LOCUS       NM_080285               5980 bp    mRNA    linear   ROD 20-SEP-2024
DEFINITION  Mus musculus cortactin binding protein 2 (Cttnbp2), transcript
            variant 1, mRNA.
ACCESSION   NM_080285 XM_622569 XM_898143 XM_920330 XM_920340
VERSION     NM_080285.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5980)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5980)
  AUTHORS   Shih,P.Y., Fang,Y.L., Shankar,S., Lee,S.P., Hu,H.T., Chen,H.,
            Wang,T.F., Hsia,K.C. and Hsueh,Y.P.
  TITLE     Phase separation and zinc-induced transition modulate synaptic
            distribution and association of autism-linked CTTNBP2 and SHANK3
  JOURNAL   Nat Commun 13 (1), 2664 (2022)
   PUBMED   35562389
  REMARK    GeneRIF: Phase separation and zinc-induced transition modulate
            synaptic distribution and association of autism-linked CTTNBP2 and
            SHANK3.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5980)
  AUTHORS   Wu,T., Liang,Z., Zhang,Z., Liu,C., Zhang,L., Gu,Y., Peterson,K.L.,
            Evans,S.M., Fu,X.D. and Chen,J.
  TITLE     PRDM16 Is a Compact Myocardium-Enriched Transcription Factor
            Required to Maintain Compact Myocardial Cardiomyocyte Identity in
            Left Ventricle
  JOURNAL   Circulation 145 (8), 586-602 (2022)
   PUBMED   34915728
REFERENCE   4  (bases 1 to 5980)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5980)
  AUTHORS   Youlten,S.E., Kemp,J.P., Logan,J.G., Ghirardello,E.J., Sergio,C.M.,
            Dack,M.R.G., Guilfoyle,S.E., Leitch,V.D., Butterfield,N.C.,
            Komla-Ebri,D., Chai,R.C., Corr,A.P., Smith,J.T., Mohanty,S.T.,
            Morris,J.A., McDonald,M.M., Quinn,J.M.W., McGlade,A.R.,
            Bartonicek,N., Jansson,M., Hatzikotoulas,K., Irving,M.D.,
            Beleza-Meireles,A., Rivadeneira,F., Duncan,E., Richards,J.B.,
            Adams,D.J., Lelliott,C.J., Brink,R., Phan,T.G., Eisman,J.A.,
            Evans,D.M., Zeggini,E., Baldock,P.A., Bassett,J.H.D., Williams,G.R.
            and Croucher,P.I.
  TITLE     Osteocyte transcriptome mapping identifies a molecular landscape
            controlling skeletal homeostasis and susceptibility to skeletal
            disease
  JOURNAL   Nat Commun 12 (1), 2444 (2021)
   PUBMED   33953184
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5980)
  AUTHORS   Chen,Y.K., Chen,C.Y., Hu,H.T. and Hsueh,Y.P.
  TITLE     CTTNBP2, but not CTTNBP2NL, regulates dendritic spinogenesis and
            synaptic distribution of the striatin-PP2A complex
  JOURNAL   Mol Biol Cell 23 (22), 4383-4392 (2012)
   PUBMED   23015759
REFERENCE   7  (bases 1 to 5980)
  AUTHORS   Chen,Y.K. and Hsueh,Y.P.
  TITLE     Cortactin-binding protein 2 modulates the mobility of cortactin and
            regulates dendritic spine formation and maintenance
  JOURNAL   J Neurosci 32 (3), 1043-1055 (2012)
   PUBMED   22262902
REFERENCE   8  (bases 1 to 5980)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
REFERENCE   9  (bases 1 to 5980)
  AUTHORS   Cheung,J., Petek,E., Nakabayashi,K., Tsui,L.C., Vincent,J.B. and
            Scherer,S.W.
