggacgat ggacgccgtg gcccgcagca
      481 ccgcaggctc cggccgcagt cgctcctgct gcaccttctg cggggtgctg cggaggcgcg
      541 cgctggagga gggtgcgcgc cttgtgggag ctacacatat tgtgacaggc cacaacgctg
      601 acgacatggc tgagacggtg ctcatgaact tcctgcgtgg tgatgctggg aggctggcga
      661 ggggtggggt gctgggctcc acgggcgagg ggtgcgcact tcccaggtgc cggcctctgc
      721 agtttgcctc gcagaaggag gtggtgctgt atgcgcactt ccgccatctc cgctactttt
      781 ccgaggagtg cgtgtatgcc cctgaggcct tccgtggtca tgcccgggac ctgcttaagc
      841 tcctggaggc ggccagacca tcagccgtgc tggacctcgt gcactcggca gagcgcctag
      901 ctctggctcc ggcagcaaag ccccctcctc caggcacctg ctcccgctgc ggagccctgg
      961 ccagccacaa gctctgccag gcctgtgccc tcctggatgg cctcaaccga ggcctgccgc
     1021 gcctggccat cggcaagggc cgccgtgtgc tgcaagttga gcctccacag cctgggaacc
     1081 caagcctagt caccagtgac cctgtggccc cagcaggacc ctgcacctgc aagcaaccga
     1141 aagataaagc caacccatgc ggcaatggag gggaccgggc aggagccacc tgtgtatcgc
     1201 agtgtgacct gagccccggg aatggagagg accgggcagg agccacctgt gtatcgcaga
     1261 gggacctgag ccttgggaat ggaggggacc gggcaggagc cacctgtgta tcgcagtgtg
     1321 acctgagccc cgtggcggag tgacctgagc tctgcactct acattgccct gtgtccgggg
     1381 aagtgattgt accccactgc cctgcaactg tggagtaatc tatacactgt gaagtgattt
     1441 cccttcagtg cacggcacct tgggactgac ctgtttccgt gtggagtggc tgtaccctgc
     1501 agagtcgctt gagccctgca gattatttaa agtgtccagt gccctgcaac ctgagccccg
     1561 tgtcctacct gtaccccatg gaaggatggg ccctgtagag caacatgaac cttgaagtat
     1621 agggcgctct aggcacagct accagctcta agagagaagg gaccaacacc catgcattcc
     1681 cgcacacctc tgtgggctca gagagccctg gccctccttt tctgttttcc caagtcaggt
     1741 aaacaaagtc acatgcgtac taggaatatt cacaatcgtc actatacccg tctcatccag
     1801 gcacagctct cgcacctacg ggaactggag aaagtttgtt ctgaaccagt tgggaccttc
     1861 catgggcggg tatgtgaatt gaggttgcct gggaaactgc cgtgggagca gttacacaaa
     1921 cgtttacagc cctaggacaa tagaaagtca ttaatcaaga cattggtcaa gtatgtcggt
     1981 gtgaactgca ggtagacagg ttatagcaaa gctgaaatcc cttctgtcag tctgaggaac
     2041 tatctgatga ctttcttagc ttgtgggtct ttggaagcca gtggtctgct gagctgatag
     2101 gttctgaacc aaatttgtag ttttcacatg gttgttgagt tagtgtcctg gctggccatt
     2161 ttttggtttt gttttgtcaa ctttacacag gctggggtca tctgagaaaa tgcttccata
     2221 agattggcct acaggcaagc ttgtggggca ttttctgatt gatgattgat gtggaagggc
     2281 tcagcccact gtgggcggtc cagtccctag gcaggtgatc ctggatacta taagaaagca
     2341 ggctgagtaa gccagtcagt agtagtgttc cctcatggcc tctgcctcag ttcctgctga
     2401 cttccctcag taatggagtg tgacctaaaa tgtaagttga aataaaactt tttctcgaaa
     2461 aaaaaaaaaa aaaaaa
//
