LOCUS       NM_021445               1323 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus cathepsin 6 (Cts6), mRNA.
ACCESSION   NM_021445
VERSION     NM_021445.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1323)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1323)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. PMID: 29144450]
REFERENCE   3  (bases 1 to 1323)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 1323)
  AUTHORS   Kim,J., Frey,W.D., He,H., Kim,H., Ekram,M.B., Bakshi,A., Faisal,M.,
            Perera,B.P., Ye,A. and Teruyama,R.
  TITLE     Peg3 mutational effects on reproduction and placenta-specific gene
            families
  JOURNAL   PLoS One 8 (12), e83359 (2013)
   PUBMED   24391757
  REMARK    Erratum:[PLoS One. 2014;9(1).
            doi:10.1371/annotation/8de03ec5-e62c-4135-87ee-4928475090a8]
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1323)
  AUTHORS   Knox,K. and Baker,J.C.
  TITLE     Genomic evolution of the placenta using co-option and duplication
            and divergence
  JOURNAL   Genome Res 18 (5), 695-705 (2008)
   PUBMED   18340042
REFERENCE   6  (bases 1 to 1323)
  AUTHORS   Deussing,J., Kouadio,M., Rehman,S., Werber,I., Schwinde,A. and
            Peters,C.
  TITLE     Identification and characterization of a dense cluster of
            placenta-specific cysteine peptidase genes and related genes on
            mouse chromosome 13
  JOURNAL   Genomics 79 (2), 225-240 (2002)
   PUBMED   11829493
REFERENCE   7  (bases 1 to 1323)
  AUTHORS   Nakajima,A., Kataoka,K., Takata,Y. and Huh,N.H.
  TITLE     Cathepsin-6, a novel cysteine proteinase showing homology with and
            co-localized expression with cathepsin J/P in the labyrinthine
            layer of mouse placenta
  JOURNAL   Biochem J 349 Pt 3 (Pt 3), 689-692 (2000)
   PUBMED   10903127
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF223401.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF223401.1, BC099455.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1323
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="ICR"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 32.67 cM"
     gene            1..1323
                     /gene="Cts6"
                     /gene_synonym="1600022N02Rik"
                     /note="cathepsin 6"
                     /db_xref="GeneID:58518"
                     /db_xref="MGI:MGI:1889619"
     exon            1..55
                     /gene="Cts6"
                     /gene_synonym="1600022N02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            56..190
                     /gene="Cts6"
                     /gene_synonym="1600022N02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            191..313
                     /gene="Cts6"
                     /gene_synonym="1600022N02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            314..463
                     /gene="Cts6"
                     /gene_synonym="1600022N02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            464..688
                     /gene="Cts6"
                     /gene_synonym="1600022N02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            689..851
                     /gene="Cts6"
                     /gene_synonym="1600022N02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            852..969
                     /gene="Cts6"
                     /gene_synonym="1600022N02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            970..1323
                     /gene="Cts6"
                     /gene_synonym="1600022N02Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aatttctgaa gagttcactc tgcagaacac actgaggcaa cagcaatcac cacaggtcgt
       61 gagaatgagt cctactttat ttttggccat cctgtgtttg ggagtgggct caggtgccct
      121 agcacttgat cccaatttga atgctgaatg gcatgattgg aagaaacagt atgaaaaatc
      181 atacaccatg gaggaagaag gactgaggag agcaatatgg gaagaaaaca tgagaatgat
      241 caaactgcac aactgggaga atagcctggg gaagaataac ttcaccttga aaatgaatga
      301 atttggtgac ctgactcctg aagaactcag aaaaatgatg aacaattttc caatctggag
      361 tcacaagaag agaaaaatca tcaggaagcg cgcagttggt gatgttctac ccaaatttgt
      421 ggactggaga aagaaaggct atgtgactcg agtacggaga cagaaatttt gtaattcctg
      481 ttgggctttt gctgtgaatg gtgccataga aggacagatg ttcaaaaaaa ctggcaaact
      541 cacccctctg agtgttcaga acctagtgga ctgtactaaa actcaaggaa atgatggctg
      601 ccaatggggt gatccataca ttgcctatga atatgttttg aataatggag gtctggaggc
      661 tgaggcaacc tatccatatg aaggaaaaga aggaccatgc aggtacaatc caaagaattc
      721 taaggctgaa atcacaggat ttgtgtccct cccagaaagc gaagatattc taatggaagc
      781 tgtagcaact attgggccca tctctgctgc agtggatgct tcctttaaca gattcagttt
      841 ctacgatgga ggtatttatc atcagccaaa ttgcagcaat aatactgtga atcatgcagt
      901 tctggtggtt ggctatggaa ctgagggaaa tgaaacagat ggcaataagt actggctaat
      961 caagaacagc tggggtagaa gatggggcat tggaggctac atgaagatta tcagagacca
     1021 gaacaaccac tgtggcattg ctacatatgc acattatccc attgtatgag cagtctgatg
     1081 cacacaggga agaatgtgag acagcatttc cacagtaatg tcatccactt caatgaccag
     1141 ccttcccttg ctgtgttaaa aagttgaacc ctagaagagc tctgttacta tttgaattct
     1201 tagaactttc aatgttttga cattatgagt caaaattgtt tctctcacta atgaatattc
     1261 atgattcctg tgataactct attctcactg ttaatgtttg tgcaaataaa gtacaataaa
     1321 act
//