  TITLE     Identification of the human cortactin-binding protein-2 gene from
            the autism candidate region at 7q31
  JOURNAL   Genomics 78 (1-2), 7-11 (2001)
   PUBMED   11707066
REFERENCE   10 (bases 1 to 5980)
  AUTHORS   Ellsworth,R.E., Jamison,D.C., Touchman,J.W., Chissoe,S.L., Braden
            Maduro,V.V., Bouffard,G.G., Dietrich,N.L.,
            Beckstrom-Sternberg,S.M., Iyer,L.M., Weintraub,L.A., Cotton,M.,
            Courtney,L., Edwards,J., Maupin,R., Ozersky,P., Rohlfing,T.,
            Wohldmann,P., Miner,T., Kemp,K., Kramer,J., Korf,I., Pepin,K.,
            Antonacci-Fulton,L., Fulton,R.S., Minx,P., Hillier,L.W.,
            Wilson,R.K., Waterston,R.H., Miller,W. and Green,E.D.
  TITLE     Comparative genomic sequence analysis of the human and mouse cystic
            fibrosis transmembrane conductance regulator genes
  JOURNAL   Proc Natl Acad Sci U S A 97 (3), 1172-1177 (2000)
   PUBMED   10655503
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC027654.3 and AC158663.2.
            
            On Sep 20, 2017 this sequence version replaced NM_080285.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC141407.1, SRR9219380.49684.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-215               AC027654.3         171106-171320       c
            216-323             AC027654.3         158400-158507       c
            324-545             AC027654.3         104699-104920       c
            546-2172            AC158663.2         206372-207998       c
            2173-2376           AC158663.2         199991-200194       c
            2377-2476           AC158663.2         198588-198687       c
            2477-2627           AC158663.2         196383-196533       c
            2628-2879           AC158663.2         193318-193569       c
            2880-2997           AC158663.2         186734-186851       c
            2998-3273           AC158663.2         181034-181309       c
            3274-3369           AC158663.2         179008-179103       c
            3370-3449           AC158663.2         177736-177815       c
            3450-3536           AC158663.2         170070-170156       c
            3537-3636           AC158663.2         169885-169984       c
            3637-3789           AC158663.2         161635-161787       c
            3790-3977           AC158663.2         160580-160767       c
            3978-4156           AC158663.2         155298-155476       c
            4157-4362           AC158663.2         153520-153725       c
            4363-4539           AC158663.2         153015-153191       c
            4540-4603           AC158663.2         150919-150982       c
            4604-4736           AC158663.2         148489-148621       c
            4737-4835           AC158663.2         147076-147174       c
            4836-5980           AC158663.2         139024-140168       c
FEATURES             Location/Qualifiers
     source          1..5980
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 8.12 cM"
     gene            1..5980
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /note="cortactin binding protein 2"
                     /db_xref="GeneID:30785"
                     /db_xref="MGI:MGI:1353467"
     exon            1..215
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /inference="alignment:Splign:2.1.0"
     CDS             135..5081
