LOCUS       NM_054092               1381 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus cathepsin 3 (Cts3), transcript variant 2, mRNA.
ACCESSION   NM_054092
VERSION     NM_054092.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1381)
  AUTHORS   Kim J, Frey WD, He H, Kim H, Ekram MB, Bakshi A, Faisal M, Perera
            BP, Ye A and Teruyama R.
  TITLE     Peg3 mutational effects on reproduction and placenta-specific gene
            families
  JOURNAL   PLoS One 8 (12), e83359 (2013)
   PUBMED   24391757
  REMARK    Erratum:[PLoS One. 2014;9(1).
            doi:10.1371/annotation/8de03ec5-e62c-4135-87ee-4928475090a8]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1381)
  AUTHORS   Labied S, Blacher S, Carmeliet P, Noel A, Frankenne F, Foidart JM
            and Munaut C.
  TITLE     Transient reduction of placental angiogenesis in PAI-1-deficient
            mice
  JOURNAL   Physiol Genomics 43 (4), 188-198 (2011)
   PUBMED   21119013
REFERENCE   3  (bases 1 to 1381)
  AUTHORS   Deussing J, Kouadio M, Rehman S, Werber I, Schwinde A and Peters C.
  TITLE     Identification and characterization of a dense cluster of
            placenta-specific cysteine peptidase genes and related genes on
            mouse chromosome 13
  JOURNAL   Genomics 79 (2), 225-240 (2002)
   PUBMED   11829493
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY035057.1, AK005389.1 and AY034574.1.
            
            On Jul 8, 2011 this sequence version replaced NM_054092.1.
            
            Transcript Variant: This variant (2) is alternatively spliced in
            the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same
            protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC099388.1, AK005389.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 BY035057.1         1-2
            3-477               AK005389.1         1-475
            478-478             AY034574.1         492-492
            479-1366            AK005389.1         477-1364
            1367-1381           AY034574.1         1381-1395
FEATURES             Location/Qualifiers
     source          1..1381
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 32.74 cM"
     gene            1..1381
                     /gene="Cts3"
                     /gene_synonym="1600000I23Rik"
                     /note="cathepsin 3"
                     /db_xref="GeneID:117066"
                     /db_xref="MGI:MGI:2151929"
     exon            1..90
                     /gene="Cts3"
                     /gene_synonym="1600000I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            91..218
                     /gene="Cts3"
                     /gene_synonym="1600000I23Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             93..1091
                     /gene="Cts3"
                     /gene_synonym="1600000I23Rik"
                     /codon_start=1
                     /product="cathepsin 3 precursor"
                     /protein_id="NP_473433.2"
                     /db_xref="CCDS:CCDS36695.1"
                     /db_xref="GeneID:117066"
                     /db_xref="MGI:MGI:2151929"
                     /translation="MTPAVFLAILWLVMASSSPSPDPILDAEWQKWKIKYGKTYSLEE
                     EGQKRAVWEENMKKIKLHNGENGLGKHGFTMEMNAFGDMTLEEFRKEMIEIPVPTVKK
                     GKSVQKRLSVNLPKFINWKKRGYVTPVRTQIACNSCWAISVTGAIEGQMFRKTGQLIP
                     LSVQNLVDCVDGSGCHAGSVLDSFKYLMEKGGLESEATYPYEDKQGSCRYNPENSTAS
                     ITGFEFIPNNEVDLMSAVASLGPISVVIDAWHESFLFYKRGIYYEPNCNNSLFALRHA
                     VLLVGYGFIGRESEGRKYWIIKNSLGTKWGYKGYMKIAKDQGNHCGIASLPVFPRV"
     exon            219..341
                     /gene="Cts3"
                     /gene_synonym="1600000I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            342..488
                     /gene="Cts3"
                     /gene_synonym="1600000I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            489..704
                     /gene="Cts3"
                     /gene_synonym="1600000I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            705..867
                     /gene="Cts3"
                     /gene_synonym="1600000I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            868..991
                     /gene="Cts3"
                     /gene_synonym="1600000I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            992..1367
                     /gene="Cts3"
                     /gene_synonym="1600000I23Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggggaattaa gtaacctttg gaaagattgc agtggaccag ggaagcaaca gtcaccacag
       61 gtggcatcct gcatccacca gagtagaaaa atatgactcc tgctgtcttc ctggccatct
      121 tgtggttggt aatggcctca tcatcaccat cacctgatcc cattttggat gctgaatggc
      181 agaagtggaa aataaaatat ggaaaaacat acagtctgga ggaagaagga cagaagagag
      241 cagtatggga agaaaatatg aaaaagatca aactgcacaa tggggagaat ggcctgggga
      301 agcatggttt caccatggaa atgaatgcct ttggtgacat gacacttgaa gaattcagga
      361 aagagatgat tgaaatccca gtcccaactg tcaagaaagg gaaaagtgtc cagaaacgtc
      421 tgtctgttaa cctgcccaag tttataaact ggaaaaagag aggctatgtt actcctgtgc
      481 ggacacagat tgcatgtaat tcttgttggg ctatttctgt tactggtgcc atagaaggac
      541 agatgttccg gaaaacaggc caactgatcc ctctgagtgt acagaaccta gtggactgtg
      601 ttgacggaag tggctgtcat gcaggcagtg tgttagattc ttttaagtat ttgatggaaa
      661 agggaggtct agagtctgag gcaacctatc catatgaaga caagcaagga tcatgcaggt
      721 acaatccaga gaattctact gctagtatca caggctttga gtttatccca aacaatgagg
      781 ttgacctaat gagtgctgtg gcaagtcttg ggcccatttc tgttgtaatc gatgcatggc
      841 atgaatcttt cctgttctat aaaagaggta tatattatga gccaaactgc aataacagtt
      901 tatttgctct cagacatgct gtgctactgg ttggctatgg ttttatagga agagaatcag
      961 aaggcaggaa atactggatc atcaagaaca gcctgggtac aaaatggggc tataaaggct
     1021 atatgaagat tgccaaagac cagggaaacc actgtggaat tgcttcactt cccgttttcc
     1081 ccagagtgtg aactgcctgg tgctgacaag gaaggaatgg acagaagaca ccatgtagag
     1141 aagaggcact tccatttcaa aacagcgggt cactgcagtg aatatgagac actgcagtca
     1201 ctgaaaatcc agttgtgatg tcaagtttgt gacacattta ttctcaaaag acatgaccat
     1261 tactgtaact gatgtcatac actggtttgt ttttgttttc tataacaatg ttatcttttt
     1321 tctgtaacaa attaagtctt tagaaataaa ggtttattta aatgttaaaa aaaaaaaaaa
     1381 a
//