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /note="CTTNBP2 intron retention form; cortactin-binding
                     protein 2 intron retention form"
                     /codon_start=1
                     /product="cortactin-binding protein 2"
                     /protein_id="NP_525024.1"
                     /db_xref="CCDS:CCDS39432.1"
                     /db_xref="GeneID:30785"
                     /db_xref="MGI:MGI:1353467"
                     /translation="MATDSASCEPDLSRTPGDTEGATAEAAKKEFDVDTLSKSELRML
                     LSVMEGELEARDLVIEALRARRKEVFIQERYGRFNLNDPFLALQRDYEAGPGDKEKPV
                     CTNPLSILEAVMAHCRKMQERMSAQLVAAESRQKKLEMEKLQLQALEQEHKKLAAHLE
                     EERGKNKHVVLMLVKECKQLSGKVVEEAQKLEEVMAQLEEEKKKTSELEEQLSAEKQR
                     SSGMEAQLEKQLSEFDTEREQLRAKLSREEAHTTDLKEEIDKMKKMMEQMKKGSDGKP
                     GLSLPRKTKDKRLASISVATEGPVTRSVACQTDVVTESTDPVKKLPLTVPIKPSTGSP
                     LVPTNTKGNVGPSALLIRPGIDRQSSHSDLGPSPPTALPSSANRIEENGPSTGNAPDL
                     SNSTPSTPSSTAPAAAQTPGTAPQNHSQAPTVHSLHSPCANTHPGLNPRIQAARFRFQ
                     GNANDPDQNGNNTQSPPSRDVSPTSRDNLVAKQLARNTVTQALSRFTSPQAGASSRLG
                     VSPGGDAGTCPPVGRTGLKTPGAARVDRGNPPPIPPKKPGLSQTPSPPHPQLRASNAG
                     AKVDNKIVASPPSTLPQGTKVVNEENVPKSSSPQLPPKPSIDLTVAPAGCPVSALATS
                     QVGAWPAGTPGLNQPACSDSSLVIPATVAFCSSINPVSASSRSPGASDSLLVAASGWS
                     PSLTPLLMSGGPAPLAGRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYS
                     AAKNGHTDCVRLLLNAEARVDAADKNGFTPLCVAAAQGHFECIELLTAYNANINHSAA
                     GGQTPLYLACKNGNKECIKLLLEAGTDRSIKTRDGWTPIHAAVDTGNVDSLKLLMYHR
                     VRAHGNSLSSEEPKSGLFSLNGGESPTGPSKPVVPADLINHADKEGWTAAHIAASKGF
                     KNCLEVLCRHGGLEPERRDKCNRTVHDVATDDCKHLLENLNALKIPLRISVGEIQPSN
                     DVSDDFECEHTICTLNIRKQTSWEDFSKAVSQALTNHFQAISSDGWWSLEDGTFNNAT
                     DSCIGLGTSSIRSIMLGSMPWSTGQSFSQSPWDFLKKKKVEQVLALLSGPQEGCLSSV
                     TYASMIPLQMLQNYLRLVEQYHNVIFHGPEGSLQDYIANQLALCMKYRQMAAGFPCEI
                     VRAEVDSGFSKEQLVDVFIRNACLIPVKQFPVKKKIIVILENLEKSSLSELLGDFLAP
                     LENRSTESPCTFQKGNGTSECYYFHENCFLVGTIAKACLQGSDLLVQQHFRWVQLRWD
                     CEPIQGLLQRFLRRKVVSKFRGQLPAPCDPVCKIVDWALSVWRQLNSCLARLGTPEAL
                     LGPKYFLSCPVVPGHAQATVKWMSKLWNAVIAPRVQEAILSRASMNKQPGTGQTASKK
                     YPSQGQQAVVRAALSILLNKAVLHGCPLPRAELDQQIADFKGGSFPLSIVSSYSKKKV
                     ESGAWRKVNTSPRKKPGHFSSPTWNKPDPKREGMRNKTIPHLNTNRNSSLSKQQSLEN
                     DLSVTLTLDHRLSLGSDDEADLVKELQSMCSSKSESDISKIADSRDDLRKFDSSRTNP
                     GTSAPLNLRTPVPQKEASPPSSRQTAECSNSKSKTEMGVSSVKSFLPVPRSKVAQCSQ
                     NTKRNSSSSNTRQLEINNNSKEENWTLDKHEQVEKPNK"
     exon            216..323
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /inference="alignment:Splign:2.1.0"
     exon            324..545
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /inference="alignment:Splign:2.1.0"
     exon            546..2172
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /inference="alignment:Splign:2.1.0"
     exon            2173..2376
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /inference="alignment:Splign:2.1.0"
     exon            2377..2476
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /inference="alignment:Splign:2.1.0"
     exon            2477..2627
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /inference="alignment:Splign:2.1.0"
     exon            2628..2879
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /inference="alignment:Splign:2.1.0"
     exon            2880..2997
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /inference="alignment:Splign:2.1.0"
     exon            2998..3273
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /inference="alignment:Splign:2.1.0"
     exon            3274..3369
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /inference="alignment:Splign:2.1.0"
     exon            3370..3449
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /inference="alignment:Splign:2.1.0"
     exon            3450..3536
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /inference="alignment:Splign:2.1.0"
     exon            3537..3636
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /inference="alignment:Splign:2.1.0"
     exon            3637..3789
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /inference="alignment:Splign:2.1.0"
     exon            3790..3977
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /inference="alignment:Splign:2.1.0"
     exon            3978..4156
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /inference="alignment:Splign:2.1.0"
     exon            4157..4362
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /inference="alignment:Splign:2.1.0"
     exon            4363..4539
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /inference="alignment:Splign:2.1.0"
     exon            4540..4603
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /inference="alignment:Splign:2.1.0"
     exon            4604..4736
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /inference="alignment:Splign:2.1.0"
     exon            4737..4835
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /inference="alignment:Splign:2.1.0"
     exon            4836..5980
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5739..5744
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /note="hexamer: AATAAA"
     polyA_site      5765
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /note="major polyA site"
     regulatory      5869..5874
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
                     /note="hexamer: AATAAA"
     polyA_site      5905
                     /gene="Cttnbp2"
                     /gene_synonym="3010022N24Rik; 4732477G22Rik; 6430526E05;
                     9130022E09Rik; Cortbp2; mKIAA1758; ORF4"
ORIGIN      
        1 gggagggggc ggccgagctc ccgggctgag agcgcggcgg ccacagccag cagcgggtta
       61 agtaccgccc gcgccgagag agctgaaccc cgccgccgct ccgagctcgc attcggatcc
      121 gctagagcag gaagatggcg acggacagcg cgagctgcga gcccgacttg tcccgcaccc
      181 cgggtgacac ggagggggcc acggcggagg cggcgaaaaa ggaatttgat gtggacacgc
      241 tcagcaaatc agagctgcgg atgctcctta gcgtgatgga aggtgaacta gaagccagag
      301 acctggtgat tgaggccctg agggctcgca ggaaggaggt gttcatccag gaacggtatg
      361 ggaggtttaa tctaaatgac cccttcctgg cacttcagag agactatgaa gcaggtcctg
      421 gtgacaaaga gaagccagtc tgcaccaatc cactctccat ccttgaagct gtcatggccc
      481 actgcagaaa aatgcaagaa aggatgtccg cacagctggt ggccgctgag agcagacaaa
      541 aaaagttgga gatggaaaag ctccagctcc aggcccttga acaggagcac aagaagctgg
      601 ctgcccacct ggaggaagag cggggcaaga acaagcacgt ggtcctgatg ctggtgaagg
      661 agtgtaagca gctctcgggc aaagtcgtgg aggaggccca gaagctggag gaagtcatgg
      721 cgcaactgga ggaggaaaag aaaaagacaa gtgagttaga agagcagctc tcagctgaga
      781 aacagagaag ctctggaatg gaagctcagt tggagaaaca gctctccgag tttgacacgg
      841 aacgggagca gctgcgcgcc aagctgagcc gagaggaagc acacaccacc gacctcaaag
      901 aggagataga caagatgaag aaaatgatgg agcaaatgaa gaagggaagt gatggcaagc
      961 ccggcctctc cctcccacgg aagacaaaag ataagcgcct ggcttccata tctgtggcaa
     1021 cagaagggcc tgtgacaagg tccgttgctt gccagacaga tgtagtgaca gaaagcactg
     1081 accctgtgaa gaagttgcct ttgactgtac ccataaagcc ttccacaggg agccccctag
     1141 ttcccacaaa cacaaaaggg aatgtgggcc ccagtgccct gctgattaga ccaggtattg
     1201 ataggcagtc ttcccacagt gacttgggtc cctctccacc tactgctcta ccttcaagtg
     1261 caaacagaat tgaggagaat ggaccaagca caggcaatgc ccctgatcta tcaaatagca
     1321 ccccctcaac tcctagtagc actgcccctg ccgctgctca gacaccaggc acagcacccc
     1381 agaaccactc acaagctcct actgtgcaca gtttacattc accatgtgcc aacactcatc
     1441 caggcctcaa cccacgcatc caagcagcta gattcagatt tcagggcaat gcaaatgacc
     1501 cagaccagaa tggaaataac actcaaagcc ctccctcgag agatgtctct cctacgagtc
     1561 gtgacaacct agtagccaag cagctagctc ggaatactgt gacccaagcg ctgtccagat
     1621 ttaccagccc tcaagcgggt gcttcttcaa gacttggagt atctccagga ggggacgctg
     1681 gcacctgccc tccagttggt cgaaccggtt taaagactcc cggggcagca agagttgaca
     1741 gaggaaatcc tcctcctatc cctcccaaaa agccagggct ctcccaaact ccttctccgc
     1801 cacaccccca actgagggcc tccaatgcag gggccaaagt tgataacaaa attgtggctt
     1861 cacctccctc tactttgcca caagggacca aggtagtaaa tgaggagaac gtccctaagt
     1921 cgtcctcccc tcagctgcca ccaaaaccgt ccatagattt aactgtggca cctgcaggct
     1981 gtcccgtttc ggccctggcc acgtctcagg tgggtgcctg gcctgctgga acccctggac
     2041 tgaaccaacc cgcatgttca gacagctccc ttgtcattcc cgccaccgtt gccttttgct
     2101 cttccataaa ccctgttagt gcctcatccc gtagccccgg tgcctcagac agcctcttgg
     2161 tagcagcatc aggctggtca ccctccctaa cccctttgct aatgagtggt ggtcctgccc
     2221 ccctggctgg caggcccacc cttcttcagc aagctgctgc ccagggaaat gtcactttat
     2281 tatcaatgct gcttaatgaa gaaggactgg acataaatta ctcctgcgaa gatggccatt
     2341 ctgccttgta ttctgctgct aagaatggac atacagactg tgtgcgattg ctgctgaatg
     2401 cagaagcccg agtcgacgct gctgataaaa atggcttcac acccttgtgc gtcgcagctg
     2461 ctcagggaca ttttgaatgt atagaattac taactgcata caatgccaac attaatcact
     2521 ctgctgctgg aggacagaca cctttgtact tggcctgtaa aaatggaaat aaggaatgta
     2581 tcaaactcct gctggaagct ggcactgacc ggagcataaa aaccagagat ggctggacgc
     2641 caattcacgc agctgtggac actggtaatg tggacagcct caagctcctg atgtaccata
     2701 gagtgcgagc ccatggaaac tctttgagtt cagaagagcc caagtcaggc ttgttcagct
     2761 tgaatggagg agagagccct acgggtccat ctaagcctgt ggttcctgca gacctaatta
     2821 accacgctga caaagaaggc tggactgctg cccacattgc tgcctccaaa ggtttcaaga
     2881 actgcctaga agtcttgtgt aggcatggag gactagagcc ggaaaggaga gacaagtgca
     2941 atcggactgt gcacgatgtt gccactgatg actgcaagca tttgctggag aatctgaatg
     3001 ctcttaaaat acccttaagg atttccgtgg gtgagattca accaagcaac gatgtttctg
     3061 acgactttga atgtgaacat acgatatgca ctttaaatat ccgcaaacag acatcatggg
     3121 aagatttttc caaagcagtg agtcaggctc tgacaaatca tttccaagcc atctcttctg
     3181 atggatggtg gagtctggaa gatgggacat ttaataatgc tactgactcc tgcatcggtc
     3241 ttggcaccag cagtatacga tccatcatgt taggaagtat gccgtggtca actggtcaga
     3301 gcttctccca gtccccgtgg gacttcttga aaaagaagaa ggtggagcag gtcctggcgc
     3361 tcttgtcagg tccccaagaa ggctgcctca gtagtgtgac ttacgcatcc atgatcccac
     3421 ttcagatgct gcagaactac ctcaggctgg ttgagcaata tcataatgtc attttccatg
     3481 gaccagaagg aagcttgcaa gactacatag caaatcagct tgccctctgc atgaagtaca
     3541 gacagatggc tgcaggattc ccctgtgaaa tagtgagagc cgaggtggat tcgggtttct
     3601 ccaaagagca gctagtagac gtgttcatca ggaatgcttg tctcatccca gtgaagcagt
     3661 tccctgttaa gaagaaaata atcgtcatct tggaaaattt ggaaaaatct tcattgtctg
     3721 agttactggg ggactttctg gcacctttgg aaaatcgcag cactgaaagc ccctgcactt
     3781 tccaaaaagg aaatggaaca tccgaatgct attatttcca tgagaactgc tttctggtgg
     3841 gaaccattgc caaagcctgt ctccagggct ctgacctgct ggtacagcaa cacttccgct
     3901 gggttcagct gcgctgggat tgcgagccca ttcaaggatt gcttcagagg ttcttacgaa
     3961 ggaaagtcgt cagcaagttc agaggtcagc tgcctgcacc ctgtgatcct gtatgtaaga
     4021 ttgtggactg ggctctgtct gtctggaggc agctcaactc ctgtctggcc cgcttgggta
     4081 caccagaagc acttcttgga ccaaagtatt tcctgtcgtg tccagtagtc ccgggacatg
     4141 cccaggcaac agtgaagtgg atgtctaagc tgtggaatgc tgtcattgct cccagagttc
     4201 aagaagcaat attgtcaaga gcctccatga acaaacaacc tggtactggg cagacagctt
     4261 ctaagaagta ccctagccaa ggacagcagg ctgtggtgag ggccgccctc agcattctgc
     4321 ttaataaagc ggttctgcat ggctgtcccc ttcccagggc agagctggat cagcagatcg
     4381 cagacttcaa agggggcagt tttcctctgt caatagtgtc aagttatagc aaaaagaaag
     4441 tggagagcgg cgcctggaga aaggtgaaca ccagtcctcg aaagaagcct gggcacttct
     4501 cctcacccac gtggaacaag ccagacccga agcgtgaagg tatgaggaac aagactatac
     4561 cacacctgaa tactaacagg aactcctctc tgtcgaagca acagtcctta gagaatgatc
     4621 tatctgtgac attgactttg gaccacagac tctctttggg ttcagatgat gaagcagatc
     4681 tggtcaaaga actccagagt atgtgttcca gcaaatctga gtctgatata agtaagattg
     4741 ctgattccag ggatgacttg aggaagtttg atagttcaag aaccaaccct gggacttcag
     4801 cacctcttaa cctgaggaca ccagtgccac agaaggaagc cagtcctccc agcagccgtc
     4861 aaactgccga atgcagcaac agtaaatcaa agactgagat gggtgtctca agcgttaaat
     4921 cttttcttcc tgttcctaga agcaaagtcg ctcagtgttc ccagaacacc aaaagaaaca
     4981 gcagcagcag caatacaagg caactagaaa tcaacaacaa ctccaaagaa gagaattgga
     5041 ccttagacaa acacgaacaa gtagaaaaac caaacaaata ggcctgccta caccacctac
     5101 tacaacatga tcacctaact tcttttgtat attccatgca gagaccaaga caaagaagat
     5161 gtaaataact tcaaatgaat aaaaccattt tttcctgtaa tataaaggag gcgtgcggga
     5221 ccactattca gctttttgta aagaatgtat ttataacctc acattttttt tcctgttact
     5281 tctataagac taaacttcga acccatgaag tgatggcaac tttccaagta gtttttataa
     5341 tagaaacctt gtaataattt taaccaagat gttcaggggt attaaagcag atgtttctgt
     5401 gtactgtata ttgctacctg tacatatgta catatatgta tatttatgga agttacatac
     5461 atgtgtacaa gattggtgta gatgaaatgt gccattttga atggagatga taatttttat
     5521 gttcatctga tggggaacaa tgcgaatggg gcaataacaa gacatttcta aacagttatt
     5581 ttccattaaa agccatacaa agtattttgc ctgttaaaat tctagtttta cattttgaat
     5641 cttttagtgg ttacattgcc atctggttgc atcatgtata tatatattta ctcttctgag
     5701 tttgcattta tgacttgtaa aatataaaat tatactgcaa taaaagtgtt atctttctta
     5761 caaaactttt gtacctaagt ggatataaaa gttatctgca caaagaaaga cgtcgattaa
     5821 atgaatttgg agttaacgcc ttcaatatat ttctaataac acactgataa taaaactaat
     5881 attttctaga agtgtgtctt ataaataaat ggtgaaatta ttgatccaat tcacagttaa
     5941 ggtactttga caccaaataa aattttgaat tagcaaagtt
//
